MXPA05011076A - Derivados de quinazolina para el tratamiento de cancer. - Google Patents

Derivados de quinazolina para el tratamiento de cancer.

Info

Publication number
MXPA05011076A
MXPA05011076A MXPA05011076A MXPA05011076A MXPA05011076A MX PA05011076 A MXPA05011076 A MX PA05011076A MX PA05011076 A MXPA05011076 A MX PA05011076A MX PA05011076 A MXPA05011076 A MX PA05011076A MX PA05011076 A MXPA05011076 A MX PA05011076A
Authority
MX
Mexico
Prior art keywords
chemical compounds
preparation
treatment
proliferative diseases
medicaments
Prior art date
Application number
MXPA05011076A
Other languages
English (en)
Inventor
Georges Rene Pasquet
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of MXPA05011076A publication Critical patent/MXPA05011076A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Derivados de quinazolina de la formula (I); para su uso en el tratamiento de enfermedades proliferantes tales como cancer y en la preparacion de medicamentos para su uso en el tratamiento de enfermedades proliferantes y al proceso para su preparacion, asi como composiciones farmaceuticas que los contienen como ingredientes activos.
MXPA05011076A 2003-04-16 2004-04-14 Derivados de quinazolina para el tratamiento de cancer. MXPA05011076A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03290951 2003-04-16
PCT/GB2004/001614 WO2004094410A1 (en) 2003-04-16 2004-04-14 Chemical compounds

Publications (1)

Publication Number Publication Date
MXPA05011076A true MXPA05011076A (es) 2006-01-24

Family

ID=33305809

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05011076A MXPA05011076A (es) 2003-04-16 2004-04-14 Derivados de quinazolina para el tratamiento de cancer.

Country Status (23)

Country Link
US (1) US7691867B2 (es)
EP (1) EP1613619B1 (es)
JP (1) JP4709139B2 (es)
KR (1) KR20060003351A (es)
CN (1) CN1809557B (es)
AR (1) AR043875A1 (es)
AT (1) ATE390422T1 (es)
AU (1) AU2004232527A1 (es)
BR (1) BRPI0409427A (es)
CA (1) CA2522079A1 (es)
CL (1) CL2004000797A1 (es)
CO (1) CO5640037A2 (es)
DE (1) DE602004012725T2 (es)
ES (1) ES2301981T3 (es)
HK (1) HK1086573A1 (es)
IS (1) IS8125A (es)
MX (1) MXPA05011076A (es)
NO (1) NO20054842L (es)
RU (1) RU2005135337A (es)
TW (1) TW200510392A (es)
UY (1) UY28271A1 (es)
WO (1) WO2004094410A1 (es)
ZA (1) ZA200508372B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU229477B1 (en) * 2001-12-24 2014-01-28 Astrazeneca Ab Substituted quinazoline derivatives as inhibitors of aurora kinases
NZ540698A (en) * 2002-12-24 2008-05-30 Astrazeneca Ab Phosphonooxy quinazoline derivatives and their pharmaceutical use
JP2006526599A (ja) * 2003-06-02 2006-11-24 アストラゼネカ アクチボラグ 癌のような増殖性疾患の治療のためのオーロラキナーゼインヒビターとしての（３−（（キナゾリン−４−イル）アミノ）−１ｈ−ピラゾール−１−イル）アセトアミド誘導体及び関連化合物
EP1746999B1 (en) 2004-05-06 2011-11-16 Warner-Lambert Company LLC 4-phenylamino-quinazolin-6-yl-amides
EP1802603A1 (en) * 2004-10-12 2007-07-04 AstraZeneca AB Quinoline derivatives
US20090036474A1 (en) * 2004-10-12 2009-02-05 Patrick Ple Quinazoline derivatives for use against cancer
ATE540935T1 (de) 2004-10-12 2012-01-15 Astrazeneca Ab Chinazolinderivate
US7713973B2 (en) 2004-10-15 2010-05-11 Takeda Pharmaceutical Company Limited Kinase inhibitors
BRPI0517734A (pt) 2004-11-17 2008-10-21 Korea Res Inst Chem Tech derivados de 1-[(6,7-alcoxiquinoxalinil substituìdo) aminocarbonil]-4- (hetero) arilpiperazina
JP2008542345A (ja) * 2005-05-28 2008-11-27 アストラゼネカ アクチボラグ キナゾリン類及びオーロラキナーゼ阻害剤としてのその使用
GB0510963D0 (en) * 2005-05-28 2005-07-06 Astrazeneca Ab Chemical compounds
EP1931639A2 (en) * 2005-09-22 2008-06-18 Astra Zeneca AB Process
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
GB0601215D0 (en) * 2006-01-21 2006-03-01 Astrazeneca Ab Chemical compounds
UY30183A1 (es) 2006-03-02 2007-10-31 Astrazeneca Ab Derivados de quinolina
WO2007099317A1 (en) * 2006-03-02 2007-09-07 Astrazeneca Ab Quinazoline derivatives
WO2007113565A1 (en) * 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives as anti-cancer agents
GB0609617D0 (en) 2006-05-16 2006-06-21 Astrazeneca Ab Process & intermediate
JP2010505962A (ja) 2006-10-09 2010-02-25 武田薬品工業株式会社 キナーゼ阻害剤
FR2908409B1 (fr) * 2006-11-10 2009-01-09 Sanofi Aventis Sa Pyrazoles substituees,compositions les contenant,procede de fabrication et utilisation
TWI577671B (zh) * 2011-11-14 2017-04-11 Sunshine Lake Pharma Co Ltd Aminoquinazoline derivatives and salts thereof and methods of use thereof
CN103012428A (zh) * 2013-01-08 2013-04-03 中国药科大学 4-(五元杂环并嘧啶/吡啶取代)氨基-1H-3-吡唑甲酰胺类CDK/Aurora双重抑制剂及其用途
CN104098551B (zh) * 2013-04-03 2019-03-22 广东东阳光药业有限公司 作为欧若拉激酶抑制剂的取代喹唑啉类衍生物
CN103382158B (zh) * 2013-07-29 2015-11-18 张家港市大伟助剂有限公司 一种2-环戊基氨基乙醇的制备方法
EP3046917B1 (en) 2013-09-19 2017-11-08 Pierre Fabre Medicament Quinazoline derivatives and their use as dna methyltransferase inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5710158A (en) * 1991-05-10 1998-01-20 Rhone-Poulenc Rorer Pharmaceuticals Inc. Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
TW321649B (es) * 1994-11-12 1997-12-01 Zeneca Ltd
WO1997017329A1 (fr) * 1995-11-07 1997-05-15 Kirin Beer Kabushiki Kaisha Derives de quinoline et derives de quinazoline inhibant l'autophosphorylation d'un recepteur de facteur de croissance originaire de plaquettes, et compositions pharmaceutiques les contenant
RU2002110461A (ru) * 1999-09-21 2004-03-10 Астразенека Аб (Se) Производные хиназолина и их применение в качестве фармацевтических веществ
GB9922171D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Chemical compounds
SK18102002A3 (sk) * 2000-06-28 2003-07-01 Astrazeneca Ab Substituované chinazolínové deriváty, ich použitie a kompozícia obsahujúca tieto deriváty
HU229477B1 (en) 2001-12-24 2014-01-28 Astrazeneca Ab Substituted quinazoline derivatives as inhibitors of aurora kinases
AU2003257666A1 (en) * 2002-08-23 2004-03-11 Kirin Beer Kabushiki Kaisha COMPOUND HAVING TGFss INHIBITORY ACTIVITY AND MEDICINAL COMPOSITION CONTAINING THE SAME
US20060058325A1 (en) 2002-12-24 2006-03-16 Astrazeneca Ab Therapeutic quniazoline derivatives
NZ540698A (en) * 2002-12-24 2008-05-30 Astrazeneca Ab Phosphonooxy quinazoline derivatives and their pharmaceutical use
KR20050087863A (ko) * 2002-12-24 2005-08-31 아스트라제네카 아베 퀴나졸린 화합물
JP2006526599A (ja) * 2003-06-02 2006-11-24 アストラゼネカ アクチボラグ 癌のような増殖性疾患の治療のためのオーロラキナーゼインヒビターとしての（３−（（キナゾリン−４−イル）アミノ）−１ｈ−ピラゾール−１−イル）アセトアミド誘導体及び関連化合物
TW200505452A (en) * 2003-06-17 2005-02-16 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
JP4709139B2 (ja) 2011-06-22
ES2301981T3 (es) 2008-07-01
JP2006523660A (ja) 2006-10-19
UY28271A1 (es) 2004-11-30
RU2005135337A (ru) 2006-06-10
EP1613619B1 (en) 2008-03-26
DE602004012725T2 (de) 2009-04-16
TW200510392A (en) 2005-03-16
IS8125A (is) 2005-11-11
ZA200508372B (en) 2007-04-25
CL2004000797A1 (es) 2005-05-27
WO2004094410A1 (en) 2004-11-04
US7691867B2 (en) 2010-04-06
NO20054842L (no) 2005-11-08
CA2522079A1 (en) 2004-11-04
US20060270692A1 (en) 2006-11-30
HK1086573A1 (en) 2006-09-22
CO5640037A2 (es) 2006-05-31
AR043875A1 (es) 2005-08-17
AU2004232527A1 (en) 2004-11-04
ATE390422T1 (de) 2008-04-15
CN1809557A (zh) 2006-07-26
BRPI0409427A (pt) 2006-04-18
EP1613619A1 (en) 2006-01-11
CN1809557B (zh) 2012-07-04
KR20060003351A (ko) 2006-01-10
DE602004012725D1 (de) 2008-05-08

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