ATE332364T1 - Verfahren zur gewinnung von purifizierter virenzuammensetzung - Google Patents
Verfahren zur gewinnung von purifizierter virenzuammensetzungInfo
- Publication number
- ATE332364T1 ATE332364T1 AT00906444T AT00906444T ATE332364T1 AT E332364 T1 ATE332364 T1 AT E332364T1 AT 00906444 T AT00906444 T AT 00906444T AT 00906444 T AT00906444 T AT 00906444T AT E332364 T1 ATE332364 T1 AT E332364T1
- Authority
- AT
- Austria
- Prior art keywords
- purified virus
- virus composition
- obtaining purified
- viral
- particles
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title 1
- 230000003612 virological effect Effects 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9902167 | 1999-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332364T1 true ATE332364T1 (de) | 2006-07-15 |
Family
ID=9542357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00906444T ATE332364T1 (de) | 1999-02-22 | 2000-02-21 | Verfahren zur gewinnung von purifizierter virenzuammensetzung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7264958B1 (de) |
| EP (1) | EP1155120B1 (de) |
| JP (2) | JP4802366B2 (de) |
| AT (1) | ATE332364T1 (de) |
| AU (1) | AU774437B2 (de) |
| CA (1) | CA2364934C (de) |
| DE (1) | DE60029195T2 (de) |
| WO (1) | WO2000050573A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL343630A1 (en) | 1998-04-22 | 2001-08-27 | Genvec Inc | Efficient purification of adenovirus |
| ATE302268T1 (de) * | 2001-12-20 | 2005-09-15 | Bavarian Nordic As | Methode zur gewinnung und reinigung von poxviren aus infizierten zellen |
| CA2678736A1 (en) | 2003-07-21 | 2005-02-17 | Transgene S.A. | Novel multifunctional il-2 - il-18 fusion proteins |
| JP2007522814A (ja) | 2004-02-23 | 2007-08-16 | クルセル ホランド ベー ヴェー | ウイルスの精製方法 |
| ATE412737T1 (de) | 2005-04-11 | 2008-11-15 | Crucell Holland Bv | Virusreinigung mit ultrafiltration |
| JP4670583B2 (ja) * | 2005-10-20 | 2011-04-13 | チッソ株式会社 | 水溶性カチオン性磁気微粒子を用いた脂質ベシクルの分離又は検出方法 |
| US9375499B2 (en) | 2006-07-14 | 2016-06-28 | Wisconsin Alumni Research Foundation | Adsorptive membranes for trapping viruses |
| EP2390340A3 (de) | 2007-01-30 | 2012-02-22 | Transgene SA | Papillomavirus E1 und E2-Polypeptiden mit reduziertem Identitätsanteil kodierender Vektor |
| KR101504392B1 (ko) | 2008-11-03 | 2015-03-19 | 크루셀 홀란드 비.브이. | 아데노바이러스 벡터의 제조방법 |
| WO2010084100A1 (en) | 2009-01-20 | 2010-07-29 | Transgene Sa | Soluble icam-1 as biomarker for prediction of therapeutic response |
| ES2555858T3 (es) | 2009-03-24 | 2016-01-11 | Transgene Sa | Biomarcador para el control de pacientes |
| HRP20140262T1 (hr) | 2009-04-17 | 2014-04-25 | Transgene Sa | Biomarker za praä†enje pacijenata |
| DK2452194T3 (en) | 2009-07-10 | 2015-11-30 | Transgene Sa | Biomarker PATIENT SELECTION AND RELATED PRACTICES |
| BR112012002628B1 (pt) | 2009-08-07 | 2021-09-08 | Transgene Sa | Composição imunogênica, molécula de ácido nucleico, vetor, partícula viral infecciosa, micro-organismo transgênico, composição, usos da composição imunogênica e kit de partes |
| NZ601424A (en) | 2010-02-15 | 2014-07-25 | Crucell Holland Bv | Method for the production of ad26 adenoviral vectors |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| KR20130122947A (ko) * | 2010-10-27 | 2013-11-11 | 필립모리스 프로덕츠 에스.에이. | 팽창성 베드 크로마토그래피를 사용하여 식물로부터 바이러스 유사 입자를 포획하는 방법 |
| WO2012076715A1 (en) | 2010-12-09 | 2012-06-14 | Institut Pasteur | Mgmt-based method for obtaining high yield of recombinant protein expression |
| JP2014527799A (ja) | 2011-08-26 | 2014-10-23 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | 変異型pb2遺伝子セグメントを有する弱毒化生ワクチンとしてのインフルエンザウイルス |
| TW201321016A (zh) | 2011-09-29 | 2013-06-01 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二) |
| WO2013045658A1 (en) | 2011-09-29 | 2013-04-04 | Transgene Sa | Immunotherapy composition and regimen for treating hepatitis c virus infection |
| WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
| CA2878800A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterial antigen vaccine |
| EP3587455A1 (de) | 2012-10-23 | 2020-01-01 | Emory University | Gm-csf- und il-4-konjugate, zusammensetzungen und zugehörige verfahren |
| KR20210054067A (ko) | 2013-06-14 | 2021-05-12 | 싸이오서스 테라퓨틱스 엘티디. | 유형 b 아데노바이러스에 대한 투여 요법 및 제형 |
| EP3831398A1 (de) | 2013-10-25 | 2021-06-09 | PsiOxus Therapeutics Limited | Onkolytische adenoviren, die mit heterologen genen ausgestattet sind |
| RU2695462C2 (ru) | 2014-01-09 | 2019-07-23 | Трансген Са | Гибридизация гетероолигомерных микобактериальных антигенов |
| WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| CN107949397A (zh) | 2015-02-13 | 2018-04-20 | 特兰斯吉恩股份有限公司 | 免疫治疗疫苗和抗体组合治疗 |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| MY193281A (en) | 2015-12-17 | 2022-09-30 | Psioxus Therapeutics Ltd | Group b adenovirus encoding an anti-tcr-complex antibody or fragment |
| JP2019510481A (ja) | 2016-02-19 | 2019-04-18 | ウィスコンシン アルムニ リサーチ ファンデイション | ワクチン開発のための改善されたb型インフルエンザウイルス複製 |
| WO2017191147A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| JP2019532621A (ja) | 2016-08-29 | 2019-11-14 | サイオクサス セラピューティクス リミテッド | 二重特異性T細胞エンゲージャー(BiTE)で武装したアデノウイルス |
| GB201713765D0 (en) | 2017-08-28 | 2017-10-11 | Psioxus Therapeutics Ltd | Modified adenovirus |
| US20190328869A1 (en) | 2016-10-10 | 2019-10-31 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
| JP7078620B2 (ja) | 2016-11-16 | 2022-05-31 | イミュノミック セラピューティックス, インコーポレイテッド | アレルギーの治療のための核酸 |
| ES3004084T3 (en) | 2017-04-22 | 2025-03-11 | Immunomic Therapeutics Inc | Improved lamp constructs |
| KR20200016224A (ko) | 2017-05-02 | 2020-02-14 | 이뮤노믹 쎄라퓨틱스, 인크. | 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물 |
| EP3700562A1 (de) | 2017-10-25 | 2020-09-02 | Wisconsin Alumni Research Foundation (WARF) | Rekombinante influenzaviren mit stabilisiertem ha zur replikation in eiern |
| GB201801614D0 (en) | 2018-01-31 | 2018-03-14 | Psioxus Therapeutics Ltd | Formulation |
| US12398195B2 (en) | 2018-05-15 | 2025-08-26 | Immunomic Therapeutics, Inc. | Lamp constructs comprising allergens |
| JP7783047B2 (ja) * | 2018-08-07 | 2025-12-09 | ウィスコンシン アルムニ リサーチ ファンデイション | 組換えの生物学的に封じ込められたフィロウイルスワクチン |
| EP3840780A1 (de) | 2018-08-20 | 2021-06-30 | Wisconsin Alumni Research Foundation | Vektoren zur auslösung von immunantworten auf nicht-dominante epitope im hämagglutinin (ha)-protein |
| AU2019344006B2 (en) | 2018-09-21 | 2025-11-27 | University Of Connecticut | Compositions and methods to restore paternal UBE3A gene expression in human Angelman Syndrome |
| EP3883682A1 (de) * | 2018-11-22 | 2021-09-29 | Fixed Phage Limited | Herstellung immobilisierter bakteriophagen |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| US11851648B2 (en) | 2019-02-08 | 2023-12-26 | Wisconsin Alumni Research Foundation (Warf) | Humanized cell line |
| WO2020223699A1 (en) | 2019-05-01 | 2020-11-05 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
| GB201909081D0 (en) * | 2019-06-25 | 2019-08-07 | Psioxus Therapeutics Ltd | Method |
| WO2021041624A2 (en) | 2019-08-27 | 2021-03-04 | Yoshihiro Kawaoka | Recombinant influenza viruses with stabilized ha for replication in eggs |
| CN114641306A (zh) | 2019-10-18 | 2022-06-17 | 免疫治疗有限公司 | 包含癌抗原的改良lamp构建物 |
| IL293051A (en) | 2019-11-18 | 2022-07-01 | Janssen Biotech Inc | Vaccines based on mutant calr and jak2 and their uses |
| JP2023511444A (ja) | 2020-01-24 | 2023-03-17 | ウィスコンシン アルムニ リサーチ ファンデイション | 安定化されたnaを有する組換えインフルエンザウイルス |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| US12290562B2 (en) | 2020-03-25 | 2025-05-06 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| JP2023521194A (ja) | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク,インコーポレーテツド | Psma及びsteap1ワクチン並びにそれらの使用 |
| EP4175721A1 (de) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostata-neoantigene und ihre verwendungen |
| WO2022009051A1 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | A method for determining responsiveness to prostate cancer treatment |
| US12295997B2 (en) | 2020-07-06 | 2025-05-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| US20230241530A1 (en) * | 2022-02-01 | 2023-08-03 | W. L. Gore & Associates, Inc. | Affinity chromatography devices containing a heat treated fibrillated polymer membrane for the separation of mrna and viral vectors from an aqueous mixture |
| EP4508071A1 (de) | 2022-04-10 | 2025-02-19 | Immunomic Therapeutics, Inc. | Bicistronische lampenkonstrukte mit immunreaktionserhöhenden genen und verfahren zur verwendung davon |
| WO2025158316A1 (en) | 2024-01-26 | 2025-07-31 | Janssen Biotech, Inc. | Ovarian neoantigens and use thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0328256A1 (de) * | 1988-01-21 | 1989-08-16 | Owens-Corning Fiberglas Corporation | Glasfaser, überzogen mit Agarose, zur Verwendung als Säulenpackung oder chromatographisches Medium in Biotrennungen |
| GB8806605D0 (en) | 1988-03-19 | 1988-04-20 | Robinson E | Composite adsorbents |
| SE9101149D0 (sv) | 1991-04-17 | 1991-04-17 | Pharmacia Lkb Biotech | Beads for down stream processing |
| DE4128953A1 (de) * | 1991-08-30 | 1993-03-04 | Basf Ag | Verfahren zur kultivierung von saeugerzellen im fliessbettreaktor |
| US5837520A (en) * | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| CA2625279A1 (en) * | 1995-08-30 | 1997-03-06 | Genzyme Corporation | Chromatographic purification of adenovirus and aav |
| US6027888A (en) * | 1996-04-05 | 2000-02-22 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells |
| US6485958B2 (en) | 1996-07-01 | 2002-11-26 | Gencell Sa | Method for producing recombinant adenovirus |
| WO1998022588A2 (en) | 1996-11-20 | 1998-05-28 | Introgen Therapeutics, Inc. | An improved method for the production and purification of adenoviral vectors |
| EP0948601B1 (de) | 1996-12-13 | 2007-02-14 | Schering Corporation | Methoden zur virus-reinigung |
| SE9700383D0 (sv) * | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| EP0972374A1 (de) | 1998-02-04 | 2000-01-19 | Sun Microsystems, Inc. | Verfahren und vorrichtung zur effizienten authentifizierung und prüfung der integrität unter verwendung von hierarchischem hashing |
| PL343630A1 (en) | 1998-04-22 | 2001-08-27 | Genvec Inc | Efficient purification of adenovirus |
-
2000
- 2000-02-21 CA CA2364934A patent/CA2364934C/fr not_active Expired - Lifetime
- 2000-02-21 AU AU28118/00A patent/AU774437B2/en not_active Expired
- 2000-02-21 WO PCT/FR2000/000430 patent/WO2000050573A1/fr not_active Ceased
- 2000-02-21 AT AT00906444T patent/ATE332364T1/de active
- 2000-02-21 DE DE60029195T patent/DE60029195T2/de not_active Expired - Lifetime
- 2000-02-21 US US09/914,036 patent/US7264958B1/en not_active Expired - Lifetime
- 2000-02-21 EP EP00906444A patent/EP1155120B1/de not_active Expired - Lifetime
- 2000-02-21 JP JP2000601137A patent/JP4802366B2/ja not_active Expired - Lifetime
-
2011
- 2011-01-20 JP JP2011009922A patent/JP2011120596A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP4802366B2 (ja) | 2011-10-26 |
| US7264958B1 (en) | 2007-09-04 |
| DE60029195D1 (de) | 2006-08-17 |
| WO2000050573A1 (fr) | 2000-08-31 |
| EP1155120B1 (de) | 2006-07-05 |
| CA2364934A1 (fr) | 2000-08-31 |
| DE60029195T2 (de) | 2007-06-28 |
| EP1155120A1 (de) | 2001-11-21 |
| AU2811800A (en) | 2000-09-14 |
| CA2364934C (fr) | 2011-10-18 |
| AU774437B2 (en) | 2004-06-24 |
| JP2002536992A (ja) | 2002-11-05 |
| JP2011120596A (ja) | 2011-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60029195D1 (de) | Verfahren zur gewinnung von purifizierter virenzuammensetzung | |
| ATE324436T1 (de) | Verfahren zur reinigung von menschlichen, dem papillomavirus ähnlichen partikeln. | |
| ATE306252T1 (de) | Verfahren zur herstellung kristalliner partikel zur inhalation | |
| ATE278785T1 (de) | Neues verfahren zur gewinnung und reinigung von fusionsproteinen | |
| ATE322252T1 (de) | Verfahren zur herstellung und sammlung von kristallinen partikeln | |
| DE60114348D1 (de) | Verfahren zur Reinigung von Gasen | |
| DE69637509D1 (de) | Verfahren zur reinigung von faktor-ix | |
| DE69908998D1 (de) | Verfahren zur Herstellung von Kohlenstoff | |
| DE69703957D1 (de) | Verfahren zur Herstellung von kristallinen Ceroxidteilchen. | |
| AU1811301A (en) | Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon | |
| DE59800264D1 (de) | Verfahren zur Herstellung von SiO2-Granulat | |
| DE60132094D1 (de) | Verfahren zur Herstellung von gereinigten Partikeln | |
| DE60120819D1 (de) | Verfahren zur adsorptiven Trennung von Kohlendioxid | |
| DE60330146D1 (de) | Verfahren zur reinigung von fibrinogen | |
| DE60203975D1 (de) | Verfahren zur Herstellung von magnetischen Teilchen, magnetische Teilchen und magnetischer Werkstoff | |
| DE69531308D1 (de) | Verfahren zur Herstellung von gereinigten papillomavirus Proteinen | |
| DE60011396D1 (de) | Verfahren zur herstellung von iopamidol | |
| AU2003279240A1 (en) | Methods for purifying viral particles for gene therapy | |
| ATE509889T1 (de) | Verfahren zur herstellung von granulatförmigem umhüllten natriumpercarbonat und verfahrensgemäss erhältliches produkt | |
| DE69931976D1 (de) | Verfahren zur Herstellung von Aminophosphinen und Aminophosphinoxiden, Zwischenprodukte dafür | |
| DE60032077D1 (de) | Verfahren zur dehalogenierung von kohlenwasserstoffhaltigen kohlenstoff-kohlenstoff doppelbindungen | |
| DE60129907D1 (de) | Verfahren zur Reinigung von Isophthalonitril | |
| DE60002020D1 (de) | Verfahren zur Herstellen von hochreinem Xylitol | |
| AU2003265052A1 (en) | Process for the purification of recombinant proteins from complex media and purified proteins obtained thereby | |
| DE59912502D1 (de) | Verfahren zur herstellung von enantiomerenreinem n-methyl- n- (1s)- 1-phenyl- 2-((3s)-3- hydroxypyrrolidin- 1-yl)ethyl]- 2,2- diphenylacetamid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1155120 Country of ref document: EP |