IS8168A - Rýmishelft fyrir fjöl(etýlenglýkól) breytt peptíð - Google Patents

Rýmishelft fyrir fjöl(etýlenglýkól) breytt peptíð

Info

Publication number
IS8168A
IS8168A IS8168A IS8168A IS8168A IS 8168 A IS8168 A IS 8168A IS 8168 A IS8168 A IS 8168A IS 8168 A IS8168 A IS 8168A IS 8168 A IS8168 A IS 8168A
Authority
IS
Iceland
Prior art keywords
poly
ethylene glycol
modified peptide
space half
space
Prior art date
Application number
IS8168A
Other languages
English (en)
Inventor
P. Holmes Christopher
Tumelty David
Yin Qun
Original Assignee
Affymax, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymax, Inc. filed Critical Affymax, Inc.
Publication of IS8168A publication Critical patent/IS8168A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
IS8168A 2003-05-12 2005-12-02 Rýmishelft fyrir fjöl(etýlenglýkól) breytt peptíð IS8168A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46999603P 2003-05-12 2003-05-12
PCT/US2004/014887 WO2004100997A2 (en) 2003-05-12 2004-05-12 Spacer moiety for poly(ethylene glycol) -modified peptides

Publications (1)

Publication Number Publication Date
IS8168A true IS8168A (is) 2005-12-02

Family

ID=33452348

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8168A IS8168A (is) 2003-05-12 2005-12-02 Rýmishelft fyrir fjöl(etýlenglýkól) breytt peptíð

Country Status (16)

Country Link
US (2) US7919118B2 (is)
EP (2) EP2204193A3 (is)
JP (2) JP2007500218A (is)
KR (1) KR101160611B1 (is)
CN (1) CN1849141A (is)
AU (1) AU2004238364A1 (is)
BR (1) BRPI0411166A (is)
CA (1) CA2525399A1 (is)
EA (1) EA010015B1 (is)
IL (1) IL171885A0 (is)
IS (1) IS8168A (is)
MX (1) MXPA05012314A (is)
NO (1) NO20055848L (is)
NZ (2) NZ543934A (is)
WO (1) WO2004100997A2 (is)
ZA (1) ZA200509970B (is)

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NZ544024A (en) * 2003-05-12 2009-06-26 Affymax Inc Novel poly(ethylene glycol) modified compounds and uses thereof
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DK1629007T3 (da) 2003-05-12 2009-06-29 Affymax Inc Hidtil ukendte peptider som binder til erythropoietin-receptoren
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
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US20080026995A1 (en) * 2003-07-25 2008-01-31 Ac Immune Sa Therapeutic vaccine targeted against p-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
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WO2004100997A2 (en) 2004-11-25
KR20060023123A (ko) 2006-03-13
EP2204193A2 (en) 2010-07-07
JP2012140466A (ja) 2012-07-26
NO20055848L (no) 2006-02-13
EP1628686A2 (en) 2006-03-01
KR101160611B1 (ko) 2012-06-28
ZA200509970B (en) 2006-11-29
US20070032408A1 (en) 2007-02-08
EP2204193A3 (en) 2010-08-18
EA200501800A1 (ru) 2006-08-25
US20120115796A1 (en) 2012-05-10
CA2525399A1 (en) 2004-11-25
BRPI0411166A (pt) 2006-07-18
IL171885A0 (en) 2006-04-10
US8592365B2 (en) 2013-11-26
MXPA05012314A (es) 2006-04-18
WO2004100997A3 (en) 2005-05-19
CN1849141A (zh) 2006-10-18
NZ543934A (en) 2008-06-30
AU2004238364A1 (en) 2004-11-25
JP2007500218A (ja) 2007-01-11
EA010015B1 (ru) 2008-06-30
NZ563042A (en) 2008-09-26
US7919118B2 (en) 2011-04-05

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