NO20033634L - GLyT-1-inhibitorer - Google Patents

GLyT-1-inhibitorer

Info

Publication number
NO20033634L
NO20033634L NO20033634A NO20033634A NO20033634L NO 20033634 L NO20033634 L NO 20033634L NO 20033634 A NO20033634 A NO 20033634A NO 20033634 A NO20033634 A NO 20033634A NO 20033634 L NO20033634 L NO 20033634L
Authority
NO
Norway
Prior art keywords
glyt1 inhibitors
glyt1
inhibitors
neurological
pharmaceutical
Prior art date
Application number
NO20033634A
Other languages
English (en)
Other versions
NO329038B1 (no
NO20033634D0 (no
Inventor
Ian Egle
Ashok Tehim
William Delaney
Zhaoqing Wang
Richard Schumacher
Allen T Hopper
Shawn Maddarod
Original Assignee
Nps Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23026417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20033634(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nps Pharma Inc filed Critical Nps Pharma Inc
Publication of NO20033634D0 publication Critical patent/NO20033634D0/no
Publication of NO20033634L publication Critical patent/NO20033634L/no
Publication of NO329038B1 publication Critical patent/NO329038B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20033634A 2001-02-16 2003-08-15 Forbindelser med GLyT-1-transport inhiberende aktivitet, farmasoytisk preparat, anvendelse samt fremgangsmate for fremstilling NO329038B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26924101P 2001-02-16 2001-02-16
PCT/CA2002/000176 WO2002066456A2 (en) 2001-02-16 2002-02-15 Thiophene substituted amine derivatives as glyt-1 inhibitors

Publications (3)

Publication Number Publication Date
NO20033634D0 NO20033634D0 (no) 2003-08-15
NO20033634L true NO20033634L (no) 2003-10-08
NO329038B1 NO329038B1 (no) 2010-08-02

Family

ID=23026417

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20033634A NO329038B1 (no) 2001-02-16 2003-08-15 Forbindelser med GLyT-1-transport inhiberende aktivitet, farmasoytisk preparat, anvendelse samt fremgangsmate for fremstilling

Country Status (31)

Country Link
US (1) US6667336B2 (no)
EP (1) EP1368336B9 (no)
JP (2) JP2004523548A (no)
KR (1) KR100900020B1 (no)
CN (1) CN1219776C (no)
AT (1) ATE327986T1 (no)
AU (1) AU2002235682C1 (no)
BG (1) BG108164A (no)
BR (1) BR0207307A (no)
CA (1) CA2438367A1 (no)
CY (1) CY1105529T1 (no)
CZ (1) CZ20032503A3 (no)
DE (1) DE60211866T2 (no)
DK (1) DK1368336T3 (no)
EA (1) EA006636B1 (no)
EE (1) EE05329B1 (no)
ES (1) ES2266446T3 (no)
HK (1) HK1061025A1 (no)
HR (1) HRP20030696A2 (no)
HU (1) HUP0303185A3 (no)
IL (1) IL157194A (no)
MX (1) MXPA03007309A (no)
NO (1) NO329038B1 (no)
NZ (1) NZ527695A (no)
PL (1) PL365024A1 (no)
PT (1) PT1368336E (no)
SI (1) SI1368336T1 (no)
SK (1) SK287304B6 (no)
UA (1) UA75114C2 (no)
WO (1) WO2002066456A2 (no)
ZA (1) ZA200307201B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191165B1 (en) * 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
EP1830833B1 (en) * 2004-12-16 2010-01-27 Janssen Pharmaceutica N.V. Combination of a glycine transporter (glyt1) inhibitor and an antipsychotic for the treatment of symptoms of schizophrenia as well as its preparation and use thereof
US20090253918A1 (en) * 2006-10-02 2009-10-08 Janssen Pharmaceuticals, N.V. Novel intermediate for glyt1 inhibitor
WO2008065500A2 (en) * 2006-11-30 2008-06-05 Pfizer Products Inc. Heteroaryl amides as type i glycine transport inhibitors
CN103374057B (zh) * 2012-04-16 2015-08-19 中国医药集团总公司四川抗菌素工业研究所 一种对甘氨酸转运子具有抑制活性的化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3010599A1 (de) 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
BE885303A (fr) 1980-09-19 1981-03-19 Continental Pharma Glycinamides
US4383999A (en) 1981-05-26 1983-05-17 Smithkline Beckman Corporation Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
AU552050B2 (en) 1981-05-26 1986-05-22 Smithkline Beckman Corporation N-substituted azeheterocyclic carboxylic acids and their esters
US4514414A (en) 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
DK288385D0 (da) 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
FI864246A (fi) 1985-11-08 1987-05-09 Warner Lambert Co N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
US4772615A (en) 1985-11-08 1988-09-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
DE3787657T2 (de) 1986-01-07 1994-02-03 Novo Ind A S Bagsvaerd Aminosäure-Derivate.
JPH02129158A (ja) 1988-11-07 1990-05-17 Nippon Steel Corp 光学活性なグリシン誘導体及びその製造方法
IE913279A1 (en) * 1990-09-26 1992-04-08 Astra Ab (2-Thienyl)alkylamine Derivatives Having Neuroprotective¹Properties
ES2036926B1 (es) 1991-08-08 1994-01-16 Uriach & Cia Sa J "procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
PT871440E (pt) 1995-12-07 2006-07-31 Daniel C Javitt Tratamento de sintomas negativos e cognitivos de esquizofrenia com antagonistas da captacao de glicina
CA2619901A1 (en) * 1996-05-31 1997-12-04 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
US6191165B1 (en) 1996-05-31 2001-02-20 Allelix Neuroscience Inc. Pharmaceutical for treatment of neurological and neuropsychiatric disorders
DE69734215T2 (de) * 1996-07-22 2006-06-29 Novo Nordisk A/S Verbindungen mit Wachstumshormon-freisetzenden Eigenschaften
CN1284942A (zh) * 1998-01-09 2001-02-21 辉瑞大药厂 基质金属蛋白酶抑制剂
US6103743A (en) * 1999-08-06 2000-08-15 Allelix Neuroscience, Inc. Unsaturated amino acid derivatives

Also Published As

Publication number Publication date
CN1219776C (zh) 2005-09-21
HUP0303185A3 (en) 2008-12-29
CZ20032503A3 (cs) 2004-02-18
CA2438367A1 (en) 2002-08-29
SK287304B6 (sk) 2010-06-07
WO2002066456A2 (en) 2002-08-29
KR20040028719A (ko) 2004-04-03
US20030176489A1 (en) 2003-09-18
CN1491221A (zh) 2004-04-21
HRP20030696A2 (en) 2005-04-30
ZA200307201B (en) 2004-07-28
EA006636B1 (ru) 2006-02-24
MXPA03007309A (es) 2004-06-30
HUP0303185A2 (hu) 2003-12-29
US6667336B2 (en) 2003-12-23
AU2002235682C1 (en) 2008-12-11
KR100900020B1 (ko) 2009-06-01
UA75114C2 (en) 2006-03-15
HK1061025A1 (en) 2004-09-03
DE60211866D1 (de) 2006-07-06
BR0207307A (pt) 2004-08-17
EE200300394A (et) 2003-12-15
NO329038B1 (no) 2010-08-02
PL365024A1 (en) 2004-12-27
SK11442003A3 (sk) 2004-03-02
WO2002066456A3 (en) 2002-10-17
ES2266446T3 (es) 2007-03-01
BG108164A (en) 2004-07-30
PT1368336E (pt) 2006-10-31
NO20033634D0 (no) 2003-08-15
EP1368336B1 (en) 2006-05-31
AU2002235682B2 (en) 2007-04-26
SI1368336T1 (sl) 2006-10-31
EP1368336A2 (en) 2003-12-10
DE60211866T2 (de) 2007-06-14
ATE327986T1 (de) 2006-06-15
EA200300900A1 (ru) 2004-02-26
JP2010059182A (ja) 2010-03-18
IL157194A (en) 2006-12-31
CY1105529T1 (el) 2010-07-28
EP1368336B9 (en) 2007-02-14
NZ527695A (en) 2005-05-27
DK1368336T3 (da) 2006-10-02
JP2004523548A (ja) 2004-08-05
EE05329B1 (et) 2010-08-16

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Legal Events

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Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA, 0125 OSLO, NO

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