NO20021823D0 - Behandling av emfysem ved bruk av RAR-selektive retinoidagonister - Google Patents

Behandling av emfysem ved bruk av RAR-selektive retinoidagonister

Info

Publication number
NO20021823D0
NO20021823D0 NO20021823A NO20021823A NO20021823D0 NO 20021823 D0 NO20021823 D0 NO 20021823D0 NO 20021823 A NO20021823 A NO 20021823A NO 20021823 A NO20021823 A NO 20021823A NO 20021823 D0 NO20021823 D0 NO 20021823D0
Authority
NO
Norway
Prior art keywords
rar
emphysema
treatment
retinoid agonists
selective retinoid
Prior art date
Application number
NO20021823A
Other languages
English (en)
Other versions
NO328738B1 (no
NO20021823L (no
Inventor
Paula Nanette Belloni
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20021823D0 publication Critical patent/NO20021823D0/no
Publication of NO20021823L publication Critical patent/NO20021823L/no
Publication of NO328738B1 publication Critical patent/NO328738B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20021823A 1999-10-19 2002-04-18 Anvendelse av RAR-agonist for fremstilling av medikamenter. NO328738B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16041599P 1999-10-19 1999-10-19
PCT/EP2000/010076 WO2001030326A1 (en) 1999-10-19 2000-10-13 Treatment of emphysema using rar selective retinoid agonists

Publications (3)

Publication Number Publication Date
NO20021823D0 true NO20021823D0 (no) 2002-04-18
NO20021823L NO20021823L (no) 2002-04-18
NO328738B1 NO328738B1 (no) 2010-05-03

Family

ID=22576814

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20021823A NO328738B1 (no) 1999-10-19 2002-04-18 Anvendelse av RAR-agonist for fremstilling av medikamenter.

Country Status (34)

Country Link
US (1) US6300350B1 (no)
EP (1) EP1225878B1 (no)
JP (2) JP4074458B2 (no)
KR (1) KR100485581B1 (no)
CN (1) CN1201730C (no)
AR (1) AR029648A1 (no)
AT (1) ATE344661T1 (no)
AU (1) AU777325B2 (no)
BR (1) BR0015225A (no)
CA (1) CA2387844C (no)
CY (1) CY1105941T1 (no)
CZ (1) CZ20021657A3 (no)
DE (1) DE60031790T2 (no)
DK (1) DK1225878T3 (no)
ES (1) ES2274810T3 (no)
HK (1) HK1051002A1 (no)
HR (1) HRP20020329A2 (no)
HU (1) HUP0203295A3 (no)
IL (1) IL149151A0 (no)
JO (1) JO2178B1 (no)
MA (1) MA26835A1 (no)
MX (1) MXPA02003843A (no)
MY (1) MY129001A (no)
NO (1) NO328738B1 (no)
NZ (1) NZ518118A (no)
PE (1) PE20010678A1 (no)
PL (1) PL357499A1 (no)
PT (1) PT1225878E (no)
RS (1) RS50165B (no)
RU (1) RU2257383C2 (no)
TR (1) TR200201071T2 (no)
TW (1) TWI288639B (no)
WO (1) WO2001030326A1 (no)
ZA (1) ZA200202576B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4228000A (en) * 1999-04-14 2000-11-14 Allergan Sales, Inc. Methods and compositions for the treatment and prevention of lung disease
MXPA04002590A (es) * 2001-09-18 2004-06-18 Hoffmann La Roche Agonistas retinoides i de alquil urea.
ES2325063T3 (es) 2001-09-18 2009-08-25 F. Hoffmann-La Roche Ag Agonistas de retinoide ii de urea sustituida.
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
DK1656026T3 (da) 2003-08-22 2014-07-14 Dupont Nutrition Biosci Aps Sammensætning, der omfatter et bakteriocin og et ekstrakt fra en plante fra læbeblomstfamilien
GB2388581A (en) 2003-08-22 2003-11-19 Danisco Coated aqueous beads
US20100076037A1 (en) * 2006-11-02 2010-03-25 Chiang Lillian W Methods of Treating Neuropathic Pain with Agonists of PPAR-gamma
JP5986570B2 (ja) 2010-09-01 2016-09-06 トーマス・ジェファーソン・ユニバーシティＴｈｏｍａｓ Ｊｅｆｆｅｒｓｏｎ Ｕｎｉｖｅｒｓｉｔｙ 筋修復および再生のための組成物および方法
EP3616701A1 (en) 2011-06-24 2020-03-04 GRI Bio, Inc. Prevention and treatment of inflammatory conditions
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
WO2013019653A1 (en) * 2011-07-29 2013-02-07 Tempero Pharmaceuticals, Inc. Compounds and methods
AU2013363215B2 (en) 2012-12-17 2018-03-01 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
AP2015008556A0 (en) 2012-12-17 2015-06-30 Parion Sciences Inc Chloro-pyrazine carboxamide derivatives useful forthe treatment of diseases favoured by insufficien t mucosal hydration
ES2909884T3 (es) 2013-08-20 2022-05-10 Univ Washington Through Its Center For Commercialization Inhibidores nuevos y específicos de la hidroxilasa del ácido retinoico del citocromo P450 26
WO2015041809A2 (en) 2013-08-26 2015-03-26 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Small molecule cellular reprogramming to generate neuronal cells
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0139216B1 (ko) 1988-04-11 1998-05-01 제임스 엠. 캐내지 레티노이드 유사활성을 갖는 페놀 또는 벤조산의 테트랄린 에스테르
CA2129773C (en) * 1993-09-02 2007-05-01 Michael Klaus Aromatic carboxylic acid derivatives
US5498795A (en) * 1994-12-29 1996-03-12 Allergan, Inc. Acetylenes disubstituted with hydroxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
US5807900A (en) * 1995-03-31 1998-09-15 Hoffmann-La Roche, Inc. Method for identifying compounds having increased activity for the repair of skin photodamage
US5624957A (en) * 1995-06-06 1997-04-29 Bristol-Myers Squibb Company Rary-specific retinobenzoic acid derivatives
FR2739557B1 (fr) * 1995-10-09 1997-11-14 Cird Galderma Utilisation d'un ligand agoniste specifique rar-gamma
US5726191A (en) 1995-11-16 1998-03-10 Hoffmann-La Roche Inc. Aromatic carboxylic acid esters
FR2747041B1 (fr) 1996-04-05 1998-05-22 Cird Galderma Utilisation de derives benzonaphtaleniques pour la fabrication de medicaments destines au traitement des neuropathies
KR100440836B1 (ko) * 1997-11-12 2004-07-19 에프. 호프만-라 로슈 아게 레티노이드 길항제를 이용한 제2형 ｔ-보조세포 중재 면역질환의 치료
US6083973A (en) * 1998-03-09 2000-07-04 Syntex (U.S.A.) Inc. Methods for inhibiting mucin secretion using RAR α selective antagonists
AU4228000A (en) * 1999-04-14 2000-11-14 Allergan Sales, Inc. Methods and compositions for the treatment and prevention of lung disease
AU4225500A (en) * 1999-04-14 2000-11-14 Allergan Sales, Inc. Methods and compositions for the treatment and prevention of lung disease
WO2000061182A2 (en) 1999-04-14 2000-10-19 Allergan Sales, Inc. Methods and compositions for the treatment and prevention of lung disease involving a selective rar-alpha agonist
KR100466730B1 (ko) * 1999-08-02 2005-01-24 에프. 호프만-라 로슈 아게 신규한 선택적 레티노이드 작용물질
US6479670B1 (en) * 1999-08-25 2002-11-12 Hoffmann-La Roche Inc. Selective retinoid acid receptor agonists

Also Published As

Publication number Publication date
TWI288639B (en) 2007-10-21
DK1225878T3 (da) 2007-03-05
CZ20021657A3 (cs) 2002-10-16
CA2387844C (en) 2009-04-14
CA2387844A1 (en) 2001-05-03
JP2007302689A (ja) 2007-11-22
RS50165B (sr) 2009-05-06
PL357499A1 (en) 2004-07-26
HUP0203295A2 (hu) 2003-01-28
MY129001A (en) 2007-03-30
ZA200202576B (en) 2003-09-23
ES2274810T3 (es) 2007-06-01
HRP20020329A2 (en) 2004-04-30
ATE344661T1 (de) 2006-11-15
US6300350B1 (en) 2001-10-09
CY1105941T1 (el) 2011-04-06
RU2257383C2 (ru) 2005-07-27
CN1382042A (zh) 2002-11-27
MXPA02003843A (es) 2002-09-30
HUP0203295A3 (en) 2003-04-28
JP2003512418A (ja) 2003-04-02
TR200201071T2 (tr) 2002-08-21
PT1225878E (pt) 2007-01-31
KR20020043640A (ko) 2002-06-10
DE60031790D1 (de) 2006-12-21
PE20010678A1 (es) 2001-07-04
NO328738B1 (no) 2010-05-03
JP4074458B2 (ja) 2008-04-09
AR029648A1 (es) 2003-07-10
NO20021823L (no) 2002-04-18
WO2001030326A1 (en) 2001-05-03
EP1225878B1 (en) 2006-11-08
MA26835A1 (fr) 2004-12-20
JO2178B1 (en) 2003-04-23
DE60031790T2 (de) 2007-09-20
IL149151A0 (en) 2002-11-10
BR0015225A (pt) 2002-07-16
KR100485581B1 (ko) 2005-04-27
NZ518118A (en) 2004-02-27
CN1201730C (zh) 2005-05-18
JP4850791B2 (ja) 2012-01-11
HK1051002A1 (en) 2003-07-18
EP1225878A1 (en) 2002-07-31
AU1137401A (en) 2001-05-08
YU29002A (sh) 2005-06-10
AU777325B2 (en) 2004-10-14

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