NO20053581L - Optisk aktivt dihydropyridinderivat. - Google Patents

Optisk aktivt dihydropyridinderivat.

Info

Publication number
NO20053581L
NO20053581L NO20053581A NO20053581A NO20053581L NO 20053581 L NO20053581 L NO 20053581L NO 20053581 A NO20053581 A NO 20053581A NO 20053581 A NO20053581 A NO 20053581A NO 20053581 L NO20053581 L NO 20053581L
Authority
NO
Norway
Prior art keywords
optically active
dihydropyridine derivative
active dihydropyridine
ester
derivative
Prior art date
Application number
NO20053581A
Other languages
English (en)
Other versions
NO331384B1 (no
Inventor
Toshio Sada
Takashi Kobayashi
Original Assignee
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ube Industries filed Critical Ube Industries
Publication of NO20053581L publication Critical patent/NO20053581L/no
Publication of NO331384B1 publication Critical patent/NO331384B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Et optisk aktivt dihydropyirdinderivat ifølge foreliggende oppfinnelse er (R)-2-amino-l,4-dihydro-6-metyl-4-(3 -nitrofenyl)-3,5 -pyridindikarboksylsyre-3 -(1-difenylmety lazetidin-3 -yl)-ester-5 -isopropy lester eller et farmasøytisk akseptabelt salt derav.
NO20053581A 2002-12-24 2005-07-22 Optisk aktivt dihydropyridinderivat, preventivt eller terapeutisk middel som inneholder derivatet og anvendelse av derivatet for fremstilling av et medikament for forhindring eller behandling av en sykdom i sirkulasjonssystemet. NO331384B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002371901 2002-12-24
PCT/JP2003/016616 WO2004058745A1 (ja) 2002-12-24 2003-12-24 光学活性なジヒドロピリジン誘導体

Publications (2)

Publication Number Publication Date
NO20053581L true NO20053581L (no) 2005-07-22
NO331384B1 NO331384B1 (no) 2011-12-12

Family

ID=32677216

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053581A NO331384B1 (no) 2002-12-24 2005-07-22 Optisk aktivt dihydropyridinderivat, preventivt eller terapeutisk middel som inneholder derivatet og anvendelse av derivatet for fremstilling av et medikament for forhindring eller behandling av en sykdom i sirkulasjonssystemet.

Country Status (16)

Country Link
US (2) US20050272715A1 (no)
EP (1) EP1577309A4 (no)
KR (1) KR101008871B1 (no)
CN (1) CN100549005C (no)
AU (1) AU2003296091B2 (no)
BR (1) BR0317671A (no)
CA (1) CA2511595C (no)
IL (1) IL169163A (no)
MX (1) MXPA05006885A (no)
NO (1) NO331384B1 (no)
NZ (1) NZ540845A (no)
PL (1) PL375996A1 (no)
RU (1) RU2294328C2 (no)
TW (1) TWI341312B (no)
WO (1) WO2004058745A1 (no)
ZA (1) ZA200505110B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100352818C (zh) * 2005-09-23 2007-12-05 四川科伦药业股份有限公司 一种改进的制备阿折地平的方法
TW200736245A (en) * 2005-11-29 2007-10-01 Sankyo Co Acid addition salts of optically active dihydropyridine derivatives
TW200806648A (en) * 2005-11-29 2008-02-01 Sankyo Co Acid addition salts of dihydropyridine derivatives
JP2008290989A (ja) * 2007-05-28 2008-12-04 Ube Ind Ltd ジヒドロピリジン誘導体の酸付加塩を含有する医薬
CN101591329B (zh) * 2009-07-03 2013-12-25 北京华禧联合科技发展有限公司 一种制备手性阿折地平及其可接受盐的方法
CN102503833B (zh) * 2011-10-12 2013-11-27 北京汉典中西药研究开发中心 2-(3-硝基亚苄基)乙酰乙酸异丙酯的制备方法
DE102013020666B4 (de) * 2013-11-29 2017-09-14 Staedtler Mars Gmbh & Co. Kg Bleimine für Schreib-, Zeichen- und/oder Malgeräte sowie Verfahren zu deren Herstellung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772596A (en) * 1986-10-09 1988-09-20 Sankyo Company Limited Dihydropyridine derivatives, their preparation and their use
JPH0331715A (ja) 1989-06-29 1991-02-12 Hazama Gumi Ltd 測点の変位自動計測方法及びその装置
JP3491506B2 (ja) * 1997-10-14 2004-01-26 宇部興産株式会社 ジヒドロピリジン誘導体の製造法
EP1285655B1 (en) * 2000-04-11 2007-05-30 Sankyo Company, Limited Stabilized pharmaceutical compositions containing the calcium channel blocker azelnidipine
JP2004505061A (ja) * 2000-07-27 2004-02-19 ファルマシア・コーポレーション うっ血性心不全の処置のための、エポキシ−ステロイド型アルドステロン拮抗薬とカルシウムチャンネル遮断薬の併用療法

Also Published As

Publication number Publication date
CA2511595C (en) 2012-04-17
NZ540845A (en) 2008-02-29
MXPA05006885A (es) 2005-08-16
AU2003296091B2 (en) 2007-07-19
US20080287411A1 (en) 2008-11-20
CN1753885A (zh) 2006-03-29
CN100549005C (zh) 2009-10-14
EP1577309A1 (en) 2005-09-21
BR0317671A (pt) 2005-11-29
WO2004058745A1 (ja) 2004-07-15
NO331384B1 (no) 2011-12-12
EP1577309A4 (en) 2007-01-24
RU2005119970A (ru) 2006-01-20
IL169163A (en) 2012-01-31
PL375996A1 (en) 2005-12-12
AU2003296091A1 (en) 2004-07-22
TW200424192A (en) 2004-11-16
KR20050088203A (ko) 2005-09-02
TWI341312B (en) 2011-05-01
ZA200505110B (en) 2006-03-29
US7795281B2 (en) 2010-09-14
KR101008871B1 (ko) 2011-01-17
CA2511595A1 (en) 2004-07-15
RU2294328C2 (ru) 2007-02-27
IL169163A0 (en) 2007-07-04
AU2003296091A8 (en) 2004-07-22
US20050272715A1 (en) 2005-12-08

Similar Documents

Publication Publication Date Title
NO20053581L (no) Optisk aktivt dihydropyridinderivat.
TR200100432T2 (tr) Hepatit C inhibitörü tri-peptidler
RS51444B (sr) JEDINJENJA KOJA SADRŽE LAKTAM I NJIHOVI DERIVATI KAO INHIBITORI FAKTORA Xa
NO20044731L (no) Kinolin- og isokinolinderivater fremgangsmate for fremstilling derav og anvendelse derav som betennelseshemmere
DK2311818T3 (da) Kombination af en 5-phenylthiazolforbindelse som PI3-kinasehæmmer med et antiinflammatorisk, bronchodilatorisk eller antihistaminisk medikament
PE20060243A1 (es) Derivados de 4-amino insustituido-5-(4-urea-fenil)-pirrolotriazina
DK1569899T3 (da) Substituerede 3-alkyl- og 3-arylalkyl-1H-indol-1-yl-eddikesyrederivater som inhibitorer af plasminogenaktivator-inhibitor-1 (PAI-1)
NO950297L (no) Prolinamidderivater
NO20030885D0 (no) Inhibitorer av <alfa>4 styrt celleadhesjon
DK1435915T3 (da) Orale doseringsformer til propiverin eller farmaceutisk acceptable salte deraf med en forsinket afgivelse af en aktiv bestanddel
DK0923554T3 (da) N-Benzylpiperidin- og tetrahydropyridinderivater
EE200000659A (et) 4-(3,5-bis-trifluorometüülbensüülamino)-2-etüül-6-trifluorometüül-3,4-dihüdro-2H-kin oliin-1-karboksüülhappe etüülestrid või nende soolad ja valmistamise meetodid
NO20034311L (no) CCR5-antagonister for behandling av AIDS
DK1611144T3 (da) Derivater af 2-(8,9-dioxo-2,6-diazabicyclo(5.2.0)non-1(7)-en-2-yl)alkyl-phosphonsyre og deres avendelse som n-methyl-D-aspartat (NMDA)-receptor-antagonister
DOP2002000399A (es) Nuevos derivados de acido sulfonico
FI882001A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten substituoitujen 2-(2-aminoetoksimetyyli)-4-(2-kloorifenyyli)-3-etoksikarbonyyli-5-metoksikarbonyyli-6-metyyli-1,4-dihydropyridiinien valmistamiseksi
NO20051282L (no) Antitumorale analoger av lamellariner.
AR036864A1 (es) Uso de compuestos de acido benzacepin-n-acetico, y procedimiento para la preparacion de dichos compuestos
WO2004037796A3 (en) 1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives
DE60027144D1 (de) Hydroxamsäure-derivate
TW200736245A (en) Acid addition salts of optically active dihydropyridine derivatives
DK1043310T3 (da) Biphenylamidinderivater
EA200300272A1 (ru) Новые производные хиназолина, способ их получения и фармацевтические композиции, содержащие их
NO20063058L (no) Fremgangsmate for fremstilling av (3-okso-2,3-dihydro-1H-isoindol-1-yl)acetylguanidinderivater
DE69828390D1 (de) Diaminotrifluoromethylpyrimidinderivate enthaltende antikrebs-zusammensetzung

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees