NO20030127L - Indolderivater nyttige for behandling av CNS-forstyrrelser - Google Patents

Indolderivater nyttige for behandling av CNS-forstyrrelser

Info

Publication number
NO20030127L
NO20030127L NO20030127A NO20030127A NO20030127L NO 20030127 L NO20030127 L NO 20030127L NO 20030127 A NO20030127 A NO 20030127A NO 20030127 A NO20030127 A NO 20030127A NO 20030127 L NO20030127 L NO 20030127L
Authority
NO
Norway
Prior art keywords
treatment
cns disorders
indole derivatives
derivatives useful
useful
Prior art date
Application number
NO20030127A
Other languages
English (en)
Other versions
NO323799B1 (no
NO20030127D0 (no
Inventor
Jakob Felding
Benny Bang-Andersen
Garrick Paul Smith
Kim Andersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20030127L publication Critical patent/NO20030127L/no
Publication of NO20030127D0 publication Critical patent/NO20030127D0/no
Publication of NO323799B1 publication Critical patent/NO323799B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO20030127A 2000-07-21 2003-01-10 Indolderivater, farmasoytisk sammensetning inneholdende dem og deres anvendelse. NO323799B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001123 2000-07-21
PCT/DK2001/000507 WO2002008223A1 (en) 2000-07-21 2001-07-17 Indole derivatives useful for the treatment of cns disorders

Publications (3)

Publication Number Publication Date
NO20030127L true NO20030127L (no) 2003-01-10
NO20030127D0 NO20030127D0 (no) 2003-01-10
NO323799B1 NO323799B1 (no) 2007-07-09

Family

ID=8159625

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030127A NO323799B1 (no) 2000-07-21 2003-01-10 Indolderivater, farmasoytisk sammensetning inneholdende dem og deres anvendelse.

Country Status (29)

Country Link
US (1) US6743809B2 (no)
EP (1) EP1305307B1 (no)
JP (1) JP2004504396A (no)
KR (1) KR100851793B1 (no)
CN (1) CN1264838C (no)
AR (1) AR029858A1 (no)
AT (1) ATE266024T1 (no)
AU (2) AU2001281738B2 (no)
BG (1) BG107528A (no)
BR (1) BR0112998A (no)
CA (1) CA2416212C (no)
CZ (1) CZ301114B6 (no)
DE (1) DE60103162T2 (no)
EA (1) EA004749B1 (no)
ES (1) ES2219554T3 (no)
HK (1) HK1059782A1 (no)
HR (1) HRP20030015A2 (no)
HU (1) HUP0302820A3 (no)
IL (2) IL153605A0 (no)
IS (1) IS2172B (no)
MX (1) MXPA02012927A (no)
NO (1) NO323799B1 (no)
NZ (1) NZ523436A (no)
PT (1) PT1305307E (no)
SK (1) SK286701B6 (no)
TR (1) TR200401488T4 (no)
UA (1) UA73995C2 (no)
WO (1) WO2002008223A1 (no)
ZA (1) ZA200300287B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004291297B2 (en) 2003-11-17 2011-06-23 Boehringer Ingelheim International Gmbh Novel piperidine-substituted indoles- or heteroderivatives thereof
TWI391387B (zh) * 2004-05-12 2013-04-01 Eisai R&D Man Co Ltd 具有哌啶環之吲哚衍生物
WO2006117314A2 (en) 2005-04-30 2006-11-09 Boehringer Ingelheim International Gmbh Novel piperidin- substituted indoles and their use as ccr-3 modulators
CA2667547C (en) 2006-10-27 2014-07-29 Boehringer Ingelheim International Gmbh Piperidyl-propane-thiol ccr3 modulators
CN101486654B (zh) * 2009-03-04 2012-10-10 西安近代化学研究所 2-甲基-3-硝基苯乙酸合成方法
CN110041318B (zh) * 2018-01-17 2022-07-29 中国科学院上海药物研究所 一类多巴胺d5受体激动剂及其制备和应用
CN110498789B (zh) * 2018-05-17 2022-04-05 上海医药工业研究院 芳烷哌啶类衍生物及其在多靶点抗抑郁症中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
AT332401B (de) * 1973-11-26 1976-09-27 Roussel Uclaf Verfahren zur herstellung von neuen (4'-(3''-indolyl)-piperidino)-alkylarylketonderivaten
US4997841A (en) * 1987-08-13 1991-03-05 Glaxo Group Limited Indole derivatives
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
CA2141810A1 (en) * 1992-08-05 1994-02-17 Ian A. Cliffe Amide derivatives
DK0695301T3 (da) * 1993-04-22 1996-12-09 Pfizer Ltd Indolderivater som 5-HT1-lignende agonister til anvendelse ved migræne
ES2063700B1 (es) * 1993-04-28 1995-07-16 Vita Invest Sa Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9718712D0 (en) * 1997-09-03 1997-11-12 Merck Sharp & Dohme Theraputic Agents

Also Published As

Publication number Publication date
AU2001281738B2 (en) 2006-12-21
EP1305307B1 (en) 2004-05-06
AU8173801A (en) 2002-02-05
ES2219554T3 (es) 2004-12-01
CA2416212A1 (en) 2002-01-31
KR20030017643A (ko) 2003-03-03
ATE266024T1 (de) 2004-05-15
TR200401488T4 (tr) 2004-08-23
PT1305307E (pt) 2004-09-30
PL359157A1 (en) 2004-08-23
NO323799B1 (no) 2007-07-09
IS2172B (is) 2006-11-15
BG107528A (bg) 2003-10-31
NZ523436A (en) 2004-07-30
IS6663A (is) 2002-12-23
MXPA02012927A (es) 2003-05-15
DE60103162D1 (de) 2004-06-09
CN1264838C (zh) 2006-07-19
KR100851793B1 (ko) 2008-08-13
HUP0302820A3 (en) 2006-04-28
BR0112998A (pt) 2003-06-24
CZ2003196A3 (cs) 2003-05-14
IL153605A (en) 2008-07-08
HK1059782A1 (en) 2004-07-16
IL153605A0 (en) 2003-07-06
HUP0302820A2 (hu) 2003-12-29
AR029858A1 (es) 2003-07-16
WO2002008223A1 (en) 2002-01-31
CN1451002A (zh) 2003-10-22
CA2416212C (en) 2007-10-30
SK2032003A3 (en) 2003-06-03
ZA200300287B (en) 2004-03-02
CZ301114B6 (cs) 2009-11-11
DE60103162T2 (de) 2005-05-04
JP2004504396A (ja) 2004-02-12
UA73995C2 (en) 2005-10-17
US20030166664A1 (en) 2003-09-04
HRP20030015A2 (en) 2005-02-28
EA200300179A1 (ru) 2003-06-26
US6743809B2 (en) 2004-06-01
EA004749B1 (ru) 2004-08-26
SK286701B6 (sk) 2009-03-05
NO20030127D0 (no) 2003-01-10
EP1305307A1 (en) 2003-05-02

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