MD2447G2 - Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei - Google Patents

Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei

Info

Publication number
MD2447G2
MD2447G2 MDA20020139A MD20020139A MD2447G2 MD 2447 G2 MD2447 G2 MD 2447G2 MD A20020139 A MDA20020139 A MD A20020139A MD 20020139 A MD20020139 A MD 20020139A MD 2447 G2 MD2447 G2 MD 2447G2
Authority
MD
Moldova
Prior art keywords
sickness
vomiting
treatment
cephalalgia
migraine
Prior art date
Application number
MDA20020139A
Other languages
English (en)
Russian (ru)
Other versions
MD20020139A (ro
MD2447F2 (ro
Inventor
Александр МИРИМСКИ
Рафаэль Баркан
Original Assignee
Meditor Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL14463201A external-priority patent/IL144632A0/xx
Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd
Publication of MD20020139A publication Critical patent/MD20020139A/ro
Publication of MD2447F2 publication Critical patent/MD2447F2/ro
Publication of MD2447G2 publication Critical patent/MD2447G2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Invenţia se referă la derivaţii S-alchilisotiouroniului, care pot fi utilizaţi pentru tratamentul cefaleei, migrenei, greţurilor şi vomei.Se propune o compoziţie farmaceutică, care conţine, în calitate de ingredient activ, compusul cu formula:(radicalii sunt menţionaţi în descriere); utilizarea compoziţiei farmaceutice pentru prepararea medicamentelor şi metode de tratare a cefaleei, migrenei, greţurilor şi vomei şi de prevenire a greţurilor şi vomei la tratamentul anticanceros cu chimioterapie sau radioterapie.
MDA20020139A 2000-09-05 2001-08-30 Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei MD2447G2 (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22981200P 2000-09-05 2000-09-05
IL14463201A IL144632A0 (en) 2001-07-30 2001-07-30 Method and pharmaceutical compositions for treating headache, nausea and migraine
PCT/IL2001/000817 WO2002019961A2 (en) 2000-09-05 2001-08-30 Pharmaceutical compositions for headache, migraine, nausea and emesis

Publications (3)

Publication Number Publication Date
MD20020139A MD20020139A (ro) 2002-11-30
MD2447F2 MD2447F2 (ro) 2004-05-31
MD2447G2 true MD2447G2 (ro) 2005-12-31

Family

ID=26324036

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20020139A MD2447G2 (ro) 2000-09-05 2001-08-30 Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei

Country Status (22)

Country Link
US (2) US7148208B2 (ro)
EP (1) EP1315505B1 (ro)
JP (1) JP2004508311A (ro)
KR (1) KR100849999B1 (ro)
CN (1) CN100448439C (ro)
AT (1) ATE375797T1 (ro)
AU (2) AU2001286178B2 (ro)
BR (1) BR0113698A (ro)
CA (1) CA2420410C (ro)
CY (1) CY1107270T1 (ro)
DE (1) DE60131004T2 (ro)
DK (1) DK1315505T3 (ro)
ES (1) ES2296792T3 (ro)
HK (1) HK1058009A1 (ro)
HU (1) HUP0302362A3 (ro)
IL (1) IL154456A (ro)
MD (1) MD2447G2 (ro)
MX (1) MXPA03001737A (ro)
NO (1) NO20031902L (ro)
NZ (1) NZ524903A (ro)
PT (1) PT1315505E (ro)
WO (1) WO2002019961A2 (ro)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100448439C (zh) * 2000-09-05 2009-01-07 麦迪特制药有限公司 用于头痛、偏头痛、恶心和呕吐的药物组合物
US20090186854A1 (en) * 2006-03-23 2009-07-23 Meditor Pharmaceuticals Ltd. S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
EA200901591A1 (ru) * 2007-06-13 2010-06-30 Медитор Фармасьютикалс Лтд. Фармацевтические композиции производных s-алкилизотиоурония с маскированным вкусом
MD3619G2 (ro) * 2007-11-06 2009-01-31 Рафаэль Баркан Remediu medicamentos nazal cu acţiune anticongestivă
EP2219447B1 (en) * 2007-11-06 2013-07-03 Barkan-Farma S.r.l. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
US9649469B2 (en) 2008-04-24 2017-05-16 The Invention Science Fund I Llc Methods and systems for presenting a combination treatment
US8876688B2 (en) 2008-04-24 2014-11-04 The Invention Science Fund I, Llc Combination treatment modification methods and systems
US8606592B2 (en) 2008-04-24 2013-12-10 The Invention Science Fund I, Llc Methods and systems for monitoring bioactive agent use
US8615407B2 (en) 2008-04-24 2013-12-24 The Invention Science Fund I, Llc Methods and systems for detecting a bioactive agent effect
US20100130811A1 (en) * 2008-04-24 2010-05-27 Searete Llc Computational system and method for memory modification
US20100063368A1 (en) * 2008-04-24 2010-03-11 Searete Llc, A Limited Liability Corporation Computational system and method for memory modification
US9282927B2 (en) 2008-04-24 2016-03-15 Invention Science Fund I, Llc Methods and systems for modifying bioactive agent use
US9662391B2 (en) 2008-04-24 2017-05-30 The Invention Science Fund I Llc Side effect ameliorating combination therapeutic products and systems
US20100069724A1 (en) * 2008-04-24 2010-03-18 Searete Llc Computational system and method for memory modification
US20090270687A1 (en) * 2008-04-24 2009-10-29 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for modifying bioactive agent use
US7974787B2 (en) * 2008-04-24 2011-07-05 The Invention Science Fund I, Llc Combination treatment alteration methods and systems
US9560967B2 (en) 2008-04-24 2017-02-07 The Invention Science Fund I Llc Systems and apparatus for measuring a bioactive agent effect
US8682687B2 (en) 2008-04-24 2014-03-25 The Invention Science Fund I, Llc Methods and systems for presenting a combination treatment
US8930208B2 (en) 2008-04-24 2015-01-06 The Invention Science Fund I, Llc Methods and systems for detecting a bioactive agent effect
US9064036B2 (en) 2008-04-24 2015-06-23 The Invention Science Fund I, Llc Methods and systems for monitoring bioactive agent use
US9449150B2 (en) 2008-04-24 2016-09-20 The Invention Science Fund I, Llc Combination treatment selection methods and systems
US9026369B2 (en) 2008-04-24 2015-05-05 The Invention Science Fund I, Llc Methods and systems for presenting a combination treatment
US9239906B2 (en) 2008-04-24 2016-01-19 The Invention Science Fund I, Llc Combination treatment selection methods and systems
US8357117B2 (en) * 2008-08-06 2013-01-22 Family Health International Device and method for delivering an agent into breast milk while breastfeeding
WO2012018341A1 (en) * 2010-08-05 2012-02-09 Family Health International Device and method for delivering an agent into breast milk while breastfeeding
CN109523244B (zh) * 2018-11-02 2023-06-27 创新先进技术有限公司 一种基于母子账户的用于转移款项数据的方法和系统

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD263B1 (ro) * 1995-03-01 1995-08-31 Victor GHICAVII Remediu cu actiune antihipotensiva "izoturon"
MD586B1 (ro) * 1995-05-25 1996-07-31 Univ Nicolae Testemitanu Substanta medicamentoasa cu actiune antihipotensiva "Difetur"
WO1998013036A1 (en) * 1996-09-26 1998-04-02 Meditor Pharmaceuticals Ltd. Pharmaceutical compositions comprising s-alkylisothiouronium derivatives
MD1138B1 (ro) * 1997-02-17 1999-01-31 Univ Nicolae Testemitanu Izopropilfosfit-S-izopropilizotiuroniu - substanta cu actiune hipertensiva
MD1223B1 (ro) * 1997-07-15 1999-05-31 Univ Nicolae Testemitanu Aplicarea dimetilfosfatului de S-metil-izo-tiouroniu in calitate de substanta vaso-con-strictoare si preparat farmaceutic pe baza lui
MD1431F1 (ro) * 1998-01-16 2000-03-31 Univ Nicolae Testemitanu Remedii antihipotensive

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2419675A1 (fr) * 1978-03-16 1979-10-12 Philagro Sa Compositions fongicides a base de phosphites d'isothiouronium
GB9418912D0 (en) * 1994-09-20 1994-11-09 Fisons Corp Pharmaceutically active compounds
FR2753098B1 (fr) * 1996-09-06 1998-11-27 Sod Conseils Rech Applic Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene
WO1998019674A2 (en) * 1996-11-05 1998-05-14 Head Explorer Aps A method for treating tension-type headache
US6127420A (en) * 1997-08-22 2000-10-03 The Medical College Of Wisconsin Research Foundation, Inc. L-N5 -(1-imino-3-alkenyl) ornithine and related compounds and use thereof
US6093743A (en) * 1998-06-23 2000-07-25 Medinox Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
FR2788771B1 (fr) * 1999-01-22 2001-04-13 Pf Medicament Nouvelles 1,2-alcoyl-1-[1-[aryl (alcoyl) oxyalcoyl] piperidin-4-yl]-3-aryl isothiourees substituees, leur preparation et leur application en therapeutique
WO2000051623A2 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
CA2378880C (en) * 1999-07-21 2010-02-23 Omeros Medical Systems, Inc. Solutions and methods for inhibition of pain, inflammation and cartilage degradation
CN100448439C (zh) * 2000-09-05 2009-01-07 麦迪特制药有限公司 用于头痛、偏头痛、恶心和呕吐的药物组合物

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD263B1 (ro) * 1995-03-01 1995-08-31 Victor GHICAVII Remediu cu actiune antihipotensiva "izoturon"
MD586B1 (ro) * 1995-05-25 1996-07-31 Univ Nicolae Testemitanu Substanta medicamentoasa cu actiune antihipotensiva "Difetur"
WO1998013036A1 (en) * 1996-09-26 1998-04-02 Meditor Pharmaceuticals Ltd. Pharmaceutical compositions comprising s-alkylisothiouronium derivatives
MD1138B1 (ro) * 1997-02-17 1999-01-31 Univ Nicolae Testemitanu Izopropilfosfit-S-izopropilizotiuroniu - substanta cu actiune hipertensiva
MD1223B1 (ro) * 1997-07-15 1999-05-31 Univ Nicolae Testemitanu Aplicarea dimetilfosfatului de S-metil-izo-tiouroniu in calitate de substanta vaso-con-strictoare si preparat farmaceutic pe baza lui
MD1431F1 (ro) * 1998-01-16 2000-03-31 Univ Nicolae Testemitanu Remedii antihipotensive

Also Published As

Publication number Publication date
IL154456A (en) 2013-05-30
CY1107270T1 (el) 2012-11-21
KR100849999B1 (ko) 2008-08-01
MXPA03001737A (es) 2004-09-10
CN100448439C (zh) 2009-01-07
JP2004508311A (ja) 2004-03-18
ES2296792T3 (es) 2008-05-01
HUP0302362A2 (hu) 2003-11-28
NO20031902L (no) 2003-06-09
AU2001286178B2 (en) 2006-09-14
MD20020139A (ro) 2002-11-30
DE60131004D1 (de) 2007-11-29
DK1315505T3 (da) 2008-03-03
DE60131004T2 (de) 2008-07-31
EP1315505A2 (en) 2003-06-04
HK1058009A1 (en) 2004-04-30
US7148208B2 (en) 2006-12-12
BR0113698A (pt) 2003-12-09
NO20031902D0 (no) 2003-04-28
US8673979B2 (en) 2014-03-18
EP1315505A4 (en) 2006-02-22
PT1315505E (pt) 2008-01-28
ATE375797T1 (de) 2007-11-15
NZ524903A (en) 2004-11-26
US20040006044A1 (en) 2004-01-08
WO2002019961A3 (en) 2002-08-15
MD2447F2 (ro) 2004-05-31
EP1315505B1 (en) 2007-10-17
CA2420410A1 (en) 2002-03-14
KR20030055257A (ko) 2003-07-02
CA2420410C (en) 2011-04-26
US20070088005A1 (en) 2007-04-19
HUP0302362A3 (en) 2005-05-30
CN1464788A (zh) 2003-12-31
AU8617801A (en) 2002-03-22
WO2002019961A2 (en) 2002-03-14

Similar Documents

Publication Publication Date Title
MD2447G2 (ro) Compoziţie farmaceutică, utilizarea ei şi metodă de tratare a cefaleei, migrenei, greţurilor şi vomei
JO2339B1 (en) Benzamidazole compounds
UA90858C2 (ru) Композиция с контролируемым высвобождением варденафила
AP1739A (en) Azaindoles
TW200500358A (en) Compounds
WO2004004632A3 (en) Flavone derivatives as inhibitors of cyclin-dependent kinases
HK1091481A1 (en) Therapeutic agents useful for treating pain
WO2006034341A3 (en) Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
TW200626139A (en) Heterocyclic derivatives and their use as therapeutic agents
TW200626572A (en) Heterocyclic derivatives and their use as therapeutic agents
UA84266C2 (uk) Дозована лікарська форма у вигляді таблетки або пелети для перорального введення, яка містить інгібітор pde 4 та полівінілпіролідон, способи її одержання та застосування
TW200626592A (en) Heterocyclic derivatives and their use as therapeutic agents
MY141661A (en) 17b-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
UA85708C2 (ru) Лекарственные комбинации, содержащие бензоксазины, для лечения заболеваний дыхательных путей
TW200624427A (en) Heterocyclic derivatives and their use as therapeutic agents
GB0114286D0 (en) Nucleoside Derivatives
SG147450A1 (en) Sustained release pharmaceutical compositions comprising aplindore and derivatives thereof
TNSN04203A1 (en) Benzoxazinone-derived compounds, their preparation and use as medicaments
MY128014A (en) Thiol and thiocarbonyl derivatives which are useful as carboxypeptidase u inhibitors
UA86776C2 (ru) Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и применение
EA200000355A2 (ru) Промышленные изделия
TW200504029A (en) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
MXPA05013050A (es) Derivados de bencimidazol, composiciones que los contienen preparacion de los mismos y usos de los mismos.
TW200509992A (en) Dosage form containing pantoprazole as active ingredient
HK1075390A1 (en) Citalopram for the treatment of elevated blood pressure

Legal Events

Date Code Title Description
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees