NO20005295L - Effektiv rensing av adenovirus - Google Patents
Effektiv rensing av adenovirusInfo
- Publication number
- NO20005295L NO20005295L NO20005295A NO20005295A NO20005295L NO 20005295 L NO20005295 L NO 20005295L NO 20005295 A NO20005295 A NO 20005295A NO 20005295 A NO20005295 A NO 20005295A NO 20005295 L NO20005295 L NO 20005295L
- Authority
- NO
- Norway
- Prior art keywords
- adenovirus
- solution
- eluting
- applying
- sample solution
- Prior art date
Links
- 241000701161 unidentified adenovirus Species 0.000 title abstract 14
- 238000000034 method Methods 0.000 abstract 4
- 239000012539 chromatography resin Substances 0.000 abstract 3
- 239000012488 sample solution Substances 0.000 abstract 3
- 238000002835 absorbance Methods 0.000 abstract 2
- 238000005571 anion exchange chromatography Methods 0.000 abstract 2
- -1 dimethylaminopropyl Chemical group 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 239000011347 resin Substances 0.000 abstract 2
- 229920005989 resin Polymers 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- AIYUHDOJVYHVIT-UHFFFAOYSA-M caesium chloride Inorganic materials [Cl-].[Cs+] AIYUHDOJVYHVIT-UHFFFAOYSA-M 0.000 abstract 1
- 239000006166 lysate Substances 0.000 abstract 1
- 230000002934 lysing effect Effects 0.000 abstract 1
- 239000011259 mixed solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/20—Anion exchangers for chromatographic processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/06—Quantitative determination
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/621—Detectors specially adapted therefor signal-to-noise ratio
- G01N2030/625—Detectors specially adapted therefor signal-to-noise ratio by measuring reference material, e.g. carrier without sample
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/075—Adenoviridae
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Dry Shavers And Clippers (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8262898P | 1998-04-22 | 1998-04-22 | |
| PCT/US1999/008843 WO1999054441A1 (en) | 1998-04-22 | 1999-04-22 | Efficient purification of adenovirus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005295D0 NO20005295D0 (no) | 2000-10-20 |
| NO20005295L true NO20005295L (no) | 2000-11-30 |
Family
ID=22172352
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005295A NO20005295L (no) | 1998-04-22 | 2000-10-20 | Effektiv rensing av adenovirus |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US6383795B1 (de) |
| EP (1) | EP1073721B1 (de) |
| JP (1) | JP2002512361A (de) |
| AT (1) | ATE303434T1 (de) |
| AU (1) | AU756889B2 (de) |
| BG (1) | BG104928A (de) |
| BR (1) | BR9909789A (de) |
| CA (1) | CA2328462C (de) |
| DE (1) | DE69927013T2 (de) |
| EA (1) | EA200001096A1 (de) |
| EE (1) | EE200000605A (de) |
| HU (1) | HUP0102209A2 (de) |
| IL (1) | IL139040A0 (de) |
| IS (1) | IS5673A (de) |
| MX (1) | MXPA00010338A (de) |
| NO (1) | NO20005295L (de) |
| PL (1) | PL343630A1 (de) |
| SK (1) | SK15682000A3 (de) |
| WO (1) | WO1999054441A1 (de) |
| ZA (1) | ZA200005363B (de) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7732129B1 (en) * | 1998-12-01 | 2010-06-08 | Crucell Holland B.V. | Method for the production and purification of adenoviral vectors |
| ATE348155T1 (de) * | 1996-11-20 | 2007-01-15 | Introgen Therapeutics Inc | Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren |
| US6689600B1 (en) | 1998-11-16 | 2004-02-10 | Introgen Therapeutics, Inc. | Formulation of adenovirus for gene therapy |
| ATE332364T1 (de) | 1999-02-22 | 2006-07-15 | Transgene Sa | Verfahren zur gewinnung von purifizierter virenzuammensetzung |
| GB9915413D0 (en) * | 1999-07-01 | 1999-09-01 | Glaxo Group Ltd | Propagation method |
| US6447995B1 (en) | 2000-10-04 | 2002-09-10 | Genvec, Inc. | Utilizing intrinsic fluorescence to detect adenovirus |
| US7829084B2 (en) | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| JP3547715B2 (ja) * | 2001-03-06 | 2004-07-28 | 榮 新垣 | ベクター精製用装置及び方法 |
| JP2004538005A (ja) * | 2001-08-08 | 2004-12-24 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | シアル酸に結合するタンパク質を有するウイルスベクターの精製法 |
| EP1371723A1 (de) * | 2002-06-12 | 2003-12-17 | Procorde GmbH | Verfahren zur Herstellung von einer Adenoviruszubereitung |
| WO2004073624A2 (en) | 2003-02-14 | 2004-09-02 | The Curators Of The University Of Missouri | Contraceptive methods and compositions related to proteasomal interference |
| US20040166091A1 (en) * | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| GB0304576D0 (en) * | 2003-02-28 | 2003-04-02 | Lonza Biologics Plc | Protein a chromatography |
| WO2004112707A2 (en) * | 2003-06-18 | 2004-12-29 | Onyx Pharmaceuticals, Inc. | Method for purifying virus |
| ES2391975T3 (es) * | 2003-07-25 | 2012-12-03 | Genvec, Inc. | Vacunas a base de vector adenovírico |
| TWI228272B (en) * | 2003-09-19 | 2005-02-21 | Tinggi Technologies Pte Ltd | Fabrication of semiconductor devices |
| JP2007511507A (ja) * | 2003-11-14 | 2007-05-10 | ジェンベク、インコーポレイティッド | 癌を処置するための治療レジメン |
| EP1780269B1 (de) * | 2004-02-23 | 2009-07-08 | Crucell Holland B.V. | Verfahren zur Reinigung von Viren |
| EP2567967A3 (de) | 2004-04-12 | 2013-08-21 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Verwendung von adenoviralen Vektoren zur Erzeugung einer Immunantwort |
| GB0411081D0 (en) * | 2004-05-18 | 2004-06-23 | Glaxo Group Ltd | Novel apparatus |
| EP1784493A2 (de) * | 2004-09-01 | 2007-05-16 | The Government of the United States of America as Represented by The Department of Health and Human Services | Adenovirale vektoren mit der fähigkeit zum umwandeln von apcs, mögliche verwendung bei immunantworterzeugung |
| JP2008518632A (ja) | 2004-11-03 | 2008-06-05 | イントロゲン セラピューティックス， インコーポレイテッド | アデノウイルスベクターの製造および精製のための新規方法 |
| JP4626350B2 (ja) * | 2005-03-22 | 2011-02-09 | ソニー株式会社 | ハイブリダイゼーション検出に適する反応部などを有する流路系、該流路系を用いるハイブリダイゼーション検出装置 |
| IL296666A (en) | 2005-03-23 | 2022-11-01 | Genmab As | Antibodies against 38cd for the treatment of multiple myeloma |
| DK1869171T4 (en) * | 2005-04-11 | 2016-01-18 | Crucell Holland Bv | Virus cleaning using ultrafiltration |
| UA97469C2 (uk) | 2005-07-25 | 2012-02-27 | Емерджент Продакт Дівелопмент Сіетл, Елелсі | Гуманізована специфічна до cd37 зв'язувальна молекула імуноглобуліну |
| EP1951297A2 (de) * | 2005-11-10 | 2008-08-06 | GenVec, Inc. | Adenoviraler vektorbasierter impfstoff für die maul- und klauen-seuche |
| EP1808697A1 (de) * | 2006-01-13 | 2007-07-18 | Novartis Vaccines and Diagnostics, Inc. | Verwendung einer Ionenaustauschmatrix zur Bestimmung der Konzentration von Viruspartikeln und/oder Virusantigenen |
| MX363905B (es) * | 2006-06-12 | 2019-04-08 | Aptevo Res & Development Llc | Proteinas de union multivalentes monocatenarias con funcion efectora. |
| JP2010532764A (ja) * | 2007-07-06 | 2010-10-14 | トゥルビオン・ファーマシューティカルズ・インコーポレーテッド | Ｃ末端に配置された特異的結合性ドメインを有する結合性ペプチド |
| EP2222697B1 (de) | 2007-11-01 | 2012-12-05 | Perseid Therapeutics LLC | Immunosuppressive polypeptide und nukleinsäuren |
| NZ621443A (en) * | 2008-04-11 | 2015-09-25 | Emergent Product Dev Seattle | Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof |
| WO2010060719A1 (en) | 2008-11-03 | 2010-06-03 | Crucell Holland B.V. | Method for the production of adenoviral vectors |
| US9605844B2 (en) * | 2009-09-01 | 2017-03-28 | Cree, Inc. | Lighting device with heat dissipation elements |
| DK2536829T3 (en) | 2010-02-15 | 2016-07-04 | Crucell Holland Bv | A process for the production of Ad26-adenovirus vectors |
| WO2011119773A1 (en) | 2010-03-23 | 2011-09-29 | Roeth Jeremiah F | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
| CA2828411A1 (en) | 2011-03-04 | 2012-09-13 | Intrexon Corporation | Vectors conditionally expressing protein |
| CN102590431B (zh) * | 2012-02-10 | 2014-04-02 | 济南康众医药科技开发有限公司 | 一种治疗咳嗽的中药药物组合物检测方法 |
| BR112017001311A2 (pt) | 2014-09-07 | 2017-11-14 | Selecta Biosciences Inc | métodos e composições para atenuar as respostas imunes do vetor de transferência anti-viral de salto de éxon |
| TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
| CN108367004B (zh) | 2015-09-21 | 2022-09-13 | 阿帕特夫研究和发展有限公司 | Cd3结合多肽 |
| MX2019008143A (es) | 2017-01-07 | 2020-01-13 | Selecta Biosciences Inc | Dosificación sistemática de inmunosupresores acoplados a nanoportadores sintéticos. |
| JP7427584B2 (ja) | 2017-10-13 | 2024-02-05 | セレクタ バイオサイエンシーズ インコーポレーテッド | 抗ウイルス導入ベクターｉｇｍ応答を減弱化するための方法および組成物 |
| GB201806736D0 (en) * | 2018-04-25 | 2018-06-06 | Ge Healthcare Bioprocess R&D Ab | Method for virus purification |
| CN113710810A (zh) | 2019-02-21 | 2021-11-26 | 安利舒免疫溶瘤技术公司 | 溶瘤腺病毒载体和使用方法 |
| KR20220004121A (ko) | 2019-04-28 | 2022-01-11 | 셀렉타 바이오사이언시즈, 인크. | 바이러스 전달 벡터에 대한 기존의 면역을 갖는 대상체의 치료 방법 |
| KR20220015425A (ko) | 2019-05-28 | 2022-02-08 | 셀렉타 바이오사이언시즈, 인크. | 약화된 항바이러스 전달 벡터 면역 반응을 위한 방법 및 조성물 |
| CA3146831A1 (en) * | 2019-07-12 | 2021-01-21 | Sangamo Therapeutics, Inc. | Separation and quantification of empty and full viral capsid particles |
| EP4073102A4 (de) | 2019-12-12 | 2024-05-08 | Ting Therapeutics LLC | Zusammensetzungen und verfahren zur prävention und behandlung von gehörverlust |
| WO2023064367A1 (en) | 2021-10-12 | 2023-04-20 | Selecta Biosciences, Inc. | Methods and compositions for attenuating anti-viral transfer vector igm responses |
| WO2023172624A1 (en) | 2022-03-09 | 2023-09-14 | Selecta Biosciences, Inc. | Immunosuppressants in combination with anti-igm agents and related dosing |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788223A (en) * | 1985-07-26 | 1988-11-29 | Rohm And Haas Company | Low-rinse, high-capacity, weakly basic acrylic ion exchange resin |
| US5225989A (en) * | 1988-05-19 | 1993-07-06 | Fanuc Ltd. | Apparatus and method for performing simultaneous control of control axes of a machine tool |
| US5228989A (en) | 1989-07-06 | 1993-07-20 | Perseptive Biosystems, Inc. | Perfusive chromatography |
| US5019270A (en) | 1989-07-06 | 1991-05-28 | Perseptive Biosystems, Inc. | Perfusive chromatography |
| JPH06504482A (ja) * | 1991-01-04 | 1994-05-26 | パーセプティブ バイオシステムズ インコーポレイテッド | 親水性スルホンアミド結合コーティング |
| US5445732A (en) | 1992-06-19 | 1995-08-29 | Sepracor Inc. | Passivated porous polymer supports and methods for the preparation and use of same |
| US5268097A (en) | 1992-06-19 | 1993-12-07 | Sepracor Inc. | Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same |
| US5837520A (en) | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| JPH11511326A (ja) * | 1995-08-30 | 1999-10-05 | ジエンザイム コーポレイション | アデノウィルスおよびａａｖの精製 |
| CA2184132C (en) * | 1995-09-21 | 2011-03-15 | Kristina J. Hennessy | An adjuvanted vaccine which is substantially free of non-host albumin |
| CZ438398A3 (cs) * | 1996-07-01 | 1999-03-17 | Rhone-Poulenc Rorer S. A. | Způsob přípravy rekombinantních adenovirů |
| ATE348155T1 (de) * | 1996-11-20 | 2007-01-15 | Introgen Therapeutics Inc | Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren |
| AU779267B2 (en) | 1998-12-31 | 2005-01-13 | Centelion S.A.S. | Method for separating viral particles |
| ATE332364T1 (de) | 1999-02-22 | 2006-07-15 | Transgene Sa | Verfahren zur gewinnung von purifizierter virenzuammensetzung |
-
1999
- 1999-04-22 MX MXPA00010338A patent/MXPA00010338A/es unknown
- 1999-04-22 AT AT99918788T patent/ATE303434T1/de not_active IP Right Cessation
- 1999-04-22 HU HU0102209A patent/HUP0102209A2/hu unknown
- 1999-04-22 DE DE69927013T patent/DE69927013T2/de not_active Expired - Lifetime
- 1999-04-22 BR BR9909789-3A patent/BR9909789A/pt not_active Application Discontinuation
- 1999-04-22 WO PCT/US1999/008843 patent/WO1999054441A1/en not_active Ceased
- 1999-04-22 SK SK1568-2000A patent/SK15682000A3/sk unknown
- 1999-04-22 CA CA2328462A patent/CA2328462C/en not_active Expired - Lifetime
- 1999-04-22 EE EEP200000605A patent/EE200000605A/xx unknown
- 1999-04-22 EA EA200001096A patent/EA200001096A1/ru unknown
- 1999-04-22 PL PL99343630A patent/PL343630A1/xx unknown
- 1999-04-22 JP JP2000544773A patent/JP2002512361A/ja active Pending
- 1999-04-22 IL IL13904099A patent/IL139040A0/xx unknown
- 1999-04-22 US US09/296,962 patent/US6383795B1/en not_active Expired - Lifetime
- 1999-04-22 AU AU36620/99A patent/AU756889B2/en not_active Ceased
- 1999-04-22 EP EP99918788A patent/EP1073721B1/de not_active Expired - Lifetime
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2000
- 2000-10-03 ZA ZA200005363A patent/ZA200005363B/xx unknown
- 2000-10-20 IS IS5673A patent/IS5673A/is unknown
- 2000-10-20 NO NO20005295A patent/NO20005295L/no not_active Application Discontinuation
- 2000-11-08 BG BG104928A patent/BG104928A/xx unknown
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2001
- 2001-11-30 US US09/997,909 patent/US6586226B2/en not_active Expired - Lifetime
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- 2003-05-05 US US10/429,303 patent/US7141406B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7141406B2 (en) | 2006-11-28 |
| DE69927013D1 (de) | 2005-10-06 |
| WO1999054441A8 (en) | 2000-02-24 |
| ZA200005363B (en) | 2001-09-25 |
| US6586226B2 (en) | 2003-07-01 |
| EP1073721B1 (de) | 2005-08-31 |
| CA2328462C (en) | 2010-11-09 |
| SK15682000A3 (sk) | 2001-05-10 |
| MXPA00010338A (es) | 2005-06-17 |
| ATE303434T1 (de) | 2005-09-15 |
| HUP0102209A2 (hu) | 2001-09-28 |
| AU756889B2 (en) | 2003-01-23 |
| BR9909789A (pt) | 2000-12-26 |
| CA2328462A1 (en) | 1999-10-28 |
| IS5673A (is) | 2000-10-20 |
| NO20005295D0 (no) | 2000-10-20 |
| DE69927013T2 (de) | 2006-06-29 |
| EP1073721A1 (de) | 2001-02-07 |
| BG104928A (bg) | 2001-09-28 |
| US6383795B1 (en) | 2002-05-07 |
| AU3662099A (en) | 1999-11-08 |
| PL343630A1 (en) | 2001-08-27 |
| US20020034735A1 (en) | 2002-03-21 |
| JP2002512361A (ja) | 2002-04-23 |
| EE200000605A (et) | 2002-04-15 |
| EA200001096A1 (ru) | 2001-04-23 |
| US20030203469A1 (en) | 2003-10-30 |
| WO1999054441A1 (en) | 1999-10-28 |
| IL139040A0 (en) | 2001-11-25 |
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