NO20055848L - Nye spacer-enheter for poly(etylenglykol)-modifiserte peptidbaserte forbindelser - Google Patents
Nye spacer-enheter for poly(etylenglykol)-modifiserte peptidbaserte forbindelserInfo
- Publication number
- NO20055848L NO20055848L NO20055848A NO20055848A NO20055848L NO 20055848 L NO20055848 L NO 20055848L NO 20055848 A NO20055848 A NO 20055848A NO 20055848 A NO20055848 A NO 20055848A NO 20055848 L NO20055848 L NO 20055848L
- Authority
- NO
- Norway
- Prior art keywords
- unit
- poly
- ethylene glycol
- based compounds
- modified peptide
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyamides (AREA)
Abstract
Den forehggende oppfinnelsen vedrører en forbindelse som omfatter en peptidenhet, en spacerenhet og en vannløselig polymerenhet slik som en poly(etylenglykol)enhet. Spacerenheten er mellom peptidenheten og den vannløselige polymerenheten. Spacerenheten har strukturen: -NH-(CH2)¿-[0-(CH2)p],-05-(CH2).-Y- hvor a, p, y, 8 og s er hver hele tall hvis verdi er uavhengig valgt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46999603P | 2003-05-12 | 2003-05-12 | |
PCT/US2004/014887 WO2004100997A2 (en) | 2003-05-12 | 2004-05-12 | Spacer moiety for poly(ethylene glycol) -modified peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20055848L true NO20055848L (no) | 2006-02-13 |
Family
ID=33452348
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20055848A NO20055848L (no) | 2003-05-12 | 2005-12-09 | Nye spacer-enheter for poly(etylenglykol)-modifiserte peptidbaserte forbindelser |
Country Status (16)
Country | Link |
---|---|
US (2) | US7919118B2 (no) |
EP (2) | EP1628686A2 (no) |
JP (2) | JP2007500218A (no) |
KR (1) | KR101160611B1 (no) |
CN (1) | CN1849141A (no) |
AU (1) | AU2004238364A1 (no) |
BR (1) | BRPI0411166A (no) |
CA (1) | CA2525399A1 (no) |
EA (1) | EA010015B1 (no) |
IL (1) | IL171885A0 (no) |
IS (1) | IS8168A (no) |
MX (1) | MXPA05012314A (no) |
NO (1) | NO20055848L (no) |
NZ (2) | NZ543934A (no) |
WO (1) | WO2004100997A2 (no) |
ZA (1) | ZA200509970B (no) |
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EP1628686A2 (en) | 2003-05-12 | 2006-03-01 | Affymax, Inc. | Spacer moiety for poly (ethylene glycol)-modified peptides |
UA88146C2 (ru) * | 2003-05-12 | 2009-09-25 | Афимакс, Инк. | Новые пептиды, которые связываются с рецептором эритропоэтина |
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US7807171B2 (en) | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
US20080026995A1 (en) * | 2003-07-25 | 2008-01-31 | Ac Immune Sa | Therapeutic vaccine targeted against p-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
EP1687024B1 (en) * | 2003-11-05 | 2011-10-19 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Carbohydrate antigen-nanoparticle conjugates and uses thereof as antimetastatic agents in treating cancer |
US7589063B2 (en) | 2004-12-14 | 2009-09-15 | Aplagen Gmbh | Molecules which promote hematopoiesis |
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EP2590666B1 (en) | 2010-07-06 | 2017-04-26 | Augustinus Bader | Topical application of erythropoietin for use in the treatment of injuries of the cornea |
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EP3310376A4 (en) * | 2015-06-17 | 2019-01-23 | The California Institute for Biomedical Research | MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF |
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-
2004
- 2004-05-12 EP EP04760996A patent/EP1628686A2/en not_active Ceased
- 2004-05-12 KR KR1020057021599A patent/KR101160611B1/ko not_active IP Right Cessation
- 2004-05-12 CA CA002525399A patent/CA2525399A1/en not_active Abandoned
- 2004-05-12 EA EA200501800A patent/EA010015B1/ru not_active IP Right Cessation
- 2004-05-12 JP JP2006532998A patent/JP2007500218A/ja active Pending
- 2004-05-12 US US10/555,860 patent/US7919118B2/en not_active Expired - Fee Related
- 2004-05-12 NZ NZ543934A patent/NZ543934A/en not_active IP Right Cessation
- 2004-05-12 NZ NZ563042A patent/NZ563042A/en not_active IP Right Cessation
- 2004-05-12 BR BRPI0411166-4A patent/BRPI0411166A/pt not_active IP Right Cessation
- 2004-05-12 AU AU2004238364A patent/AU2004238364A1/en not_active Abandoned
- 2004-05-12 EP EP10160196A patent/EP2204193A3/en not_active Withdrawn
- 2004-05-12 WO PCT/US2004/014887 patent/WO2004100997A2/en active Application Filing
- 2004-05-12 CN CNA2004800187597A patent/CN1849141A/zh active Pending
- 2004-05-12 MX MXPA05012314A patent/MXPA05012314A/es active IP Right Grant
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2005
- 2005-11-10 IL IL171885A patent/IL171885A0/en unknown
- 2005-12-02 IS IS8168A patent/IS8168A/is unknown
- 2005-12-08 ZA ZA200509970A patent/ZA200509970B/en unknown
- 2005-12-09 NO NO20055848A patent/NO20055848L/no not_active Application Discontinuation
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2011
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Also Published As
Publication number | Publication date |
---|---|
CN1849141A (zh) | 2006-10-18 |
EA010015B1 (ru) | 2008-06-30 |
JP2007500218A (ja) | 2007-01-11 |
EA200501800A1 (ru) | 2006-08-25 |
KR20060023123A (ko) | 2006-03-13 |
US8592365B2 (en) | 2013-11-26 |
AU2004238364A1 (en) | 2004-11-25 |
MXPA05012314A (es) | 2006-04-18 |
US20070032408A1 (en) | 2007-02-08 |
EP2204193A2 (en) | 2010-07-07 |
JP2012140466A (ja) | 2012-07-26 |
IS8168A (is) | 2005-12-02 |
EP1628686A2 (en) | 2006-03-01 |
NZ543934A (en) | 2008-06-30 |
US20120115796A1 (en) | 2012-05-10 |
KR101160611B1 (ko) | 2012-06-28 |
CA2525399A1 (en) | 2004-11-25 |
ZA200509970B (en) | 2006-11-29 |
WO2004100997A2 (en) | 2004-11-25 |
EP2204193A3 (en) | 2010-08-18 |
BRPI0411166A (pt) | 2006-07-18 |
WO2004100997A3 (en) | 2005-05-19 |
NZ563042A (en) | 2008-09-26 |
US7919118B2 (en) | 2011-04-05 |
IL171885A0 (en) | 2006-04-10 |
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