ES2055211T3 - Purinil- y pirimidinil-tetrahidrofuranos. - Google Patents

Purinil- y pirimidinil-tetrahidrofuranos.

Info

Publication number
ES2055211T3
ES2055211T3 ES90107615T ES90107615T ES2055211T3 ES 2055211 T3 ES2055211 T3 ES 2055211T3 ES 90107615 T ES90107615 T ES 90107615T ES 90107615 T ES90107615 T ES 90107615T ES 2055211 T3 ES2055211 T3 ES 2055211T3
Authority
ES
Spain
Prior art keywords
tetrahidrofuranos
purinil
pirimidinil
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90107615T
Other languages
English (en)
Inventor
Robert Zahler
Joseph Anthony Tino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of ES2055211T3 publication Critical patent/ES2055211T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

LOS COMPUESTOS DE LA FORMULA PRESENTAN ACTIVIDAD ANTIVIRAL Y SALES FARMACEUTICAMENTE ACEPTABLES EN DONDE R1 ES UNA BASE DE PURINA O PIRIMIDINA O SU ANALOGO, Y R2 Y R3 SON INDEPENDIENTEMENTE HIDROGENO, -PO3H2 O -C-X7, EN ONDE X7 ES HIDROGENO, ALQUILO, ALQUILO SUSTITUIDO O ARILO.
ES90107615T 1989-04-24 1990-04-23 Purinil- y pirimidinil-tetrahidrofuranos. Expired - Lifetime ES2055211T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34204889A 1989-04-24 1989-04-24

Publications (1)

Publication Number Publication Date
ES2055211T3 true ES2055211T3 (es) 1994-08-16

Family

ID=23340115

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90107615T Expired - Lifetime ES2055211T3 (es) 1989-04-24 1990-04-23 Purinil- y pirimidinil-tetrahidrofuranos.

Country Status (13)

Country Link
EP (1) EP0394893B1 (es)
JP (1) JP2780843B2 (es)
AT (1) ATE107929T1 (es)
AU (2) AU616839B2 (es)
CA (1) CA2012851C (es)
DE (1) DE69010262T2 (es)
DK (1) DK0394893T3 (es)
ES (1) ES2055211T3 (es)
HU (1) HU207080B (es)
IE (1) IE66509B1 (es)
NZ (1) NZ232993A (es)
PT (1) PT93852B (es)
ZA (1) ZA902321B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ232993A (en) * 1989-04-24 1992-10-28 Squibb & Sons Inc Purinyl and pyrimidinyl tetrahydrofurans
ZA914894B (en) * 1990-07-02 1992-04-29 Squibb & Sons Inc Purinyl and pyrimidinyl tetrahydrofurans
US5272152A (en) * 1990-07-02 1993-12-21 E. R. Squibb & Sons, Inc. Purinyl and pyrimidinyl tetrahydrofurans
CZ134893A3 (en) * 1992-07-08 1994-02-16 Hoechst Ag Aromatic copolyamides, process of their preparation and objects made therefrom
JPH06263756A (ja) * 1993-03-04 1994-09-20 Asahi Breweries Ltd イソヌクレオシド誘導体
DE4327595A1 (de) * 1993-08-17 1995-02-23 Hoechst Ag Zusammensetzungen mit verbesserten elektrostatischen Eigenschaften enthaltend aromatische Polyamide, daraus hergestellte geformte Gebilde sowie deren Verwendung und Verfahren zu ihrer Herstellung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU192741B (en) * 1978-05-25 1987-07-28 Toyo Jozo Kk Process for producing new neplanocin antibiotics
DK363987A (da) * 1986-08-08 1988-02-09 Hoffmann La Roche Pyrimidinderivater
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
IL85778A0 (en) * 1987-03-20 1988-09-30 Bristol Myers Co Production of 2',3'-dideoxynucleosides and certain such novel compounds
WO1988007532A1 (en) * 1987-03-24 1988-10-06 Nycomed A.S. 2',3' dideoxyribofuranoxide derivatives
US4855466A (en) * 1987-12-28 1989-08-08 E. R. Squibb & Sons, Inc. Purinyl cyclobutanes
US5723609A (en) * 1988-03-30 1998-03-03 E. R. Squibb & Sons, Inc. Bis (hydroxymethyl) cyclobutyl purines
GB8814340D0 (en) * 1988-06-16 1988-07-20 Ici Plc Process
NZ232993A (en) * 1989-04-24 1992-10-28 Squibb & Sons Inc Purinyl and pyrimidinyl tetrahydrofurans

Also Published As

Publication number Publication date
EP0394893B1 (en) 1994-06-29
CA2012851A1 (en) 1990-10-24
AU623304B2 (en) 1992-05-07
ATE107929T1 (de) 1994-07-15
AU616839B2 (en) 1991-11-07
AU8263391A (en) 1991-10-24
NZ232993A (en) 1992-10-28
ZA902321B (en) 1990-12-28
DE69010262T2 (de) 1995-02-09
DK0394893T3 (da) 1994-07-25
JPH02295989A (ja) 1990-12-06
PT93852B (pt) 1996-08-30
HU902531D0 (en) 1990-08-28
HUT54153A (en) 1991-01-28
PT93852A (pt) 1990-11-20
EP0394893A2 (en) 1990-10-31
EP0394893A3 (en) 1991-05-15
JP2780843B2 (ja) 1998-07-30
DE69010262D1 (de) 1994-08-04
IE901291L (en) 1990-10-24
HU207080B (en) 1993-03-01
IE66509B1 (en) 1996-01-10
AU5222590A (en) 1990-10-25
CA2012851C (en) 2000-07-11

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