NO179838C - Fremgangsmåte for fremstilling av S-(-)-3-morfolino-4-(3-tert-butylamino-2-hydroksypropoksy)-1,2,5-tiadiazol-hemihydrat - Google Patents

Fremgangsmåte for fremstilling av S-(-)-3-morfolino-4-(3-tert-butylamino-2-hydroksypropoksy)-1,2,5-tiadiazol-hemihydrat

Info

Publication number
NO179838C
NO179838C NO911508A NO911508A NO179838C NO 179838 C NO179838 C NO 179838C NO 911508 A NO911508 A NO 911508A NO 911508 A NO911508 A NO 911508A NO 179838 C NO179838 C NO 179838C
Authority
NO
Norway
Prior art keywords
hydroxypropoxy
butylamino
morpholino
tert
preparation
Prior art date
Application number
NO911508A
Other languages
English (en)
Norwegian (no)
Other versions
NO911508L (no
NO911508D0 (no
NO179838B (no
Inventor
Markku Peraelampi
Original Assignee
Leiras Oy
Huhtamaeki Yhthymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy, Huhtamaeki Yhthymae Oy filed Critical Leiras Oy
Publication of NO911508L publication Critical patent/NO911508L/no
Publication of NO911508D0 publication Critical patent/NO911508D0/no
Publication of NO179838B publication Critical patent/NO179838B/no
Publication of NO179838C publication Critical patent/NO179838C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/101,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Control Of El Displays (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO911508A 1988-10-20 1991-04-17 Fremgangsmåte for fremstilling av S-(-)-3-morfolino-4-(3-tert-butylamino-2-hydroksypropoksy)-1,2,5-tiadiazol-hemihydrat NO179838C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI884838A FI82240C (fi) 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
PCT/FI1989/000196 WO1990004592A1 (en) 1988-10-20 1989-10-13 Novel s-timolol derivative and process for its preparation

Publications (4)

Publication Number Publication Date
NO911508L NO911508L (no) 1991-04-17
NO911508D0 NO911508D0 (no) 1991-04-17
NO179838B NO179838B (no) 1996-09-16
NO179838C true NO179838C (no) 1996-12-27

Family

ID=8527232

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911508A NO179838C (no) 1988-10-20 1991-04-17 Fremgangsmåte for fremstilling av S-(-)-3-morfolino-4-(3-tert-butylamino-2-hydroksypropoksy)-1,2,5-tiadiazol-hemihydrat

Country Status (12)

Country Link
US (4) US5231095A (de)
EP (1) EP0440684B1 (de)
JP (1) JP2949508B2 (de)
AT (1) ATE112277T1 (de)
AU (1) AU624431B2 (de)
CA (1) CA2001083C (de)
DE (1) DE68918597T2 (de)
DK (1) DK175377B1 (de)
FI (1) FI82240C (de)
NO (1) NO179838C (de)
NZ (1) NZ231057A (de)
WO (1) WO1990004592A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US5496820A (en) * 1988-10-20 1996-03-05 Peraelampi; Markku Ophthalmic use of S-timolol hemihydrate
TW208013B (de) * 1990-03-01 1993-06-21 Daiichi Co Ltd
DK0577913T3 (da) 1992-07-08 1998-01-26 Santen Oy Ophthalmisk præparat indeholdende timolol-hemihydrat
US20060143783A1 (en) * 2004-12-15 2006-07-06 Berman Paul K Energy diffusing glove insert
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
CN101622243B (zh) 2007-02-28 2013-12-04 旭化成制药株式会社 磺酰胺衍生物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
US4428883A (en) * 1981-03-06 1984-01-31 The University Of Kentucky Research Foundation Novel method of administering β-blockers and novel dosage forms containing same
FI71933C (fi) * 1984-03-30 1989-04-06 Star Oy Ab Nya l-vinsyra-0-monoestrar av 3-morfolino-4-(3'-tert.-butylamino-2'-hydroxipropoxi)-1,2,5-tiadiazol och deras anvaendning saosom mellanprodukter.
JPS60226855A (ja) * 1984-04-26 1985-11-12 Nippon Kayaku Co Ltd N−ベンジルオキシカルボニル−l−スレオニンアミド・1/2水和物およびその製造法
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Also Published As

Publication number Publication date
FI884838A (fi) 1990-04-21
FI82240C (fi) 1991-02-11
AU624431B2 (en) 1992-06-11
US5231095A (en) 1993-07-27
EP0440684A1 (de) 1991-08-14
NZ231057A (en) 1990-11-27
DK175377B1 (da) 2004-09-20
DE68918597D1 (de) 1994-11-03
CA2001083A1 (en) 1990-04-20
FI82240B (fi) 1990-10-31
DK72591D0 (da) 1991-04-19
US5541184A (en) 1996-07-30
JPH04502612A (ja) 1992-05-14
NO911508L (no) 1991-04-17
ATE112277T1 (de) 1994-10-15
NO911508D0 (no) 1991-04-17
JP2949508B2 (ja) 1999-09-13
NO179838B (no) 1996-09-16
US5574035A (en) 1996-11-12
FI884838A0 (fi) 1988-10-20
US5354860A (en) 1994-10-11
DK72591A (da) 1991-04-19
EP0440684B1 (de) 1994-09-28
CA2001083C (en) 1999-06-15
WO1990004592A1 (en) 1990-05-03
DE68918597T2 (de) 1995-05-11
AU4347389A (en) 1990-05-14

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