MD2447G2 - Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei - Google Patents

Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei Download PDF

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Publication number
MD2447G2
MD2447G2 MDA20020139A MD20020139A MD2447G2 MD 2447 G2 MD2447 G2 MD 2447G2 MD A20020139 A MDA20020139 A MD A20020139A MD 20020139 A MD20020139 A MD 20020139A MD 2447 G2 MD2447 G2 MD 2447G2
Authority
MD
Moldova
Prior art keywords
sickness
vomiting
treatment
cephalalgia
migraine
Prior art date
Application number
MDA20020139A
Other languages
English (en)
Russian (ru)
Other versions
MD2447F2 (ro
MD20020139A (ro
Inventor
Александр МИРИМСКИ
Рафаэль Баркан
Original Assignee
Meditor Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL14463201A external-priority patent/IL144632A0/xx
Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd
Publication of MD20020139A publication Critical patent/MD20020139A/ro
Publication of MD2447F2 publication Critical patent/MD2447F2/ro
Publication of MD2447G2 publication Critical patent/MD2447G2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Invenţia se referă la derivaţii S-alchilisotiouroniului, care pot fi utilizaţi pentru tratamentul cefaleei, migrenei, greţurilor şi vomei.Se propune o compoziţie farmaceutică, care conţine, în calitate de ingredient activ, compusul cu formula:(radicalii sunt menţionaţi în descriere); utilizarea compoziţiei farmaceutice pentru prepararea medicamentelor şi metode de tratare a cefaleei, migrenei, greţurilor şi vomei şi de prevenire a greţurilor şi vomei la tratamentul anticanceros cu chimioterapie sau radioterapie.
MDA20020139A 2000-09-05 2001-08-30 Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei MD2447G2 (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22981200P 2000-09-05 2000-09-05
IL14463201A IL144632A0 (en) 2001-07-30 2001-07-30 Method and pharmaceutical compositions for treating headache, nausea and migraine
PCT/IL2001/000817 WO2002019961A2 (en) 2000-09-05 2001-08-30 Pharmaceutical compositions for headache, migraine, nausea and emesis

Publications (3)

Publication Number Publication Date
MD20020139A MD20020139A (ro) 2002-11-30
MD2447F2 MD2447F2 (ro) 2004-05-31
MD2447G2 true MD2447G2 (ro) 2005-12-31

Family

ID=26324036

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20020139A MD2447G2 (ro) 2000-09-05 2001-08-30 Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei

Country Status (21)

Country Link
US (2) US7148208B2 (ro)
EP (1) EP1315505B1 (ro)
JP (1) JP2004508311A (ro)
KR (1) KR100849999B1 (ro)
CN (1) CN100448439C (ro)
AT (1) ATE375797T1 (ro)
AU (2) AU8617801A (ro)
BR (1) BR0113698A (ro)
CA (1) CA2420410C (ro)
CY (1) CY1107270T1 (ro)
DE (1) DE60131004T2 (ro)
DK (1) DK1315505T3 (ro)
ES (1) ES2296792T3 (ro)
HU (1) HUP0302362A3 (ro)
IL (1) IL154456A (ro)
MD (1) MD2447G2 (ro)
MX (1) MXPA03001737A (ro)
NO (1) NO20031902L (ro)
NZ (1) NZ524903A (ro)
PT (1) PT1315505E (ro)
WO (1) WO2002019961A2 (ro)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1315505T3 (da) * 2000-09-05 2008-03-03 Meditor Pharmaceuticals Ltd Farmaceutiske præparater mod hovedpine, migræne, kvalme og emesis
US20090186854A1 (en) * 2006-03-23 2009-07-23 Meditor Pharmaceuticals Ltd. S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
EA200901591A1 (ru) * 2007-06-13 2010-06-30 Медитор Фармасьютикалс Лтд. Фармацевтические композиции производных s-алкилизотиоурония с маскированным вкусом
RU2342923C1 (ru) * 2007-07-26 2009-01-10 Общество с ограниченной ответственностью "Бентус лаборатории" Дезинфицирующее антисептическое средство для обработки рук с увлажняющим эффектом (варианты)
EP2219447B1 (en) * 2007-11-06 2013-07-03 Barkan-Farma S.r.l. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
MD3619G2 (ro) * 2007-11-06 2009-01-31 Рафаэль Баркан Remediu medicamentos nazal cu acţiune anticongestivă
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
US9560967B2 (en) 2008-04-24 2017-02-07 The Invention Science Fund I Llc Systems and apparatus for measuring a bioactive agent effect
US20100063368A1 (en) * 2008-04-24 2010-03-11 Searete Llc, A Limited Liability Corporation Computational system and method for memory modification
US9239906B2 (en) 2008-04-24 2016-01-19 The Invention Science Fund I, Llc Combination treatment selection methods and systems
US8876688B2 (en) 2008-04-24 2014-11-04 The Invention Science Fund I, Llc Combination treatment modification methods and systems
US20100130811A1 (en) * 2008-04-24 2010-05-27 Searete Llc Computational system and method for memory modification
US8682687B2 (en) 2008-04-24 2014-03-25 The Invention Science Fund I, Llc Methods and systems for presenting a combination treatment
US8615407B2 (en) 2008-04-24 2013-12-24 The Invention Science Fund I, Llc Methods and systems for detecting a bioactive agent effect
US9064036B2 (en) 2008-04-24 2015-06-23 The Invention Science Fund I, Llc Methods and systems for monitoring bioactive agent use
US8606592B2 (en) 2008-04-24 2013-12-10 The Invention Science Fund I, Llc Methods and systems for monitoring bioactive agent use
US20090270687A1 (en) * 2008-04-24 2009-10-29 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for modifying bioactive agent use
US9282927B2 (en) 2008-04-24 2016-03-15 Invention Science Fund I, Llc Methods and systems for modifying bioactive agent use
US8930208B2 (en) 2008-04-24 2015-01-06 The Invention Science Fund I, Llc Methods and systems for detecting a bioactive agent effect
US9649469B2 (en) 2008-04-24 2017-05-16 The Invention Science Fund I Llc Methods and systems for presenting a combination treatment
US9449150B2 (en) 2008-04-24 2016-09-20 The Invention Science Fund I, Llc Combination treatment selection methods and systems
US20100069724A1 (en) * 2008-04-24 2010-03-18 Searete Llc Computational system and method for memory modification
US7974787B2 (en) * 2008-04-24 2011-07-05 The Invention Science Fund I, Llc Combination treatment alteration methods and systems
US9662391B2 (en) 2008-04-24 2017-05-30 The Invention Science Fund I Llc Side effect ameliorating combination therapeutic products and systems
US9026369B2 (en) 2008-04-24 2015-05-05 The Invention Science Fund I, Llc Methods and systems for presenting a combination treatment
US8357117B2 (en) * 2008-08-06 2013-01-22 Family Health International Device and method for delivering an agent into breast milk while breastfeeding
WO2012018341A1 (en) * 2010-08-05 2012-02-09 Family Health International Device and method for delivering an agent into breast milk while breastfeeding
CN109523244B (zh) * 2018-11-02 2023-06-27 创新先进技术有限公司 一种基于母子账户的用于转移款项数据的方法和系统

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD263B1 (ro) * 1995-03-01 1995-08-31 Victor GHICAVII Remediu cu actiune antihipotensiva "izoturon"
MD586B1 (ro) * 1995-05-25 1996-07-31 Univ Nicolae Testemitanu Substanta medicamentoasa cu actiune antihipotensiva "Difetur"
WO1998013036A1 (en) * 1996-09-26 1998-04-02 Meditor Pharmaceuticals Ltd. Pharmaceutical compositions comprising s-alkylisothiouronium derivatives
MD1138B1 (ro) * 1997-02-17 1999-01-31 Univ Nicolae Testemitanu Izopropilfosfit-S-izopropilizotiuroniu - substanta cu actiune hipertensiva
MD1223B1 (ro) * 1997-07-15 1999-05-31 Univ Nicolae Testemitanu Aplicarea dimetilfosfatului de S-metil-izo-tiouroniu in calitate de substanta vaso-con-strictoare si preparat farmaceutic pe baza lui
MD1431F1 (ro) * 1998-01-16 2000-03-31 Univ Nicolae Testemitanu Remedii antihipotensive

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FR2419675A1 (fr) * 1978-03-16 1979-10-12 Philagro Sa Compositions fongicides a base de phosphites d'isothiouronium
GB9418912D0 (en) * 1994-09-20 1994-11-09 Fisons Corp Pharmaceutically active compounds
FR2753098B1 (fr) * 1996-09-06 1998-11-27 Sod Conseils Rech Applic Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene
AU734490B2 (en) * 1996-11-05 2001-06-14 Neuraxon Inc. A method for treating tension-type headache
US6127420A (en) * 1997-08-22 2000-10-03 The Medical College Of Wisconsin Research Foundation, Inc. L-N5 -(1-imino-3-alkenyl) ornithine and related compounds and use thereof
US6093743A (en) * 1998-06-23 2000-07-25 Medinox Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
FR2788771B1 (fr) * 1999-01-22 2001-04-13 Pf Medicament Nouvelles 1,2-alcoyl-1-[1-[aryl (alcoyl) oxyalcoyl] piperidin-4-yl]-3-aryl isothiourees substituees, leur preparation et leur application en therapeutique
AU3511500A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
EP1200127B1 (en) * 1999-07-21 2008-06-25 Omeros Corporation Solutions and methods for inhibition of pain, inflammation and cartilage degradation
DK1315505T3 (da) * 2000-09-05 2008-03-03 Meditor Pharmaceuticals Ltd Farmaceutiske præparater mod hovedpine, migræne, kvalme og emesis

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD263B1 (ro) * 1995-03-01 1995-08-31 Victor GHICAVII Remediu cu actiune antihipotensiva "izoturon"
MD586B1 (ro) * 1995-05-25 1996-07-31 Univ Nicolae Testemitanu Substanta medicamentoasa cu actiune antihipotensiva "Difetur"
WO1998013036A1 (en) * 1996-09-26 1998-04-02 Meditor Pharmaceuticals Ltd. Pharmaceutical compositions comprising s-alkylisothiouronium derivatives
MD1138B1 (ro) * 1997-02-17 1999-01-31 Univ Nicolae Testemitanu Izopropilfosfit-S-izopropilizotiuroniu - substanta cu actiune hipertensiva
MD1223B1 (ro) * 1997-07-15 1999-05-31 Univ Nicolae Testemitanu Aplicarea dimetilfosfatului de S-metil-izo-tiouroniu in calitate de substanta vaso-con-strictoare si preparat farmaceutic pe baza lui
MD1431F1 (ro) * 1998-01-16 2000-03-31 Univ Nicolae Testemitanu Remedii antihipotensive

Also Published As

Publication number Publication date
NZ524903A (en) 2004-11-26
HUP0302362A3 (en) 2005-05-30
EP1315505A2 (en) 2003-06-04
US20070088005A1 (en) 2007-04-19
US8673979B2 (en) 2014-03-18
CY1107270T1 (el) 2012-11-21
NO20031902L (no) 2003-06-09
CN1464788A (zh) 2003-12-31
DE60131004D1 (de) 2007-11-29
HK1058009A1 (zh) 2004-04-30
WO2002019961A3 (en) 2002-08-15
KR20030055257A (ko) 2003-07-02
BR0113698A (pt) 2003-12-09
CA2420410A1 (en) 2002-03-14
DE60131004T2 (de) 2008-07-31
IL154456A (en) 2013-05-30
ES2296792T3 (es) 2008-05-01
JP2004508311A (ja) 2004-03-18
MD2447F2 (ro) 2004-05-31
MD20020139A (ro) 2002-11-30
MXPA03001737A (es) 2004-09-10
US20040006044A1 (en) 2004-01-08
KR100849999B1 (ko) 2008-08-01
AU8617801A (en) 2002-03-22
CN100448439C (zh) 2009-01-07
NO20031902D0 (no) 2003-04-28
CA2420410C (en) 2011-04-26
HUP0302362A2 (hu) 2003-11-28
AU2001286178B2 (en) 2006-09-14
PT1315505E (pt) 2008-01-28
WO2002019961A2 (en) 2002-03-14
ATE375797T1 (de) 2007-11-15
US7148208B2 (en) 2006-12-12
EP1315505B1 (en) 2007-10-17
EP1315505A4 (en) 2006-02-22
DK1315505T3 (da) 2008-03-03

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Legal Events

Date Code Title Description
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees