EA200702534A1 - Применение бензоильного производного 3-аминокарбазола для лечения расстройства, связанного с продукцией простагландина e2(pge2) - Google Patents

Применение бензоильного производного 3-аминокарбазола для лечения расстройства, связанного с продукцией простагландина e2(pge2)

Info

Publication number
EA200702534A1
EA200702534A1 EA200702534A EA200702534A EA200702534A1 EA 200702534 A1 EA200702534 A1 EA 200702534A1 EA 200702534 A EA200702534 A EA 200702534A EA 200702534 A EA200702534 A EA 200702534A EA 200702534 A1 EA200702534 A1 EA 200702534A1
Authority
EA
Eurasian Patent Office
Prior art keywords
aminocarbazole
benzoyl derivative
protaglandine
pge2
treatment
Prior art date
Application number
EA200702534A
Other languages
English (en)
Other versions
EA012724B1 (ru
Inventor
Лоренцо Поленцани
Джорджина Мангано
Изабелла Колетта
Мария Алессандра Ализи
Никола Каццолла
Гвидо Фурлотти
Катерина Мауджери
Original Assignee
Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А. filed Critical Ацьенде Кимике Рьюните Анджелини Франческо А.К.Р.А.Ф. С.П.А.
Publication of EA200702534A1 publication Critical patent/EA200702534A1/ru
Publication of EA012724B1 publication Critical patent/EA012724B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Применение бензоильного производного 3-аминокарбазола для получения лекарственного средства для предотвращения или лечения расстройства, выбранного из группы, включающей воспалительные процессы, боль, лихорадку, опухоли, болезнь Альцгеймера и атеросклероз. Способ предотвращения или лечения расстройства, выбранного из группы, включающей воспалительные процессы, боль, лихорадку, опухоли, болезнь Альцгеймера и атеросклероз, в котором вводят индивидууму терапевтически эффективное количество бензоильного производного 3-аминокарбазола, соответствующего этому изобретению.
EA200702534A 2005-05-19 2006-05-03 Применение бензоильного производного 3-аминокарбазола для лечения расстройства, связанного с продукцией простагландина e2 (pge2) EA012724B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000909A ITMI20050909A1 (it) 2005-05-19 2005-05-19 Uso di un benzoil derivato dal 3-ammino-carbazolo per la produzione di un farmaco per il trattamento di un disturbo associato alla produzione di prostaglandina e2-pge2-
PCT/EP2006/004348 WO2006122680A1 (en) 2005-05-19 2006-05-03 Use of a benzoyl derivative of 3-aminocarbazole for the treatment of a disorder associated with the production of prostaglandin e2 (pge2)

Publications (2)

Publication Number Publication Date
EA200702534A1 true EA200702534A1 (ru) 2008-04-28
EA012724B1 EA012724B1 (ru) 2009-12-30

Family

ID=35219704

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702534A EA012724B1 (ru) 2005-05-19 2006-05-03 Применение бензоильного производного 3-аминокарбазола для лечения расстройства, связанного с продукцией простагландина e2 (pge2)

Country Status (24)

Country Link
US (1) US8686021B2 (ru)
EP (1) EP1881826B1 (ru)
JP (1) JP5086991B2 (ru)
KR (1) KR101312579B1 (ru)
CN (1) CN101166528B (ru)
AR (1) AR054126A1 (ru)
AT (1) ATE473739T1 (ru)
AU (1) AU2006246688B2 (ru)
BR (1) BRPI0609718A2 (ru)
CA (1) CA2604562C (ru)
DE (1) DE602006015457D1 (ru)
DK (1) DK1881826T3 (ru)
EA (1) EA012724B1 (ru)
ES (1) ES2347174T3 (ru)
GE (1) GEP20094738B (ru)
HK (1) HK1119571A1 (ru)
IL (1) IL186072A (ru)
IT (1) ITMI20050909A1 (ru)
MX (1) MX2007013491A (ru)
PL (1) PL1881826T3 (ru)
PT (1) PT1881826E (ru)
SI (1) SI1881826T1 (ru)
UA (1) UA94044C2 (ru)
WO (1) WO2006122680A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051523A1 (it) 2005-08-03 2007-02-04 Acraf Composto del 3-ammino-carbazolo composizione farmaceutica che lo contiene e metodo per prepararlo
EP2119705A1 (en) * 2008-05-14 2009-11-18 AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. 3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor
US9313791B2 (en) 2009-05-14 2016-04-12 Qualcomm Incorporated System and method for dropping and adding an air interface in a wireless communication system

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002241368A (ja) * 1997-02-18 2002-08-28 Shionogi & Co Ltd 新規ベンゾラクタム誘導体およびそれを含有する医薬組成物
WO2001007409A1 (en) 1999-07-23 2001-02-01 Astrazeneca Uk Limited Carbazole derivatives and their use as neuropeptide y5 receptor ligands
US6399631B1 (en) * 1999-07-23 2002-06-04 Pfizer Inc. Carbazole neuropeptide Y5 antagonists
WO2001013917A1 (en) * 1999-08-26 2001-03-01 Bristol-Myers Squibb Company Npy antagonists: spiroisoquinolinone derivatives
DE10125961A1 (de) * 2001-05-29 2002-12-12 Boehringer Ingelheim Int Carbazolderivate und deren Verwendung zur Herstellung einer Arzneimittelzusammensetzung zur Behandlung von im Zusammenhang mit NPY stehenden Leiden
CA2403307A1 (en) * 2001-10-23 2003-04-23 Neurogen Corporation Substituted 2-cyclohexyl-4-phenyl-1h-imidazole derivatives
KR20030042344A (ko) * 2001-11-22 2003-05-28 한국생명공학연구원 에레모필란계 화합물 또는 곰취추출물을 유효성분으로함유하는 염증질환 치료제, 면역질환 치료제, 및 암 치료제
ES2193875B2 (es) * 2002-04-09 2005-03-01 Laboratorios Del Dr. Esteve, S.A. Derivados de benzoxazinona, su preparacion y su aplicacion como medicamentos.
KR100402714B1 (ko) * 2002-12-23 2003-11-13 한국생명공학연구원 디테르펜계 화합물을 염증질환, 면역질환 및 암 치료제로사용하는 신규한 용도

Also Published As

Publication number Publication date
CA2604562C (en) 2013-09-17
WO2006122680A1 (en) 2006-11-23
IL186072A0 (en) 2008-08-07
SI1881826T1 (sl) 2010-10-29
CN101166528B (zh) 2011-06-15
CA2604562A1 (en) 2006-11-23
AR054126A1 (es) 2007-06-06
IL186072A (en) 2012-05-31
AU2006246688A1 (en) 2006-11-23
EP1881826B1 (en) 2010-07-14
US20080287518A1 (en) 2008-11-20
DE602006015457D1 (de) 2010-08-26
US8686021B2 (en) 2014-04-01
BRPI0609718A2 (pt) 2011-10-18
EP1881826A1 (en) 2008-01-30
MX2007013491A (es) 2008-01-24
PL1881826T3 (pl) 2010-12-31
CN101166528A (zh) 2008-04-23
ATE473739T1 (de) 2010-07-15
JP5086991B2 (ja) 2012-11-28
UA94044C2 (ru) 2011-04-11
PT1881826E (pt) 2010-08-05
KR20080018898A (ko) 2008-02-28
KR101312579B1 (ko) 2013-09-30
AU2006246688B2 (en) 2011-09-22
GEP20094738B (en) 2009-07-27
HK1119571A1 (ru) 2009-03-13
ES2347174T3 (es) 2010-10-26
DK1881826T3 (da) 2010-11-01
ITMI20050909A1 (it) 2006-11-20
JP2008540591A (ja) 2008-11-20
EA012724B1 (ru) 2009-12-30

Similar Documents

Publication Publication Date Title
EA201071243A1 (ru) Комбинированные композиции для лечения болезни альцгеймера и родственных заболеваний зонизамидом и акампросатом
EA201200686A1 (ru) Новые терапевтические подходы для лечения болезни альцгеймера
EA201791669A3 (ru) Новые терапевтические подходы в лечении смт и связанных с ней расстройств
NO20074999L (no) Metode og preparat for behandling av perifere vaskulaere sykdommer
EA201071245A1 (ru) Новые терапевтические подходы для лечения болезни альцгеймера и связанных нарушений посредством модулирования реакции клеток на стресс
ATE457166T1 (de) Orale zusammensetzungen zur behandlung von diabetes
ATE450269T1 (de) Peptid pyyä3-36ü zur behandlung von stoffwechselkrankheiten
EA201000365A1 (ru) Гетероциклические амиды, пригодные для лечения злокачественного новообразования и псориаза
ATE530544T1 (de) Benzyl-substituierte positive allosterische chinolon-m1-rezeptormodulatoren
TW200800976A (en) New compounds for the treatment of neurological, psychiatric or pain disorders
DK1346041T3 (da) Terapeutiske midler og fremgangsmåder til anvendelse deraf til behandling af en amyloidogen sygdom
DK1970059T3 (da) Lægemiddel med calciumdobesilat til behandling og profylakse af senelidelser
EA200701296A1 (ru) 3,5-дизамещенные и 3,5,7-тризамещенные 3h-оксазоло- и 3h-тиазоло[4,5-d] пиримидин-2-оны и их пролекарства
WO2007100366A3 (en) Quinolone m1 receptor positive allosteric modulators
EA201071244A1 (ru) Новые терапевтические подходы в лечении болезни альцгеймера и обусловленных ею расстройств посредством модуляции ангиогенеза
BRPI0510094A (pt) uso de flibanserina no tratamento pré-menstrual e outros distúrbios sexuais femininos
WO2007127474A3 (en) Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
EA200870254A1 (ru) Способ лечения воспалительных заболеваний
CY1112932T1 (el) Αναστολεις sμαd7 για τη θεραπευτικη αγωγη ασθενειων του κνς
BRPI0508051A (pt) derivados de heteroarilaminopirazol utilizáveis para o tratamento de diabetes
EA200970435A1 (ru) Лечение общих расстройств развития
DK1362039T3 (da) Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin D3-receptorligander
EA200802020A1 (ru) Тетрагидропиримидоазепины и их применение в качестве модуляторов trpv 1
BRPI0507120A (pt) compostos, processo para a manufatura dos mesmos, composições farmacêuticas que os compreendem, método para o tratamento e/ou profilaxia de enfermidades que estão associadas com a modulação de receptores de cb1 e sua utilização
ATE390928T1 (de) Zusammensetzungen zur behandlung von hauterkrankungen

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU