NO20033130L - Anvendelse av 2-amino-4-heteroaryletyl-tiazolin som inhibitorer av induktibel NO-syntase - Google Patents
Anvendelse av 2-amino-4-heteroaryletyl-tiazolin som inhibitorer av induktibel NO-syntaseInfo
- Publication number
- NO20033130L NO20033130L NO20033130A NO20033130A NO20033130L NO 20033130 L NO20033130 L NO 20033130L NO 20033130 A NO20033130 A NO 20033130A NO 20033130 A NO20033130 A NO 20033130A NO 20033130 L NO20033130 L NO 20033130L
- Authority
- NO
- Norway
- Prior art keywords
- synthase
- inducible
- inhibitors
- amino
- heteroarylethylthiazoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0114509A FR2832151B1 (fr) | 2001-11-09 | 2001-11-09 | Utilisation de derives de 2-amino-4-heteroarylethyl-thiazoline comme inhibiteurs de no-synthase inductible |
| US35297702P | 2002-01-30 | 2002-01-30 | |
| PCT/FR2002/003809 WO2003040142A1 (fr) | 2001-11-09 | 2002-11-07 | Derives de 2-amino-4-heteroarylethyl thiazoline et leur utilisation comme inhibiteurs de no-synthase inductible |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20033130D0 NO20033130D0 (no) | 2003-07-08 |
| NO20033130L true NO20033130L (no) | 2003-08-27 |
Family
ID=26213259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20033130A NO20033130L (no) | 2001-11-09 | 2003-07-08 | Anvendelse av 2-amino-4-heteroaryletyl-tiazolin som inhibitorer av induktibel NO-syntase |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6872740B2 (es) |
| EP (1) | EP1446402B1 (es) |
| JP (1) | JP4365681B2 (es) |
| AT (1) | ATE308541T1 (es) |
| AU (1) | AU2002358874B2 (es) |
| BR (1) | BR0206363A (es) |
| CA (1) | CA2465691C (es) |
| DE (1) | DE60207104T2 (es) |
| DK (1) | DK1446402T3 (es) |
| ES (1) | ES2250731T3 (es) |
| HR (1) | HRP20040401A2 (es) |
| HU (1) | HUP0402038A2 (es) |
| IL (2) | IL161842A0 (es) |
| MA (1) | MA27077A1 (es) |
| MX (1) | MXPA04003766A (es) |
| NO (1) | NO20033130L (es) |
| PL (1) | PL370322A1 (es) |
| RU (1) | RU2004117525A (es) |
| WO (1) | WO2003040142A1 (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2256583T3 (es) * | 2001-11-09 | 2006-07-16 | Aventis Pharma S.A. | Derivados de 2-amino-tiazolina y su uso como inhibidores de la no-sintasa inducible. |
| ES2572263T3 (es) * | 2005-10-25 | 2016-05-31 | Shionogi & Co | Derivados de dihidrooxazina y tetrahidropirimidina como inhibidores de BACE 1 |
| EP2147914B1 (en) | 2007-04-24 | 2014-06-04 | Shionogi&Co., Ltd. | Aminodihydrothiazine derivatives substituted with cyclic groups |
| EP2151435A4 (en) | 2007-04-24 | 2011-09-14 | Shionogi & Co | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
| KR101324426B1 (ko) | 2008-06-13 | 2013-10-31 | 시오노기세야쿠 가부시키가이샤 | β 세크레타제 저해 작용을 갖는 황 함유 복소환 유도체 |
| EP2360155A4 (en) | 2008-10-22 | 2012-06-20 | Shionogi & Co | 2-AMINOPYRIDIN-4-ON AND 2-AMINOPYRIDINE DERIVATIVE WITH BACE1-HEMDERING EFFECT |
| CN102834384A (zh) * | 2009-12-11 | 2012-12-19 | 盐野义制药株式会社 | *嗪衍生物 |
| WO2012057248A1 (ja) | 2010-10-29 | 2012-05-03 | 塩野義製薬株式会社 | ナフチリジン誘導体 |
| US9018219B2 (en) | 2010-10-29 | 2015-04-28 | Shionogi & Co., Ltd. | Fused aminodihydropyrimidine derivative |
| EP2703399A4 (en) | 2011-04-26 | 2014-10-15 | Shionogi & Co | OXAZINE DERIVATIVE AND BACE-1 HEMMER THEREOF |
| WO2014065434A1 (en) | 2012-10-24 | 2014-05-01 | Shionogi & Co., Ltd. | Dihydrooxazine or oxazepine derivatives having bace1 inhibitory activity |
| EP3210602B1 (en) * | 2014-10-24 | 2021-02-17 | Korea Institute of Ocean Science and Technology | Composition for preventing or treating neurodegenerative diseases, containing ramalin |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994012165A2 (en) * | 1992-11-27 | 1994-06-09 | The Wellcome Foundation Limited | Enzyme inhibitors |
| CN1077886C (zh) * | 1993-10-21 | 2002-01-16 | G·D·瑟尔公司 | 用作一氧化一氮合酶抑制剂的脒基衍生物 |
| AU4149696A (en) * | 1994-11-15 | 1996-06-06 | Merck & Co., Inc. | Substituted heterocycles as inhibitors of nitric oxide synthase |
| FR2810037B1 (fr) * | 2000-06-09 | 2004-04-23 | Aventis Pharma Sa | Utilisation de derives de 2-aminothiazoline comme inhibiteurs de no-synthase inductible |
-
2002
- 2002-11-07 JP JP2003542188A patent/JP4365681B2/ja not_active Expired - Fee Related
- 2002-11-07 AT AT02793211T patent/ATE308541T1/de active
- 2002-11-07 IL IL16184202A patent/IL161842A0/xx unknown
- 2002-11-07 HU HU0402038A patent/HUP0402038A2/hu unknown
- 2002-11-07 RU RU2004117525/04A patent/RU2004117525A/ru not_active Application Discontinuation
- 2002-11-07 DK DK02793211T patent/DK1446402T3/da active
- 2002-11-07 BR BR0206363-8A patent/BR0206363A/pt not_active Application Discontinuation
- 2002-11-07 EP EP02793211A patent/EP1446402B1/fr not_active Expired - Lifetime
- 2002-11-07 CA CA2465691A patent/CA2465691C/fr not_active Expired - Fee Related
- 2002-11-07 WO PCT/FR2002/003809 patent/WO2003040142A1/fr active IP Right Grant
- 2002-11-07 ES ES02793211T patent/ES2250731T3/es not_active Expired - Lifetime
- 2002-11-07 MX MXPA04003766A patent/MXPA04003766A/es active IP Right Grant
- 2002-11-07 AU AU2002358874A patent/AU2002358874B2/en not_active Ceased
- 2002-11-07 DE DE60207104T patent/DE60207104T2/de not_active Expired - Lifetime
- 2002-11-07 PL PL02370322A patent/PL370322A1/xx unknown
- 2002-11-08 US US10/291,110 patent/US6872740B2/en not_active Expired - Fee Related
-
2003
- 2003-07-08 NO NO20033130A patent/NO20033130L/no unknown
-
2004
- 2004-04-22 MA MA27645A patent/MA27077A1/fr unknown
- 2004-05-06 HR HR20040401A patent/HRP20040401A2/hr not_active Application Discontinuation
- 2004-05-06 IL IL161842A patent/IL161842A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2250731T3 (es) | 2006-04-16 |
| IL161842A (en) | 2010-12-30 |
| EP1446402A1 (fr) | 2004-08-18 |
| ATE308541T1 (de) | 2005-11-15 |
| NO20033130D0 (no) | 2003-07-08 |
| RU2004117525A (ru) | 2005-04-20 |
| US20030225140A1 (en) | 2003-12-04 |
| HRP20040401A2 (en) | 2004-10-31 |
| IL161842A0 (en) | 2005-11-20 |
| JP2005509651A (ja) | 2005-04-14 |
| AU2002358874B2 (en) | 2007-09-06 |
| DE60207104D1 (de) | 2005-12-08 |
| EP1446402B1 (fr) | 2005-11-02 |
| HUP0402038A2 (hu) | 2005-01-28 |
| CA2465691C (fr) | 2011-07-19 |
| JP4365681B2 (ja) | 2009-11-18 |
| WO2003040142A1 (fr) | 2003-05-15 |
| DE60207104T2 (de) | 2006-07-13 |
| PL370322A1 (en) | 2005-05-16 |
| MXPA04003766A (es) | 2004-07-29 |
| DK1446402T3 (da) | 2006-03-06 |
| CA2465691A1 (fr) | 2003-05-15 |
| US6872740B2 (en) | 2005-03-29 |
| MA27077A1 (fr) | 2004-12-20 |
| BR0206363A (pt) | 2003-12-23 |
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