NO20041379L - Enzymatiske prosesser for fremstilling av 4-substituerte 3-hydroksysmorsyrederivater - Google Patents

Enzymatiske prosesser for fremstilling av 4-substituerte 3-hydroksysmorsyrederivater

Info

Publication number
NO20041379L
NO20041379L NO20041379A NO20041379A NO20041379L NO 20041379 L NO20041379 L NO 20041379L NO 20041379 A NO20041379 A NO 20041379A NO 20041379 A NO20041379 A NO 20041379A NO 20041379 L NO20041379 L NO 20041379L
Authority
NO
Norway
Prior art keywords
acid derivatives
hydroxybutyric acid
substituted
preparation
enzymatic processes
Prior art date
Application number
NO20041379A
Other languages
English (en)
Norwegian (no)
Inventor
Christopher S Davis
John H Grate
David R Gray
John M Gruber
Gjalr W Huisman
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of NO20041379L publication Critical patent/NO20041379L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
NO20041379A 2002-08-09 2004-04-02 Enzymatiske prosesser for fremstilling av 4-substituerte 3-hydroksysmorsyrederivater NO20041379L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40243602P 2002-08-09 2002-08-09
US10/639,159 US7125693B2 (en) 2002-08-09 2003-08-11 Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
PCT/US2003/025263 WO2004015132A2 (en) 2002-08-09 2003-08-11 Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives

Publications (1)

Publication Number Publication Date
NO20041379L true NO20041379L (no) 2004-06-01

Family

ID=31715856

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20041379A NO20041379L (no) 2002-08-09 2004-04-02 Enzymatiske prosesser for fremstilling av 4-substituerte 3-hydroksysmorsyrederivater

Country Status (12)

Country Link
US (1) US7125693B2 (de)
EP (1) EP1537222B1 (de)
JP (2) JP4578240B2 (de)
AT (1) ATE501264T1 (de)
AU (1) AU2003258187A1 (de)
BR (1) BR0305767A (de)
CA (1) CA2493941A1 (de)
DE (1) DE60336324D1 (de)
HK (1) HK1074059A1 (de)
MX (1) MXPA05001537A (de)
NO (1) NO20041379L (de)
WO (1) WO2004015132A2 (de)

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DE60336324D1 (de) 2002-08-09 2011-04-21 Codexis Inc Enzymatische verfahren zur herstellung 4-substituierter 3-hydroxybuttersäure-derivate
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US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
EP3514242A3 (de) 2008-09-10 2019-08-28 Genomatica, Inc. Mikroorganismen zur herstellung von 1,4-butandiol
SG172231A1 (en) 2008-12-18 2011-07-28 Codexis Inc Recombinant halohydrin dehalogenase polypeptides
CN102459138A (zh) 2009-06-04 2012-05-16 基因组股份公司 分离发酵液成分的方法
VN29801A1 (de) 2009-06-04 2012-05-25
CN102482648B (zh) 2009-06-22 2014-12-10 科德克希思公司 酮还原酶介导的产生α氯代醇的立体选择性途径
CN102762735B (zh) 2009-10-13 2016-08-03 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
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US9080192B2 (en) 2010-02-10 2015-07-14 Codexis, Inc. Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
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US8420364B2 (en) 2010-06-30 2013-04-16 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
CN102168117B (zh) * 2011-01-12 2014-05-07 江苏阿尔法药业有限公司 一种制备(r)-4-氰基-3-羟基丁酸乙酯的方法
JP5705580B2 (ja) 2011-02-21 2015-04-22 公益財団法人微生物化学研究会 チオアミド化合物、チオアミド化合物の製造方法、［（４ｒ，６ｒ）−６−アミノエチル−１，３−ジオキサン−４−イル］アセテート誘導体の製造方法、及びアトルバスタチンの製造方法
CN102676597A (zh) * 2011-03-16 2012-09-19 苏州国镝医药科技有限公司 生物酶手性合成立普妥中间体ats-5
CN104685058B (zh) 2012-06-04 2020-07-07 基因组股份公司 制造4-羟基丁酸酯、1，4-丁二醇和相关化合物的微生物和方法
CN103695486A (zh) * 2014-01-03 2014-04-02 黄冈华阳药业有限公司 一种(3r,5r)-6-氰基-3,5-二羟基己酸叔丁酯的生物制备方法
CN105368886A (zh) * 2015-12-11 2016-03-02 江苏万年长药业有限公司 一种树脂固定卤醇脱卤酶催化合成(r)-4-氰基-3-羟基丁酸乙酯的工艺
CN109439700A (zh) * 2018-11-09 2019-03-08 浙江宏元药业股份有限公司 一种脱卤酶高效催化合成他汀类药物中间体的方法
CN111876448A (zh) * 2020-08-03 2020-11-03 连云港宏业化工有限公司 4-氰基-3-羟基丁酸乙酯合成方法

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Also Published As

Publication number Publication date
US7125693B2 (en) 2006-10-24
WO2004015132A3 (en) 2005-04-14
JP4578240B2 (ja) 2010-11-10
JP2005535330A (ja) 2005-11-24
ATE501264T1 (de) 2011-03-15
AU2003258187A8 (en) 2004-02-25
EP1537222B1 (de) 2011-03-09
AU2003258187A1 (en) 2004-02-25
HK1074059A1 (en) 2005-10-28
MXPA05001537A (es) 2005-11-17
DE60336324D1 (de) 2011-04-21
EP1537222A2 (de) 2005-06-08
EP1537222A4 (de) 2008-10-01
WO2004015132A2 (en) 2004-02-19
US20040137585A1 (en) 2004-07-15
JP2010172348A (ja) 2010-08-12
CA2493941A1 (en) 2004-02-19
BR0305767A (pt) 2005-05-24

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