NO180195C - Analogifremgangsmåte ved fremstilling av heksahydroazepinderivater - Google Patents

Analogifremgangsmåte ved fremstilling av heksahydroazepinderivater

Info

Publication number
NO180195C
NO180195C NO912283A NO912283A NO180195C NO 180195 C NO180195 C NO 180195C NO 912283 A NO912283 A NO 912283A NO 912283 A NO912283 A NO 912283A NO 180195 C NO180195 C NO 180195C
Authority
NO
Norway
Prior art keywords
preparation
analogous process
hexahydroazepine
derivatives
hexahydroazepine derivatives
Prior art date
Application number
NO912283A
Other languages
English (en)
Norwegian (no)
Other versions
NO180195B (no
NO912283D0 (no
NO912283L (no
Inventor
Serge Lavastre
Jean-Pierre Maignan
Raymond Paul
Martine Poncelet
Vincent Santucci
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO912283D0 publication Critical patent/NO912283D0/no
Publication of NO912283L publication Critical patent/NO912283L/no
Publication of NO180195B publication Critical patent/NO180195B/no
Publication of NO180195C publication Critical patent/NO180195C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
NO912283A 1990-06-14 1991-06-13 Analogifremgangsmåte ved fremstilling av heksahydroazepinderivater NO180195C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909007434A FR2663328B1 (fr) 1990-06-14 1990-06-14 Derives d'hexahydroazepines, un procede pour leur preparation et compositions pharmaceutiques les contenant.

Publications (4)

Publication Number Publication Date
NO912283D0 NO912283D0 (no) 1991-06-13
NO912283L NO912283L (no) 1991-12-16
NO180195B NO180195B (no) 1996-11-25
NO180195C true NO180195C (no) 1997-03-05

Family

ID=9397608

Family Applications (1)

Application Number Title Priority Date Filing Date
NO912283A NO180195C (no) 1990-06-14 1991-06-13 Analogifremgangsmåte ved fremstilling av heksahydroazepinderivater

Country Status (30)

Country Link
US (2) US5231092A (hu)
EP (1) EP0461986B1 (hu)
JP (1) JP2620422B2 (hu)
KR (1) KR100213531B1 (hu)
AT (1) ATE132861T1 (hu)
AU (1) AU647481B2 (hu)
BR (1) BR1100207A (hu)
CA (1) CA2044484C (hu)
CZ (1) CZ285696B6 (hu)
DE (1) DE69116237T2 (hu)
DK (1) DK0461986T3 (hu)
ES (1) ES2084792T3 (hu)
FI (1) FI101301B1 (hu)
FR (1) FR2663328B1 (hu)
GR (1) GR3019197T3 (hu)
HK (1) HK1000598A1 (hu)
HU (2) HU222490B1 (hu)
IE (1) IE74709B1 (hu)
IL (1) IL98479A (hu)
LT (1) LT3550B (hu)
LV (1) LV10433B (hu)
MX (1) MX9203360A (hu)
MY (1) MY135774A (hu)
NO (1) NO180195C (hu)
NZ (1) NZ238516A (hu)
PL (1) PL165842B1 (hu)
PT (1) PT97944B1 (hu)
RU (2) RU2133741C1 (hu)
UA (1) UA27222C2 (hu)
ZA (1) ZA914572B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751645B1 (fr) * 1996-07-29 1998-12-24 Sanofi Sa Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales
US6005102A (en) 1997-10-15 1999-12-21 American Home Products Corporation Aryloxy-alkyl-dialkylamines
FR2794742B1 (fr) 1999-06-11 2005-06-03 Sanofi Synthelabo Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant
FR2795724B1 (fr) * 1999-07-02 2002-12-13 Sanofi Synthelabo Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
EP2314289A1 (en) 2005-10-31 2011-04-27 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
KR101478855B1 (ko) 2007-05-30 2015-01-02 인드-스위프트 래버러토리즈 리미티드 이바브라딘 히드로클로라이드 및 그의 다형태의 제조방법
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN116437960A (zh) 2020-09-17 2023-07-14 梅莱蒂奥斯治疗 用于治疗病毒感染的化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881165A (en) * 1956-06-29 1959-04-07 Nl Combinatie Chem Ind alpha-alpha-diphenyl-gamma-hexamethyleneiminobutyramide
DE1545561A1 (de) * 1965-08-23 1969-12-11 Acraf Verfahren zur Herstellung von pharmakologisch aktiven N,N-disubstituierten 1-Aryl-3-aminopropinen
GB1475314A (en) 1973-11-02 1977-06-01 Cm Ind Phenyl-propylamine derivatives
US4104383A (en) * 1973-11-02 1978-08-01 C M Industries Derivatives of phenylpropenylamine
DE3019497A1 (de) * 1980-05-22 1981-11-26 Bayer Ag, 5090 Leverkusen Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
AU4261285A (en) * 1984-06-01 1985-12-05 Tokyo Tanabe Company Limited 1-propanone derivatives
DE3508398A1 (de) * 1985-03-08 1986-11-06 Hoechst Ag, 6230 Frankfurt Fungizide mittel auf der basis von 3-(hetero)-arylpropylaminen sowie neue (hetero)-aryl-propylamine und verfahren zu ihrer herstellung
US4709094A (en) 1986-07-10 1987-11-24 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Sigma brain receptor ligands and their use

Also Published As

Publication number Publication date
EP0461986A1 (fr) 1991-12-18
AU7843491A (en) 1991-12-19
PT97944A (pt) 1992-03-31
ATE132861T1 (de) 1996-01-15
MX9203360A (es) 1992-07-01
FI912899A0 (fi) 1991-06-14
US5231092A (en) 1993-07-27
IE74709B1 (en) 1997-07-30
HUT61736A (en) 1993-03-01
LV10433B (en) 1995-08-20
IL98479A0 (en) 1992-07-15
PL165842B1 (pl) 1995-02-28
HU211616A9 (en) 1995-12-28
PT97944B (pt) 1998-11-30
LV10433A (lv) 1995-02-20
IE911963A1 (en) 1991-12-18
HK1000598A1 (en) 1998-04-09
HU9101983D0 (en) 1991-12-30
ES2084792T3 (es) 1996-05-16
FR2663328A1 (fr) 1991-12-20
JP2620422B2 (ja) 1997-06-11
PL290675A1 (en) 1992-03-23
RU2133741C1 (ru) 1999-07-27
FI912899A (fi) 1991-12-15
RU94038042A (ru) 1996-09-10
LT3550B (en) 1995-11-27
CA2044484C (en) 1998-05-26
DE69116237D1 (de) 1996-02-22
FR2663328B1 (fr) 1994-08-05
GR3019197T3 (en) 1996-06-30
NO180195B (no) 1996-11-25
NO912283D0 (no) 1991-06-13
JPH04321676A (ja) 1992-11-11
PT97944B1 (pt) 1999-05-31
IL98479A (en) 1995-11-27
RU2070194C1 (ru) 1996-12-10
US5296596A (en) 1994-03-22
EP0461986B1 (fr) 1996-01-10
UA27222C2 (uk) 2000-08-15
CA2044484A1 (en) 1991-12-15
DK0461986T3 (da) 1996-05-28
KR100213531B1 (ko) 1999-08-02
ZA914572B (en) 1992-03-25
LTIP704A (en) 1995-01-31
CZ285696B6 (cs) 1999-10-13
MY135774A (en) 2008-06-30
NZ238516A (en) 1993-09-27
FI101301B (fi) 1998-05-29
KR920000728A (ko) 1992-01-29
HU222490B1 (hu) 2003-07-28
DE69116237T2 (de) 1996-07-25
FI101301B1 (fi) 1998-05-29
NO912283L (no) 1991-12-16
BR1100207A (pt) 1999-10-05
CZ181891A3 (en) 1994-01-19
AU647481B2 (en) 1994-03-24

Similar Documents

Publication Publication Date Title
NO991019D0 (no) 3-merkapto-1-(1,3-tiazolin-2-yl)azetidin-derivater
DE10199052I1 (de) Neue substituierte Alkandiphosphonsaeuren
NO180195C (no) Analogifremgangsmåte ved fremstilling av heksahydroazepinderivater
HU9201626D0 (en) Process for the production of 3-amino-piridazines
ATE115580T1 (de) Verfahren und zwischenprodukte zur herstellung von azabicyclo(2.2.2>octan-3-iminen.
DE59108921D1 (de) Acyl-(2'-hydroxybiphenyl-2-yl)-phosphinsäuresalze, ihre herstellung und verwendung
ATE170862T1 (de) 5-ht3 pyrrolopyrazinderivate
DE69928610D1 (de) Verfahren zur Herstellung von 2-Carbamoyl-Pyridinen
HUT50833A (en) Process for producing indolo/3,2-1-de/ /1,4/-oxazino/2,3,4-ij/ /1,5/-naphthyridine derivatives
ATE67194T1 (de) Thiadiazolylacetamid-derivate, verfahren zu ihrer herstellung und ihre verwendung.
DE69127396T2 (de) Verfahren zur Herstellung von Dihydrofuranonderivaten
AR247567A1 (es) Procedimiento para preparar carbonitrilos azatetraciclicos