NO20000439L - Kombinasjoner av HMG-COA reduktase inhibitorer og nikotinsyreforbindelser samt metoder for behandling av hyperlipidemi - Google Patents

Kombinasjoner av HMG-COA reduktase inhibitorer og nikotinsyreforbindelser samt metoder for behandling av hyperlipidemi

Info

Publication number
NO20000439L
NO20000439L NO20000439A NO20000439A NO20000439L NO 20000439 L NO20000439 L NO 20000439L NO 20000439 A NO20000439 A NO 20000439A NO 20000439 A NO20000439 A NO 20000439A NO 20000439 L NO20000439 L NO 20000439L
Authority
NO
Norway
Prior art keywords
nicotinic acid
nicotinamide
methyl
hmg
combinations
Prior art date
Application number
NO20000439A
Other languages
English (en)
Norwegian (no)
Other versions
NO20000439D0 (no
Inventor
David J Bova
Josephine Dunne
Original Assignee
Kos Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kos Pharma Inc filed Critical Kos Pharma Inc
Publication of NO20000439D0 publication Critical patent/NO20000439D0/no
Publication of NO20000439L publication Critical patent/NO20000439L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO20000439A 1997-07-31 2000-01-27 Kombinasjoner av HMG-COA reduktase inhibitorer og nikotinsyreforbindelser samt metoder for behandling av hyperlipidemi NO20000439L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90375297A 1997-07-31 1997-07-31
PCT/US1998/015990 WO1999006035A2 (fr) 1997-07-31 1998-07-31 COMBINAISONS D'INHIBITEURS DE REDUCTASE HMG-CoA ET DE COMPOSES D'ACIDE NICOTINIQUE ET PROCEDES DE TRAITEMENT DE L'HYPERLIPIDEMIE, UNE FOIS PAR JOUR LE SOIR

Publications (2)

Publication Number Publication Date
NO20000439D0 NO20000439D0 (no) 2000-01-27
NO20000439L true NO20000439L (no) 2000-03-22

Family

ID=25418027

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000439A NO20000439L (no) 1997-07-31 2000-01-27 Kombinasjoner av HMG-COA reduktase inhibitorer og nikotinsyreforbindelser samt metoder for behandling av hyperlipidemi

Country Status (17)

Country Link
US (3) US20040053975A1 (fr)
EP (2) EP1017390B1 (fr)
JP (2) JP4870869B2 (fr)
AT (2) ATE359785T1 (fr)
AU (1) AU752673B2 (fr)
BR (1) BR9815548A (fr)
CA (1) CA2298549C (fr)
CY (1) CY1107057T1 (fr)
DE (2) DE69837610T2 (fr)
DK (1) DK1017390T3 (fr)
ES (2) ES2336492T3 (fr)
HK (1) HK1106153A1 (fr)
IL (2) IL134271A0 (fr)
NO (1) NO20000439L (fr)
NZ (1) NZ520176A (fr)
PT (1) PT1017390E (fr)
WO (1) WO1999006035A2 (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE970731A1 (en) 1997-10-07 2000-10-04 Fuisz Internat Ltd Product and method for the treatment of hyperlipidemia
DE19858789A1 (de) * 1998-12-18 2000-06-21 Bayer Ag Kombination von Cerivastatin und Fibraten
US6569461B1 (en) 1999-03-08 2003-05-27 Merck & Co., Inc. Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
AU774636B2 (en) * 1999-07-14 2004-07-01 Genzyme Corporation Fat-binding polymers, optionally combined with lipase inhibitors
JP2001131151A (ja) * 1999-11-02 2001-05-15 Shionogi & Co Ltd オレフィン誘導体の新規用途
IL139450A0 (en) * 1999-11-10 2001-11-25 Pfizer Prod Inc Methods of administering apo b-secretion/mtp inhibitors
AU2000250960A1 (en) 2000-06-09 2001-12-17 Lek Pharmaceuticals D.D. Stable pharmaceutical product and formulation
US6916849B2 (en) 2000-10-23 2005-07-12 Sankyo Company, Limited Compositions for improving lipid content in the blood
AU2001295991A1 (en) * 2000-10-23 2002-05-06 Sankyo Company Limited Compositions for improving lipids in blood
CA2428204A1 (fr) * 2000-11-07 2002-05-16 Sankyo Company, Limited Compositions permettant de reduire la concentration de peroxydes lipidiques
TWI284529B (en) * 2000-12-18 2007-08-01 Sankyo Co A composition for lowering triglyceride
ITMI20012366A1 (it) * 2001-11-09 2003-05-09 Farmatron Ltd Sistemi terapeutici stabilizzati a rilascio immediato e/o modificato per la somministrazione orale di principi attivi e/o eccipienti e/o ali
US7176310B1 (en) 2002-04-09 2007-02-13 Ucb Sa Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents
CA2494801A1 (fr) * 2002-08-02 2004-02-12 Sankyo Company Limited Composition medicamenteuse contenant un inhibiteur de hmg-coa reductase
JP4607436B2 (ja) * 2002-08-02 2011-01-05 第一三共株式会社 HMG−CoAリダクターゼ阻害剤を含有する医薬組成物
CN100415235C (zh) * 2002-08-02 2008-09-03 三共株式会社 含有HMG-CoA还原酶抑制剂的药物组合物
SI21402A (sl) 2003-02-12 2004-08-31 LEK farmacevtska dru�ba d.d. Obloženi delci in farmacevtske oblike
AR041089A1 (es) * 2003-05-15 2005-05-04 Merck & Co Inc Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas
MXPA06001506A (es) * 2003-08-04 2006-05-15 Pfizer Prod Inc Formas de dosificacion de inhibidores de la proteina de transferencia de colesteril ester e inhibidores de la hmg-coa reductasa.
EP1684704A2 (fr) * 2003-10-29 2006-08-02 Raif M. Tawakol Compositions et procedes pour augmenter les niveaux de hdl et hdl-2b
US20070014833A1 (en) * 2005-03-30 2007-01-18 Sirtris Pharmaceuticals, Inc. Treatment of eye disorders with sirtuin modulators
WO2006105440A2 (fr) * 2005-03-30 2006-10-05 Sirtris Pharmaceuticals, Inc. Nicotinamide riboside et analogues
US20060292099A1 (en) * 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
US20070149466A1 (en) * 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
US20070021379A1 (en) * 2005-07-11 2007-01-25 Pharmena North America Inc. Methylnicotinamide derivatives and formulations for treatment of lipoprotein abnormalities
KR20070063350A (ko) * 2005-12-14 2007-06-19 주식회사종근당 서방형 방출층과 속방형 방출층을 포함한 고지혈증 및동맥경화를 치료를 위한 약제학적 조성물
CA2569776A1 (fr) * 2006-02-17 2007-08-17 Kos Life Sciences, Inc. Formulation de niacine provoquant de faibles symptomes de bouffee congestive
US8784886B2 (en) 2006-03-09 2014-07-22 GlaxoSmithKline, LLC Coating capsules with active pharmaceutical ingredients
EP2081550B2 (fr) * 2006-03-09 2021-05-26 Reliant Pharmaceuticals, Inc. Revêtement de capsules avec des ingrédients pharmaceutiques actifs
WO2008023958A1 (fr) * 2006-08-24 2008-02-28 Hanall Pharmaceutical Co., Ltd. Composition pharmaceutique combinée à libération contrôlée comprenant de la dihydropyridine, des bloqueurs de canal calcium et des inhibiteurs de l'hgm-coa réductase
WO2008023869A1 (fr) * 2006-08-24 2008-02-28 Hanall Pharmaceutical Co., Ltd. PRÉPARATION PHARMACEUTIQUE COMBINÉE À LIBÉRATION CONTRÔLÉE COMPRENANT DES INHIBITEURS CALCIQUES À BASE DE DIHYDROPYRIDINE ET DES INHIBITEURS DE HMG-CoA RÉDUCTASE
DE102007003524A1 (de) * 2007-01-19 2008-09-04 MEDICE Arzneimittel Pütter GmbH & Co. KG Arzneimittel zur Behandlung und/oder Prävention von Arteriosklerose
KR100885029B1 (ko) 2007-02-07 2009-02-23 지엘팜텍 주식회사 경구투여용 서방성 삼중정제
WO2009016577A2 (fr) * 2007-07-27 2009-02-05 Ranbaxy Laboratories Limited Composition pharmaceutique comprenant de l'atorvastatine et de la niacine
EP2255796A2 (fr) * 2008-02-22 2010-12-01 HanAll Biopharma Co., Ltd. Préparation pharmaceutique
US20110052683A1 (en) * 2008-02-22 2011-03-03 Hanall Biopharma Co., Ltd. Pharmaceutical preparation for treating cardiovascular disease
WO2009104932A2 (fr) * 2008-02-22 2009-08-27 한올제약주식회사 Préparation composite
EP2303327A2 (fr) * 2008-05-20 2011-04-06 Cerenis Therapeutics S.A. Thérapie combinée associant niacine et anti-inflammatoire non stéroïdien (nsaid)
BRPI0913425A2 (pt) * 2008-06-02 2015-11-24 Reddys Lab Ltd Dr formulações de niacina com liberação modificada
WO2009149056A2 (fr) * 2008-06-02 2009-12-10 Dr. Reddy's Laboratories Ltd. Combinaisons de niacine et d'un oxicame
US20100178341A1 (en) * 2008-06-11 2010-07-15 Ranbaxy Laboratories Limited BILAYERED TABLET COMPRISING NIACIN AND HMG-CoA REDUCTASE INHIBITOR
EP2310004A1 (fr) * 2008-07-11 2011-04-20 Kareus Therapeutics SA Compositions de niacine pour la réduction de la production de peptide amyloïde bêta-42(a 42)et pour le traitement de la maladie d'alzheimer (ad)
JP5845173B2 (ja) * 2009-05-01 2016-01-20 アデア ファーマスーティカルズ,インコーポレイテッド 非オピオイドおよびオピオイド鎮痛薬の組み合わせを含む口腔内崩壊錠組成物
CA2706270C (fr) * 2010-06-03 2020-01-07 Accucaps Industries Limited Formulations pharmaceutiques de statines et d'acides gras omega-3 pour encapsulation
JP6055465B2 (ja) 2011-05-20 2016-12-27 アストラゼネカ・ユーケイ・リミテッドAstraZeneca UK Limited ロスバスタチンカルシウムの医薬組成物
KR20170083535A (ko) 2014-11-14 2017-07-18 젬파이어 세러퓨틱스 인코포레이티드 α,ω-다이카복실산-말단 다이알케인 에터를 제조하기 위한 방법 및 중간체
BR112018007857A2 (pt) * 2015-11-06 2018-10-30 Gemphire Therapeutics Inc combinações de gemcabene para o tratamento de doença cardiovascular

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3524001A (en) * 1965-03-04 1970-08-11 Upjohn Co Compositions and method for reducing free fatty acid and cholesterol in the blood of mammals with 3,5 - disubstituted isoxazoles
JPS63310827A (ja) * 1987-06-15 1988-12-19 Sanwa Kagaku Kenkyusho Co Ltd ニコチン酸誘導体を主剤とする徐放性製剤
US5260305A (en) * 1988-12-12 1993-11-09 E. R. Squibb & Sons, Inc. Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination
US4933165A (en) * 1989-01-18 1990-06-12 Merck & Co., Inc. Coenzyme Q10 with HMG-CoA reductase inhibitors
US5268181A (en) * 1989-04-13 1993-12-07 Upsher-Smith Laboratories, Inc. Method of using niacin to control nocturnal cholesterol synthesis
CA2016467A1 (fr) * 1989-06-05 1990-12-05 Martin Eisman Methode de traitement de l'atherosclerose des vaisseaux peripheriques a l'aide d'un inhibiteur de l'hmg coa reductase et (ou) d'un inhibiteur de la squalene synthetase
CA2018470A1 (fr) * 1989-07-17 1991-01-17 Scott Adams Biller Inhibiteurs de la synthetase de la squalene contenant du soufre, et methode pour ceux-ci
US5135935A (en) * 1991-05-17 1992-08-04 Merck & Co., Inc. Squalene synthetase inhibitors
US5840339A (en) * 1991-07-30 1998-11-24 Kunin; Robert Blood cholesterol reducing pharmaceutical composition
EP0543417A1 (fr) * 1991-11-22 1993-05-26 Lipogenics, Incorporated Tocotriènols et composés sembles à tocotriènol et méthodes pour leur utilisation
US5292534A (en) * 1992-03-25 1994-03-08 Valentine Enterprises, Inc. Sustained release composition and method utilizing xanthan gum and an active ingredient
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
US6129930A (en) * 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6080428A (en) * 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6369103B1 (en) * 1994-01-18 2002-04-09 Bristol-Myers Squibb Company Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
US5582838A (en) * 1994-12-22 1996-12-10 Merck & Co., Inc. Controlled release drug suspension delivery device
US5773453A (en) * 1995-04-19 1998-06-30 Vanderbilt University Methods for administration of antilipemic drugs
CA2218696A1 (fr) * 1995-04-19 1996-10-24 L. Jackson Ii Roberts Compositions, trousses et procedes d'administration d'antilipemiques et medicaments contre l'agregation plaquettaire

Also Published As

Publication number Publication date
WO1999006035A2 (fr) 1999-02-11
NO20000439D0 (no) 2000-01-27
JP4870869B2 (ja) 2012-02-08
US20040053975A1 (en) 2004-03-18
EP1792616B1 (fr) 2009-12-16
BR9815548A (pt) 2000-11-07
CY1107057T1 (el) 2012-10-24
JP2009235105A (ja) 2009-10-15
PT1017390E (pt) 2007-07-24
DK1017390T3 (da) 2007-06-11
ES2283067T3 (es) 2007-10-16
ATE359785T1 (de) 2007-05-15
EP1017390A2 (fr) 2000-07-12
US20090226518A1 (en) 2009-09-10
AU752673B2 (en) 2002-09-26
DE69837610T2 (de) 2008-01-03
AU8680198A (en) 1999-02-22
CA2298549C (fr) 2006-01-10
NZ520176A (en) 2005-02-25
JP2001511444A (ja) 2001-08-14
ES2336492T3 (es) 2010-04-13
EP1017390B1 (fr) 2007-04-18
EP1792616A1 (fr) 2007-06-06
DE69837610D1 (de) 2007-05-31
HK1106153A1 (en) 2008-03-07
WO1999006035A3 (fr) 1999-04-22
IL134271A0 (en) 2001-04-30
DE69841395D1 (de) 2010-01-28
US20120164221A1 (en) 2012-06-28
CA2298549A1 (fr) 1999-02-11
IL134271A (en) 2006-07-05
ATE451926T1 (de) 2010-01-15

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