NO20005889L - Benzimidazolderivater som ned-regulatorer av IgE - Google Patents

Benzimidazolderivater som ned-regulatorer av IgE

Info

Publication number
NO20005889L
NO20005889L NO20005889A NO20005889A NO20005889L NO 20005889 L NO20005889 L NO 20005889L NO 20005889 A NO20005889 A NO 20005889A NO 20005889 A NO20005889 A NO 20005889A NO 20005889 L NO20005889 L NO 20005889L
Authority
NO
Norway
Prior art keywords
ige
regulators
benzimidazole derivatives
allergens
allergy
Prior art date
Application number
NO20005889A
Other languages
English (en)
Norwegian (no)
Other versions
NO20005889D0 (no
Inventor
Jagadish Sircar
Mark L Richards
Michael G Campbell
Michael W Major
Original Assignee
Avanir Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22198947&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20005889(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals
Publication of NO20005889D0 publication Critical patent/NO20005889D0/no
Publication of NO20005889L publication Critical patent/NO20005889L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Amplifiers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
NO20005889A 1998-05-22 2000-11-21 Benzimidazolderivater som ned-regulatorer av IgE NO20005889L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8649498P 1998-05-22 1998-05-22
PCT/US1999/011490 WO1999061020A1 (en) 1998-05-22 1999-05-21 BENZIMIDAZOLE ANALOGS AS DOWN-REGULATORS OF IgE

Publications (2)

Publication Number Publication Date
NO20005889D0 NO20005889D0 (no) 2000-11-21
NO20005889L true NO20005889L (no) 2001-01-22

Family

ID=22198947

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20005889A NO20005889L (no) 1998-05-22 2000-11-21 Benzimidazolderivater som ned-regulatorer av IgE
NO20005887A NO20005887L (no) 1998-05-22 2000-11-21 Forbindelser med IgE-påvirkende egenskaper
NO20005888A NO20005888L (no) 1998-05-22 2000-11-21 Benzimidazolderivater som mudulatorer av IgE

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO20005887A NO20005887L (no) 1998-05-22 2000-11-21 Forbindelser med IgE-påvirkende egenskaper
NO20005888A NO20005888L (no) 1998-05-22 2000-11-21 Benzimidazolderivater som mudulatorer av IgE

Country Status (22)

Country Link
US (2) US6271390B1 (ru)
EP (3) EP1077700B1 (ru)
JP (3) JP2002516277A (ru)
KR (1) KR100591652B1 (ru)
CN (4) CN1721411A (ru)
AT (1) ATE292465T1 (ru)
AU (3) AU754943B2 (ru)
BR (3) BR9910640A (ru)
CA (3) CA2332989A1 (ru)
CZ (2) CZ20004350A3 (ru)
DE (1) DE69924607T2 (ru)
ES (1) ES2241285T3 (ru)
HU (3) HUP0101894A3 (ru)
IL (3) IL139828A0 (ru)
MX (3) MXPA00011467A (ru)
NO (3) NO20005889L (ru)
NZ (2) NZ508416A (ru)
PL (3) PL345219A1 (ru)
RU (2) RU2236220C2 (ru)
UA (2) UA67774C2 (ru)
WO (3) WO1999061013A2 (ru)
ZA (3) ZA200007754B (ru)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6911462B2 (en) * 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
BR9910640A (pt) * 1998-05-22 2001-10-30 Avanir Pharmaceuticals Compostos possuindo propriedades que afetam aige
US6919366B2 (en) * 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
RU2001106631A (ru) * 1998-09-11 2004-03-20 Адзиномото Ко., Инк. (Jp) Производные бензола и их фармацевтическое применение
US6270746B1 (en) * 1999-02-17 2001-08-07 David H. Katz Assay for the identification of IgE antibody suppressors
ATE467620T1 (de) * 1999-03-26 2010-05-15 Euro Celtique Sa Arylsubstituierte pyrazole, imidazole, oxazole, thiazole und pyrrole, sowie deren verwendung
BR0012046A (pt) * 1999-07-01 2002-05-14 Ajinomoto Kk Composto heterocìclico, composição farmacêutica, inibidor de ativação de ap-1 ou um inibidor da ativação de nf-kappab, inibidor da produção de citocina inflamatória, e, inibidor da produção de metaloprotease de matriz ou inibidor da expressão do fator de adesão de célula inflamatória
AU6866700A (en) 1999-09-01 2001-03-26 Ajinomoto Co., Inc. Biscyclopropanecarboxylic acid amide compounds and medicinal use thereof
US6759425B2 (en) 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
US6448281B1 (en) 2000-07-06 2002-09-10 Boehringer Ingelheim (Canada) Ltd. Viral polymerase inhibitors
US20070208087A1 (en) 2001-11-02 2007-09-06 Sanders Virginia J Compounds, compositions and methods for the treatment of inflammatory diseases
EP1368028B1 (en) * 2001-03-12 2007-08-15 Avanir Pharmaceuticals Benzimidazole compounds for modulating ige and inhibiting cellular proliferation
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
NZ530580A (en) * 2001-07-27 2007-02-23 Curis Inc Mediators of hedgehog signaling pathways, compositions and uses related thereto
ATE369854T1 (de) 2001-10-19 2007-09-15 Ortho Mcneil Pharm Inc 2-phenyl benzimidazole und imidazo-[4,5]-pyridine als cds1/chk2-inhibitoren und adjuvantien in der chemotherapie oder strahlungstherapie zur behandlung von krebs
US20080081788A1 (en) * 2002-01-14 2008-04-03 Lipps Binie V Diagnosis and treatment for immunoglobulin E (IgE) implicated disorders
US20030157555A1 (en) * 2002-01-14 2003-08-21 Lipps Binie V. Diagnosis and treatment for immunoglobulin E ( IgE) implicated disorders
TW200304820A (en) * 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
DK1511710T3 (en) 2002-05-31 2014-02-24 Proteotech Inc RELATIONSHIPS, PREPARATIONS AND METHODS FOR TREATING AMYLOID DISEASES AND SYNUCLEINOPATHES, SUCH AS ALZHEIMER'S DISEASE, TYPE 2-DIABETES AND PARKINSON'S DISEASE
EP1388535A1 (en) 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylated arylcycloalkylamines and their use as pharmaceuticals
DK1534335T4 (en) 2002-08-14 2015-10-05 Macrogenics Inc FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
WO2004024655A2 (en) 2002-09-12 2004-03-25 Avanir Pharmaceuticals Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
AU2003277689A1 (en) * 2002-11-02 2004-06-07 Kyung-Lim Lee Composition for preventing secretion of immunoglobulin e-dependent histamine releasing factor
GB2397301A (en) * 2003-01-14 2004-07-21 Novo Pharmaceuticals Ltd De Substituted 1,3,5-triazine derivatives
JP4726235B2 (ja) 2003-04-17 2011-07-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 癌の処置のためのチェックポイントキナーゼcds1(chk2)インヒビターとしての2−フェニル−ベンズイミダゾールおよび2−フェニル−イミダゾ−‘4,5!−ピリジン誘導体
EP1651198A2 (en) * 2003-08-08 2006-05-03 Avanir Pharmaceuticals Selective pharmacologic inhibition of protein trafficking and related methods of treating human diseases
EA200901463A1 (ru) 2004-02-20 2010-08-30 Бёрингер Ингельхайм Интернациональ Гмбх Ингибиторы вирусной полимеразы
CA2566090C (en) * 2004-05-12 2013-07-23 Alan D. Snow Substituted n-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies
ATE507206T1 (de) 2004-06-30 2011-05-15 Janssen Pharmaceutica Nv Arylsubstituiertes benzimidazol- und imidazopyridinether als wirkstoffe gegen krebs
WO2006040645A1 (en) * 2004-10-11 2006-04-20 Ranbaxy Laboratories Limited N-(3,5-dichloropyridin-4-yl)-2,4,5-alkoxy and 2,3,4-alkoxy benzamide derivatives as pde-iv (phophodiesterase type-iv) inhibitors for the treatment of inflammatory diseases such as asthma
CA2627722A1 (en) 2005-10-31 2007-06-21 Merck & Co., Inc. Cetp inhibitors
EP1790345A1 (en) * 2005-11-02 2007-05-30 Esbatech AG Triazin beta-secretase inhibitors
US7671221B2 (en) * 2005-12-28 2010-03-02 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
US7691902B2 (en) * 2005-12-28 2010-04-06 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
JP5764290B2 (ja) 2006-06-26 2015-08-19 マクロジェニクス,インコーポレーテッド FcγRIIB特異的抗体およびその使用法
WO2010045633A2 (en) * 2008-10-17 2010-04-22 National Jewish Health Measurement and analysis of leukotrienes
EP2367824B1 (en) 2008-12-23 2016-03-23 AbbVie Inc. Anti-viral derivatives of pyrimidine
CN102245604A (zh) 2008-12-23 2011-11-16 雅培制药有限公司 抗病毒化合物
CA2758484A1 (en) 2009-04-15 2010-10-21 David A. Degoey Anti-viral compounds
US8937150B2 (en) 2009-06-11 2015-01-20 Abbvie Inc. Anti-viral compounds
TWI402070B (zh) 2009-06-11 2013-07-21 Abbott Lab 抗病毒化合物
US8716454B2 (en) 2009-06-11 2014-05-06 Abbvie Inc. Solid compositions
US9394279B2 (en) 2009-06-11 2016-07-19 Abbvie Inc. Anti-viral compounds
WO2011068821A1 (en) * 2009-12-04 2011-06-09 Boehringer Ingelheim International Gmbh Benzimidazole inhibitors of leukotriene production
NZ605440A (en) 2010-06-10 2014-05-30 Abbvie Bahamas Ltd Solid compositions comprising an hcv inhibitor
KR20130091729A (ko) 2010-07-20 2013-08-19 베스타론 코포레이션 살충제 트라이아진 및 피리미딘
US8829200B2 (en) 2010-10-29 2014-09-09 Boehringer Ingelheim International Gmbh Benzimidazole inhibitors of leukotriene production
JP5789888B2 (ja) 2010-11-01 2015-10-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ロイコトリエン生成のベンゾイミダゾールインヒビター
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
US9034832B2 (en) 2011-12-29 2015-05-19 Abbvie Inc. Solid compositions
US11484534B2 (en) 2013-03-14 2022-11-01 Abbvie Inc. Methods for treating HCV
EP3089757A1 (en) 2014-01-03 2016-11-09 AbbVie Inc. Solid antiviral dosage forms
US11548867B2 (en) 2017-07-19 2023-01-10 Idea Ya Biosciences, Inc. Amido compounds as AhR modulators
US10889571B2 (en) * 2018-09-18 2021-01-12 Terns, Inc. Substituted benzoimidazoles and imidazo[4,5-c]pyridines for treating certain leukemias
CN110054558B (zh) * 2019-05-16 2022-03-25 海门瑞一医药科技有限公司 一种1-三氟甲基环丙烷-1-甲酸的制备方法
CN112441983B (zh) * 2019-08-29 2023-09-15 山东福长药业有限公司 一种基于苯并咪唑取代的硝基苯的化合物及其制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3017610A (en) * 1957-03-15 1962-01-16 Curtiss Wright Corp Electronic data file processor
US4939133A (en) * 1985-10-01 1990-07-03 Warner-Lambert Company N-substituted-2-hydroxy-α-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
US4744026A (en) * 1986-04-11 1988-05-10 American Telephone And Telegraph Company, At&T Bell Laboratories Methods and apparatus for efficient resource allocation
IT1232252B (it) 1989-02-22 1992-01-28 Rotta Research Lab Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione
DE59010069D1 (de) * 1989-11-21 1996-02-29 Bayer Ag Cumarinderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und Thiazolyl-essigsäurederivate als Zwischenprodukte
ATE128030T1 (de) * 1990-08-02 1995-10-15 Hoffmann La Roche Antiallergische mischung.
IE71647B1 (en) * 1991-01-28 1997-02-26 Rhone Poulenc Rorer Ltd Benzamide derivatives
FR2674856B1 (fr) * 1991-04-05 1993-07-30 Esteve Labor Dr Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments.
DE69309030T2 (de) * 1992-06-15 1997-09-25 Celltech Therapeutics Ltd Trisubstituierte phenylderivate als selektive phosphodiesterase iv inhibitoren
US5521813A (en) * 1993-01-15 1996-05-28 Strategic Weather Services System and method for the advanced prediction of weather impact on managerial planning applications
US5496826A (en) 1994-09-02 1996-03-05 Bristol-Myers Squibb Company Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides
JP3223090B2 (ja) * 1994-12-27 2001-10-29 三井化学株式会社 フェニルベンズイミダゾール誘導体
US5821258A (en) * 1994-12-27 1998-10-13 Mitsui Chemicals, Inc. Phenylbenzimidazole derivatives
RU2084451C1 (ru) * 1995-10-17 1997-07-20 Акционерное общество закрытого типа "Алмазный Центр" Способ получения 2-фенилбензимидазола
AU4988997A (en) * 1996-10-23 1998-05-15 Osteoscreen, Inc. Compositions and methods for treating bone deficit conditions
US6988076B2 (en) * 1997-05-21 2006-01-17 Khimetrics, Inc. Strategic planning and optimization system
BR9910640A (pt) * 1998-05-22 2001-10-30 Avanir Pharmaceuticals Compostos possuindo propriedades que afetam aige
US6910017B1 (en) * 1999-03-05 2005-06-21 Profitlogic, Inc. Inventory and price decision support
US6405175B1 (en) * 1999-07-27 2002-06-11 David Way Ng Shopping scouts web site for rewarding customer referrals on product and price information with rewards scaled by the number of shoppers using the information
US6546387B1 (en) * 1999-11-15 2003-04-08 Transcom Software Inc. Computer network information management system and method using intelligent software agents
US20020042739A1 (en) * 2000-03-13 2002-04-11 Kannan Srinivasan Method and system for creating and administering internet marketing promotions
US20020023001A1 (en) * 2000-07-11 2002-02-21 Mcfarlin James A. Method and apparatus for online creation and sale of custom local store marketing materials
US7072848B2 (en) * 2000-11-15 2006-07-04 Manugistics, Inc. Promotion pricing system and method
US20020198794A1 (en) * 2001-06-21 2002-12-26 Williams Edward P. Inventory management system for determining suggested part stocking levels for a vehicle dealer

Also Published As

Publication number Publication date
CN1219510C (zh) 2005-09-21
JP2002516274A (ja) 2002-06-04
JP2002516277A (ja) 2002-06-04
CN1317965A (zh) 2001-10-17
CZ20004350A3 (cs) 2002-02-13
EP1077700B1 (en) 2005-04-06
CA2332989A1 (en) 1999-12-02
NZ508416A (en) 2004-01-30
KR20010030179A (ko) 2001-04-16
HUP0102128A2 (hu) 2002-03-28
MXPA00011470A (es) 2002-10-17
KR100591652B1 (ko) 2006-06-26
AU4312099A (en) 1999-12-13
RU2236221C2 (ru) 2004-09-20
CA2332985A1 (en) 1999-12-02
AU754562B2 (en) 2002-11-21
IL139827A0 (en) 2002-02-10
PL345219A1 (en) 2001-12-03
WO1999061019A1 (en) 1999-12-02
US6451829B2 (en) 2002-09-17
ZA200007753B (en) 2001-07-18
HUP0101894A2 (hu) 2002-02-28
NO20005889D0 (no) 2000-11-21
HUP0102550A2 (hu) 2001-10-28
AU754943B2 (en) 2002-11-28
DE69924607D1 (de) 2005-05-12
ZA200007754B (en) 2001-08-16
CA2332999A1 (en) 1999-12-02
WO1999061020A1 (en) 1999-12-02
EP1077695A2 (en) 2001-02-28
UA67775C2 (ru) 2004-07-15
NO20005887D0 (no) 2000-11-21
UA67774C2 (ru) 2004-07-15
MXPA00011467A (es) 2002-10-17
PL345952A1 (en) 2002-01-14
WO1999061013A2 (en) 1999-12-02
NZ508413A (en) 2003-08-29
IL139826A0 (en) 2002-02-10
AU4094299A (en) 1999-12-13
US20020010343A1 (en) 2002-01-24
RU2236220C2 (ru) 2004-09-20
AU4197899A (en) 1999-12-13
EP1079830A1 (en) 2001-03-07
BR9910640A (pt) 2001-10-30
HUP0101894A3 (en) 2002-07-29
JP2002516276A (ja) 2002-06-04
HUP0102128A3 (en) 2002-05-28
NO20005887L (no) 2001-01-19
BR9910642A (pt) 2001-10-09
ATE292465T1 (de) 2005-04-15
DE69924607T2 (de) 2006-02-02
WO1999061013A3 (en) 2000-04-06
CN1721411A (zh) 2006-01-18
MXPA00011422A (es) 2002-12-13
US6271390B1 (en) 2001-08-07
ZA200007752B (en) 2001-12-05
ES2241285T3 (es) 2005-10-16
CN1311679A (zh) 2001-09-05
IL139828A0 (en) 2002-02-10
NO20005888L (no) 2001-01-22
HUP0102550A3 (en) 2002-11-28
CZ20004351A3 (cs) 2001-10-17
NO20005888D0 (no) 2000-11-21
CN1311675A (zh) 2001-09-05
PL345560A1 (en) 2001-12-17
EP1077700A1 (en) 2001-02-28
BR9910641A (pt) 2001-10-02

Similar Documents

Publication Publication Date Title
NO20005889L (no) Benzimidazolderivater som ned-regulatorer av IgE
MXJL03000027A (es) Compuestos de benzimidazol para modular la ige e inhibir la proliferacion celular.
DE69811363D1 (de) Piperazin-derivate und ihre verwendung als entzündungshemmende mittel
DE60327999D1 (de) Azolylaminoazine als inhibitoren von proteinkinasen
CY1108722T1 (el) Πολυκυκλικες ενωσεις και η χρηση τους ως αναστολεων των ενζυμων parp, vegfr2 και mlk3
MXJL05000010A (es) Compuestos de fenil-aza-benzimidazol para modular la ige e inhibir la proliferacion celular.
WO2004024896A3 (en) Phenyl-indole compounds
BRPI0409097A (pt) derivados de imidazol para tratamento de distúrbios alérgicos e hiperproliferativos
ATE205402T1 (de) Zusammensetzungen welche ein ace-hemmer und ein aldosereductasehemmer enthalten
DK0549666T3 (da) Nye aminobenzosultamderivater og deres anvendelse som lipoxygenaseinhibitorer
ATE401906T1 (de) Sedative stoffe und behandlungen
PT1207898E (pt) Tratamento da conjuntivite com proteinas histacalinicas
SE9901273D0 (sv) Novel compounds
NO20053247L (no) Anvendelse av levocetirizin ved behandling av vedvarende allergisk rhinitt.