NO20030606L - Modifisert gj¶r og anvendelser derav, n¶rmere bestemt for fremstilling avsteroidderivater - Google Patents

Modifisert gj¶r og anvendelser derav, n¶rmere bestemt for fremstilling avsteroidderivater

Info

Publication number
NO20030606L
NO20030606L NO20030606A NO20030606A NO20030606L NO 20030606 L NO20030606 L NO 20030606L NO 20030606 A NO20030606 A NO 20030606A NO 20030606 A NO20030606 A NO 20030606A NO 20030606 L NO20030606 L NO 20030606L
Authority
NO
Norway
Prior art keywords
manufacture
steroid derivatives
modified makes
modified
steroid
Prior art date
Application number
NO20030606A
Other languages
English (en)
Other versions
NO20030606D0 (no
NO334484B1 (no
Inventor
Bruno Dumas
Gilles Cauet
Tilman Achstetter
Eric Degryse
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO20030606D0 publication Critical patent/NO20030606D0/no
Publication of NO20030606L publication Critical patent/NO20030606L/no
Publication of NO334484B1 publication Critical patent/NO334484B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • C12N9/0087Steroid 21-monooxygenase (1.14.99.10)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/06Hydroxylating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
NO20030606A 2000-08-08 2003-02-07 Gjærstamme med redusert 20alfa-hydroksysteroid-dehydrogenase (20alfaHSD)-aktivitet og anvendelser derav, nærmere bestemt for fremstilling av steroidderivater. NO334484B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0010437A FR2812884B1 (fr) 2000-08-08 2000-08-08 Levures modifiees et utilisations, notamment pour la production de derives steroidiens
PCT/FR2001/002417 WO2002012536A1 (fr) 2000-08-08 2001-07-24 Levures modifiees et utilisations, notamment pour la production de derives steroidiens

Publications (3)

Publication Number Publication Date
NO20030606D0 NO20030606D0 (no) 2003-02-07
NO20030606L true NO20030606L (no) 2003-02-07
NO334484B1 NO334484B1 (no) 2014-03-17

Family

ID=8853403

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030606A NO334484B1 (no) 2000-08-08 2003-02-07 Gjærstamme med redusert 20alfa-hydroksysteroid-dehydrogenase (20alfaHSD)-aktivitet og anvendelser derav, nærmere bestemt for fremstilling av steroidderivater.

Country Status (22)

Country Link
US (2) US7879592B2 (no)
EP (1) EP1313873B1 (no)
JP (1) JP4864277B2 (no)
KR (1) KR100860702B1 (no)
AR (1) AR030080A1 (no)
AT (1) ATE390479T1 (no)
AU (2) AU2001278562B2 (no)
BR (1) BRPI0113048B8 (no)
CA (1) CA2418370C (no)
CY (1) CY1108080T1 (no)
DE (1) DE60133396T2 (no)
DK (1) DK1313873T3 (no)
ES (1) ES2300347T3 (no)
FR (1) FR2812884B1 (no)
IL (2) IL154294A0 (no)
MX (1) MXPA03000702A (no)
NO (1) NO334484B1 (no)
NZ (1) NZ523612A (no)
PT (1) PT1313873E (no)
TW (1) TWI315739B (no)
WO (1) WO2002012536A1 (no)
ZA (1) ZA200300376B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812884B1 (fr) * 2000-08-08 2002-11-08 Aventis Pharma Sa Levures modifiees et utilisations, notamment pour la production de derives steroidiens
FR2820145B1 (fr) * 2001-01-31 2004-01-23 Aventis Pharma Sa Souche de levure produisant des steroides de facon autonome
FR2976949B1 (fr) 2011-06-21 2015-08-28 Sanofi Sa Procede de preparation de levures genetiquement transformees capables de produire une molecule d'interet a haut titre

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5571250A (en) 1978-11-22 1980-05-29 Hatano Kk Paper for paper box with lid and method of assembling paper box with lid by using same
BE889407A (fr) 1980-06-27 1981-10-16 Mallinckrodt Inc Amelioration du procede de preparation d'un lysat de limule
JPS62181571A (ja) 1986-08-11 1987-08-08 Canon Inc 画像処理装置
JPS63181571A (ja) 1987-01-22 1988-07-26 Matsushita Electric Ind Co Ltd 自動焦点整合装置
JPS6447380A (en) * 1987-08-19 1989-02-21 Agency Ind Science Techn Steroid-oxidizing yeast strain
JPS6471250A (en) 1987-09-11 1989-03-16 Nec Corp Multi-function telephone set
EP0340878B1 (en) 1988-05-06 2001-05-16 Aventis Pharma S.A. Process for the biochemical oxidation of steroids and genetically engineered cells to be used therefor
JPH0231680A (ja) * 1988-07-22 1990-02-01 Agency Of Ind Science & Technol チトクロムP450c↓2↓1産生酵母菌株
CN1042567A (zh) 1988-09-23 1990-05-30 吉斯特-布罗卡迪斯公司 类固醇多步氧化方法和所用的遗传工程细胞
JPH02249488A (ja) * 1989-03-22 1990-10-05 Sumitomo Chem Co Ltd チトクロムP450↓c↓2↓1と酵母NADPH‐チトクロムP450還元酵素の融合酸化酵素、該酵素をコードする遺伝子および該酵素の製造方法
JP2645130B2 (ja) * 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
FR2678611B1 (fr) 1991-07-04 1995-01-20 Roussel Uclaf Nouveaux esters pyrethrinouides de l'alcool 1,3,4,5,6,7-hexahydro 1,3-dioxo-2h-isoindol-2-yl-methylique, leur procede de preparation et leur application comme pesticides.
JP3363197B2 (ja) 1992-06-18 2003-01-08 麒麟麦酒株式会社 アルコールアセチルトランスフェラーゼ遺伝子およびその利用
US5547868A (en) * 1993-06-09 1996-08-20 Regents Of The University Of California Cholesterol disposal fusion enzymes
IL116872A (en) * 1995-02-15 2004-12-15 Aventis Pharma Sa Delta 5,7-Strol Reductase from Arbidopsis Thaliana
JP4093598B2 (ja) 1995-03-14 2008-06-04 大関株式会社 新規なアルコールアセチルトランスフェラーゼ遺伝子
DE19744212B4 (de) 1997-09-30 2006-01-19 Schering Ag Verfahren zur Herstellung von Ergosterol und dessen Zwischenprodukten mittels rekombinanter Hefen
US6303302B1 (en) * 1997-11-19 2001-10-16 The Whitehead Institute For Biomedical Research Regulation of fungal gene expression
FR2774393B1 (fr) * 1998-02-05 2000-03-24 Hoechst Marion Roussel Inc Souches de levure ayant le gene atf2 interrompu et leurs applications
FR2799206A1 (fr) 1999-10-05 2001-04-06 Transgene Sa Procede de production de steroides modifies par fermentation de levures
FR2812884B1 (fr) 2000-08-08 2002-11-08 Aventis Pharma Sa Levures modifiees et utilisations, notamment pour la production de derives steroidiens
FR2820145B1 (fr) 2001-01-31 2004-01-23 Aventis Pharma Sa Souche de levure produisant des steroides de facon autonome

Also Published As

Publication number Publication date
US20040082025A1 (en) 2004-04-29
AR030080A1 (es) 2003-08-13
BRPI0113048B1 (pt) 2015-12-22
KR100860702B1 (ko) 2008-09-26
DK1313873T3 (da) 2008-07-14
CY1108080T1 (el) 2014-02-12
JP4864277B2 (ja) 2012-02-01
KR20030024842A (ko) 2003-03-26
NO20030606D0 (no) 2003-02-07
ZA200300376B (en) 2004-01-22
BRPI0113048B8 (pt) 2021-05-25
ATE390479T1 (de) 2008-04-15
CA2418370C (fr) 2014-03-11
EP1313873B1 (fr) 2008-03-26
JP2004505634A (ja) 2004-02-26
ES2300347T3 (es) 2008-06-16
PT1313873E (pt) 2008-05-27
NO334484B1 (no) 2014-03-17
FR2812884A1 (fr) 2002-02-15
AU7856201A (en) 2002-02-18
BR0113048A (pt) 2003-07-01
EP1313873A1 (fr) 2003-05-28
DE60133396T2 (de) 2009-07-09
DE60133396D1 (de) 2008-05-08
AU2001278562B2 (en) 2006-07-20
US7879592B2 (en) 2011-02-01
WO2002012536A1 (fr) 2002-02-14
TWI315739B (en) 2009-10-11
US8173402B2 (en) 2012-05-08
IL154294A0 (en) 2003-09-17
NZ523612A (en) 2004-11-26
US20110104749A1 (en) 2011-05-05
IL154294A (en) 2010-05-31
CA2418370A1 (fr) 2002-02-14
MXPA03000702A (es) 2003-06-04
FR2812884B1 (fr) 2002-11-08

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