DK1628989T3 - Hidtil ukendte, 14- og 15-leddet ring-forbindelser - Google Patents

Hidtil ukendte, 14- og 15-leddet ring-forbindelser

Info

Publication number
DK1628989T3
DK1628989T3 DK04732108T DK04732108T DK1628989T3 DK 1628989 T3 DK1628989 T3 DK 1628989T3 DK 04732108 T DK04732108 T DK 04732108T DK 04732108 T DK04732108 T DK 04732108T DK 1628989 T3 DK1628989 T3 DK 1628989T3
Authority
DK
Denmark
Prior art keywords
new
membered ring
ring connections
connections
membered
Prior art date
Application number
DK04732108T
Other languages
English (en)
Inventor
Sulejman Alihodzic
John Michael Berge
Richard Lewis Jarvest
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0310962A external-priority patent/GB0310962D0/en
Priority claimed from GB0407391A external-priority patent/GB0407391D0/en
Application filed by Glaxo Group Ltd, Glaxosmithkline Zagreb filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK1628989T3 publication Critical patent/DK1628989T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK04732108T 2003-05-13 2004-05-11 Hidtil ukendte, 14- og 15-leddet ring-forbindelser DK1628989T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0310962A GB0310962D0 (en) 2003-05-13 2003-05-13 Novel compounds
GB0407391A GB0407391D0 (en) 2004-03-31 2004-03-31 Novel compounds
PCT/EP2004/005083 WO2004101587A1 (en) 2003-05-13 2004-05-11 Novel 14 and 15 memberred-ring compounds

Publications (1)

Publication Number Publication Date
DK1628989T3 true DK1628989T3 (da) 2007-10-08

Family

ID=33454579

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04732108T DK1628989T3 (da) 2003-05-13 2004-05-11 Hidtil ukendte, 14- og 15-leddet ring-forbindelser

Country Status (15)

Country Link
US (1) US20070293472A1 (da)
EP (1) EP1628989B1 (da)
JP (1) JP2006528667A (da)
AR (1) AR044304A1 (da)
AT (1) ATE348837T1 (da)
CA (1) CA2525455A1 (da)
CL (1) CL2004001012A1 (da)
DE (1) DE602004003809T2 (da)
DK (1) DK1628989T3 (da)
ES (1) ES2278319T3 (da)
HR (1) HRP20070094T3 (da)
PL (1) PL1628989T3 (da)
PT (1) PT1628989E (da)
SI (1) SI1628989T1 (da)
WO (1) WO2004101587A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2772254A3 (en) 2003-03-10 2015-03-11 Optimer Pharmaceuticals, Inc. Novel Antibacterial Agents
WO2005108412A1 (en) * 2004-05-06 2005-11-17 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ester linked macrolides useful for the treatment of microbial infections
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
EP1945652A1 (en) * 2005-11-09 2008-07-23 Glaxo Group Limited Macrolones
EP1951735A1 (en) * 2005-11-09 2008-08-06 Glaxo Group Limited New 4*-substituted erythromycin derivative
JP5698979B2 (ja) 2007-10-25 2015-04-08 センプラ ファーマシューティカルズ,インコーポレイテッド マクロライド系抗菌剤の調製プロセス
CN105616437A (zh) 2008-10-24 2016-06-01 森普拉制药公司 使用含三唑的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN108310000A (zh) 2009-09-10 2018-07-24 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
DK2571506T3 (da) 2010-05-20 2017-08-28 Cempra Pharmaceuticals Inc Fremgangsmåder til fremstilling af makrolider og ketolider og mellemprodukter dertil
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
RU2658050C2 (ru) 2012-03-27 2018-06-19 Семпра Фармасьютикалз, Инк. Парентеральные составы для введения макролидных антибиотиков
JP6426696B2 (ja) 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ,インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
CA2907085A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US4686207A (en) * 1985-11-12 1987-08-11 Abbott Laboratories Erythromycin A 11,12-carbonates and method of use
EP0465581B1 (en) * 1989-03-28 1995-10-04 Abbott Laboratories Erythromycin derivatives
AU3710695A (en) * 1995-04-27 1996-11-18 Laboratorios Aranda, S.A. De C.V. Quinolonylcarboxyerythromycin derivatives and pharmaceutical compositions containing them
CZ349698A3 (cs) * 1996-05-07 1999-04-14 Abbott Laboratories 3-deskladinoso-2,3-anhydroerythromycinové deriváty
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
WO2003014136A1 (en) * 2001-08-08 2003-02-20 Taisho Pharmaceutical Co., Ltd. 11a-AZALIDE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
DE602004003809T2 (de) 2007-10-11
PT1628989E (pt) 2007-03-30
JP2006528667A (ja) 2006-12-21
WO2004101587A1 (en) 2004-11-25
DE602004003809D1 (de) 2007-02-01
AR044304A1 (es) 2005-09-07
EP1628989A1 (en) 2006-03-01
CL2004001012A1 (es) 2005-03-18
ES2278319T3 (es) 2007-08-01
SI1628989T1 (sl) 2007-06-30
PL1628989T3 (pl) 2007-05-31
HRP20070094T3 (en) 2008-05-31
US20070293472A1 (en) 2007-12-20
CA2525455A1 (en) 2004-11-25
EP1628989B1 (en) 2006-12-20
ATE348837T1 (de) 2007-01-15

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