NO20022557L - 2,4-diaminopyrimidinforbindelser nyttige som immunosuppreserende midler - Google Patents
2,4-diaminopyrimidinforbindelser nyttige som immunosuppreserende midlerInfo
- Publication number
- NO20022557L NO20022557L NO20022557A NO20022557A NO20022557L NO 20022557 L NO20022557 L NO 20022557L NO 20022557 A NO20022557 A NO 20022557A NO 20022557 A NO20022557 A NO 20022557A NO 20022557 L NO20022557 L NO 20022557L
- Authority
- NO
- Norway
- Prior art keywords
- immunosuppressants
- compounds useful
- diaminopyrimidine compounds
- compounds
- alkylaminocarbonylamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Abstract
Nye forbindelser ifølge formel (I) og farmasøytisk akseptable salter, solvater eller hydrater derav; hvor hver forekomst av A er uavhengig valgt fra CH eller N; X er valgt fra gruppen bestående av -CH2-. -O-, -NH-, (CT-CeJalkylamino-, (d- C6)alkylaminokarbonylamino-, (CrCeJalkylkarbonylamino-, (d- C6)alkylsulfonylamino-, fenylsulfonylamino-, karbonyl, -NH-C(O)-, -N(CrC6)alkyl- C(O)-, S(O)y- hvor y er O, 1 eller 2, og n i -(CH2)n- er 1, 2 eller 3; og R1, R2 og R3 er som beskrevet heri; farmasøytiske preparater som innbefatter disse forbindelsene, og fremgangsmåter for behandling av autoimmun sykdom, inflammasjon, allergi, transplantatavstøtning og andre omstendigheter hvor administrering av et immunsuppressivt middel som er av terapeutisk fordel, er beskrevet.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16822499P | 1999-11-30 | 1999-11-30 | |
PCT/IB2000/001628 WO2001040215A1 (en) | 1999-11-30 | 2000-11-09 | 2,4-diaminopyrimidine compounds usful as immunosuppressants |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20022557L true NO20022557L (no) | 2002-05-29 |
NO20022557D0 NO20022557D0 (no) | 2002-05-29 |
Family
ID=22610621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20022557A NO20022557D0 (no) | 1999-11-30 | 2002-05-29 | 2,4-diaminopyrimidinforbindelser nyttige som immunosuppreserende midler |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP1242403B1 (no) |
JP (1) | JP3955468B2 (no) |
KR (1) | KR20020059826A (no) |
CN (1) | CN1402720A (no) |
AP (1) | AP2002002530A0 (no) |
AT (1) | ATE315036T1 (no) |
AU (1) | AU1047601A (no) |
BG (1) | BG106695A (no) |
BR (1) | BR0015995A (no) |
CA (1) | CA2392971C (no) |
CO (1) | CO5261519A1 (no) |
CZ (1) | CZ20021703A3 (no) |
DE (1) | DE60025385T2 (no) |
EA (1) | EA200200411A1 (no) |
EE (1) | EE200200275A (no) |
ES (1) | ES2253266T3 (no) |
GT (1) | GT200000200A (no) |
HN (1) | HN2000000264A (no) |
HU (1) | HUP0203300A3 (no) |
IL (1) | IL149103A0 (no) |
IS (1) | IS6339A (no) |
MA (1) | MA26846A1 (no) |
MX (1) | MXPA02005350A (no) |
NO (1) | NO20022557D0 (no) |
OA (1) | OA12097A (no) |
PA (1) | PA8506801A1 (no) |
PE (1) | PE20010900A1 (no) |
PL (1) | PL355946A1 (no) |
SV (1) | SV2002000231A (no) |
TN (1) | TNSN00232A1 (no) |
TR (1) | TR200201431T2 (no) |
UY (1) | UY26455A1 (no) |
WO (1) | WO2001040215A1 (no) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001060816A1 (en) * | 2000-02-17 | 2001-08-23 | Amgen Inc. | Kinase inhibitors |
EA200300205A1 (ru) * | 2000-08-31 | 2003-06-26 | Пфайзер Продактс Инк. | Производные пиразола и их применение в качестве ингибиторов протеинкиназы |
US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
CA2422377C (en) | 2000-09-15 | 2010-04-13 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
EP1345922B1 (en) | 2000-12-21 | 2006-05-31 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
WO2003030909A1 (en) * | 2001-09-25 | 2003-04-17 | Bayer Pharmaceuticals Corporation | 2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer |
KR20050032105A (ko) | 2002-08-02 | 2005-04-06 | 버텍스 파마슈티칼스 인코포레이티드 | Gsk-3의 억제제로서 유용한 피라졸 조성물 |
US20040204458A1 (en) | 2002-08-16 | 2004-10-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of Lck inhibitors for treatment of immunologic diseases |
DE10237423A1 (de) * | 2002-08-16 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von LCK-Inhibitoren für die Behandlung von immunologischen Erkrankungen |
KR20060133552A (ko) * | 2004-01-16 | 2006-12-26 | 노파르티스 아게 | 2,4-디아미노피리미딘 및 심장근육발생 유도를 위한 그의용도 |
ATE512144T1 (de) * | 2004-10-12 | 2011-06-15 | Decode Genetics Ehf | Peri-substituierte bicyclische arylsulfonamide gegen arterielle verschlusskrankheiten |
US20060161001A1 (en) * | 2004-12-20 | 2006-07-20 | Amgen Inc. | Substituted heterocyclic compounds and methods of use |
PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
KR20080095902A (ko) | 2006-02-14 | 2008-10-29 | 버텍스 파마슈티칼스 인코포레이티드 | 단백질 키나제의 억제제로서 유용한 디하이드로디아제핀 |
AU2007227602A1 (en) * | 2006-03-16 | 2007-09-27 | Novartis Ag | Heterocyclic organic compounds for the treatment of in particular melanoma |
BRPI0811204A8 (pt) | 2007-05-10 | 2015-09-22 | Bristol Myers Squibb Co | Tetra-hidroibenzo-1,4-diazepinas substituídas por arila e heteroarila e uso das mesmas para bloquear a recaptação de norepinefrina, dopamina e serotonina |
BRPI0818338A2 (pt) * | 2007-10-16 | 2015-04-22 | Daiichi Sankyo Co Ltd | Composto de pirimidil indolina |
RU2012116526A (ru) | 2009-09-25 | 2013-10-27 | Вертекс Фармасьютикалз Инкорпорейтед | Способы получения производных пиримидина, применимых в качестве ингибиторов протеинкиназы |
RU2012116525A (ru) | 2009-09-25 | 2013-10-27 | Вертекс Фармасьютикалз Инкорпорейтед | Способы получения перемидиновых производных, пригодных в качестве ингибиторов протеинкиназ |
TWI513694B (zh) * | 2010-05-11 | 2015-12-21 | Amgen Inc | 抑制間變性淋巴瘤激酶的嘧啶化合物 |
KR101708761B1 (ko) * | 2012-04-13 | 2017-02-21 | 주식회사 머쉬메드 | 퓨린 유도체 또는 그의 염을 포함하는 아토피성 피부염의 예방 또는 치료용 조성물 |
WO2015054317A1 (en) | 2013-10-07 | 2015-04-16 | Kadmon Corporation, Llc | Rho kinase inhibitors |
WO2019000683A1 (zh) | 2017-06-30 | 2019-01-03 | 北京泰德制药股份有限公司 | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 |
US11390609B2 (en) | 2017-06-30 | 2022-07-19 | Beijing Tide Pharmaceutical Co., Ltd. | Rho-associated protein kinase inhibitor, pharmaceutical composition comprising same, and preparation method and use thereof |
ES2930804T3 (es) | 2017-06-30 | 2022-12-22 | Beijing Tide Pharmaceutical Co Ltd | Inhibidor de proteína cinasa asociada a RHO, composición farmacéutica que lo comprende, así como método de preparación y uso del mismo |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9523675D0 (en) * | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
EP0837063A1 (en) * | 1996-10-17 | 1998-04-22 | Pfizer Inc. | 4-Aminoquinazoline derivatives |
GB9905075D0 (en) * | 1999-03-06 | 1999-04-28 | Zeneca Ltd | Chemical compounds |
-
2000
- 2000-11-09 AP APAP/P/2002/002530A patent/AP2002002530A0/en unknown
- 2000-11-09 ES ES00971650T patent/ES2253266T3/es not_active Expired - Lifetime
- 2000-11-09 EE EEP200200275A patent/EE200200275A/xx unknown
- 2000-11-09 CA CA002392971A patent/CA2392971C/en not_active Expired - Fee Related
- 2000-11-09 CN CN00816506A patent/CN1402720A/zh active Pending
- 2000-11-09 EA EA200200411A patent/EA200200411A1/ru unknown
- 2000-11-09 AU AU10476/01A patent/AU1047601A/en not_active Abandoned
- 2000-11-09 DE DE60025385T patent/DE60025385T2/de not_active Expired - Lifetime
- 2000-11-09 KR KR1020027006941A patent/KR20020059826A/ko not_active Application Discontinuation
- 2000-11-09 CZ CZ20021703A patent/CZ20021703A3/cs unknown
- 2000-11-09 AT AT00971650T patent/ATE315036T1/de not_active IP Right Cessation
- 2000-11-09 TR TR2002/01431T patent/TR200201431T2/xx unknown
- 2000-11-09 HU HU0203300A patent/HUP0203300A3/hu unknown
- 2000-11-09 OA OA1200200156A patent/OA12097A/en unknown
- 2000-11-09 JP JP2001541899A patent/JP3955468B2/ja not_active Expired - Fee Related
- 2000-11-09 BR BR0015995-6A patent/BR0015995A/pt not_active Application Discontinuation
- 2000-11-09 MX MXPA02005350A patent/MXPA02005350A/es active IP Right Grant
- 2000-11-09 PL PL00355946A patent/PL355946A1/xx not_active Application Discontinuation
- 2000-11-09 EP EP00971650A patent/EP1242403B1/en not_active Expired - Lifetime
- 2000-11-09 WO PCT/IB2000/001628 patent/WO2001040215A1/en active IP Right Grant
- 2000-11-09 IL IL14910300A patent/IL149103A0/xx unknown
- 2000-11-22 PA PA20008506801A patent/PA8506801A1/es unknown
- 2000-11-23 HN HN2000000264A patent/HN2000000264A/es unknown
- 2000-11-28 UY UY26455A patent/UY26455A1/es not_active Application Discontinuation
- 2000-11-28 PE PE2000001268A patent/PE20010900A1/es not_active Application Discontinuation
- 2000-11-29 SV SV2000000231A patent/SV2002000231A/es unknown
- 2000-11-29 TN TNTNSN00232A patent/TNSN00232A1/fr unknown
- 2000-11-29 GT GT200000200A patent/GT200000200A/es unknown
- 2000-11-30 CO CO00091745A patent/CO5261519A1/es unknown
-
2002
- 2002-04-12 IS IS6339A patent/IS6339A/is unknown
- 2002-05-13 BG BG106695A patent/BG106695A/bg unknown
- 2002-05-28 MA MA26655A patent/MA26846A1/fr unknown
- 2002-05-29 NO NO20022557A patent/NO20022557D0/no not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20022557L (no) | 2,4-diaminopyrimidinforbindelser nyttige som immunosuppreserende midler | |
RS51607B (sr) | Novi lekovi za tretiranje hroničnog opstruktivnog oboljenja pluća | |
NO944911L (no) | Ikke-peptid-takykininreseptorantagonister | |
NO20074698L (no) | Pyrazinylsubstituerte piperazinpiperidiner med CXCR3-antagonistaktivitet | |
TW200640906A (en) | Heteroaryl substituted pyrazinyl-piperazine-piperidines with CXCR3 antagonist activity | |
HUP0300616A2 (hu) | Adamantánszármazékok, eljárás az előállításukra, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények | |
NZ325449A (en) | Naphthyl-substituted benzimidazole derivatives as anticoagulants | |
TW347387B (en) | Piperidine derivatives | |
AR023823A1 (es) | Compuestos derivados de piperazina utiles como antagonistas ccr5, composiciones farmaceuticas que los comprenden, y el uso de los mismos para la preparacion de medicamentos. | |
BR0212108A (pt) | Derivados de piperidina úteis como antagonistas de ccr5 | |
ATE378332T1 (de) | Benzofuranderivate,verfahren zu deren herstellung und zwischenprodukte davon | |
ATE208772T1 (de) | Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung | |
HUP0300618A2 (hu) | Adamantánszármazékok, eljárás az előállításukra, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények | |
DE60335911D1 (de) | Isochinolinonderivate und deren verwendung als medikamente | |
ATE269305T1 (de) | 1,4-disubstituierte piperidinderivate | |
CA2146429A1 (en) | 25-carboxylic acid derivatives in the vitamin d series, method of producing them, intermediate products for this method, pharmaceutical preparations containing these derivatives and their use in the manufacture of medicines | |
ATE218581T1 (de) | Cyclosporinderivat, dessen herstellung und pharmazeutische zusammensetzung | |
NO960653L (no) | Nytt, farmasöytisk middel for oral administrering omfattende progesteron og en polyetylenglykol sammen med en eksipiens | |
NO964667L (no) | Purin-6-on-derivater | |
NO20062491L (no) | Benzoksazinderivter og deres anvendelse | |
TR200000223T2 (tr) | XA faktörünü engelleyen heterosiklik türevler | |
IL158384A0 (en) | Treatment or prophylaxis of insulin producing cell graft rejection | |
NO961000L (no) | Piperidinderivater, fremgangsmåte for fremstilling derav og medikament og preparat inneholdende slike | |
HUP9900927A2 (hu) | Allergiás betegségek kezelésére alkalmas, szubsztituált 4-(1H-benzimidazol-2-il-amino)-piperidinek | |
NO20050903L (no) | Nye piperazinyl-pyrazinonderivater for behandling av 5HT-2A reseptorrelaterte forstyrrelser |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |