NO20056174L - Levering av et aktivt legemiddel til den posteriore del av oyet via subkonjunktiv eller periokular levering av et prolegemiddel - Google Patents
Levering av et aktivt legemiddel til den posteriore del av oyet via subkonjunktiv eller periokular levering av et prolegemiddelInfo
- Publication number
- NO20056174L NO20056174L NO20056174A NO20056174A NO20056174L NO 20056174 L NO20056174 L NO 20056174L NO 20056174 A NO20056174 A NO 20056174A NO 20056174 A NO20056174 A NO 20056174A NO 20056174 L NO20056174 L NO 20056174L
- Authority
- NO
- Norway
- Prior art keywords
- delivery
- active drug
- periocular
- prodrug
- posterior portion
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 5
- 239000003814 drug Substances 0.000 title abstract 5
- 229940002612 prodrug Drugs 0.000 title abstract 5
- 239000000651 prodrug Substances 0.000 title abstract 5
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/617,468 US20050009910A1 (en) | 2003-07-10 | 2003-07-10 | Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug |
PCT/US2004/021938 WO2005011741A2 (fr) | 2003-07-10 | 2004-07-07 | Administration d'un medicament actif dans la partie posterieure de l'oeil, via adminstration sous-conjonctivale ou perioculaire d'un promedicament |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20056174L true NO20056174L (no) | 2006-01-25 |
Family
ID=33564972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20056174A NO20056174L (no) | 2003-07-10 | 2005-12-23 | Levering av et aktivt legemiddel til den posteriore del av oyet via subkonjunktiv eller periokular levering av et prolegemiddel |
Country Status (16)
Country | Link |
---|---|
US (2) | US20050009910A1 (fr) |
EP (1) | EP1644047A2 (fr) |
JP (1) | JP2007528851A (fr) |
KR (1) | KR20060033008A (fr) |
CN (1) | CN1882362A (fr) |
AU (1) | AU2004260645B2 (fr) |
BR (1) | BRPI0412496A (fr) |
CA (1) | CA2531753A1 (fr) |
IL (1) | IL172583A (fr) |
MX (1) | MXPA06000408A (fr) |
NO (1) | NO20056174L (fr) |
NZ (2) | NZ582376A (fr) |
PL (1) | PL380169A1 (fr) |
RU (1) | RU2353393C2 (fr) |
WO (1) | WO2005011741A2 (fr) |
ZA (1) | ZA200510129B (fr) |
Families Citing this family (55)
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US20050101582A1 (en) | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
JP2007513161A (ja) * | 2003-12-02 | 2007-05-24 | アラーガン、インコーポレイテッド | レチノイドによる光受容体の変性の予防および/または減少 |
US8871224B2 (en) | 2003-12-09 | 2014-10-28 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
EP1727529B1 (fr) | 2004-03-17 | 2016-03-02 | Lars Michael Larsen | Prevention de la retinopathie par inhibition du cycle visuel |
US20050220734A1 (en) * | 2004-04-02 | 2005-10-06 | Allergan, Inc. | Therapy for melanin related afflictions |
BRPI0510485A (pt) | 2004-04-30 | 2007-11-13 | Allergan Inc | implantes inibidores de tirosina cinase intravìtreos biodegradáveis |
US7771742B2 (en) * | 2004-04-30 | 2010-08-10 | Allergan, Inc. | Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods |
AU2005240078A1 (en) * | 2004-04-30 | 2005-11-17 | Allergan, Inc. | Retinoid-containing sustained release intraocular drug delivery systems and related methods of manufacturing |
AU2011211380B9 (en) * | 2004-04-30 | 2014-05-08 | Allergan, Inc. | Biodegradable intravitreal tyrosine kinase inhibitor implants |
WO2006043965A1 (fr) * | 2004-10-14 | 2006-04-27 | Allergan, Inc. | Compositions ophtalmiques therapeutiques contenant des excipients sans danger pour la retine et leurs methodes |
US8246949B2 (en) * | 2004-10-27 | 2012-08-21 | Aciont, Inc. | Methods and devices for sustained in-vivo release of an active agent |
WO2007130134A2 (fr) * | 2005-12-02 | 2007-11-15 | (Osi) Eyetech, Inc. | Microparticules à libération contrôlée |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
CN101074935B (zh) * | 2006-05-19 | 2011-03-23 | 清华大学 | 探测器阵列及设备 |
PL2322183T3 (pl) * | 2006-06-01 | 2015-01-30 | Santen Sas | Wykorzystanie proleku do podawania doocznego, śródszklistkowego |
MX2011012233A (es) | 2009-05-20 | 2012-04-19 | Ranbaxy Lab Ltd | Soluciones de retinoide topicas. |
US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
CA2791278C (fr) | 2010-02-25 | 2015-11-24 | The Johns Hopkins University | Delivrance prolongee d'agents therapeutiques a un compartiment oculaire |
US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
JP5996544B2 (ja) | 2010-10-15 | 2016-09-21 | クリアサイド・バイオメディカル・インコーポレーテッドClearside Biomedical Incorporated | 眼球アクセス用装置 |
US9327037B2 (en) | 2011-02-08 | 2016-05-03 | The Johns Hopkins University | Mucus penetrating gene carriers |
US9415020B2 (en) | 2012-01-19 | 2016-08-16 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
AU2013232297B2 (en) | 2012-03-16 | 2016-01-14 | The Johns Hopkins University | Controlled release formulations for the delivery of HIF-1 inhibitors |
WO2013138346A1 (fr) | 2012-03-16 | 2013-09-19 | The Johns Hopkins University | Conjugués copolymère multi-blocs non linéaire-médicament pour l'administration de principes actifs |
US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
US10688041B2 (en) | 2012-05-03 | 2020-06-23 | Kala Pharmaceuticals, Inc. | Compositions and methods utilizing poly(vinyl alcohol) and/or other polymers that aid particle transport in mucus |
US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
JP6360039B2 (ja) | 2012-05-03 | 2018-07-18 | カラ ファーマシューティカルズ インコーポレイテッド | 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法 |
EP2849728A1 (fr) | 2012-05-04 | 2015-03-25 | The Johns Hopkins University | Véhicules de médicament à base de lipide pour pénétration rapide à travers les revêtements de mucus |
KR20210133321A (ko) | 2012-11-08 | 2021-11-05 | 클리어사이드 바이오메디컬, 인코포레이드 | 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치 |
WO2014124006A1 (fr) | 2013-02-05 | 2014-08-14 | The Johns Hopkins University | Nanoparticules pour le suivi de l'imagerie par résonance magnétique et procédés de fabrication et d'utilisation associés |
EP4378444A3 (fr) | 2013-05-03 | 2024-07-03 | Clearside Biomedical, Inc. | Appareil et procédés d'injection oculaire |
EP3003454B1 (fr) | 2013-06-03 | 2020-01-08 | Clearside Biomedical, Inc. | Appareil pour une administration de médicament à l'aide de multiples réservoirs |
US10010447B2 (en) | 2013-12-18 | 2018-07-03 | Novartis Ag | Systems and methods for subretinal delivery of therapeutic agents |
WO2015116709A1 (fr) | 2014-01-28 | 2015-08-06 | Allergan, Inc. | Formulations topiques de rétinoïdes, et procédés d'utilisation |
WO2015127389A1 (fr) | 2014-02-23 | 2015-08-27 | The Johns Hopkins University | Formulations de lavement hypotonique et méthodes d'utilisation |
CN106794321A (zh) | 2014-06-20 | 2017-05-31 | 科尼尔赛德生物医学公司 | 可变直径插管以及用于控制对药剂递送的插入深度的方法 |
WO2016123125A1 (fr) | 2015-01-27 | 2016-08-04 | The Johns Hopkins University | Formulations d'hydrogel hypotoniques pour le transport amélioré d'agents actifs au niveau de surfaces muqueuses |
EP3340982B1 (fr) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Composés pour le traitement de troubles immunitaires et inflammatoires |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
EP3413851B1 (fr) | 2016-02-10 | 2023-09-27 | Clearside Biomedical, Inc. | Emballage |
EP3452165A1 (fr) | 2016-05-02 | 2019-03-13 | Clearside Biomedical, Inc. | Systèmes et méthodes pour l'administration de médicaments par voie ophtalmique |
CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
WO2017197036A1 (fr) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Dégronimères spirocycliques pour la dégradation de protéines cibles |
WO2018005552A1 (fr) | 2016-06-27 | 2018-01-04 | Achillion Pharmaceuticals, Inc. | Composés de quinazoline et d'indole destinés au traitement de troubles médicaux |
RU2019102647A (ru) | 2016-07-01 | 2020-08-03 | Г1 Терапьютикс, Инк. | Антипролиферационные средства на основе пиримидина |
IL305537A (en) | 2016-08-12 | 2023-10-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a drug administration needle |
WO2018160889A1 (fr) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceuticals, Inc. | Composés pharmaceutiques aryle, hétéroaryles et hétérocycliques pour le traitement de troubles médicaux |
WO2018204515A1 (fr) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Procédés d'administration ciblée de médicament au moyen d'une microaiguille |
TW201906635A (zh) * | 2017-07-04 | 2019-02-16 | 日商第一三共股份有限公司 | 伴隨視細胞變性的視網膜變性的疾病用藥 |
EP3773576A4 (fr) | 2018-03-26 | 2021-12-29 | C4 Therapeutics, Inc. | Liants de céréblon pour la dégradation d'ikaros |
US20230022157A1 (en) | 2018-08-20 | 2023-01-26 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
JP7504088B2 (ja) | 2018-10-16 | 2024-06-21 | ジョージア ステイト ユニバーシティー リサーチ ファウンデーション インコーポレイテッド | 医学的障害の治療のための一酸化炭素プロドラッグ |
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US5824685A (en) * | 1995-02-01 | 1998-10-20 | The Johns Hopkins University School Of Medicine | Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists |
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US20030018044A1 (en) * | 2000-02-18 | 2003-01-23 | Peyman Gholam A. | Treatment of ocular disease |
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AR030346A1 (es) * | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico |
JP4061015B2 (ja) * | 2000-10-30 | 2008-03-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | レチノイン酸レセプターアゴニスト作用を有する薬剤含有組成物 |
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KR20040005936A (ko) * | 2001-04-26 | 2004-01-16 | 컨트롤 딜리버리 시스템즈 인코포레이티드 | 공동약물을 함유하는 서방 약물 전달 시스템 |
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US7381426B2 (en) * | 2002-01-24 | 2008-06-03 | Southwest Research Institute | Targeted delivery of bioactive factors to the systemic skeleton |
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-
2003
- 2003-07-10 US US10/617,468 patent/US20050009910A1/en not_active Abandoned
-
2004
- 2004-07-07 NZ NZ582376A patent/NZ582376A/en not_active IP Right Cessation
- 2004-07-07 CN CNA2004800195540A patent/CN1882362A/zh active Pending
- 2004-07-07 WO PCT/US2004/021938 patent/WO2005011741A2/fr active Application Filing
- 2004-07-07 BR BRPI0412496-0A patent/BRPI0412496A/pt not_active IP Right Cessation
- 2004-07-07 MX MXPA06000408A patent/MXPA06000408A/es unknown
- 2004-07-07 RU RU2006104983/14A patent/RU2353393C2/ru not_active IP Right Cessation
- 2004-07-07 EP EP04777796A patent/EP1644047A2/fr not_active Withdrawn
- 2004-07-07 NZ NZ544027A patent/NZ544027A/en not_active IP Right Cessation
- 2004-07-07 AU AU2004260645A patent/AU2004260645B2/en not_active Ceased
- 2004-07-07 KR KR1020067000591A patent/KR20060033008A/ko active Search and Examination
- 2004-07-07 PL PL380169A patent/PL380169A1/pl not_active Application Discontinuation
- 2004-07-07 JP JP2006518912A patent/JP2007528851A/ja active Pending
- 2004-07-07 CA CA002531753A patent/CA2531753A1/fr not_active Abandoned
-
2005
- 2005-12-13 ZA ZA200510129A patent/ZA200510129B/en unknown
- 2005-12-14 IL IL172583A patent/IL172583A/en not_active IP Right Cessation
- 2005-12-23 NO NO20056174A patent/NO20056174L/no not_active Application Discontinuation
-
2012
- 2012-02-29 US US13/407,906 patent/US20120157499A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2005011741A2 (fr) | 2005-02-10 |
JP2007528851A (ja) | 2007-10-18 |
CN1882362A (zh) | 2006-12-20 |
RU2006104983A (ru) | 2006-06-27 |
US20120157499A1 (en) | 2012-06-21 |
IL172583A0 (en) | 2006-04-10 |
AU2004260645A1 (en) | 2005-02-10 |
ZA200510129B (en) | 2007-02-28 |
AU2004260645B2 (en) | 2010-03-11 |
CA2531753A1 (fr) | 2005-02-10 |
IL172583A (en) | 2011-02-28 |
RU2353393C2 (ru) | 2009-04-27 |
WO2005011741A3 (fr) | 2005-04-14 |
EP1644047A2 (fr) | 2006-04-12 |
BRPI0412496A (pt) | 2006-09-19 |
US20050009910A1 (en) | 2005-01-13 |
NZ544027A (en) | 2010-07-30 |
KR20060033008A (ko) | 2006-04-18 |
NZ582376A (en) | 2012-02-24 |
PL380169A1 (pl) | 2007-01-08 |
MXPA06000408A (es) | 2006-03-17 |
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