PL1664035T3 - Pochodne 2,4-di-(hetero)-aryloamino-pirymidyny jako inhibitory ZAP-70 i/lub SYK - Google Patents

Pochodne 2,4-di-(hetero)-aryloamino-pirymidyny jako inhibitory ZAP-70 i/lub SYK

Info

Publication number
PL1664035T3
PL1664035T3 PL04786952T PL04786952T PL1664035T3 PL 1664035 T3 PL1664035 T3 PL 1664035T3 PL 04786952 T PL04786952 T PL 04786952T PL 04786952 T PL04786952 T PL 04786952T PL 1664035 T3 PL1664035 T3 PL 1664035T3
Authority
PL
Poland
Prior art keywords
zap
arylamino
hetero
pyrimidine derivatives
syk inhibitors
Prior art date
Application number
PL04786952T
Other languages
English (en)
Inventor
Rolf Baenteli
Marie Claude Bernhard
Peter Buehlmayer
Nigel Graham Cooke
Rudolf Duthaler
Klaus Hinterding
Gebhard Thoma
Eis Maurice Van
Matt Anette Von
Louis Walliser
Gerhard Zenke
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL1664035T3 publication Critical patent/PL1664035T3/pl

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    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
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  • Urology & Nephrology (AREA)
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PL04786952T 2003-09-16 2004-09-15 Pochodne 2,4-di-(hetero)-aryloamino-pirymidyny jako inhibitory ZAP-70 i/lub SYK PL1664035T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0321710.6A GB0321710D0 (en) 2003-09-16 2003-09-16 Organic compounds
GBGB0414440.8A GB0414440D0 (en) 2003-09-16 2004-06-28 Organic compounds
EP04786952A EP1664035B1 (en) 2003-09-16 2004-09-15 2,4 di(hetero)-arylamino-pyrimidine derivatives as zap-70 and/or syk inhibitors
PCT/EP2004/010348 WO2005026158A1 (en) 2003-09-16 2004-09-15 2,4 di (hetero) -arylamino-pyrimidine derivatives as zap-70 and/or syk inhibitors

Publications (1)

Publication Number Publication Date
PL1664035T3 true PL1664035T3 (pl) 2011-07-29

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PL04786952T PL1664035T3 (pl) 2003-09-16 2004-09-15 Pochodne 2,4-di-(hetero)-aryloamino-pirymidyny jako inhibitory ZAP-70 i/lub SYK

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Country Link
US (2) US7671063B2 (pl)
EP (2) EP1664035B1 (pl)
JP (1) JP4504375B2 (pl)
KR (1) KR100813384B1 (pl)
CN (2) CN102260248A (pl)
AR (1) AR045747A1 (pl)
AT (1) ATE498623T1 (pl)
AU (1) AU2004272283B9 (pl)
BR (1) BRPI0414480A (pl)
CA (1) CA2538909A1 (pl)
DE (1) DE602004031436D1 (pl)
EC (1) ECSP066424A (pl)
ES (2) ES2361412T3 (pl)
GB (2) GB0321710D0 (pl)
IL (1) IL174217A0 (pl)
IS (1) IS8402A (pl)
MA (1) MA28076A1 (pl)
MX (1) MXPA06002966A (pl)
NO (1) NO20061656L (pl)
PE (1) PE20050429A1 (pl)
PL (1) PL1664035T3 (pl)
PT (1) PT1664035E (pl)
RU (1) RU2403251C2 (pl)
SG (1) SG132676A1 (pl)
TN (1) TNSN06083A1 (pl)
TW (1) TW200521118A (pl)
WO (1) WO2005026158A1 (pl)
ZA (1) ZA200601963B (pl)

Families Citing this family (135)

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TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
GB0206215D0 (en) * 2002-03-15 2002-05-01 Novartis Ag Organic compounds
HRP20050089B1 (hr) 2002-07-29 2015-06-19 Rigel Pharmaceuticals Upotreba 2,4 pirimidindiaminskog spoja za proizvodnju lijeka za lijeäśenje ili sprjeäśavanje autoimunosne bolesti
GB0305929D0 (en) * 2003-03-14 2003-04-23 Novartis Ag Organic compounds
WO2005012294A1 (en) 2003-07-30 2005-02-10 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
PT1660458E (pt) * 2003-08-15 2012-04-27 Novartis Ag 2,4-pirimidinodiaminas úteis no tratamento de doenças neoplásicas, desordens inflamatórias e do sistema imunitário
GB0321710D0 (en) * 2003-09-16 2003-10-15 Novartis Ag Organic compounds
AU2006206458B2 (en) 2005-01-19 2012-10-25 Rigel Pharmaceuticals, Inc. Prodrugs of 2,4-pyrimidinediamine compounds and their uses
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