ATE412634T1 - Piperazinderivate von alkyloxindolen - Google Patents
Piperazinderivate von alkyloxindolenInfo
- Publication number
- ATE412634T1 ATE412634T1 AT05745442T AT05745442T ATE412634T1 AT E412634 T1 ATE412634 T1 AT E412634T1 AT 05745442 T AT05745442 T AT 05745442T AT 05745442 T AT05745442 T AT 05745442T AT E412634 T1 ATE412634 T1 AT E412634T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyloxindoles
- piperazine derivatives
- derivatives
- new
- disorders
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical class C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000005625 indol-2-ones Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0400954A HU0400954D0 (en) | 2004-05-11 | 2004-05-11 | Piperazine derivatives of alkyl oxindoles |
HU0500461A HUP0500461A3 (en) | 2005-05-05 | 2005-05-05 | Pyperazine derivatives of alkyl-oxindoles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE412634T1 true ATE412634T1 (de) | 2008-11-15 |
Family
ID=89985994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05745442T ATE412634T1 (de) | 2004-05-11 | 2005-05-10 | Piperazinderivate von alkyloxindolen |
Country Status (24)
Country | Link |
---|---|
US (1) | US20070219209A1 (de) |
EP (1) | EP1751106B1 (de) |
JP (1) | JP2007537226A (de) |
KR (1) | KR20070011551A (de) |
AT (1) | ATE412634T1 (de) |
AU (1) | AU2005240842B2 (de) |
BG (1) | BG109768A (de) |
CA (1) | CA2564009A1 (de) |
CZ (1) | CZ2006778A3 (de) |
DE (1) | DE602005010694D1 (de) |
DK (1) | DK1751106T3 (de) |
EA (1) | EA011280B1 (de) |
ES (1) | ES2317241T3 (de) |
HR (2) | HRP20060401A2 (de) |
IL (1) | IL178759A0 (de) |
MX (1) | MXPA06013064A (de) |
NO (1) | NO20065697L (de) |
NZ (1) | NZ551542A (de) |
PL (1) | PL1751106T3 (de) |
PT (1) | PT1751106E (de) |
RS (1) | RS20060620A (de) |
SI (1) | SI1751106T1 (de) |
SK (1) | SK51112006A3 (de) |
WO (1) | WO2005108363A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1776339E (pt) * | 2004-05-11 | 2009-09-16 | Egis Gyogyszergyar Nyrt | Derivados de 3-(((4-fenil)-piperazin-1-il)-alquil)-3-alquil- 1,3-di-hidro-2h-indol-2-ona e compostos relacionados para o tratamento de desordens do sistema nervoso central |
CN106243088B (zh) | 2015-06-03 | 2019-01-04 | 广东东阳光药业有限公司 | 取代的哌嗪化合物及其使用方法和用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
MX173362B (es) * | 1987-03-02 | 1994-02-23 | Pfizer | Compuestos de piperazinil heterociclicos y procedimiento para su preparacion |
FR2635104B1 (fr) * | 1988-08-03 | 1992-04-30 | Synthelabo | Derives d'indolone, leur preparation et leur application en therapeutique |
GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
WO1998008816A1 (fr) * | 1996-08-26 | 1998-03-05 | Meiji Seika Kaisha, Ltd. | Derives d'indoxyle et psychotropes |
-
2005
- 2005-05-10 WO PCT/HU2005/000048 patent/WO2005108363A1/en active Application Filing
- 2005-05-10 SK SK5111-2006A patent/SK51112006A3/sk not_active Application Discontinuation
- 2005-05-10 CA CA002564009A patent/CA2564009A1/en not_active Abandoned
- 2005-05-10 DE DE602005010694T patent/DE602005010694D1/de active Active
- 2005-05-10 AT AT05745442T patent/ATE412634T1/de active
- 2005-05-10 PL PL05745442T patent/PL1751106T3/pl unknown
- 2005-05-10 PT PT05745442T patent/PT1751106E/pt unknown
- 2005-05-10 NZ NZ551542A patent/NZ551542A/en unknown
- 2005-05-10 SI SI200530563T patent/SI1751106T1/sl unknown
- 2005-05-10 US US11/596,466 patent/US20070219209A1/en not_active Abandoned
- 2005-05-10 KR KR1020067025135A patent/KR20070011551A/ko not_active Application Discontinuation
- 2005-05-10 DK DK05745442T patent/DK1751106T3/da active
- 2005-05-10 JP JP2007512356A patent/JP2007537226A/ja active Pending
- 2005-05-10 ES ES05745442T patent/ES2317241T3/es active Active
- 2005-05-10 RS RSP-2006/0620A patent/RS20060620A/sr unknown
- 2005-05-10 AU AU2005240842A patent/AU2005240842B2/en not_active Ceased
- 2005-05-10 CZ CZ20060778A patent/CZ2006778A3/cs unknown
- 2005-05-10 EA EA200602080A patent/EA011280B1/ru not_active IP Right Cessation
- 2005-05-10 MX MXPA06013064A patent/MXPA06013064A/es active IP Right Grant
- 2005-05-10 EP EP05745442A patent/EP1751106B1/de active Active
-
2006
- 2006-10-19 IL IL178759A patent/IL178759A0/en unknown
- 2006-11-20 HR HR20060401A patent/HRP20060401A2/xx not_active Application Discontinuation
- 2006-12-11 BG BG109768A patent/BG109768A/bg unknown
- 2006-12-11 NO NO20065697A patent/NO20065697L/no not_active Application Discontinuation
-
2009
- 2009-01-29 HR HR20090054T patent/HRP20090054T3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU2005240842B2 (en) | 2011-10-06 |
EA011280B1 (ru) | 2009-02-27 |
US20070219209A1 (en) | 2007-09-20 |
MXPA06013064A (es) | 2007-04-27 |
DK1751106T3 (da) | 2009-03-09 |
AU2005240842A1 (en) | 2005-11-17 |
DE602005010694D1 (de) | 2008-12-11 |
NO20065697L (no) | 2007-02-02 |
PT1751106E (pt) | 2009-02-10 |
EP1751106B1 (de) | 2008-10-29 |
WO2005108363A1 (en) | 2005-11-17 |
HRP20090054T3 (en) | 2009-03-31 |
JP2007537226A (ja) | 2007-12-20 |
CZ2006778A3 (cs) | 2007-03-07 |
EP1751106A1 (de) | 2007-02-14 |
SK51112006A3 (sk) | 2007-05-03 |
NZ551542A (en) | 2010-06-25 |
IL178759A0 (en) | 2007-02-11 |
ES2317241T3 (es) | 2009-04-16 |
HRP20060401A2 (en) | 2007-03-31 |
PL1751106T3 (pl) | 2009-07-31 |
EA200602080A1 (ru) | 2007-04-27 |
RS20060620A (en) | 2008-09-29 |
CA2564009A1 (en) | 2005-11-17 |
KR20070011551A (ko) | 2007-01-24 |
SI1751106T1 (sl) | 2009-06-30 |
BG109768A (bg) | 2008-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
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