DK1751106T3 - Piperazinderivater af alkyloxindoler - Google Patents

Piperazinderivater af alkyloxindoler

Info

Publication number
DK1751106T3
DK1751106T3 DK05745442T DK05745442T DK1751106T3 DK 1751106 T3 DK1751106 T3 DK 1751106T3 DK 05745442 T DK05745442 T DK 05745442T DK 05745442 T DK05745442 T DK 05745442T DK 1751106 T3 DK1751106 T3 DK 1751106T3
Authority
DK
Denmark
Prior art keywords
alkyloxindoles
piperazine derivatives
derivatives
new
disorders
Prior art date
Application number
DK05745442T
Other languages
English (en)
Inventor
Balazs Volk
Jozsef Barkeczy
Gyula Simig
Tibor Mezei
Dezsofi Rita Kapillerne
Istvan Gacsalyi
Katalin Pallagi
Gabor Gigler
Gyoergy Levay
Krisztina Mericz
Csilla Leveleki
Nora Sziray
Gabor Szenesi
Andras Egyed
Laszlo Gabor Harsing
Original Assignee
Egis Gyogyszergyar Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU0400954A external-priority patent/HU0400954D0/hu
Priority claimed from HU0500461A external-priority patent/HUP0500461A3/hu
Application filed by Egis Gyogyszergyar Nyrt filed Critical Egis Gyogyszergyar Nyrt
Application granted granted Critical
Publication of DK1751106T3 publication Critical patent/DK1751106T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DK05745442T 2004-05-11 2005-05-10 Piperazinderivater af alkyloxindoler DK1751106T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU0400954A HU0400954D0 (en) 2004-05-11 2004-05-11 Piperazine derivatives of alkyl oxindoles
HU0500461A HUP0500461A3 (en) 2005-05-05 2005-05-05 Pyperazine derivatives of alkyl-oxindoles
PCT/HU2005/000048 WO2005108363A1 (en) 2004-05-11 2005-05-10 Piperazine derivatives of alkyl oxindoles

Publications (1)

Publication Number Publication Date
DK1751106T3 true DK1751106T3 (da) 2009-03-09

Family

ID=89985994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05745442T DK1751106T3 (da) 2004-05-11 2005-05-10 Piperazinderivater af alkyloxindoler

Country Status (24)

Country Link
US (1) US20070219209A1 (da)
EP (1) EP1751106B1 (da)
JP (1) JP2007537226A (da)
KR (1) KR20070011551A (da)
AT (1) ATE412634T1 (da)
AU (1) AU2005240842B2 (da)
BG (1) BG109768A (da)
CA (1) CA2564009A1 (da)
CZ (1) CZ2006778A3 (da)
DE (1) DE602005010694D1 (da)
DK (1) DK1751106T3 (da)
EA (1) EA011280B1 (da)
ES (1) ES2317241T3 (da)
HR (2) HRP20060401A2 (da)
IL (1) IL178759A0 (da)
MX (1) MXPA06013064A (da)
NO (1) NO20065697L (da)
NZ (1) NZ551542A (da)
PL (1) PL1751106T3 (da)
PT (1) PT1751106E (da)
RS (1) RS20060620A (da)
SI (1) SI1751106T1 (da)
SK (1) SK51112006A3 (da)
WO (1) WO2005108363A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007537229A (ja) * 2004-05-11 2007-12-20 エギシュ ヂョヂセルヂャール エンニュ・エル・テー ジアルキルオキシインドールの新規なピペラジン誘導体
US10316025B2 (en) 2015-06-03 2019-06-11 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
FR2635104B1 (fr) * 1988-08-03 1992-04-30 Synthelabo Derives d'indolone, leur preparation et leur application en therapeutique
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
WO1998008816A1 (fr) * 1996-08-26 1998-03-05 Meiji Seika Kaisha, Ltd. Derives d'indoxyle et psychotropes

Also Published As

Publication number Publication date
ES2317241T3 (es) 2009-04-16
PT1751106E (pt) 2009-02-10
MXPA06013064A (es) 2007-04-27
ATE412634T1 (de) 2008-11-15
US20070219209A1 (en) 2007-09-20
EA011280B1 (ru) 2009-02-27
DE602005010694D1 (de) 2008-12-11
KR20070011551A (ko) 2007-01-24
SI1751106T1 (sl) 2009-06-30
PL1751106T3 (pl) 2009-07-31
EP1751106A1 (en) 2007-02-14
EA200602080A1 (ru) 2007-04-27
SK51112006A3 (sk) 2007-05-03
AU2005240842A1 (en) 2005-11-17
BG109768A (bg) 2008-03-31
JP2007537226A (ja) 2007-12-20
NZ551542A (en) 2010-06-25
IL178759A0 (en) 2007-02-11
EP1751106B1 (en) 2008-10-29
CZ2006778A3 (cs) 2007-03-07
CA2564009A1 (en) 2005-11-17
RS20060620A (en) 2008-09-29
HRP20090054T3 (en) 2009-03-31
AU2005240842B2 (en) 2011-10-06
HRP20060401A2 (en) 2007-03-31
WO2005108363A1 (en) 2005-11-17
NO20065697L (no) 2007-02-02

Similar Documents

Publication Publication Date Title
NO20056130L (no) Nye substituerte 3-svovelindoler
SE0303180D0 (sv) Novel compounds
SE0302232D0 (sv) Novel Compounds
EA201100749A1 (ru) Производные пиридина и пиримидина в качестве ингибиторов фосфодиэстеразы 10
EA200702470A1 (ru) Производные пиррола в качестве положительных аллостерических модуляторов метаботропных глутаматных рецепторов
CY1111206T1 (el) Βενζοθειοφαινια υποκατεστημενα με πιπεραζινη για την αγωγη διανοητικων διαταραχων
EA200700909A1 (ru) Азаиндолкарбоксамиды
ATE467632T1 (de) Pyrroloä2,3-büpyridinderivate als modulatoren des h3-rezeptors
ATE449776T1 (de) Pyrroloä2,3-cüpyridinderivate
EA200801120A1 (ru) Нафтильные производные в качестве ингибиторов агрегирования бета-амилоида
DK1751106T3 (da) Piperazinderivater af alkyloxindoler
EA200602081A1 (ru) Пиридиновые производные алкилоксиндолов в качестве агентов, активных в отношении рецептора 5-нт7
ATE421505T1 (de) 4-aminobenzofuranverbindungen als phosphodiesterase-4-inhibitoren
EA200602083A1 (ru) Новые пиперазиновые производные диалкилоксиндолов
HRP20060420A2 (en) Piperazine derivatives of alkyl oxindoles
ATE534638T1 (de) Piperazin-derivate
IL179030A0 (en) Indol-2-one derivatives for the treatment of central nervous disorders, gastrointestinal disorders and cardiovascular disorders
UA86809C2 (en) Piperazine derivatives of alkyl oxindoles
ATE423772T1 (de) Morpholinderivate als inhibitoren der wiederaufnahme von norepinephrin
ATE479691T1 (de) 4,5,6,7-tetrahydrothienoä2,3-cüpyridine als h3- modulatoren
MY141048A (en) Morpholine derivatives as norepinephrine reuptake inhibitors
SE0301795D0 (sv) New use I