ATE377020T1 - Kristallines gamma-lacton der17beta-hydroxy- - Google Patents

Kristallines gamma-lacton der17beta-hydroxy-

Info

Publication number
ATE377020T1
ATE377020T1 AT03774488T AT03774488T ATE377020T1 AT E377020 T1 ATE377020 T1 AT E377020T1 AT 03774488 T AT03774488 T AT 03774488T AT 03774488 T AT03774488 T AT 03774488T AT E377020 T1 ATE377020 T1 AT E377020T1
Authority
AT
Austria
Prior art keywords
der17beta
lactone
hydroxy
crystalline gamma
gamma
Prior art date
Application number
AT03774488T
Other languages
English (en)
Inventor
Bruce Pearlman
Frederick Antosz
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Application granted granted Critical
Publication of ATE377020T1 publication Critical patent/ATE377020T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT03774488T 2002-09-19 2003-09-19 Kristallines gamma-lacton der17beta-hydroxy- ATE377020T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41187402P 2002-09-19 2002-09-19
US42559602P 2002-11-12 2002-11-12
US10/392,833 US7235655B2 (en) 2002-03-22 2003-03-21 Processes to prepare eplerenone

Publications (1)

Publication Number Publication Date
ATE377020T1 true ATE377020T1 (de) 2007-11-15

Family

ID=32180478

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03774488T ATE377020T1 (de) 2002-09-19 2003-09-19 Kristallines gamma-lacton der17beta-hydroxy-

Country Status (8)

Country Link
US (6) US7235655B2 (de)
EP (1) EP1539795B1 (de)
JP (1) JP2006505624A (de)
AT (1) ATE377020T1 (de)
AU (1) AU2003282868A1 (de)
DE (1) DE60317214T2 (de)
ES (1) ES2295663T3 (de)
WO (1) WO2004037844A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
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EP1490390A2 (de) * 2002-03-22 2004-12-29 Pharmacia Corporation C-17-spirolactonisierung und 6,7-oxidation von steroiden
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
CL2004000574A1 (es) * 2003-03-21 2005-02-11 Pharmacia Corp Sa Organizada B Proceso para preparar un compuesto 17-espirolactona o la sal de lactona abierta por carbonilacion del correspondiente 17-alquenil o alquinil derivado, los intermediarios que se usan y su proceso de obtencion.
US8110699B2 (en) * 2008-09-12 2012-02-07 University Of South Florida Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates
CN109071981B (zh) 2016-03-08 2022-10-11 3D系统公司 用于3d印刷的非异氰酸酯聚氨酯油墨
CN112980910B (zh) * 2021-03-19 2024-01-05 上海应用技术大学 一种在相转移催化剂体系中微生物转化11α-羟基坎利酮的方法

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DE69637140T2 (de) * 1995-12-11 2008-04-10 G.D. Searle Llc, Chicago Verfahren zur herstellung einer epoxy-verbindung
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US6638937B2 (en) * 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
UA74141C2 (uk) * 1998-12-09 2005-11-15 Дж.Д. Сірл Енд Ко. Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти)
JP2003516414A (ja) 1999-12-08 2003-05-13 ファルマシア コーポレイション より高い溶解速度を示すエプレレノン結晶形
EP1175434A2 (de) 1999-12-08 2002-01-30 Pharmacia Corporation Kristalline form von eplerenon
US6444813B2 (en) * 2000-02-02 2002-09-03 Pharmacia & Upjohn Company Linezolid-crystal form II
US6716829B2 (en) * 2000-07-27 2004-04-06 Pharmacia Corporation Aldosterone antagonist and cyclooxygenase-2 inhibitor combination therapy to prevent or treat inflammation-related cardiovascular disorders
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
EP1490390A2 (de) * 2002-03-22 2004-12-29 Pharmacia Corporation C-17-spirolactonisierung und 6,7-oxidation von steroiden
TW200407150A (en) * 2002-11-06 2004-05-16 Upjohn Co Processes for preparing 7- carboxy substituted steroids
EP1562974B1 (de) * 2002-11-07 2007-02-21 Pharmacia & Upjohn Company LLC Verfahren zur herstellung c-7 substituierter 5-androstene

Also Published As

Publication number Publication date
US20030232981A1 (en) 2003-12-18
US20070106072A1 (en) 2007-05-10
WO2004037844A1 (en) 2004-05-06
US20070123704A1 (en) 2007-05-31
US20070117780A1 (en) 2007-05-24
EP1539795A1 (de) 2005-06-15
US20040127702A1 (en) 2004-07-01
US7411062B2 (en) 2008-08-12
US7414127B2 (en) 2008-08-19
DE60317214T2 (de) 2008-08-07
US20070100140A1 (en) 2007-05-03
US7235655B2 (en) 2007-06-26
ES2295663T3 (es) 2008-04-16
US7112670B2 (en) 2006-09-26
DE60317214D1 (de) 2007-12-13
US7417140B2 (en) 2008-08-26
AU2003282868A1 (en) 2004-05-13
JP2006505624A (ja) 2006-02-16
WO2004037844A8 (en) 2004-06-10
EP1539795B1 (de) 2007-10-31

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