NO20042185L - Kromatografisk rensing av rekombinant humant erytropoietin - Google Patents
Kromatografisk rensing av rekombinant humant erytropoietinInfo
- Publication number
- NO20042185L NO20042185L NO20042185A NO20042185A NO20042185L NO 20042185 L NO20042185 L NO 20042185L NO 20042185 A NO20042185 A NO 20042185A NO 20042185 A NO20042185 A NO 20042185A NO 20042185 L NO20042185 L NO 20042185L
- Authority
- NO
- Norway
- Prior art keywords
- recombinant human
- chromatographic purification
- human erythropoietin
- erythropoietin
- chromatographic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33383901P | 2001-11-28 | 2001-11-28 | |
PCT/EP2002/013299 WO2003045996A1 (en) | 2001-11-28 | 2002-11-26 | Chromatographic purification of recombinant human erythropoietin |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20042185L true NO20042185L (no) | 2004-08-23 |
Family
ID=23304479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20042185A NO20042185L (no) | 2001-11-28 | 2004-05-26 | Kromatografisk rensing av rekombinant humant erytropoietin |
Country Status (20)
Country | Link |
---|---|
US (1) | US20060099674A1 (es) |
EP (1) | EP1453857B1 (es) |
JP (1) | JP4293908B2 (es) |
KR (1) | KR20040065567A (es) |
CN (1) | CN1596268A (es) |
AU (1) | AU2002356733A1 (es) |
BR (1) | BR0214568A (es) |
CA (1) | CA2466627A1 (es) |
ES (1) | ES2525945T3 (es) |
HR (1) | HRP20040476A2 (es) |
HU (1) | HUP0500061A2 (es) |
IL (1) | IL161855A0 (es) |
MX (1) | MXPA04005189A (es) |
NO (1) | NO20042185L (es) |
NZ (1) | NZ533083A (es) |
PL (1) | PL368755A1 (es) |
RU (1) | RU2004119818A (es) |
SI (1) | SI1453857T1 (es) |
WO (1) | WO2003045996A1 (es) |
ZA (1) | ZA200403461B (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003080852A1 (en) * | 2002-03-26 | 2003-10-02 | Lek Pharmaceutical And Chemical Company D.D. | Process for the preparation of a desired erythropoietin glyco-isoform profile |
ES2312523T3 (es) * | 2002-12-13 | 2009-03-01 | Bioceuticals Arzneimittel Ag | Procedimiento para la produccion y purificacion de eritropoyetina. |
US7157276B2 (en) * | 2003-06-20 | 2007-01-02 | Biogen Idec Inc. | Use of depth filtration in series with continuous centrifugation to clarify mammalian cell cultures |
KR100567448B1 (ko) * | 2003-11-05 | 2006-04-04 | 주식회사 인투젠 | 형질전환 동물의 유즙 전처리방법 및 이를 통한 인체단백질의 정제방법 |
DE102004027816A1 (de) * | 2004-06-08 | 2006-01-05 | Bioceuticals Arzneimittel Ag | Verfahren zur Reinigung von Erythropoietin |
JP4742042B2 (ja) * | 2004-06-30 | 2011-08-10 | テルモ株式会社 | ウィルス不活化ヘモグロビンおよびその製造方法 |
US7531632B2 (en) * | 2006-02-16 | 2009-05-12 | Gtc Biotherapeutics, Inc. | Clarification of transgenic milk using depth filtration |
KR100988706B1 (ko) * | 2007-03-07 | 2010-10-18 | 한미홀딩스 주식회사 | 재조합 에리트로포이에틴의 신규한 정제방법 |
KR100900033B1 (ko) * | 2007-11-21 | 2009-06-01 | 한국생명공학연구원 | 인간 에리스로포이에틴의 정제방법 |
DE102008002209A1 (de) | 2008-06-04 | 2009-12-10 | Evonik Degussa Gmbh | Verfahren zur Aufreinigung von Erythropoietin |
RU2011102447A (ru) | 2008-06-24 | 2012-07-27 | Др.Реддис' Лабораторис Лтд. (In) | Очистка модифицированных цитокинов |
CN102203113A (zh) * | 2008-10-17 | 2011-09-28 | 佩尔希维亚有限责任公司 | 澄清方法 |
DE102008054716A1 (de) | 2008-12-16 | 2010-06-17 | Evonik Degussa Gmbh | Inprozesskontrolle in einem Verfahren zur Herstellung von EPO |
US20120264688A1 (en) * | 2009-09-23 | 2012-10-18 | Walter Hinderer | Process for the purification of recombinant human erythropoietin (epo), epo thus purified and pharmaceutical compositions comprising same |
WO2011063195A2 (en) * | 2009-11-20 | 2011-05-26 | Dr. Reddy's Laboratories Ltd. | Purification of modified cytokines |
CN102453087B (zh) * | 2010-10-22 | 2013-12-25 | 广东赛保尔生物医药技术有限公司 | 一种单取代peg-epo的纯化及制备方法 |
US20130331554A1 (en) * | 2010-11-15 | 2013-12-12 | Biogen Idec Inc. | Enrichment and concentration of select product isoforms by overloaded bind and elute chromatography |
WO2012069474A2 (en) * | 2010-11-24 | 2012-05-31 | H. Lundbeck A/S | A method for reducing potential virus burden in a sample by cyanate treatment |
KR101443257B1 (ko) | 2011-10-18 | 2014-09-19 | 주식회사 종근당 | 낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법 |
US10066001B2 (en) * | 2013-03-15 | 2018-09-04 | Apotex Inc. | Enhanced liquid formulation stability of erythropoietin alpha through purification processing |
JP2016532100A (ja) | 2013-07-05 | 2016-10-13 | ラボラトワール・フランセ・デュ・フラクシオンマン・エ・デ・ビョテクノロジーLaboratoire Francais Du Fractionnement Et Des Biotechnologies | アフィニティークロマトグラフィーマトリックス |
KR101414897B1 (ko) | 2013-11-29 | 2014-07-04 | 씨제이헬스케어 주식회사 | 다베포에틴 알파의 정제 방법 |
WO2015134640A1 (en) * | 2014-03-05 | 2015-09-11 | GlycoScientific LLC | Isotopically labeled glycans and methods for producing the same |
SG11201704822WA (en) | 2014-12-15 | 2017-07-28 | Merck Patent Gmbh | Target molecule capture from crude solutions |
EP3153522A1 (en) | 2015-10-09 | 2017-04-12 | Hetero Drugs Limited | Process for the purification of erythropoietin and darbepoetin alfa |
CN106770597A (zh) * | 2017-03-01 | 2017-05-31 | 上海博威生物医药有限公司 | 用于检测组合物中促红细胞生成素电荷异质体的cze检测方法 |
CN112940101A (zh) * | 2019-12-11 | 2021-06-11 | 深圳赛保尔生物药业有限公司 | 重组人促红细胞生成素的纯化方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4677195A (en) * | 1985-01-11 | 1987-06-30 | Genetics Institute, Inc. | Method for the purification of erythropoietin and erythropoietin compositions |
US5856298A (en) * | 1989-10-13 | 1999-01-05 | Amgen Inc. | Erythropoietin isoforms |
DE69130990T2 (de) | 1990-02-20 | 1999-12-02 | Baxter Int | Gereinigtes, virusfreies menschliches Thrombin |
DE19504211A1 (de) * | 1995-02-09 | 1996-08-14 | Behringwerke Ag | Entfernen von Viren durch Ultrafiltration aus Proteinlösungen |
TW442492B (en) | 1995-07-26 | 2001-06-23 | Novartis Ag | Process for the enrichment of interferon |
US6150133A (en) * | 1996-03-13 | 2000-11-21 | Delta Biotechnology Limited | Fermentation control |
BR9917606A (pt) | 1998-11-06 | 2002-12-31 | Bio Sidus S A | Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento |
-
2002
- 2002-11-26 SI SI200231050T patent/SI1453857T1/sl unknown
- 2002-11-26 PL PL02368755A patent/PL368755A1/xx unknown
- 2002-11-26 NZ NZ533083A patent/NZ533083A/en unknown
- 2002-11-26 JP JP2003547445A patent/JP4293908B2/ja not_active Expired - Lifetime
- 2002-11-26 KR KR10-2004-7008088A patent/KR20040065567A/ko not_active Application Discontinuation
- 2002-11-26 EP EP02803796.8A patent/EP1453857B1/en not_active Expired - Lifetime
- 2002-11-26 US US10/494,558 patent/US20060099674A1/en not_active Abandoned
- 2002-11-26 WO PCT/EP2002/013299 patent/WO2003045996A1/en active Application Filing
- 2002-11-26 CN CNA028236017A patent/CN1596268A/zh active Pending
- 2002-11-26 IL IL16185502A patent/IL161855A0/xx unknown
- 2002-11-26 ES ES02803796.8T patent/ES2525945T3/es not_active Expired - Lifetime
- 2002-11-26 RU RU2004119818/04A patent/RU2004119818A/ru not_active Application Discontinuation
- 2002-11-26 BR BR0214568-5A patent/BR0214568A/pt not_active IP Right Cessation
- 2002-11-26 MX MXPA04005189A patent/MXPA04005189A/es not_active Application Discontinuation
- 2002-11-26 CA CA002466627A patent/CA2466627A1/en not_active Abandoned
- 2002-11-26 HU HU0500061A patent/HUP0500061A2/hu unknown
- 2002-11-26 AU AU2002356733A patent/AU2002356733A1/en not_active Abandoned
-
2004
- 2004-05-06 ZA ZA200403461A patent/ZA200403461B/en unknown
- 2004-05-26 NO NO20042185A patent/NO20042185L/no not_active Application Discontinuation
- 2004-05-27 HR HR20040476A patent/HRP20040476A2/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA200403461B (en) | 2006-05-31 |
ES2525945T3 (es) | 2015-01-02 |
CN1596268A (zh) | 2005-03-16 |
RU2004119818A (ru) | 2006-01-10 |
JP2005518196A (ja) | 2005-06-23 |
HRP20040476A2 (en) | 2005-10-31 |
AU2002356733A1 (en) | 2003-06-10 |
KR20040065567A (ko) | 2004-07-22 |
CA2466627A1 (en) | 2003-06-05 |
EP1453857A1 (en) | 2004-09-08 |
MXPA04005189A (es) | 2005-02-17 |
WO2003045996A1 (en) | 2003-06-05 |
BR0214568A (pt) | 2004-11-03 |
EP1453857B1 (en) | 2014-08-13 |
IL161855A0 (en) | 2005-11-20 |
SI1453857T1 (sl) | 2015-01-30 |
PL368755A1 (en) | 2005-04-04 |
US20060099674A1 (en) | 2006-05-11 |
NZ533083A (en) | 2006-09-29 |
JP4293908B2 (ja) | 2009-07-08 |
HUP0500061A2 (hu) | 2005-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |