NO20045434L - En kombinasjon av en NMDA-antagonist og acetylkolinesteraseinhibitorer for behandlingen av Alzheimers sykdom - Google Patents
En kombinasjon av en NMDA-antagonist og acetylkolinesteraseinhibitorer for behandlingen av Alzheimers sykdomInfo
- Publication number
- NO20045434L NO20045434L NO20045434A NO20045434A NO20045434L NO 20045434 L NO20045434 L NO 20045434L NO 20045434 A NO20045434 A NO 20045434A NO 20045434 A NO20045434 A NO 20045434A NO 20045434 L NO20045434 L NO 20045434L
- Authority
- NO
- Norway
- Prior art keywords
- alzheimer
- disease
- treatment
- combination
- acetylcholinesterase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
2004-12-13 S a m m e n d r a g En farmasøytisk sammensetning omfattende (a) en effektiv mengde av en eller flere acetylkolinesterase inhibitorer eller et farmasøytisk effektivt salt derav og (b) en effektiv mengde av en eller flere NMDA-antagonister.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38446702P | 2002-05-31 | 2002-05-31 | |
DKPA200200844 | 2002-05-31 | ||
PCT/DK2003/000342 WO2003101458A1 (en) | 2002-05-31 | 2003-05-22 | A combination of an nmda-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20045434L true NO20045434L (no) | 2004-12-13 |
NO332754B1 NO332754B1 (no) | 2013-01-07 |
Family
ID=29713304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20045434A NO332754B1 (no) | 2002-05-31 | 2004-12-13 | Anvendelse av en sammensetning av en NMDA-antagonist og en acetylcholine esteraseinhibitor for behandling av Alzheimers sykdom. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1509232B1 (no) |
JP (1) | JP2005528431A (no) |
AT (1) | ATE414519T1 (no) |
AU (1) | AU2003227516B2 (no) |
BR (1) | BR0311375A (no) |
CY (1) | CY1108725T1 (no) |
DE (1) | DE60324788D1 (no) |
DK (1) | DK1509232T3 (no) |
ES (1) | ES2314200T3 (no) |
IL (1) | IL165255A0 (no) |
MX (1) | MXPA04011762A (no) |
NO (1) | NO332754B1 (no) |
NZ (1) | NZ536603A (no) |
PL (1) | PL373903A1 (no) |
PT (1) | PT1509232E (no) |
SI (1) | SI1509232T1 (no) |
WO (1) | WO2003101458A1 (no) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2502432A1 (en) * | 2002-10-24 | 2004-05-06 | Merz Pharma Gmbh & Co. Kgaa | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors |
EP1703902B1 (en) * | 2004-01-05 | 2010-11-03 | Merz Pharma GmbH & Co. KGaA | Memantine for the treatment of mild-to-moderate alzheimer's disease |
EP1708707A1 (en) * | 2004-01-22 | 2006-10-11 | Neurosearch A/S | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an n-methyl-d-aspartate (nmda) receptors antagonist |
TW200531680A (en) * | 2004-03-03 | 2005-10-01 | Merz Pharma Gmbh & Co Kgaa | Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease |
US20070213388A1 (en) * | 2004-03-19 | 2007-09-13 | Bruinsma Gosse B | Acetylcholinesterase Inhibitors and N-Methyl-D-Aspartate Antagonists Useful in the Treatment of of Cognitive Disorders |
RU2404750C2 (ru) * | 2004-11-23 | 2010-11-27 | Адамас Фармасьютикалс, Инк. | Композиция, содержащая основу или покрытие для замедленного высвобождения и антагонист nmda рецептора, способ введения такого nmda антагониста субъекту |
US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
EP1874282B1 (en) | 2005-04-06 | 2010-09-15 | Adamas Pharmaceuticals, Inc. | Methods and compositions for treatment of cns disorders |
CA2604617C (en) * | 2005-04-28 | 2014-06-17 | Eisai R&D Management Co., Ltd. | Composition containing anti-dementia drug |
TWI389709B (zh) * | 2005-12-01 | 2013-03-21 | Novartis Ag | 經皮治療系統 |
EP2089383B1 (en) | 2006-11-09 | 2015-09-16 | Probiodrug AG | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
ATE554085T1 (de) | 2006-11-30 | 2012-05-15 | Probiodrug Ag | Neue inhibitoren von glutaminylcyclase |
CA2679446C (en) | 2007-03-01 | 2016-05-17 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
EP2142514B1 (en) | 2007-04-18 | 2014-12-24 | Probiodrug AG | Thiourea derivatives as glutaminyl cyclase inhibitors |
CA2772488C (en) | 2009-09-11 | 2018-04-17 | Probiodrug Ag | Heterocyclic derivatives as inhibitors of glutaminyl cyclase |
CN102883601A (zh) | 2009-12-02 | 2013-01-16 | 阿达玛斯医药公司 | 金刚烷胺组合物及其使用方法 |
EP2533645B1 (en) | 2010-02-09 | 2016-07-27 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
EP2545047B9 (en) | 2010-03-10 | 2015-06-10 | Probiodrug AG | Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5) |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
ES2625135T3 (es) | 2010-07-05 | 2017-07-18 | Gambro Lundia Ab | Un dispositivo de ultrafiltración ambulatoria, métodos relacionados y un producto de programa informático |
TR201007110A2 (tr) | 2010-08-25 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Sinerjik etki gösteren kombinasyonlar |
WO2012048871A1 (en) | 2010-10-12 | 2012-04-19 | Merz Pharma Gmbh & Co. Kgaa | Memantine for improving cognitive performance in subjects |
ES2570167T3 (es) | 2011-03-16 | 2016-05-17 | Probiodrug Ag | Derivados de benzimidazol como inhibidores de glutaminil ciclasa |
FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
WO2013160728A1 (en) * | 2012-04-26 | 2013-10-31 | Alma Mater Studiorum - Universita' Di Bologna | Dual targeting compounds for the treatment of alzheimer's disease |
WO2014055047A1 (en) * | 2012-08-31 | 2014-04-10 | Mahmut Bilgic | Combination of idebenone and donezepil |
WO2014035355A1 (en) * | 2012-08-31 | 2014-03-06 | Mahmut Bilgic | Pharmaceutical combination comprising idebenone and memantine |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
GEP201706739B (en) * | 2012-12-13 | 2017-09-25 | H Lundbeck As | Compositions comprising vortioxetine and donepezil |
AU2014228512A1 (en) | 2013-03-15 | 2015-10-01 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
EP2968237A4 (en) | 2013-03-15 | 2016-08-31 | Univ Johns Hopkins | METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION |
US10154971B2 (en) | 2013-06-17 | 2018-12-18 | Adamas Pharma, Llc | Methods of administering amantadine |
US10925834B2 (en) | 2015-05-22 | 2021-02-23 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
SG11201809726UA (en) * | 2016-05-18 | 2018-12-28 | Suven Life Sciences Ltd | Triple combination of pure 5-ht6 receptor antagonists, acetylcholinesterase inhibitors and nmda receptor antagonist |
GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
KR101938872B1 (ko) * | 2016-09-30 | 2019-01-16 | 주식회사 바이오파마티스 | 도네페질 또는 그의 약학적으로 허용 가능한 염 및 메만틴 또는 그의 약학적으로 허용 가능한 염을 함유하는 치매 및 인지기능 장애 예방 또는 치료용 약학 조성물 및 이의 제조방법 |
EP3532060A4 (en) * | 2016-10-28 | 2020-08-26 | Chase Pharmaceuticals Corporation | COMBINATIONS AND USE OF MEMANTINE |
TR201619184A2 (tr) | 2016-12-22 | 2018-07-23 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Donepezi̇l ve memanti̇n i̇çeren kapsül bi̇leşi̇mleri̇ |
EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
EP4238555A3 (en) | 2019-05-31 | 2023-09-20 | Tecnimede, Sociedade Técnico-Medicinal, SA | Immediate release fixed-dose combination of memantine and donepezil |
-
2003
- 2003-05-22 NZ NZ536603A patent/NZ536603A/en not_active IP Right Cessation
- 2003-05-22 IL IL16525503A patent/IL165255A0/xx unknown
- 2003-05-22 DE DE60324788T patent/DE60324788D1/de not_active Expired - Lifetime
- 2003-05-22 AT AT03724895T patent/ATE414519T1/de active
- 2003-05-22 DK DK03724895T patent/DK1509232T3/da active
- 2003-05-22 JP JP2004508815A patent/JP2005528431A/ja active Pending
- 2003-05-22 WO PCT/DK2003/000342 patent/WO2003101458A1/en active Application Filing
- 2003-05-22 PT PT03724895T patent/PT1509232E/pt unknown
- 2003-05-22 MX MXPA04011762A patent/MXPA04011762A/es active IP Right Grant
- 2003-05-22 PL PL03373903A patent/PL373903A1/xx not_active Application Discontinuation
- 2003-05-22 EP EP03724895A patent/EP1509232B1/en not_active Revoked
- 2003-05-22 BR BR0311375-2A patent/BR0311375A/pt not_active IP Right Cessation
- 2003-05-22 SI SI200331469T patent/SI1509232T1/sl unknown
- 2003-05-22 ES ES03724895T patent/ES2314200T3/es not_active Expired - Lifetime
- 2003-05-22 AU AU2003227516A patent/AU2003227516B2/en not_active Ceased
-
2004
- 2004-12-13 NO NO20045434A patent/NO332754B1/no not_active IP Right Cessation
-
2009
- 2009-01-21 CY CY20091100080T patent/CY1108725T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PL373903A1 (en) | 2005-09-19 |
CY1108725T1 (el) | 2014-04-09 |
NZ536603A (en) | 2007-06-29 |
ES2314200T3 (es) | 2009-03-16 |
PT1509232E (pt) | 2009-01-07 |
NO332754B1 (no) | 2013-01-07 |
MXPA04011762A (es) | 2005-03-31 |
DK1509232T3 (da) | 2009-02-23 |
BR0311375A (pt) | 2005-03-15 |
EP1509232A1 (en) | 2005-03-02 |
ATE414519T1 (de) | 2008-12-15 |
DE60324788D1 (de) | 2009-01-02 |
WO2003101458A1 (en) | 2003-12-11 |
IL165255A0 (en) | 2005-12-18 |
EP1509232B1 (en) | 2008-11-19 |
AU2003227516A1 (en) | 2003-12-19 |
JP2005528431A (ja) | 2005-09-22 |
SI1509232T1 (sl) | 2009-04-30 |
AU2003227516B2 (en) | 2008-03-20 |
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Legal Events
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CREP | Change of representative |
Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104 |
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MM1K | Lapsed by not paying the annual fees |