NO180106B - Innretning for kontrollert avgivelse av nikotin og anvendelse derav - Google Patents
Innretning for kontrollert avgivelse av nikotin og anvendelse derav Download PDFInfo
- Publication number
- NO180106B NO180106B NO891509A NO891509A NO180106B NO 180106 B NO180106 B NO 180106B NO 891509 A NO891509 A NO 891509A NO 891509 A NO891509 A NO 891509A NO 180106 B NO180106 B NO 180106B
- Authority
- NO
- Norway
- Prior art keywords
- nicotine
- hot
- melt adhesive
- adhesive
- reservoir
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title claims abstract description 65
- 229960002715 nicotine Drugs 0.000 title claims abstract description 65
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title claims abstract description 65
- 238000013270 controlled release Methods 0.000 title description 2
- 239000004831 Hot glue Substances 0.000 claims abstract description 37
- 239000000853 adhesive Substances 0.000 claims abstract description 16
- 230000001070 adhesive effect Effects 0.000 claims abstract description 16
- 239000000945 filler Substances 0.000 claims description 12
- 239000013032 Hydrocarbon resin Substances 0.000 claims description 10
- 229920006270 hydrocarbon resin Polymers 0.000 claims description 10
- 239000010410 layer Substances 0.000 claims description 10
- 230000032683 aging Effects 0.000 claims description 9
- 239000011814 protection agent Substances 0.000 claims description 9
- 150000001298 alcohols Chemical class 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 6
- 241000607479 Yersinia pestis Species 0.000 claims description 5
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 239000004014 plasticizer Substances 0.000 claims description 4
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims description 4
- 239000011241 protective layer Substances 0.000 claims description 4
- VSKJLJHPAFKHBX-UHFFFAOYSA-N 2-methylbuta-1,3-diene;styrene Chemical compound CC(=C)C=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 VSKJLJHPAFKHBX-UHFFFAOYSA-N 0.000 claims description 3
- 229920002367 Polyisobutene Polymers 0.000 claims description 3
- 230000003712 anti-aging effect Effects 0.000 claims description 3
- 238000009826 distribution Methods 0.000 claims description 3
- 229920001610 polycaprolactone Polymers 0.000 claims description 3
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 239000004814 polyurethane Substances 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 2
- 239000002574 poison Substances 0.000 claims description 2
- 231100000614 poison Toxicity 0.000 claims description 2
- 229920000647 polyepoxide Polymers 0.000 claims description 2
- 229920001289 polyvinyl ether Polymers 0.000 claims description 2
- 230000000241 respiratory effect Effects 0.000 claims description 2
- 239000000463 material Substances 0.000 abstract description 12
- 238000000034 method Methods 0.000 abstract description 8
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 238000009828 non-uniform distribution Methods 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 238000009827 uniform distribution Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 description 11
- KBAYQFWFCOOCIC-GNVSMLMZSA-N [(1s,4ar,4bs,7s,8ar,10ar)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,7,8,8a,9,10,10a-dodecahydrophenanthren-1-yl]methanol Chemical compound OC[C@@]1(C)CCC[C@]2(C)[C@H]3CC[C@H](C(C)C)C[C@H]3CC[C@H]21 KBAYQFWFCOOCIC-GNVSMLMZSA-N 0.000 description 8
- 235000014113 dietary fatty acids Nutrition 0.000 description 8
- 150000002148 esters Chemical class 0.000 description 8
- 229930195729 fatty acid Natural products 0.000 description 8
- 239000000194 fatty acid Substances 0.000 description 8
- 150000004665 fatty acids Chemical class 0.000 description 8
- 235000013311 vegetables Nutrition 0.000 description 8
- 229920005989 resin Polymers 0.000 description 7
- 239000011347 resin Substances 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 238000001704 evaporation Methods 0.000 description 4
- 230000008020 evaporation Effects 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 239000000155 melt Substances 0.000 description 3
- 230000005586 smoking cessation Effects 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 2
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 description 2
- 101800000989 Oxytocin Proteins 0.000 description 2
- 102100031951 Oxytocin-neurophysin 1 Human genes 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 239000005038 ethylene vinyl acetate Substances 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 description 2
- 229960001723 oxytocin Drugs 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 208000007848 Alcoholism Diseases 0.000 description 1
- 229920004939 Cariflex™ Polymers 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 1
- 206010057852 Nicotine dependence Diseases 0.000 description 1
- 229920005987 OPPANOL® Polymers 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 238000003723 Smelting Methods 0.000 description 1
- 208000025569 Tobacco Use disease Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 201000007930 alcohol dependence Diseases 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000315 carcinogenic Toxicity 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000012936 correction and preventive action Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 206010013663 drug dependence Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 239000004632 polycaprolactone Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 238000010345 tape casting Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000009974 thixotropic effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 239000003039 volatile agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Materials Engineering (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3729165 | 1987-09-01 | ||
| DE19873743947 DE3743947A1 (de) | 1987-09-01 | 1987-12-23 | Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung |
| PCT/DE1988/000479 WO1989001789A1 (en) | 1987-09-01 | 1988-08-03 | Device for controlled release of nicotine, process for manufacturing it, and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO891509D0 NO891509D0 (no) | 1989-04-12 |
| NO891509L NO891509L (no) | 1989-04-12 |
| NO180106B true NO180106B (no) | 1996-11-11 |
Family
ID=25859262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO891509A NO180106B (no) | 1987-09-01 | 1989-04-12 | Innretning for kontrollert avgivelse av nikotin og anvendelse derav |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5411739A (fi) |
| EP (1) | EP0305757B1 (fi) |
| JP (1) | JP2718531B2 (fi) |
| KR (1) | KR970006447B1 (fi) |
| AT (1) | ATE98877T1 (fi) |
| AU (1) | AU613945B2 (fi) |
| CA (1) | CA1333052C (fi) |
| CZ (1) | CZ278699B6 (fi) |
| DE (2) | DE3743947A1 (fi) |
| DK (1) | DK210389A (fi) |
| ES (1) | ES2047511T3 (fi) |
| FI (1) | FI96482C (fi) |
| HU (1) | HU205255B (fi) |
| IE (1) | IE66100B1 (fi) |
| IL (1) | IL87540A (fi) |
| MY (1) | MY104817A (fi) |
| NO (1) | NO180106B (fi) |
| NZ (1) | NZ225917A (fi) |
| PH (1) | PH25355A (fi) |
| PL (1) | PL274487A1 (fi) |
| PT (1) | PT88380B (fi) |
| SK (1) | SK277941B6 (fi) |
| WO (1) | WO1989001789A1 (fi) |
| YU (1) | YU47291B (fi) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4781924A (en) | 1987-11-09 | 1988-11-01 | Alza Corporation | Transdermal drug delivery device |
| PT90820B (pt) * | 1988-06-14 | 1995-05-31 | Alza Corp | Dispositivo de libertacao transdermica sub-saturado |
| US5004610A (en) * | 1988-06-14 | 1991-04-02 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
| DE4031881C2 (de) * | 1990-10-08 | 1994-02-24 | Sanol Arznei Schwarz Gmbh | Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung |
| DE4224325C1 (de) * | 1992-07-23 | 1994-02-10 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster für niedrigschmelzende und/oder flüchtige Wirkstoffe und Verfahren zu seiner Herstellung |
| FR2739031B1 (fr) * | 1995-09-27 | 1997-11-21 | Lhd Lab Hygiene Dietetique | Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique |
| US5730721A (en) | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
| DE19825499C2 (de) | 1998-06-08 | 2003-07-17 | Beiersdorf Ag | Wirkstoffhaltige Pflaster |
| DE19834496B4 (de) | 1998-07-31 | 2004-02-26 | Beiersdorf Ag | Verbesserte Freisetzung von Ibuprofen aus Heißschmelzklebemassen in wirkstoffhaltigen Pflastern durch Zusatz von pharmazeutischen Hilfsstoffen und Verwendung von Hilfsstoffen zur Verbesserung der Freisetzung von Ibuprofen |
| PT1140039E (pt) | 1998-12-18 | 2010-02-03 | Alza Corp | Dispositivos transparentes de administração transdérmica de nicotina |
| US6974588B1 (en) | 1999-12-07 | 2005-12-13 | Elan Pharma International Limited | Transdermal patch for delivering volatile liquid drugs |
| FR2810237B1 (fr) | 2000-06-15 | 2002-07-26 | Oreal | Composition cosmetique filmogene |
| FR2810239B1 (fr) | 2000-06-15 | 2002-12-20 | Oreal | Composition cosmetique filmogene |
| FR2810238B1 (fr) | 2000-06-15 | 2002-07-19 | Oreal | Composition cosmetique filmogene |
| DE10118282A1 (de) * | 2001-04-12 | 2002-12-05 | Lohmann Therapie Syst Lts | Haftkleber auf Basis von Ethylen-Vinylacetat-Copolymeren und Klebharzen, für medizinische Verwendungszwecke |
| EP1469814B9 (fr) * | 2002-01-24 | 2008-11-05 | L'oreal | Composition comprenant un melange de polymeres semi-cristallins et une huile volatile |
| DE10212864B4 (de) | 2002-03-22 | 2005-12-22 | Beiersdorf Ag | Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung |
| JP2004277345A (ja) * | 2003-03-17 | 2004-10-07 | Daikyo Yakuhin Kogyo Kk | 硬膏剤及びその製造法 |
| DE10360592A1 (de) * | 2003-12-19 | 2005-07-28 | Beiersdorf Ag | Pflastersystem zur Verabreichung von Antihistaminika |
| DE102004039728A1 (de) * | 2004-08-16 | 2006-02-23 | Beiersdorf Ag | Wirkstoffhaltiges Tape zur Behandlung von Gelenkerkrankungen |
| DE102004040840A1 (de) * | 2004-08-23 | 2006-03-02 | Henkel Kgaa | Wärmeleitfähige Haftklebstoffe |
| DE102005053909A1 (de) | 2005-05-13 | 2006-11-16 | Beiersdorf Ag | Selbstklebende Hautauflage und Kombinationsset zur kosmetischen Hautpflege |
| CA2609612C (en) * | 2005-05-23 | 2014-09-23 | President & Fellows Of Harvard College | Use of huperzine to treat epilepsy |
| ES2622738T3 (es) | 2005-12-07 | 2017-07-07 | The Procter & Gamble Company | Composiciones poliméricas para la liberación sostenida de materiales volátiles |
| US8399007B2 (en) * | 2006-12-05 | 2013-03-19 | Landec Corporation | Method for formulating a controlled-release pharmaceutical formulation |
| EP2114414B1 (en) | 2006-12-21 | 2013-11-06 | Trustees Of Tufts College | Synthetic lipophilic inositol glycans for treatment of cancer and glucose-metabolism disorders |
| US20110224245A1 (en) * | 2008-09-04 | 2011-09-15 | President And Fellows Of Harvard College | Treatment Of Neurological Disorders Using Huperzine |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE606885C (de) * | 1933-09-14 | 1934-12-12 | American Ball Mill Company | Auswechselbare Ausfuetterung, z. B. fuer Rohrmuehlen |
| JPS54138124A (en) * | 1978-04-19 | 1979-10-26 | Hisamitsu Pharmaceut Co Inc | Novel plaster and its preparation |
| JPS6034922B2 (ja) * | 1978-09-01 | 1985-08-12 | 久光製薬株式会社 | 新規貼付薬 |
| GB2045618B (en) * | 1979-04-03 | 1983-05-11 | Hisamitsu Pharmaceutical Co | Adhesive plaster |
| JPS55141408A (en) * | 1979-04-19 | 1980-11-05 | Hisamitsu Pharmaceut Co Inc | Novel plaster containing steroid and its production |
| JPS6059207B2 (ja) * | 1981-03-13 | 1985-12-24 | 日東電工株式会社 | 複合製剤の製法 |
| GB2118040A (en) * | 1982-02-15 | 1983-10-26 | Hoechst Uk Ltd | Oral anti-diabetic preparation |
| JPS58141225A (ja) * | 1982-02-16 | 1983-08-22 | Takasago Corp | 芳香材用樹脂組成物 |
| JPS58189112A (ja) * | 1982-04-30 | 1983-11-04 | Nitto Electric Ind Co Ltd | 生理活性物質含有物の製法 |
| DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
| AU560710B2 (en) * | 1983-04-27 | 1987-04-16 | Lohmann Gmbh & Co. Kg. | Pharmaceutical product |
| US4564364A (en) * | 1983-05-26 | 1986-01-14 | Alza Corporation | Active agent dispenser |
| DE3586707T2 (de) * | 1984-10-05 | 1993-02-11 | Hercon Lab | System zur transdermalen applikation eines arzneimittels. |
| DE3438284A1 (de) * | 1984-10-16 | 1985-03-07 | Hans-Harald von 2400 Lübeck Tilly | Nikotinhaltiges depotpflaster |
| EP0186019B1 (de) * | 1984-12-22 | 1993-10-06 | Schwarz Pharma Ag | Wirkstoffpflaster |
| US4597961A (en) * | 1985-01-23 | 1986-07-01 | Etscorn Frank T | Transcutaneous application of nicotine |
| JPS61251619A (ja) * | 1985-04-30 | 1986-11-08 | Nitto Electric Ind Co Ltd | ニコチン含有テ−プ製剤 |
| US4714655A (en) * | 1985-10-04 | 1987-12-22 | Avery International Corporation | Pressure-sensitive adhesive containing heat-sensitive materials, and method of making the same |
| DE3629304A1 (de) * | 1986-08-28 | 1988-03-24 | Lohmann Gmbh & Co Kg | Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung |
| US4840796A (en) * | 1988-04-22 | 1989-06-20 | Dow Corning Corporation | Block copolymer matrix for transdermal drug release |
-
1987
- 1987-12-23 DE DE19873743947 patent/DE3743947A1/de active Granted
-
1988
- 1988-08-03 IE IE255688A patent/IE66100B1/en not_active IP Right Cessation
- 1988-08-03 JP JP63506545A patent/JP2718531B2/ja not_active Expired - Lifetime
- 1988-08-03 EP EP88112631A patent/EP0305757B1/de not_active Revoked
- 1988-08-03 HU HU884780A patent/HU205255B/hu not_active IP Right Cessation
- 1988-08-03 ES ES88112631T patent/ES2047511T3/es not_active Expired - Lifetime
- 1988-08-03 AT AT88112631T patent/ATE98877T1/de active
- 1988-08-03 WO PCT/DE1988/000479 patent/WO1989001789A1/de active IP Right Grant
- 1988-08-03 NZ NZ225917A patent/NZ225917A/en unknown
- 1988-08-03 DE DE88112631T patent/DE3886477D1/de not_active Revoked
- 1988-08-03 AU AU21396/88A patent/AU613945B2/en not_active Ceased
- 1988-08-03 KR KR1019890700765A patent/KR970006447B1/ko not_active IP Right Cessation
- 1988-08-10 MY MYPI88000913A patent/MY104817A/en unknown
- 1988-08-14 PH PH37413A patent/PH25355A/en unknown
- 1988-08-19 CA CA000575203A patent/CA1333052C/en not_active Expired - Lifetime
- 1988-08-23 IL IL8754088A patent/IL87540A/en not_active IP Right Cessation
- 1988-08-31 SK SK5874-88A patent/SK277941B6/sk unknown
- 1988-08-31 PT PT88380A patent/PT88380B/pt not_active IP Right Cessation
- 1988-08-31 CZ CS885874A patent/CZ278699B6/cs not_active IP Right Cessation
- 1988-09-01 YU YU166488A patent/YU47291B/sh unknown
- 1988-09-01 PL PL27448788A patent/PL274487A1/xx unknown
-
1989
- 1989-04-12 NO NO891509A patent/NO180106B/no not_active Application Discontinuation
- 1989-04-28 DK DK210389A patent/DK210389A/da not_active Application Discontinuation
- 1989-04-28 FI FI892055A patent/FI96482C/fi not_active IP Right Cessation
-
1994
- 1994-05-03 US US08/237,322 patent/US5411739A/en not_active Expired - Lifetime
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| FC2A | Withdrawal, rejection or dismissal of laid open patent application |