NO179707C - Analogifremgangsmåte for fremstilling av antipicornavirale pyridazinaminer - Google Patents

Analogifremgangsmåte for fremstilling av antipicornavirale pyridazinaminer

Info

Publication number
NO179707C
NO179707C NO905541A NO905541A NO179707C NO 179707 C NO179707 C NO 179707C NO 905541 A NO905541 A NO 905541A NO 905541 A NO905541 A NO 905541A NO 179707 C NO179707 C NO 179707C
Authority
NO
Norway
Prior art keywords
antipicornaviral
4alkyl
compounds
preparation
analogous process
Prior art date
Application number
NO905541A
Other languages
English (en)
Norwegian (no)
Other versions
NO179707B (no
NO905541L (no
NO905541D0 (no
Inventor
Raymond Antoine Stokbroekx
Marcel Gerebernus Maria Luyckx
Gilbert Arthur Jules Grauwels
Cyriel Alphons Maria Va Eycken
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO905541D0 publication Critical patent/NO905541D0/no
Publication of NO905541L publication Critical patent/NO905541L/no
Publication of NO179707B publication Critical patent/NO179707B/no
Publication of NO179707C publication Critical patent/NO179707C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO905541A 1989-12-26 1990-12-21 Analogifremgangsmåte for fremstilling av antipicornavirale pyridazinaminer NO179707C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45639589A 1989-12-26 1989-12-26
US51063590A 1990-04-18 1990-04-18

Publications (4)

Publication Number Publication Date
NO905541D0 NO905541D0 (no) 1990-12-21
NO905541L NO905541L (no) 1991-06-27
NO179707B NO179707B (no) 1996-08-26
NO179707C true NO179707C (no) 1996-12-04

Family

ID=27038209

Family Applications (1)

Application Number Title Priority Date Filing Date
NO905541A NO179707C (no) 1989-12-26 1990-12-21 Analogifremgangsmåte for fremstilling av antipicornavirale pyridazinaminer

Country Status (30)

Country Link
EP (1) EP0435381B1 (de)
JP (1) JP3157174B2 (de)
KR (1) KR0183968B1 (de)
CN (1) CN1037268C (de)
AT (1) ATE129711T1 (de)
AU (2) AU635100B2 (de)
BG (1) BG60591B1 (de)
CA (1) CA2031889A1 (de)
CZ (1) CZ281251B6 (de)
DE (1) DE69023321T2 (de)
DK (1) DK0435381T3 (de)
ES (1) ES2078297T3 (de)
FI (1) FI96949C (de)
GR (1) GR3018430T3 (de)
HR (1) HRP930482A2 (de)
HU (1) HUT59398A (de)
IE (1) IE69845B1 (de)
IL (1) IL96770A (de)
JO (1) JO1645B1 (de)
MY (1) MY106065A (de)
NO (1) NO179707C (de)
NZ (1) NZ236446A (de)
PH (1) PH27523A (de)
PL (1) PL165497B1 (de)
PT (1) PT96361B (de)
RO (1) RO108867B1 (de)
RU (1) RU2051149C1 (de)
TN (1) TNSN90159A1 (de)
YU (1) YU48137B (de)
ZW (1) ZW20190A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2099630A1 (en) * 1992-07-02 1994-01-03 Guy Dominic Diana Heterocyclyl-phenoxyalkyl-piperidinylpyridazines as antiviral agents
US5242924A (en) * 1992-07-02 1993-09-07 Sterling Winthrop Inc. Tetrazolyl-(phenoxy and phenoxyalkyl)-piperidinylpyridazines as antiviral agents
US5364865A (en) * 1992-12-30 1994-11-15 Sterling Winthrop Inc. Phenoxy- and phenoxyalkyl-piperidines as antiviral agents
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
ZA97288B (en) * 1996-01-15 1998-07-14 Janssen Pharmaceutica Nv Angiogenesis inhibiting pyridazinamines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
EP1102755B1 (de) 1998-08-07 2006-01-04 Chiron Corporation Subtituierte isoxazole derivate als estrogen rezeptor modulatore
AUPR213700A0 (en) 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
US7790720B2 (en) * 2005-03-31 2010-09-07 Ucb Pharma, S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
WO2007046867A2 (en) * 2005-05-19 2007-04-26 Xenon Pharmaceuticals Inc. Piperidine derivatives and their uses as therapeutic agents
WO2007003962A2 (en) * 2005-06-30 2007-01-11 Prosidion Limited Gpcr agonists
CN1887875B (zh) * 2005-06-30 2011-04-06 深圳市东阳光实业发展有限公司 哒嗪胺衍生物及其用于制备小rna病毒抑制剂的用途
GB0713602D0 (en) 2007-07-12 2007-08-22 Syngenta Participations Ag Chemical compounds
CN101450049A (zh) 2007-12-07 2009-06-10 辉凌国际制药(瑞士)有限公司 药物组合物
CN102344416B (zh) 2010-08-02 2015-09-16 中国人民解放军军事医学科学院毒物药物研究所 哒嗪衍生物及其作为抗小rna病毒感染药物的用途
KR101726819B1 (ko) * 2014-10-27 2017-04-13 동아에스티 주식회사 Gpr119 작용 활성을 갖는 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약제학적 조성물
WO2016068453A1 (en) * 2014-10-27 2016-05-06 Dong-A St Co., Ltd. Compound having gpr119 agonistic activity, method for preparing the same, and pharmaceutical composition including the same as effective component

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
NZ225045A (en) * 1987-07-01 1990-06-26 Janssen Pharmaceutica Nv Antiviral pharmaceutical compositions containing cyclodextrin and an antiviral agent
MY104343A (en) * 1987-11-23 1994-03-31 Janssen Pharmaceutica Nv Novel pyridizinamine deravatives
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
NZ233526A (en) * 1989-05-15 1991-09-25 Janssen Pharmaceutica Nv Pyridazine derivatives and their pharmaceutical compositions
NZ233503A (en) * 1989-05-15 1991-06-25 Janssen Pharmaceutica Nv Substituted (thio)morpholinyl and piperazinyl alkylphenol ethers

Also Published As

Publication number Publication date
JP3157174B2 (ja) 2001-04-16
PL165497B1 (pl) 1994-12-30
GR3018430T3 (en) 1996-03-31
KR0183968B1 (ko) 1999-05-01
PH27523A (en) 1993-08-18
ATE129711T1 (de) 1995-11-15
ZW20190A1 (en) 1992-07-08
AU639865B2 (en) 1993-08-05
DE69023321D1 (de) 1995-12-07
DE69023321T2 (de) 1996-03-28
HU908413D0 (en) 1991-07-29
TNSN90159A1 (fr) 1991-03-05
IE69845B1 (en) 1996-10-02
FI906312A (fi) 1991-06-27
MY106065A (en) 1995-03-31
DK0435381T3 (da) 1996-02-19
IE904688A1 (en) 1991-07-17
NZ236446A (en) 1992-04-28
NO179707B (no) 1996-08-26
FI906312A0 (fi) 1990-12-20
CN1037268C (zh) 1998-02-04
ES2078297T3 (es) 1995-12-16
HUT59398A (en) 1992-05-28
EP0435381B1 (de) 1995-11-02
AU3113793A (en) 1993-03-11
PT96361A (pt) 1991-09-30
CN1052857A (zh) 1991-07-10
PL288406A1 (en) 1992-06-01
CZ281251B6 (cs) 1996-07-17
IL96770A0 (en) 1991-09-16
JPH04128283A (ja) 1992-04-28
AU635100B2 (en) 1993-03-11
FI96949C (fi) 1996-09-25
FI96949B (fi) 1996-06-14
AU6841890A (en) 1991-07-04
CA2031889A1 (en) 1991-06-27
IL96770A (en) 1995-01-24
YU244790A (sh) 1993-05-28
RO108867B1 (ro) 1994-09-30
YU48137B (sh) 1997-05-28
NO905541L (no) 1991-06-27
BG60591B1 (bg) 1995-09-29
HRP930482A2 (en) 1997-04-30
KR910011849A (ko) 1991-08-07
NO905541D0 (no) 1990-12-21
CZ640190A3 (en) 1996-04-17
RU2051149C1 (ru) 1995-12-27
PT96361B (pt) 1998-06-30
JO1645B1 (en) 1991-11-27
EP0435381A1 (de) 1991-07-03

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NO179707C (no) Analogifremgangsmåte for fremstilling av antipicornavirale pyridazinaminer
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