ATE332364T1 - Verfahren zur gewinnung von purifizierter virenzuammensetzung - Google Patents
Verfahren zur gewinnung von purifizierter virenzuammensetzungInfo
- Publication number
- ATE332364T1 ATE332364T1 AT00906444T AT00906444T ATE332364T1 AT E332364 T1 ATE332364 T1 AT E332364T1 AT 00906444 T AT00906444 T AT 00906444T AT 00906444 T AT00906444 T AT 00906444T AT E332364 T1 ATE332364 T1 AT E332364T1
- Authority
- AT
- Austria
- Prior art keywords
- purified virus
- virus composition
- obtaining purified
- viral
- particles
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title 1
- 230000003612 virological effect Effects 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 2
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9902167 | 1999-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332364T1 true ATE332364T1 (de) | 2006-07-15 |
Family
ID=9542357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00906444T ATE332364T1 (de) | 1999-02-22 | 2000-02-21 | Verfahren zur gewinnung von purifizierter virenzuammensetzung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7264958B1 (de) |
| EP (1) | EP1155120B1 (de) |
| JP (2) | JP4802366B2 (de) |
| AT (1) | ATE332364T1 (de) |
| AU (1) | AU774437B2 (de) |
| CA (1) | CA2364934C (de) |
| DE (1) | DE60029195T2 (de) |
| WO (1) | WO2000050573A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1073721B1 (de) | 1998-04-22 | 2005-08-31 | Genvec, Inc. | Effiziente reinigung von adenovirus |
| DK1407006T3 (da) * | 2001-12-20 | 2005-12-12 | Bavarian Nordic As | Fremgangsmåde til indvinding og oprensning af poxvirus fra inficerede celler |
| ES2356154T3 (es) | 2003-07-21 | 2011-04-05 | Transgene S.A. | Citoquinas multifuncionales. |
| JP2007522814A (ja) | 2004-02-23 | 2007-08-16 | クルセル ホランド ベー ヴェー | ウイルスの精製方法 |
| DK1869171T4 (en) | 2005-04-11 | 2016-01-18 | Crucell Holland Bv | Virus cleaning using ultrafiltration |
| JP4670583B2 (ja) * | 2005-10-20 | 2011-04-13 | チッソ株式会社 | 水溶性カチオン性磁気微粒子を用いた脂質ベシクルの分離又は検出方法 |
| AU2007272494B2 (en) | 2006-07-14 | 2011-07-28 | Wisconsin Alumni Research Foundation | Adsorptive membranes for trapping viruses |
| CA2675355C (en) | 2007-01-30 | 2015-04-28 | Transgene S.A. | Papillomavirus vaccine |
| CN102203242B (zh) | 2008-11-03 | 2013-06-12 | 克鲁塞尔荷兰公司 | 产生腺病毒载体的方法 |
| PL2382474T3 (pl) | 2009-01-20 | 2015-08-31 | Transgene Sa | Rozpuszczalny ICAM-1 jako biomarker do prognozowania odpowiedzi terapeutycznej |
| SG2014014021A (en) | 2009-03-24 | 2014-07-30 | Transgene Sa | Biomarker for monitoring patients |
| HRP20140262T1 (hr) | 2009-04-17 | 2014-04-25 | Transgene Sa | Biomarker za praä†enje pacijenata |
| MX337287B (es) | 2009-07-10 | 2016-02-22 | Transgene Sa | Biomarcador para seleccionar pacientes y metodos relacionados. |
| MX2012001592A (es) | 2009-08-07 | 2012-05-22 | Transgene Sa | Composicion para el tratamiento de la infección del virus de la hepatitis b. |
| EP2536829B1 (de) | 2010-02-15 | 2016-04-06 | Crucell Holland B.V. | Verfahren zur Herstellung von adenoviralen Ad26-Vektoren |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| EP2632562B1 (de) * | 2010-10-27 | 2020-08-05 | Philip Morris Products S.a.s. | Verfahren zur erfassung virusähnlicher partikel aus pflanzen unter verwendung von expansionsbett- chromatografie |
| EP3202897B1 (de) | 2010-12-09 | 2020-04-15 | Institut Pasteur | Diagnostische verwendung eines fusionspolypeptids, das ein virales protein und ein mgmt-enzym enthält |
| EP2747778B1 (de) | 2011-08-26 | 2017-12-06 | Wisconsin Alumni Research Foundation | Influenza-viren mit einem mutanten pb2-gensegment als lebende abgeschwächte impfstoffe |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
| TW201321016A (zh) | 2011-09-29 | 2013-06-01 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二) |
| WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
| EP2872172B1 (de) | 2012-07-10 | 2018-11-14 | Transgene SA | Impfstoff mit einem mykobakteriellen antigen |
| WO2014066443A1 (en) | 2012-10-23 | 2014-05-01 | Emory University | Gm-csf and il-4 conjugates, compositions, and methods related thereto |
| BR112015030881A2 (pt) | 2013-06-14 | 2017-10-24 | Psioxus Theraupeutics Ltd | regime de dosagem e formulações para adenovírus de tipo b |
| EP3831398A1 (de) | 2013-10-25 | 2021-06-09 | PsiOxus Therapeutics Limited | Onkolytische adenoviren, die mit heterologen genen ausgestattet sind |
| CA2936131A1 (en) | 2014-01-09 | 2015-07-16 | Transgene Sa | Fusion of heterooligomeric mycobacterial antigens |
| WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| CN107949397A (zh) | 2015-02-13 | 2018-04-20 | 特兰斯吉恩股份有限公司 | 免疫治疗疫苗和抗体组合治疗 |
| WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
| AU2016369485B2 (en) | 2015-12-17 | 2024-02-01 | Akamis Bio Limited | Group B adenovirus encoding an anti-TCR-complex antibody or fragment |
| AU2017221444B2 (en) | 2016-02-19 | 2021-07-29 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza B virus replication for vaccine development |
| US20190134190A1 (en) | 2016-05-04 | 2019-05-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
| CA3033267A1 (en) | 2016-08-29 | 2018-03-08 | Psioxus Therapeutics Limited | Adenovirus armed with bispecific t cell engager (bite) |
| GB201713765D0 (en) | 2017-08-28 | 2017-10-11 | Psioxus Therapeutics Ltd | Modified adenovirus |
| EP3522920A2 (de) | 2016-10-10 | 2019-08-14 | Transgene SA | Immuntherapeutisches produkt und mdsc-modulator-kombinationstherapie |
| CN110418650A (zh) | 2016-11-16 | 2019-11-05 | 免疫治疗有限公司 | 用于治疗过敏的核酸 |
| BR112019022108A2 (pt) | 2017-04-22 | 2020-05-12 | Immunomic Therapeutics, Inc. | Construções de lamp aprimoradas |
| KR20200016224A (ko) | 2017-05-02 | 2020-02-14 | 이뮤노믹 쎄라퓨틱스, 인크. | 암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물 |
| JP2021500891A (ja) | 2017-10-25 | 2021-01-14 | ウィスコンシン アルムニ リサーチ ファンデイション | 卵における複製のための安定化されたhaを有する組換えインフルエンザウイルス |
| GB201801614D0 (en) | 2018-01-31 | 2018-03-14 | Psioxus Therapeutics Ltd | Formulation |
| CA3100004A1 (en) | 2018-05-15 | 2019-11-21 | Immunomic Therapeutics, Inc. | Improved lamp constructs comprising allergens |
| US12343390B2 (en) | 2018-08-07 | 2025-07-01 | Wisconsin Alumni Research Foundation (Warf) | Recombinant biologically contained filovirus vaccine |
| JP7655849B2 (ja) | 2018-08-20 | 2025-04-02 | ウィスコンシン アルムニ リサーチ ファンデイション | ヘマグルチニン(ha)タンパク質内の非ドミナントエピトープに対する免疫応答を誘起するためのベクター |
| AU2019344006B2 (en) | 2018-09-21 | 2025-11-27 | University Of Connecticut | Compositions and methods to restore paternal UBE3A gene expression in human Angelman Syndrome |
| WO2020104691A1 (en) * | 2018-11-22 | 2020-05-28 | Fixed Phage Limited | Production of immobilised bacteriophage |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| US11851648B2 (en) | 2019-02-08 | 2023-12-26 | Wisconsin Alumni Research Foundation (Warf) | Humanized cell line |
| WO2020223699A1 (en) | 2019-05-01 | 2020-11-05 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
| GB201909081D0 (en) * | 2019-06-25 | 2019-08-07 | Psioxus Therapeutics Ltd | Method |
| US11807872B2 (en) | 2019-08-27 | 2023-11-07 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| AU2020366515A1 (en) | 2019-10-18 | 2022-04-21 | Immunomic Therapeutics, Inc. | Improved lamp constructs comprising cancer antigens |
| PH12022551208A1 (en) | 2019-11-18 | 2023-04-24 | Janssen Biotech Inc | Vaccines based on mutant calr and jak2 and their uses |
| WO2021150874A1 (en) | 2020-01-24 | 2021-07-29 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized na |
| TW202144389A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在多發性骨髓瘤中表現之新抗原及其用途 |
| TW202144388A (zh) | 2020-02-14 | 2021-12-01 | 美商健生生物科技公司 | 在卵巢癌中表現之新抗原及其用途 |
| US12290562B2 (en) | 2020-03-25 | 2025-05-06 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| JP2023521194A (ja) | 2020-04-13 | 2023-05-23 | ヤンセン バイオテツク,インコーポレーテツド | Psma及びsteap1ワクチン並びにそれらの使用 |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
| US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
| EP4176087A1 (de) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Verfahren zur bestimmung des ansprechens auf eine prostatakrebsbehandlung |
| US20230241530A1 (en) * | 2022-02-01 | 2023-08-03 | W. L. Gore & Associates, Inc. | Affinity chromatography devices containing a heat treated fibrillated polymer membrane for the separation of mrna and viral vectors from an aqueous mixture |
| EP4508071A1 (de) | 2022-04-10 | 2025-02-19 | Immunomic Therapeutics, Inc. | Bicistronische lampenkonstrukte mit immunreaktionserhöhenden genen und verfahren zur verwendung davon |
| WO2025158316A1 (en) | 2024-01-26 | 2025-07-31 | Janssen Biotech, Inc. | Ovarian neoantigens and use thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0328256A1 (de) * | 1988-01-21 | 1989-08-16 | Owens-Corning Fiberglas Corporation | Glasfaser, überzogen mit Agarose, zur Verwendung als Säulenpackung oder chromatographisches Medium in Biotrennungen |
| GB8806605D0 (en) | 1988-03-19 | 1988-04-20 | Robinson E | Composite adsorbents |
| SE9101149D0 (sv) | 1991-04-17 | 1991-04-17 | Pharmacia Lkb Biotech | Beads for down stream processing |
| DE4128953A1 (de) * | 1991-08-30 | 1993-03-04 | Basf Ag | Verfahren zur kultivierung von saeugerzellen im fliessbettreaktor |
| US5837520A (en) * | 1995-03-07 | 1998-11-17 | Canji, Inc. | Method of purification of viral vectors |
| FR2737730B1 (fr) | 1995-08-10 | 1997-09-05 | Pasteur Merieux Serums Vacc | Procede de purification de virus par chromatographie |
| WO1997008298A1 (en) * | 1995-08-30 | 1997-03-06 | Genzyme Corporation | Chromatographic purification of adenovirus and aav |
| US6027888A (en) * | 1996-04-05 | 2000-02-22 | Board Of Regents, The University Of Texas System | Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells |
| JP2000514290A (ja) | 1996-07-01 | 2000-10-31 | ローヌ―プーラン・ロレ・エス・アー | 組換えアデノウイルスの製造方法 |
| JP4492826B2 (ja) | 1996-11-20 | 2010-06-30 | イントロジェン セラピューティクス,インコーポレイテッド | アデノウイルスベクターの産生および精製のための改良された方法 |
| DE69739961D1 (de) | 1996-12-13 | 2010-09-23 | Schering Corp | Methoden zur Virus-Reinigung |
| SE9700383D0 (sv) * | 1997-02-04 | 1997-02-04 | Pharmacia Biotech Ab | An adsorption/separation method and a medium for adsorption/separation |
| AU2583099A (en) | 1998-02-04 | 1999-08-23 | Sun Microsystems, Inc. | Method and apparatus for efficient authentication and integrity checking using hierarchical hashing |
| EP1073721B1 (de) | 1998-04-22 | 2005-08-31 | Genvec, Inc. | Effiziente reinigung von adenovirus |
-
2000
- 2000-02-21 DE DE60029195T patent/DE60029195T2/de not_active Expired - Lifetime
- 2000-02-21 EP EP00906444A patent/EP1155120B1/de not_active Expired - Lifetime
- 2000-02-21 AU AU28118/00A patent/AU774437B2/en not_active Expired
- 2000-02-21 AT AT00906444T patent/ATE332364T1/de active
- 2000-02-21 US US09/914,036 patent/US7264958B1/en not_active Expired - Lifetime
- 2000-02-21 JP JP2000601137A patent/JP4802366B2/ja not_active Expired - Lifetime
- 2000-02-21 CA CA2364934A patent/CA2364934C/fr not_active Expired - Lifetime
- 2000-02-21 WO PCT/FR2000/000430 patent/WO2000050573A1/fr not_active Ceased
-
2011
- 2011-01-20 JP JP2011009922A patent/JP2011120596A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2364934C (fr) | 2011-10-18 |
| JP2002536992A (ja) | 2002-11-05 |
| JP2011120596A (ja) | 2011-06-23 |
| US7264958B1 (en) | 2007-09-04 |
| WO2000050573A1 (fr) | 2000-08-31 |
| EP1155120A1 (de) | 2001-11-21 |
| EP1155120B1 (de) | 2006-07-05 |
| DE60029195T2 (de) | 2007-06-28 |
| CA2364934A1 (fr) | 2000-08-31 |
| AU2811800A (en) | 2000-09-14 |
| JP4802366B2 (ja) | 2011-10-26 |
| AU774437B2 (en) | 2004-06-24 |
| DE60029195D1 (de) | 2006-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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