NO20045071L - Fremgangsmate for fremstilling av krystaller ut i fra aktive legemiddelvirkestoffer, krystaller oppnadd derav og deres anvendelse i farmasoytiske formuleringer - Google Patents
Fremgangsmate for fremstilling av krystaller ut i fra aktive legemiddelvirkestoffer, krystaller oppnadd derav og deres anvendelse i farmasoytiske formuleringerInfo
- Publication number
- NO20045071L NO20045071L NO20045071A NO20045071A NO20045071L NO 20045071 L NO20045071 L NO 20045071L NO 20045071 A NO20045071 A NO 20045071A NO 20045071 A NO20045071 A NO 20045071A NO 20045071 L NO20045071 L NO 20045071L
- Authority
- NO
- Norway
- Prior art keywords
- crystals
- pharmaceutical formulations
- preparation
- obtained therefrom
- active ingredients
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Det beskrives en fremgangsmåte for fremstilling av krystaller av legemiddelaktivbestanddel hvis gjennomsnittlige partikkelstørrelse ligger innen et på forhånd gitt område og hvis maksimale partikkelstørrelse ikke overskrider en på forhånd gitt verdi, hvorved en overmettet oppløsning under krystalliseringen underkastes en våtoppmaling ved hjelp av en innretning for våtoppmaling, hvorved det oppnås en primærkornsuspensjon.Det beskrives videre de krystaller som oppnås ved denne metode samt farmasøytiske formuleringer inneholdende krystallene.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10218106A DE10218106A1 (de) | 2002-04-23 | 2002-04-23 | Verfahren zum Herstellen von Kristallen von Arzneimittelwirkstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen |
PCT/EP2003/004153 WO2003090721A2 (de) | 2002-04-23 | 2003-04-22 | Verfahren zur herstellung von kristallen von arzneimittelwirkstoffen und deren verwendung in pharmazeutischen formulierungen |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20045071L true NO20045071L (no) | 2005-01-21 |
Family
ID=29264786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20045071A NO20045071L (no) | 2002-04-23 | 2004-11-22 | Fremgangsmate for fremstilling av krystaller ut i fra aktive legemiddelvirkestoffer, krystaller oppnadd derav og deres anvendelse i farmasoytiske formuleringer |
Country Status (16)
Country | Link |
---|---|
US (1) | US20030215516A1 (no) |
EP (1) | EP1523302A2 (no) |
JP (1) | JP2005535577A (no) |
KR (1) | KR20050003388A (no) |
CN (1) | CN1812767A (no) |
AU (1) | AU2003232490A1 (no) |
BR (1) | BR0309358A (no) |
CA (1) | CA2480130A1 (no) |
DE (1) | DE10218106A1 (no) |
IL (1) | IL163984A0 (no) |
MX (1) | MXPA04010466A (no) |
NO (1) | NO20045071L (no) |
PL (1) | PL371518A1 (no) |
RU (1) | RU2004134321A (no) |
WO (1) | WO2003090721A2 (no) |
ZA (1) | ZA200409398B (no) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI365068B (en) * | 2005-05-20 | 2012-06-01 | Merck Sharp & Dohme | Formulations of suberoylanilide hydroxamic acid and methods for producing same |
BRPI0708470A2 (pt) * | 2006-03-14 | 2011-05-31 | Merck & Co Inc | processo para a produção de partìculas cristalinas de um composto ativo orgánico, e, composição farmacêutica |
DE102010003711B4 (de) * | 2010-04-08 | 2015-04-09 | Jesalis Pharma Gmbh | Verfahren zur Herstellung kristalliner Wirkstoffpartikel |
US9745250B2 (en) | 2014-05-13 | 2017-08-29 | Akzo Nobel Chemicals International B.V. | Process to crystallize chelating agents |
CN108031142A (zh) * | 2017-12-13 | 2018-05-15 | 上海合全药物研发有限公司 | 一种简化的利用湿磨来制备大量微晶种的装置及方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB838654A (en) * | 1956-02-08 | 1960-06-22 | Upjohn Co | Steroids and the production thereof |
US3226389A (en) * | 1962-01-04 | 1965-12-28 | Du Pont | 11,11,12,12-tetracyano-naphtho-2,6-quinodimethan and its anion-radical salts |
CH627449A5 (de) * | 1977-03-25 | 1982-01-15 | Hoffmann La Roche | Verfahren zur herstellung von mikrokristallinem vitamin a-acetat, sowie von trockenen, frei-fliessenden praeparaten, in welchen vitamin a-acetat in mikrokristalliner form vorliegt. |
DE2801705A1 (de) * | 1978-01-16 | 1979-07-19 | Metallgesellschaft Ag | Verfahren zur gewinnung von kaliumchlorid |
DE3014160A1 (de) * | 1979-04-16 | 1980-10-30 | Lummus Co | Kristallisationsverfahren |
DE3306250A1 (de) * | 1983-02-23 | 1984-08-23 | Basf Ag, 6700 Ludwigshafen | Sphaerische einkristalle fuer pharmazeutische zwecke |
US4997637A (en) * | 1989-05-09 | 1991-03-05 | Occidental Chemical Corporation | Digestive crystallizing process and apparatus for purification of KC1 |
FR2668945B1 (fr) * | 1990-11-12 | 1993-02-19 | Theramex | Nouveau procede de cristallisation des substances organiques et les composes ainsi obtenus. |
DE4143631A1 (de) * | 1991-05-30 | 1998-04-16 | Dynamit Nobel Ag | Zerkleinerung von pulverförmigen Initialsprengstoffen |
DE4244466C2 (de) * | 1992-12-24 | 1995-02-23 | Pharmatech Gmbh | Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten |
-
2002
- 2002-04-23 DE DE10218106A patent/DE10218106A1/de not_active Ceased
-
2003
- 2003-04-17 US US10/417,556 patent/US20030215516A1/en not_active Abandoned
- 2003-04-22 AU AU2003232490A patent/AU2003232490A1/en not_active Abandoned
- 2003-04-22 RU RU2004134321/15A patent/RU2004134321A/ru not_active Application Discontinuation
- 2003-04-22 CA CA002480130A patent/CA2480130A1/en not_active Abandoned
- 2003-04-22 KR KR10-2004-7017080A patent/KR20050003388A/ko not_active Application Discontinuation
- 2003-04-22 IL IL16398403A patent/IL163984A0/xx unknown
- 2003-04-22 EP EP03747106A patent/EP1523302A2/de not_active Withdrawn
- 2003-04-22 JP JP2003587358A patent/JP2005535577A/ja not_active Withdrawn
- 2003-04-22 PL PL03371518A patent/PL371518A1/xx not_active Application Discontinuation
- 2003-04-22 WO PCT/EP2003/004153 patent/WO2003090721A2/de active Application Filing
- 2003-04-22 BR BR0309358-1A patent/BR0309358A/pt not_active IP Right Cessation
- 2003-04-22 CN CNA038092123A patent/CN1812767A/zh active Pending
- 2003-04-22 MX MXPA04010466A patent/MXPA04010466A/es unknown
-
2004
- 2004-11-22 ZA ZA200409398A patent/ZA200409398B/en unknown
- 2004-11-22 NO NO20045071A patent/NO20045071L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2480130A1 (en) | 2003-11-06 |
KR20050003388A (ko) | 2005-01-10 |
DE10218106A1 (de) | 2003-11-20 |
IL163984A0 (en) | 2005-12-18 |
PL371518A1 (en) | 2005-06-27 |
CN1812767A (zh) | 2006-08-02 |
RU2004134321A (ru) | 2005-10-10 |
EP1523302A2 (de) | 2005-04-20 |
WO2003090721A2 (de) | 2003-11-06 |
US20030215516A1 (en) | 2003-11-20 |
BR0309358A (pt) | 2005-02-22 |
ZA200409398B (en) | 2006-06-28 |
WO2003090721A3 (de) | 2005-02-24 |
JP2005535577A (ja) | 2005-11-24 |
MXPA04010466A (es) | 2004-12-13 |
AU2003232490A1 (en) | 2003-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |