NO20005989L - 17<beta>-amino og hydroksylamino-11<beta>-arylsteroider og deres derivater som har agonist eller antagonisthormonelle egenskaper - Google Patents

17<beta>-amino og hydroksylamino-11<beta>-arylsteroider og deres derivater som har agonist eller antagonisthormonelle egenskaper

Info

Publication number
NO20005989L
NO20005989L NO20005989A NO20005989A NO20005989L NO 20005989 L NO20005989 L NO 20005989L NO 20005989 A NO20005989 A NO 20005989A NO 20005989 A NO20005989 A NO 20005989A NO 20005989 L NO20005989 L NO 20005989L
Authority
NO
Norway
Prior art keywords
beta
hydroxylamino
agonist
derivatives
amino
Prior art date
Application number
NO20005989A
Other languages
English (en)
Other versions
NO317988B1 (no
NO20005989D0 (no
Inventor
Edgar C Cook
John A Kepler
Gary S Bartley
Rupa S Shetty
Original Assignee
Res Triangle Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Triangle Inst filed Critical Res Triangle Inst
Publication of NO20005989L publication Critical patent/NO20005989L/no
Publication of NO20005989D0 publication Critical patent/NO20005989D0/no
Publication of NO317988B1 publication Critical patent/NO317988B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20005989A 1998-05-29 2000-11-27 17<beta>-amino og hydroksylamino-11<beta>-arylsteroider og deres derivater som har agonist eller antagonisthormonelle egenskaper og fremgangsmate for fremstilling av samme NO317988B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/086,560 US6262042B1 (en) 1998-05-29 1998-05-29 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
PCT/US1999/010480 WO1999062928A1 (en) 1998-05-29 1999-05-28 17β-AMINO AND HYDROXYLAMINO-11β-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES

Publications (3)

Publication Number Publication Date
NO20005989L true NO20005989L (no) 2000-11-27
NO20005989D0 NO20005989D0 (no) 2000-11-27
NO317988B1 NO317988B1 (no) 2005-01-17

Family

ID=22199388

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005989A NO317988B1 (no) 1998-05-29 2000-11-27 17<beta>-amino og hydroksylamino-11<beta>-arylsteroider og deres derivater som har agonist eller antagonisthormonelle egenskaper og fremgangsmate for fremstilling av samme

Country Status (25)

Country Link
US (3) US6262042B1 (no)
EP (1) EP1082337B1 (no)
JP (1) JP4545929B2 (no)
KR (1) KR100611289B1 (no)
CN (1) CN100357311C (no)
AT (1) ATE333462T1 (no)
AU (1) AU753382B2 (no)
BR (1) BR9910794A (no)
CA (1) CA2333669C (no)
CY (1) CY1106443T1 (no)
CZ (1) CZ300313B6 (no)
DE (1) DE69932432T8 (no)
DK (1) DK1082337T3 (no)
ES (1) ES2270596T3 (no)
HK (1) HK1035196A1 (no)
HU (1) HU228770B1 (no)
ID (1) ID26885A (no)
IL (1) IL139861A (no)
NO (1) NO317988B1 (no)
NZ (1) NZ507985A (no)
PL (1) PL198055B1 (no)
PT (1) PT1082337E (no)
RU (1) RU2238943C2 (no)
SK (1) SK285748B6 (no)
WO (1) WO1999062928A1 (no)

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US6262042B1 (en) * 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
ES2190373B1 (es) * 2001-12-07 2004-10-16 J. URIACH &amp; CIA, S.A. Uso del acido 2-hidroxi- o 2-acetiloxi-4-trifluorometilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero.
WO2004081002A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7208486B2 (en) 2003-03-07 2007-04-24 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US8097606B2 (en) * 2003-07-23 2012-01-17 Corcept Therapeutics, Inc. Antiglucocorticoids for the treatment of catatonia
US20070249573A1 (en) * 2006-04-13 2007-10-25 Gerd Schubert 17alpha-substituted 4-(3-oxoestra-4,9-dien-11beta-yl)-benzoic acid, its derivatives and process for its production
US9517240B2 (en) 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
US20100160275A1 (en) * 2006-09-26 2010-06-24 Lee Eva Y H P Methods and compositions for cancer prevention and treatment
US8299050B2 (en) * 2008-01-29 2012-10-30 Laboratoire Hra-Pharma Method for treating uterine fibroids
US8778969B2 (en) * 2009-11-07 2014-07-15 Peter H Proctor Nitrone, nitroso, and nitroxide spintraps and spin labels and their hydroxylamines
US9096641B2 (en) * 2013-06-05 2015-08-04 Evestra, Inc. Imidazolyl progesterone antagonists

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DE287510C (no)
DE290198C (no)
US3187022A (en) * 1964-01-31 1965-06-01 Parke Davis & Co 17beta-amino-17alpha-pregnen-20-one compounds and the production thereof
US4686085A (en) * 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
ZA8231B (en) 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (fr) 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
DE3306121A1 (de) * 1983-02-18 1984-09-06 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-spirolaktone in der steroidreihe, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische praeparate
EP0116974B1 (de) * 1983-02-18 1986-10-29 Schering Aktiengesellschaft 11-Beta-Aryl-Estradiene, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE3347126A1 (de) 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
US4481144A (en) 1984-02-03 1984-11-06 E. R. Squibb & Sons, Inc. 17-Substituted thia-17-alkyl(or alkenyl or alkynyl)androstenes
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AU580843B2 (en) 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
DE3506785A1 (de) 1985-02-22 1986-08-28 Schering AG, Berlin und Bergkamen, 1000 Berlin 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2596395B1 (fr) 1986-03-26 1989-05-26 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2598421B1 (fr) 1986-05-06 1988-08-19 Roussel Uclaf Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
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FR2618783B1 (fr) 1987-07-30 1991-02-01 Roussel Uclaf Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
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FR2643638B1 (fr) 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
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DE4042005A1 (de) 1990-12-22 1992-06-25 Schering Ag D-homo-(16-en)-11(beta)-aryl-4-estrene
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US5962444A (en) 1998-05-29 1999-10-05 Research Triangle Institute 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US6262042B1 (en) * 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US6172052B1 (en) 1998-12-04 2001-01-09 Research Triangle Institute 17β-acyl-17α-propynyl-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
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Also Published As

Publication number Publication date
HU228770B1 (en) 2013-05-28
CA2333669C (en) 2008-08-26
EP1082337B1 (en) 2006-07-19
JP2002531381A (ja) 2002-09-24
KR100611289B1 (ko) 2006-08-10
JP4545929B2 (ja) 2010-09-15
US6262042B1 (en) 2001-07-17
DE69932432T2 (de) 2007-03-15
US7018991B2 (en) 2006-03-28
CY1106443T1 (el) 2011-10-12
DE69932432D1 (de) 2006-08-31
KR20010052427A (ko) 2001-06-25
IL139861A (en) 2005-09-25
EP1082337A4 (en) 2004-12-29
US20020065257A1 (en) 2002-05-30
DE69932432T8 (de) 2007-08-23
SK285748B6 (sk) 2007-07-06
AU4076199A (en) 1999-12-20
DK1082337T3 (da) 2006-12-04
ES2270596T3 (es) 2007-04-01
CZ20004446A3 (cs) 2001-04-11
US6620801B2 (en) 2003-09-16
HUP0103109A2 (hu) 2002-01-28
PL344413A1 (en) 2001-11-05
CN100357311C (zh) 2007-12-26
IL139861A0 (en) 2002-02-10
CA2333669A1 (en) 1999-12-09
ATE333462T1 (de) 2006-08-15
RU2238943C2 (ru) 2004-10-27
CZ300313B6 (cs) 2009-04-15
AU753382B2 (en) 2002-10-17
HK1035196A1 (en) 2001-11-16
BR9910794A (pt) 2001-02-13
SK18092000A3 (sk) 2001-04-09
WO1999062928A1 (en) 1999-12-09
NO317988B1 (no) 2005-01-17
NO20005989D0 (no) 2000-11-27
US20040023936A1 (en) 2004-02-05
NZ507985A (en) 2003-11-28
EP1082337A1 (en) 2001-03-14
HUP0103109A3 (en) 2002-09-30
PL198055B1 (pl) 2008-05-30
CN1303391A (zh) 2001-07-11
PT1082337E (pt) 2006-11-30
ID26885A (id) 2001-02-15

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