NO20011417L - [1,2,4]triazolo[1,5-c]pyrimidin-derivater - Google Patents

[1,2,4]triazolo[1,5-c]pyrimidin-derivater

Info

Publication number
NO20011417L
NO20011417L NO20011417A NO20011417A NO20011417L NO 20011417 L NO20011417 L NO 20011417L NO 20011417 A NO20011417 A NO 20011417A NO 20011417 A NO20011417 A NO 20011417A NO 20011417 L NO20011417 L NO 20011417L
Authority
NO
Norway
Prior art keywords
represent
triazolo
aryl
pyrimidine derivatives
lower alkyl
Prior art date
Application number
NO20011417A
Other languages
English (en)
Other versions
NO20011417D0 (no
Inventor
Junichi Shimada
Hironori Imma
Naoto Osakada
Shizuo Shiozaki
Tomoyuki Kanda
Yoshihisa Kuwana
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of NO20011417D0 publication Critical patent/NO20011417D0/no
Publication of NO20011417L publication Critical patent/NO20011417L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20011417A 1998-09-22 2001-03-20 [1,2,4]triazolo[1,5-c]pyrimidin-derivater NO20011417L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26717898 1998-09-22
PCT/JP1999/005176 WO2000017201A1 (fr) 1998-09-22 1999-09-22 DERIVES DE [1,2,4]TRIAZOLO[1,5-c]PYRIMIDINE

Publications (2)

Publication Number Publication Date
NO20011417D0 NO20011417D0 (no) 2001-03-20
NO20011417L true NO20011417L (no) 2001-05-21

Family

ID=17441200

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011417A NO20011417L (no) 1998-09-22 2001-03-20 [1,2,4]triazolo[1,5-c]pyrimidin-derivater

Country Status (15)

Country Link
US (1) US6545000B1 (no)
EP (1) EP1116722B1 (no)
KR (1) KR20010087361A (no)
CN (1) CN1328560A (no)
AT (1) ATE286900T1 (no)
AU (1) AU756144B2 (no)
BR (1) BR9914040A (no)
CA (1) CA2344828A1 (no)
DE (1) DE69923197T2 (no)
EA (1) EA200100265A1 (no)
HU (1) HUP0103921A3 (no)
IL (1) IL142128A0 (no)
NO (1) NO20011417L (no)
NZ (1) NZ510629A (no)
WO (1) WO2000017201A1 (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002079204A1 (fr) * 2001-03-28 2002-10-10 Kyowa Hakko Kogyo Co., Ltd. Derive 8-thiazolyl[1,2,4]triazolo[1,5-c]pyrimidine
JP5280597B2 (ja) * 2001-03-30 2013-09-04 サンスター技研株式会社 一液加熱硬化型エポキシ樹脂組成物および半導体実装用アンダーフィル材
EP1425017A1 (en) * 2001-09-13 2004-06-09 Schering Corporation Combination of an adenosine a2a receptor antagonist and an antidepressant or anxiolytic
US6875772B2 (en) * 2001-11-30 2005-04-05 Schering Corporation [1,2,4]-Triazole bicyclic adeonsine A2a receptor antagonists
AR038366A1 (es) * 2001-11-30 2005-01-12 Schering Corp Compuestos de 1,2,4-triazolo [1,5-c] pirimidinas sustituidas, antagonistas del receptor de adenosina a2a, composiciones farmaceuticas, el uso de dichos compuestos para la manufactura de un medicamento para el tratamiento de enfermedades del sistema nervioso central y un kit que comprende combinacion
US6734179B2 (en) 2001-12-12 2004-05-11 Hoffmann-La Roche Inc. Benzothiazoles
BR0214936A (pt) * 2001-12-12 2004-12-14 Hoffmann La Roche Benzotiofenos como moduladores do receptor de adenosina
ES2716404T3 (es) 2002-01-28 2019-06-12 Kyowa Hakko Kogyo Kk Antagonistas de receptores A2A para su uso en el tratamiento de trastornos del movimiento
AU2003211993A1 (en) * 2002-02-15 2003-09-04 Kyowa Hakko Kogyo Co., Ltd. (1,2,4)TRIAZOLO(1,5-c)PYRIMIDINE DERIVATIVES
CA2500228A1 (en) * 2002-09-24 2004-04-08 Kyowa Hakko Kogyo Co., Ltd. [1,2,4]-triazolo[1,5-c]pyrimidine derivative
WO2004092170A2 (en) 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists
WO2004092177A1 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolopyrazines and methods of making and using the same
ATE418555T1 (de) 2003-04-09 2009-01-15 Biogen Idec Inc A2a-adenosinrezeptorantagonisten
US20070010522A1 (en) * 2003-04-09 2007-01-11 Chi Vu Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosine receptor antagonists
CN1787821A (zh) * 2003-06-10 2006-06-14 协和发酵工业株式会社 一种治疗焦虑症的方法
ATE556712T1 (de) * 2005-06-07 2012-05-15 Kyowa Hakko Kirin Co Ltd A2a antagonisten zur behandlung von motorischen störungen
US7994190B2 (en) 2006-11-01 2011-08-09 Bristol-Myers Squibb Company Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
TWI473614B (zh) 2008-05-29 2015-02-21 Kyowa Hakko Kirin Co Ltd Anti-analgesic inhibitors
WO2010010908A1 (ja) * 2008-07-23 2010-01-28 協和発酵キリン株式会社 片頭痛治療剤
WO2010111626A2 (en) * 2009-03-27 2010-09-30 Takeda Pharmaceutical Company Limited Poly (adp-ribose) polymerase (parp) inhibitors
CN109963854B (zh) * 2017-03-16 2022-04-12 江苏恒瑞医药股份有限公司 杂芳基并[4,3-c]嘧啶-5-胺类衍生物、其制备方法及其在医药上的应用
WO2019168847A1 (en) 2018-02-27 2019-09-06 Incyte Corporation Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors
EP3810610A1 (en) 2018-05-18 2021-04-28 Incyte Corporation Fused pyrimidine derivatives as a2a / a2b inhibitors
KR20210049090A (ko) 2018-07-05 2021-05-04 인사이트 코포레이션 A2a/a2b 억제제로서 융합된 피라진 유도체
CN110903291B (zh) * 2018-09-14 2021-09-03 江苏恒瑞医药股份有限公司 一种杂芳基并[4,3-c]嘧啶-5-胺类衍生物的盐、盐的晶型及制备方法
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572910A (en) 1983-03-03 1986-02-25 Riker Laboratories, Inc. Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing heterocyclic rings
US4477450A (en) 1983-03-03 1984-10-16 Riker Laboratories, Inc. Triazolo [4,3-c]pyrimidines substituted by nitrogen-containing heterocyclic rings
US4483987A (en) 1983-06-20 1984-11-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides
NZ208996A (en) 1983-07-28 1989-08-29 American Cyanamid Co 5-substituted(1,2,4 triazpyrimidin-2-amine derivatives and pharmaceutical compositions
US5356894A (en) 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
EP0459702A1 (en) 1990-05-29 1991-12-04 Zeneca Limited Azole Derivatives
EP0667349B1 (en) * 1993-09-06 2001-01-24 Kyowa Hakko Kogyo Kabushiki Kaisha Depression remedy
ATE257156T1 (de) * 1997-03-24 2004-01-15 Kyowa Hakko Kogyo Kk (1,2,4)triazolo(1,5-c)pyrimidin-derivate

Also Published As

Publication number Publication date
EP1116722B1 (en) 2005-01-12
US6545000B1 (en) 2003-04-08
AU5757999A (en) 2000-04-10
EP1116722A1 (en) 2001-07-18
AU756144B2 (en) 2003-01-02
CN1328560A (zh) 2001-12-26
DE69923197T2 (de) 2005-12-29
IL142128A0 (en) 2002-03-10
WO2000017201A1 (fr) 2000-03-30
DE69923197D1 (de) 2005-02-17
ATE286900T1 (de) 2005-01-15
HUP0103921A2 (hu) 2002-04-29
CA2344828A1 (en) 2000-03-30
NZ510629A (en) 2003-04-29
EA200100265A1 (ru) 2001-10-22
KR20010087361A (ko) 2001-09-15
NO20011417D0 (no) 2001-03-20
BR9914040A (pt) 2002-01-15
EP1116722A4 (en) 2002-05-29
HUP0103921A3 (en) 2002-12-28

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application