NO20061656L - 2,4 di(hetero)-arylamino-pyrimidin derivaer som ZAP-70 og/aller SYK inhibitorer - Google Patents

2,4 di(hetero)-arylamino-pyrimidin derivaer som ZAP-70 og/aller SYK inhibitorer

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Publication number
NO20061656L
NO20061656L NO20061656A NO20061656A NO20061656L NO 20061656 L NO20061656 L NO 20061656L NO 20061656 A NO20061656 A NO 20061656A NO 20061656 A NO20061656 A NO 20061656A NO 20061656 L NO20061656 L NO 20061656L
Authority
NO
Norway
Prior art keywords
zap
arylamino
hetero
pyrimidine derivatives
syk inhibitors
Prior art date
Application number
NO20061656A
Other languages
English (en)
Inventor
Rudolf Duthaler
Gebhard Thoma
Nigel Graham Cooke
Gerhard Zenke
Klaus Hinterding
Anette Von Matt
Rolf Baentell
Marie Claude Bernhard
Peter Buchlmayer
Maurice Van Eis
Louis Walliser
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20061656L publication Critical patent/NO20061656L/no

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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Abstract

Beskrevet er pyrimidinderivater med formel I hvori R0, R1, R3 til R9, og Z har betydningene som indikert i krav 1, som har ZAP -70 og/eller Syk inhiberingsaktiviteter.
NO20061656A 2003-09-16 2006-04-11 2,4 di(hetero)-arylamino-pyrimidin derivaer som ZAP-70 og/aller SYK inhibitorer NO20061656L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0321710.6A GB0321710D0 (en) 2003-09-16 2003-09-16 Organic compounds
GBGB0414440.8A GB0414440D0 (en) 2003-09-16 2004-06-28 Organic compounds
PCT/EP2004/010348 WO2005026158A1 (en) 2003-09-16 2004-09-15 2,4 di (hetero) -arylamino-pyrimidine derivatives as zap-70 and/or syk inhibitors

Publications (1)

Publication Number Publication Date
NO20061656L true NO20061656L (no) 2006-06-16

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ID=29227205

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NO20061656A NO20061656L (no) 2003-09-16 2006-04-11 2,4 di(hetero)-arylamino-pyrimidin derivaer som ZAP-70 og/aller SYK inhibitorer

Country Status (28)

Country Link
US (2) US7671063B2 (no)
EP (2) EP1664035B1 (no)
JP (1) JP4504375B2 (no)
KR (1) KR100813384B1 (no)
CN (2) CN1882578B (no)
AR (1) AR045747A1 (no)
AT (1) ATE498623T1 (no)
AU (1) AU2004272283B9 (no)
BR (1) BRPI0414480A (no)
CA (1) CA2538909A1 (no)
DE (1) DE602004031436D1 (no)
EC (1) ECSP066424A (no)
ES (2) ES2361412T3 (no)
GB (2) GB0321710D0 (no)
IL (1) IL174217A0 (no)
IS (1) IS8402A (no)
MA (1) MA28076A1 (no)
MX (1) MXPA06002966A (no)
NO (1) NO20061656L (no)
PE (1) PE20050429A1 (no)
PL (1) PL1664035T3 (no)
PT (1) PT1664035E (no)
RU (1) RU2403251C2 (no)
SG (1) SG132676A1 (no)
TN (1) TNSN06083A1 (no)
TW (1) TW200521118A (no)
WO (1) WO2005026158A1 (no)
ZA (1) ZA200601963B (no)

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TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
GB0206215D0 (en) * 2002-03-15 2002-05-01 Novartis Ag Organic compounds
AU2003265336B8 (en) 2002-07-29 2009-04-23 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
GB0305929D0 (en) * 2003-03-14 2003-04-23 Novartis Ag Organic compounds
PL1656372T3 (pl) 2003-07-30 2013-08-30 Rigel Pharmaceuticals Inc Związki 2,4-pirymidynodiaminy do stosowania w leczeniu lub zapobieganiu chorobom autoimmunologicznym
BRPI0413616B8 (pt) * 2003-08-15 2021-05-25 Irm Llc 2,4-pirimidinadiaminas, seus usos, e composição farmacêutica
GB0321710D0 (en) * 2003-09-16 2003-10-15 Novartis Ag Organic compounds
MX2007007189A (es) 2005-01-19 2010-09-28 Rigel Pharmaceuticals Inc Prodrogas de compuestos de 2,4-pirimidindiamina y sus usos.
US7968538B2 (en) * 2005-01-25 2011-06-28 Galenea Corp. Substituted arylamine compounds and methods of treatment
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