DK1135403T3 - 17beta-acyl-17alfa-propynyl-11beta-arylsteroider og deres derivater med agonistiske eller antagonistiske hormonale egenskaber - Google Patents

17beta-acyl-17alfa-propynyl-11beta-arylsteroider og deres derivater med agonistiske eller antagonistiske hormonale egenskaber

Info

Publication number
DK1135403T3
DK1135403T3 DK99964047T DK99964047T DK1135403T3 DK 1135403 T3 DK1135403 T3 DK 1135403T3 DK 99964047 T DK99964047 T DK 99964047T DK 99964047 T DK99964047 T DK 99964047T DK 1135403 T3 DK1135403 T3 DK 1135403T3
Authority
DK
Denmark
Prior art keywords
17beta
acyl
propynyl
11beta
17alpha
Prior art date
Application number
DK99964047T
Other languages
English (en)
Inventor
C Edgar Cook
John A Kepler
Jill M O'reilly
Original Assignee
Res Triangle Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Triangle Inst filed Critical Res Triangle Inst
Application granted granted Critical
Publication of DK1135403T3 publication Critical patent/DK1135403T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99964047T 1998-12-04 1999-12-03 17beta-acyl-17alfa-propynyl-11beta-arylsteroider og deres derivater med agonistiske eller antagonistiske hormonale egenskaber DK1135403T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/205,395 US6172052B1 (en) 1998-12-04 1998-12-04 17β-acyl-17α-propynyl-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
PCT/US1999/028535 WO2000034306A1 (en) 1998-12-04 1999-12-03 17β-ACYL-17α-PROPYNYL-11β-ARYLSTEROIDS AND THEIR DERIVATIVES HAVING AGONIST OR ANTAGONIST HORMONAL PROPERTIES

Publications (1)

Publication Number Publication Date
DK1135403T3 true DK1135403T3 (da) 2003-11-24

Family

ID=22762018

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99964047T DK1135403T3 (da) 1998-12-04 1999-12-03 17beta-acyl-17alfa-propynyl-11beta-arylsteroider og deres derivater med agonistiske eller antagonistiske hormonale egenskaber

Country Status (14)

Country Link
US (1) US6172052B1 (da)
EP (1) EP1135403B1 (da)
CN (1) CN1348461A (da)
AT (1) ATE246201T1 (da)
AU (1) AU777048B2 (da)
CA (1) CA2358466C (da)
DE (1) DE69910068T2 (da)
DK (1) DK1135403T3 (da)
ES (1) ES2203233T3 (da)
NZ (1) NZ512697A (da)
PT (1) PT1135403E (da)
RU (1) RU2230071C2 (da)
SI (1) SI1135403T1 (da)
WO (1) WO2000034306A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0900234T3 (da) 1996-05-01 2000-11-06 Us Gov Health & Human Serv 21-substituerede progesteronderivater anvendt som nye antigestagener
US6900193B1 (en) 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
US6262042B1 (en) 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
DK1265911T3 (da) * 2000-03-17 2008-09-29 Us Gov Health & Human Serv 17-alfa-substitueret-11-beta-substitueret-4-aryl og 21-substitueret 19-norpregnadiendion som antiprogestationelle midler
TWI477276B (zh) 2008-04-28 2015-03-21 Repros Therapeutics Inc 抗黃體素給藥方案
DE102009034362A1 (de) * 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
JP5894143B2 (ja) * 2010-03-22 2016-03-23 リプロス セラピューティクス インコーポレイテッド 抗黄体ホルモンの無毒送達のための組成物および方法
US20130029953A1 (en) * 2011-07-28 2013-01-31 Klaus Nickisch Progesterone antagonists
US9096641B2 (en) * 2013-06-05 2015-08-04 Evestra, Inc. Imidazolyl progesterone antagonists
EP2881638A1 (de) 2013-12-09 2015-06-10 HILTI Aktiengesellschaft Vorrichtung zur Durchführung von Rohren oder Kabeln durch eine Gebäudeföffnung
EP3088784A1 (de) 2015-04-27 2016-11-02 Hilti Aktiengesellschaft Brandschutzmanschette
EP3088783A1 (de) 2015-04-27 2016-11-02 Hilti Aktiengesellschaft Brandschutzmanschette
WO2023185673A1 (zh) * 2022-03-31 2023-10-05 成都赛璟生物医药科技有限公司 一种cdk8抑制剂及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047928A (en) * 1986-10-24 1991-09-10 Wiedemer John D Billing system for computer software
US4954490A (en) 1988-06-23 1990-09-04 Research Triangle Institute 11 β-substituted progesterone analogs
WO1991001958A2 (de) 1989-08-04 1991-02-21 Schering Aktiengesellschaft Berlin Und Bergkamen 11β-ARYL-GONA-4,9-DIEN-3-ONE
DE4000686A1 (de) * 1990-01-12 1991-07-18 Dornier Gmbh Lindauer Steg-ladensohle fuer eine greifer-webmaschine
FR2659233B1 (fr) 1990-03-06 1994-01-21 Roussel Uclaf Nouvelle utilisation de composes anti-progestomimetiques chez les animaux d'elevage.
US5407928A (en) 1990-08-15 1995-04-18 Schering Aktiengesellschaft 11β-aryl-gona-4,9-dien-3-ones
FR2757399B1 (fr) 1996-12-23 1999-12-17 Hoechst Marion Roussel Inc Application de composes steroides substitues en 11 pour la fabrication de medicaments ayant une activite estrogene dissociee
US6020328A (en) 1998-03-06 2000-02-01 Research Triangle Institute 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties

Also Published As

Publication number Publication date
CA2358466A1 (en) 2000-06-15
SI1135403T1 (en) 2004-02-29
CN1348461A (zh) 2002-05-08
US6172052B1 (en) 2001-01-09
ES2203233T3 (es) 2004-04-01
PT1135403E (pt) 2003-12-31
CA2358466C (en) 2008-04-15
DE69910068T2 (de) 2004-04-15
DE69910068D1 (de) 2003-09-04
RU2001118273A (ru) 2004-03-10
NZ512697A (en) 2003-01-31
WO2000034306A1 (en) 2000-06-15
EP1135403A1 (en) 2001-09-26
AU2036600A (en) 2000-06-26
EP1135403A4 (en) 2002-03-27
RU2230071C2 (ru) 2004-06-10
ATE246201T1 (de) 2003-08-15
AU777048B2 (en) 2004-09-30
EP1135403B1 (en) 2003-07-30

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