ATE332364T1 - Verfahren zur gewinnung von purifizierter virenzuammensetzung - Google Patents
Verfahren zur gewinnung von purifizierter virenzuammensetzungInfo
- Publication number
- ATE332364T1 ATE332364T1 AT00906444T AT00906444T ATE332364T1 AT E332364 T1 ATE332364 T1 AT E332364T1 AT 00906444 T AT00906444 T AT 00906444T AT 00906444 T AT00906444 T AT 00906444T AT E332364 T1 ATE332364 T1 AT E332364T1
- Authority
- AT
- Austria
- Prior art keywords
- purified virus
- virus composition
- obtaining purified
- viral
- particles
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title 1
- 230000003612 virological effect Effects 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9902167 | 1999-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332364T1 true ATE332364T1 (de) | 2006-07-15 |
Family
ID=9542357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00906444T ATE332364T1 (de) | 1999-02-22 | 2000-02-21 | Verfahren zur gewinnung von purifizierter virenzuammensetzung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7264958B1 (de) |
| EP (1) | EP1155120B1 (de) |
| JP (2) | JP4802366B2 (de) |
| AT (1) | ATE332364T1 (de) |
| AU (1) | AU774437B2 (de) |
| CA (1) | CA2364934C (de) |
| DE (1) | DE60029195T2 (de) |
| WO (1) | WO2000050573A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EE200000605A (et) | 1998-04-22 | 2002-04-15 | Genvec, Inc. | Adenoviiruse efektiivne puhastamine |
| EP1407006B9 (de) * | 2001-12-20 | 2006-10-18 | Bavarian Nordic A/S | Methode zur gewinnung und reinigung von poxviren aus infizierten zellen |
| ATE500267T1 (de) | 2003-07-21 | 2011-03-15 | Transgene Sa | Multifunktionelle cytokine |
| CN1922308A (zh) | 2004-02-23 | 2007-02-28 | 克鲁塞尔荷兰公司 | 病毒纯化方法 |
| CA2602944C (en) | 2005-04-11 | 2015-08-11 | Crucell Holland B.V. | Virus purification using ultrafiltration |
| JP4670583B2 (ja) * | 2005-10-20 | 2011-04-13 | チッソ株式会社 | 水溶性カチオン性磁気微粒子を用いた脂質ベシクルの分離又は検出方法 |
| SG188908A1 (en) | 2006-07-14 | 2013-04-30 | Wisconsin Alumni Res Found | Adsorptive membranes for trapping viruses |
| US8420103B2 (en) | 2007-01-30 | 2013-04-16 | Transgene S.A. | Papillomavirus vaccines |
| WO2010060719A1 (en) | 2008-11-03 | 2010-06-03 | Crucell Holland B.V. | Method for the production of adenoviral vectors |
| DK2382474T3 (en) | 2009-01-20 | 2015-04-07 | Transgene Sa | SOLUBLE ICAM-1 as a biomarker FOR PREDICTION OF THERAPEUTIC RESPONSE |
| MX2011010061A (es) | 2009-03-24 | 2011-11-18 | Transgene Sa | Biomarcador para monitorear pacientes. |
| EP2419728B1 (de) | 2009-04-17 | 2014-01-08 | Transgene SA | Biomarker für patientenüberwachung |
| AU2010270313B2 (en) | 2009-07-10 | 2014-05-22 | Transgene Sa | Biomarker for selecting patients and related methods |
| KR20120052352A (ko) | 2009-08-07 | 2012-05-23 | 트랜스진 에스.에이. | Hbv 감염을 치료하는 조성물 |
| EP2536829B1 (de) | 2010-02-15 | 2016-04-06 | Crucell Holland B.V. | Verfahren zur Herstellung von adenoviralen Ad26-Vektoren |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| SG190031A1 (en) * | 2010-10-27 | 2013-06-28 | Philip Morris Prod | Methods for capturing virus like particles from plants using expanded bed chromatography |
| BR112013014457A8 (pt) | 2010-12-09 | 2017-12-19 | Pasteur Institut | usos da enzima 6-metilguanina-dna-metiltrasferase (mgmt, ec 2.1.1.63) para aumentar a produção de proteína heteróloga, bem como vetor de expressão, células recombinantes e polipeptídeo de fusão compreendendo sinal de secreção peptídica e proteína snap |
| ES2655051T3 (es) | 2011-08-26 | 2018-02-16 | Wisconsin Alumni Research Foundation | Virus de la gripe con segmento génico PB2 mutante como vacunas vivas atenuadas |
| TW201321016A (zh) | 2011-09-29 | 2013-06-01 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二) |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
| WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
| CA2878800A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterial antigen vaccine |
| WO2014066443A1 (en) | 2012-10-23 | 2014-05-01 | Emory University | Gm-csf and il-4 conjugates, compositions, and methods related thereto |
| JP6797680B2 (ja) | 2013-06-14 | 2020-12-16 | サイオクサス セラピューティクス リミテッド | B型アデノウイルスのための投与計画および製剤 |
| SI3021859T1 (en) | 2013-10-25 | 2018-04-30 | Psioxus Therapeutics Limited | Oncolytic adenoviruses equipped with heterologous genes |
| RU2695462C2 (ru) | 2014-01-09 | 2019-07-23 | Трансген Са | Гибридизация гетероолигомерных микобактериальных антигенов |
| US10053671B2 (en) | 2014-06-20 | 2018-08-21 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| EP3256156B1 (de) | 2015-02-13 | 2025-02-12 | Transgene | Immunotherapeutischer impfstoff und antikörperkombinationstherapie |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| CN108697745A (zh) | 2015-12-17 | 2018-10-23 | 皮斯奥克斯治疗公司 | 编码抗tcr复合体抗体或片段的b组腺病毒 |
| AU2017221444B2 (en) | 2016-02-19 | 2021-07-29 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza B virus replication for vaccine development |
| CA3023022A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| GB201713765D0 (en) | 2017-08-28 | 2017-10-11 | Psioxus Therapeutics Ltd | Modified adenovirus |
| IL303187A (en) | 2016-08-29 | 2023-07-01 | Akamis Bio Ltd | Adenovirus with bispecific T cell activator |
| EP3522920A2 (de) | 2016-10-10 | 2019-08-14 | Transgene SA | Immuntherapeutisches produkt und mdsc-modulator-kombinationstherapie |
| JP7078620B2 (ja) | 2016-11-16 | 2022-05-31 | イミュノミック セラピューティックス, インコーポレイテッド | アレルギーの治療のための核酸 |
| EP4512477A3 (de) | 2017-04-22 | 2025-06-11 | Immunomic Therapeutics, Inc. | Verbesserte lampenkonstruktionen |
| CN110913892A (zh) | 2017-05-02 | 2020-03-24 | 免疫治疗有限公司 | 包含癌抗原的lamp(溶酶体相关膜蛋白)构建物 |
| US11197926B2 (en) | 2017-10-25 | 2021-12-14 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| GB201801614D0 (en) | 2018-01-31 | 2018-03-14 | Psioxus Therapeutics Ltd | Formulation |
| CA3100004A1 (en) | 2018-05-15 | 2019-11-21 | Immunomic Therapeutics, Inc. | Improved lamp constructs comprising allergens |
| US12343390B2 (en) | 2018-08-07 | 2025-07-01 | Wisconsin Alumni Research Foundation (Warf) | Recombinant biologically contained filovirus vaccine |
| US11389523B2 (en) | 2018-08-20 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (HA) protein |
| CA3113648A1 (en) | 2018-09-21 | 2020-03-26 | University Of Connecticut | Compositions and methods to restore paternal ube3a gene expression in human angelman syndrome |
| CN113543875A (zh) * | 2018-11-22 | 2021-10-22 | 固定噬菌体有限公司 | 产生固定噬菌体 |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| CN113874496A (zh) | 2019-02-08 | 2021-12-31 | 威斯康星校友研究基金会(Warf) | 人源化细胞系 |
| WO2020223699A1 (en) | 2019-05-01 | 2020-11-05 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
| GB201909081D0 (en) * | 2019-06-25 | 2019-08-07 | Psioxus Therapeutics Ltd | Method |
| JP7627911B2 (ja) | 2019-08-27 | 2025-02-07 | ウィスコンシン アルムニ リサーチ ファンデイション | 卵内複製のための安定化されたhaを持つ組換えインフルエンザウイルス |
| WO2021077051A1 (en) | 2019-10-18 | 2021-04-22 | Immunomic Therapeutics, Inc | Improved lamp constructs comprising cancer antigens |
| AU2020385683A1 (en) | 2019-11-18 | 2022-06-30 | Janssen Biotech, Inc. | Vaccines based on mutant CALR and JAK2 and their uses |
| WO2021150874A1 (en) | 2020-01-24 | 2021-07-29 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized na |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| WO2021195410A1 (en) | 2020-03-25 | 2021-09-30 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| JP2023521194A (ja) | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク,インコーポレーテツド | Psma及びsteap1ワクチン並びにそれらの使用 |
| US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
| WO2022009051A1 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | A method for determining responsiveness to prostate cancer treatment |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| US20230241530A1 (en) * | 2022-02-01 | 2023-08-03 | W. L. Gore & Associates, Inc. | Affinity chromatography devices containing a heat treated fibrillated polymer membrane for the separation of mrna and viral vectors from an aqueous mixture |
| EP4508071A1 (de) | 2022-04-10 | 2025-02-19 | Immunomic Therapeutics, Inc. | Bicistronische lampenkonstrukte mit immunreaktionserhöhenden genen und verfahren zur verwendung davon |
| WO2025158316A1 (en) | 2024-01-26 | 2025-07-31 | Janssen Biotech, Inc. | Ovarian neoantigens and use thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0328256A1 (de) * | 1988-01-21 | 1989-08-16 | Owens-Corning Fiberglas Corporation | Glasfaser, überzogen mit Agarose, zur Verwendung als Säulenpackung oder chromatographisches Medium in Biotrennungen |
| GB8806605D0 (en) * | 1988-03-19 | 1988-04-20 | Robinson E | Composite adsorbents |
| SE9101149D0 (sv) | 1991-04-17 | 1991-04-17 | Pharmacia Lkb Biotech | Beads for down stream processing |
| DE4128953A1 (de) * | 1991-08-30 | 1993-03-04 | Basf Ag | Verfahren zur kultivierung von saeugerzellen im fliessbettreaktor |
| US5837520A (en) * | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| AU722196B2 (en) * | 1995-08-30 | 2000-07-27 | Genzyme Corporation | Chromatographic purification of adenovirus and AAV |
| US6027888A (en) * | 1996-04-05 | 2000-02-22 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells |
| CZ438398A3 (cs) | 1996-07-01 | 1999-03-17 | Rhone-Poulenc Rorer S. A. | Způsob přípravy rekombinantních adenovirů |
| JP4492826B2 (ja) | 1996-11-20 | 2010-06-30 | イントロジェン セラピューティクス,インコーポレイテッド | アデノウイルスベクターの産生および精製のための改良された方法 |
| DE69739961D1 (de) | 1996-12-13 | 2010-09-23 | Schering Corp | Methoden zur Virus-Reinigung |
| SE9700383D0 (sv) * | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| JP2001519930A (ja) | 1998-02-04 | 2001-10-23 | サンマイクロシステムズ インコーポレーテッド | 階層型ハッシュを用いた効率的な認証及び完全性検査の方法及びその装置 |
| EE200000605A (et) | 1998-04-22 | 2002-04-15 | Genvec, Inc. | Adenoviiruse efektiivne puhastamine |
-
2000
- 2000-02-21 DE DE60029195T patent/DE60029195T2/de not_active Expired - Lifetime
- 2000-02-21 US US09/914,036 patent/US7264958B1/en not_active Expired - Lifetime
- 2000-02-21 EP EP00906444A patent/EP1155120B1/de not_active Expired - Lifetime
- 2000-02-21 JP JP2000601137A patent/JP4802366B2/ja not_active Expired - Lifetime
- 2000-02-21 AU AU28118/00A patent/AU774437B2/en not_active Expired
- 2000-02-21 CA CA2364934A patent/CA2364934C/fr not_active Expired - Lifetime
- 2000-02-21 AT AT00906444T patent/ATE332364T1/de active
- 2000-02-21 WO PCT/FR2000/000430 patent/WO2000050573A1/fr not_active Ceased
-
2011
- 2011-01-20 JP JP2011009922A patent/JP2011120596A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1155120A1 (de) | 2001-11-21 |
| CA2364934C (fr) | 2011-10-18 |
| JP2002536992A (ja) | 2002-11-05 |
| EP1155120B1 (de) | 2006-07-05 |
| US7264958B1 (en) | 2007-09-04 |
| AU2811800A (en) | 2000-09-14 |
| AU774437B2 (en) | 2004-06-24 |
| JP2011120596A (ja) | 2011-06-23 |
| JP4802366B2 (ja) | 2011-10-26 |
| DE60029195D1 (de) | 2006-08-17 |
| DE60029195T2 (de) | 2007-06-28 |
| WO2000050573A1 (fr) | 2000-08-31 |
| CA2364934A1 (fr) | 2000-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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