NO20062489L - Heterocykliske anti-migrenemidler - Google Patents
Heterocykliske anti-migrenemidlerInfo
- Publication number
- NO20062489L NO20062489L NO20062489A NO20062489A NO20062489L NO 20062489 L NO20062489 L NO 20062489L NO 20062489 A NO20062489 A NO 20062489A NO 20062489 A NO20062489 A NO 20062489A NO 20062489 L NO20062489 L NO 20062489L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- methods
- migraine agents
- receptors
- neurogenic
- Prior art date
Links
- 229940125684 antimigraine agent Drugs 0.000 title 1
- 239000002282 antimigraine agent Substances 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 102000014468 Calcitonin Gene-Related Peptide Receptors Human genes 0.000 abstract 3
- 108010078311 Calcitonin Gene-Related Peptide Receptors Proteins 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010019233 Headaches Diseases 0.000 abstract 1
- 208000033830 Hot Flashes Diseases 0.000 abstract 1
- 206010060800 Hot flush Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000007920 Neurogenic Inflammation Diseases 0.000 abstract 1
- 206010047141 Vasodilatation Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 230000008485 antagonism Effects 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 230000005796 circulatory shock Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000009245 menopause Effects 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000001272 neurogenic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000024883 vasodilation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52743803P | 2003-12-05 | 2003-12-05 | |
| US11/004,706 US7569578B2 (en) | 2003-12-05 | 2004-12-03 | Heterocyclic anti-migraine agents |
| PCT/US2004/040721 WO2005056550A2 (en) | 2003-12-05 | 2004-12-06 | Heterocyclic anti-migraine agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20062489L true NO20062489L (no) | 2006-06-14 |
Family
ID=34680800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20062489A NO20062489L (no) | 2003-12-05 | 2006-05-31 | Heterocykliske anti-migrenemidler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7569578B2 (pt) |
| EP (1) | EP1689738A2 (pt) |
| JP (1) | JP2007516967A (pt) |
| KR (1) | KR20070026339A (pt) |
| AR (1) | AR046787A1 (pt) |
| AU (1) | AU2004297230A1 (pt) |
| BR (1) | BRPI0417337A (pt) |
| CA (1) | CA2549401A1 (pt) |
| CO (1) | CO5690595A2 (pt) |
| IL (1) | IL176043A0 (pt) |
| IS (1) | IS8483A (pt) |
| MX (1) | MXPA06005970A (pt) |
| NO (1) | NO20062489L (pt) |
| PE (1) | PE20050670A1 (pt) |
| RU (1) | RU2006124026A (pt) |
| TW (1) | TW200524601A (pt) |
| WO (1) | WO2005056550A2 (pt) |
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| US7220862B2 (en) | 2002-06-05 | 2007-05-22 | Bristol-Myers Squibb Company | Calcitonin gene related peptide receptor antagonists |
| US20040063735A1 (en) * | 2002-06-05 | 2004-04-01 | Chaturvedula Prasad V. | Calcitonin gene related peptide receptor antagonists |
| US7842808B2 (en) * | 2002-06-05 | 2010-11-30 | Bristol-Myers Squibb Company | Anti-migraine spirocycles |
| AR046787A1 (es) | 2003-12-05 | 2005-12-21 | Bristol Myers Squibb Co | Agentes antimigrana heterociclicos |
| US7820673B2 (en) * | 2003-12-17 | 2010-10-26 | Takeda Pharmaceutical Company Limited | Urea derivative, process for producing the same, and use |
| TW200533398A (en) * | 2004-03-29 | 2005-10-16 | Bristol Myers Squibb Co | Novel therapeutic agents for the treatment of migraine |
| US7453002B2 (en) | 2004-06-15 | 2008-11-18 | Bristol-Myers Squibb Company | Five-membered heterocycles useful as serine protease inhibitors |
| US7384931B2 (en) * | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
| US7384930B2 (en) * | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
| US7449586B2 (en) * | 2004-12-03 | 2008-11-11 | Bristol-Myers Squibb Company | Processes for the preparation of CGRP-receptor antagonists and intermediates thereof |
| US7834007B2 (en) * | 2005-08-25 | 2010-11-16 | Bristol-Myers Squibb Company | CGRP antagonists |
| US8168592B2 (en) | 2005-10-21 | 2012-05-01 | Amgen Inc. | CGRP peptide antagonists and conjugates |
| JP2010508358A (ja) * | 2006-11-01 | 2010-03-18 | ブリストル−マイヤーズ スクイブ カンパニー | グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の調節剤、並びにその使用 |
| WO2008057856A2 (en) * | 2006-11-01 | 2008-05-15 | Bristol-Myers Squibb Company | Modulators of glucocorticoid receptor, ap-1 and/or nf-kappab activity and use thereof |
| DE102007002717A1 (de) | 2007-01-18 | 2008-07-24 | Merck Patent Gmbh | Heterocyclische Indazolderivate |
| DE102007022565A1 (de) | 2007-05-14 | 2008-11-20 | Merck Patent Gmbh | Heterocyclische Indazolderivate |
| ES2432068T3 (es) | 2008-06-09 | 2013-11-29 | Bayer Intellectual Property Gmbh | 4-(Indazolil)-1,4-dihidropiridinas sustituidas y procedimientos de uso de las mismas |
| DE102008038220A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | Oxadiazolderivate |
| DE102008038221A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | 7-Azaindolderivate |
| DE102008038222A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | Indazol-5-carbonsäurehydrazid-derivate |
| CA2752603C (en) | 2009-02-18 | 2016-04-05 | Bayer Pharma Aktiengesellschaft | Bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives and uses thereof |
| CA2767476A1 (en) | 2009-07-10 | 2011-01-13 | Bayer Pharma Aktiengesellschaft | Indazolyl-substituted dihydroisoxazolopyridines and methods of use thereof |
| EP2565186A1 (en) * | 2011-09-02 | 2013-03-06 | Hybrigenics S.A. | Selective and reversible inhibitors of ubiquitin specific protease 7 |
| KR20150033652A (ko) | 2012-06-20 | 2015-04-01 | 노파르티스 아게 | 보체 경로 조절제 및 그의 용도 |
| US9695176B2 (en) | 2012-10-18 | 2017-07-04 | Bristol-Myers Squibb Company | Substituted imidazo[1,5-a]pyrazines as CGRP receptor antagonists |
| NZ708350A (en) | 2012-11-20 | 2016-08-26 | Merial Inc | Anthelmintic compounds and compositions and method of using thereof |
| JP6521977B2 (ja) | 2013-09-06 | 2019-05-29 | オーリジーン ディスカバリー テクノロジーズ リミテッドＡｕｒｉｇｅｎｅ Ｄｉｓｃｏｖｅｒｙ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｉｍｉｔｅｄ | 免疫調節剤としての１，２，４−オキサジアゾール誘導体 |
| EP3267984B1 (en) * | 2015-03-10 | 2021-11-24 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| JOP20200116A1 (ar) | 2015-04-24 | 2017-06-16 | Amgen Inc | طرق لعلاج أو الوقاية من الصداع النصفي |
| GB201519195D0 (en) | 2015-10-30 | 2015-12-16 | Heptares Therapeutics Ltd | CGRP Receptor Antagonists |
| GB201519196D0 (en) | 2015-10-30 | 2015-12-16 | Heptares Therapeutics Ltd | CGRP Receptor Antagonists |
| GB201519194D0 (en) | 2015-10-30 | 2015-12-16 | Heptares Therapeutics Ltd | CGRP receptor antagonists |
| WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
| SG11202003081WA (en) | 2017-10-11 | 2020-05-28 | Aurigene Discovery Tech Ltd | Crystalline forms of 3-substituted 1,2,4-oxadiazole |
| JP7378394B2 (ja) | 2017-11-03 | 2023-11-13 | オーリジーン オンコロジー リミテッド | Ｔｉｍ－３およびｐｄ－１経路の二重阻害剤 |
| JP7378395B2 (ja) | 2017-11-06 | 2023-11-13 | オーリジーン オンコロジー リミテッド | 免疫調節のためのコンジョイントセラピー |
| JP7339262B2 (ja) | 2018-01-12 | 2023-09-05 | アムジェン インコーポレイテッド | Ｐａｃ１抗体及びその使用 |
| WO2022172829A1 (ja) * | 2021-02-15 | 2022-08-18 | 株式会社カネカ | 光学活性インダゾリルアラニン又はインダゾリルアルデヒドの製造方法 |
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| AU2004222378B2 (en) | 2003-03-14 | 2008-08-14 | Merck Sharp & Dohme Corp. | Carboxamide spirohydantoin CGRP receptor antagonists |
| US20040248816A1 (en) | 2003-04-01 | 2004-12-09 | Boehringer Ingelheim International Gmbh | Treatment of migraine |
| JO2355B1 (en) | 2003-04-15 | 2006-12-12 | ميرك شارب اند دوم كوربوريشن | Hereditary calcitonin polypeptide receptor antagonists |
| JP4705908B2 (ja) | 2003-04-15 | 2011-06-22 | メルク・シャープ・エンド・ドーム・コーポレイション | Ｃｇｒｐ受容体拮抗薬 |
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| DE102004015723A1 (de) | 2004-03-29 | 2005-10-20 | Boehringer Ingelheim Pharma | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| DE102004018794A1 (de) | 2004-04-15 | 2005-10-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
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| WO2005102322A1 (de) | 2004-04-20 | 2005-11-03 | Boehringer Ingelheim International Gmbh | Verwendung eines cgrp-antagonisten in kombination mit einem serotonin-wiederaufnahme-hemmer zur behandlung von migräne |
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| DE102004019492A1 (de) | 2004-04-22 | 2005-11-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| US7696195B2 (en) | 2004-04-22 | 2010-04-13 | Boehringer Ingelheim International Gmbh | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions |
| DE102004027912A1 (de) | 2004-06-09 | 2005-12-29 | Grünenthal GmbH | Substituierte Cyclopenten-Verbindungen |
| US7384930B2 (en) | 2004-11-03 | 2008-06-10 | Bristol-Myers Squibb Company | Constrained compounds as CGRP-receptor antagonists |
| US7449586B2 (en) | 2004-12-03 | 2008-11-11 | Bristol-Myers Squibb Company | Processes for the preparation of CGRP-receptor antagonists and intermediates thereof |
-
2004
- 2004-12-03 AR ARP040104529A patent/AR046787A1/es unknown
- 2004-12-03 TW TW093137539A patent/TW200524601A/zh unknown
- 2004-12-03 US US11/004,706 patent/US7569578B2/en active Active
- 2004-12-06 PE PE2004001195A patent/PE20050670A1/es not_active Application Discontinuation
- 2004-12-06 CA CA002549401A patent/CA2549401A1/en not_active Abandoned
- 2004-12-06 JP JP2006542841A patent/JP2007516967A/ja not_active Withdrawn
- 2004-12-06 RU RU2006124026/04A patent/RU2006124026A/ru not_active Application Discontinuation
- 2004-12-06 KR KR1020067010916A patent/KR20070026339A/ko not_active Application Discontinuation
- 2004-12-06 EP EP04813096A patent/EP1689738A2/en not_active Withdrawn
- 2004-12-06 WO PCT/US2004/040721 patent/WO2005056550A2/en active Application Filing
- 2004-12-06 MX MXPA06005970A patent/MXPA06005970A/es not_active Application Discontinuation
- 2004-12-06 BR BRPI0417337-6A patent/BRPI0417337A/pt not_active IP Right Cessation
- 2004-12-06 AU AU2004297230A patent/AU2004297230A1/en not_active Abandoned
-
2006
- 2006-05-26 IS IS8483A patent/IS8483A/is unknown
- 2006-05-31 IL IL176043A patent/IL176043A0/en unknown
- 2006-05-31 NO NO20062489A patent/NO20062489L/no not_active Application Discontinuation
- 2006-06-01 CO CO06052775A patent/CO5690595A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20050670A1 (es) | 2005-09-25 |
| WO2005056550A3 (en) | 2005-07-14 |
| CA2549401A1 (en) | 2005-06-23 |
| AR046787A1 (es) | 2005-12-21 |
| RU2006124026A (ru) | 2008-01-27 |
| KR20070026339A (ko) | 2007-03-08 |
| IL176043A0 (en) | 2006-10-05 |
| WO2005056550A2 (en) | 2005-06-23 |
| CO5690595A2 (es) | 2006-10-31 |
| AU2004297230A1 (en) | 2005-06-23 |
| MXPA06005970A (es) | 2006-07-06 |
| EP1689738A2 (en) | 2006-08-16 |
| TW200524601A (en) | 2005-08-01 |
| BRPI0417337A (pt) | 2007-04-17 |
| US7569578B2 (en) | 2009-08-04 |
| JP2007516967A (ja) | 2007-06-28 |
| IS8483A (is) | 2006-05-26 |
| US20050153959A1 (en) | 2005-07-14 |
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