GR3018430T3 - Antipicornaviral pyridazinamines. - Google Patents

Antipicornaviral pyridazinamines.

Info

Publication number
GR3018430T3
GR3018430T3 GR950403560T GR950403560T GR3018430T3 GR 3018430 T3 GR3018430 T3 GR 3018430T3 GR 950403560 T GR950403560 T GR 950403560T GR 950403560 T GR950403560 T GR 950403560T GR 3018430 T3 GR3018430 T3 GR 3018430T3
Authority
GR
Greece
Prior art keywords
4alkyl
compounds
antipicornaviral
halo
chem
Prior art date
Application number
GR950403560T
Other languages
English (en)
Inventor
Raymond Antoine Stokbroekx
Marcel Gerebermus Maria Luyckx
Gilbert Arthur Jules Grauwels
Der Eycken Cyriel Alphons Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of GR3018430T3 publication Critical patent/GR3018430T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
GR950403560T 1989-12-26 1995-12-15 Antipicornaviral pyridazinamines. GR3018430T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45639589A 1989-12-26 1989-12-26
US51063590A 1990-04-18 1990-04-18

Publications (1)

Publication Number Publication Date
GR3018430T3 true GR3018430T3 (en) 1996-03-31

Family

ID=27038209

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950403560T GR3018430T3 (en) 1989-12-26 1995-12-15 Antipicornaviral pyridazinamines.

Country Status (30)

Country Link
EP (1) EP0435381B1 (el)
JP (1) JP3157174B2 (el)
KR (1) KR0183968B1 (el)
CN (1) CN1037268C (el)
AT (1) ATE129711T1 (el)
AU (2) AU635100B2 (el)
BG (1) BG60591B1 (el)
CA (1) CA2031889A1 (el)
CZ (1) CZ281251B6 (el)
DE (1) DE69023321T2 (el)
DK (1) DK0435381T3 (el)
ES (1) ES2078297T3 (el)
FI (1) FI96949C (el)
GR (1) GR3018430T3 (el)
HR (1) HRP930482A2 (el)
HU (1) HUT59398A (el)
IE (1) IE69845B1 (el)
IL (1) IL96770A (el)
JO (1) JO1645B1 (el)
MY (1) MY106065A (el)
NO (1) NO179707C (el)
NZ (1) NZ236446A (el)
PH (1) PH27523A (el)
PL (1) PL165497B1 (el)
PT (1) PT96361B (el)
RO (1) RO108867B1 (el)
RU (1) RU2051149C1 (el)
TN (1) TNSN90159A1 (el)
YU (1) YU48137B (el)
ZW (1) ZW20190A1 (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2099630A1 (en) * 1992-07-02 1994-01-03 Guy Dominic Diana Heterocyclyl-phenoxyalkyl-piperidinylpyridazines as antiviral agents
US5242924A (en) * 1992-07-02 1993-09-07 Sterling Winthrop Inc. Tetrazolyl-(phenoxy and phenoxyalkyl)-piperidinylpyridazines as antiviral agents
US5364865A (en) * 1992-12-30 1994-11-15 Sterling Winthrop Inc. Phenoxy- and phenoxyalkyl-piperidines as antiviral agents
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
AU717744B2 (en) * 1996-01-15 2000-03-30 Janssen Pharmaceutica N.V. Angiogenesis inhibiting pyridazinamines
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
ES2255294T3 (es) 1998-08-07 2006-06-16 Chiron Corporation Derivados de isoxazol sustituidos como moduladores del receptor de estrogenos.
AUPR213700A0 (en) 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
AU2006228690A1 (en) 2005-03-31 2006-10-05 Ucb Pharma S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
WO2007046867A2 (en) * 2005-05-19 2007-04-26 Xenon Pharmaceuticals Inc. Piperidine derivatives and their uses as therapeutic agents
NZ564759A (en) * 2005-06-30 2011-08-26 Prosidion Ltd GPCR agonists
CN1887875B (zh) * 2005-06-30 2011-04-06 深圳市东阳光实业发展有限公司 哒嗪胺衍生物及其用于制备小rna病毒抑制剂的用途
GB0713602D0 (en) * 2007-07-12 2007-08-22 Syngenta Participations Ag Chemical compounds
CN101450049A (zh) * 2007-12-07 2009-06-10 辉凌国际制药（瑞士）有限公司 药物组合物
CN102344416B (zh) * 2010-08-02 2015-09-16 中国人民解放军军事医学科学院毒物药物研究所 哒嗪衍生物及其作为抗小rna病毒感染药物的用途
WO2016068453A1 (en) * 2014-10-27 2016-05-06 Dong-A St Co., Ltd. Compound having gpr119 agonistic activity, method for preparing the same, and pharmaceutical composition including the same as effective component
KR101726819B1 (ko) * 2014-10-27 2017-04-13 동아에스티 주식회사 Gpr119 작용 활성을 갖는 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 약제학적 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
NZ225045A (en) * 1987-07-01 1990-06-26 Janssen Pharmaceutica Nv Antiviral pharmaceutical compositions containing cyclodextrin and an antiviral agent
MY104343A (en) * 1987-11-23 1994-03-31 Janssen Pharmaceutica Nv Novel pyridizinamine deravatives
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
NZ233503A (en) * 1989-05-15 1991-06-25 Janssen Pharmaceutica Nv Substituted (thio)morpholinyl and piperazinyl alkylphenol ethers
NZ233526A (en) * 1989-05-15 1991-09-25 Janssen Pharmaceutica Nv Pyridazine derivatives and their pharmaceutical compositions

Also Published As

Publication number Publication date
PT96361A (pt) 1991-09-30
AU3113793A (en) 1993-03-11
TNSN90159A1 (fr) 1991-03-05
AU6841890A (en) 1991-07-04
FI906312A0 (fi) 1990-12-20
ZW20190A1 (en) 1992-07-08
HUT59398A (en) 1992-05-28
DE69023321T2 (de) 1996-03-28
NO179707C (no) 1996-12-04
CN1037268C (zh) 1998-02-04
NZ236446A (en) 1992-04-28
KR910011849A (ko) 1991-08-07
IE69845B1 (en) 1996-10-02
KR0183968B1 (ko) 1999-05-01
CN1052857A (zh) 1991-07-10
AU635100B2 (en) 1993-03-11
IL96770A (en) 1995-01-24
IL96770A0 (en) 1991-09-16
ES2078297T3 (es) 1995-12-16
DK0435381T3 (da) 1996-02-19
NO179707B (no) 1996-08-26
JPH04128283A (ja) 1992-04-28
IE904688A1 (en) 1991-07-17
YU244790A (sh) 1993-05-28
CA2031889A1 (en) 1991-06-27
FI96949C (fi) 1996-09-25
PL288406A1 (en) 1992-06-01
AU639865B2 (en) 1993-08-05
FI906312A (fi) 1991-06-27
MY106065A (en) 1995-03-31
EP0435381A1 (en) 1991-07-03
JP3157174B2 (ja) 2001-04-16
RO108867B1 (ro) 1994-09-30
DE69023321D1 (de) 1995-12-07
FI96949B (fi) 1996-06-14
CZ281251B6 (cs) 1996-07-17
PH27523A (en) 1993-08-18
CZ640190A3 (en) 1996-04-17
HU908413D0 (en) 1991-07-29
RU2051149C1 (ru) 1995-12-27
PL165497B1 (pl) 1994-12-30
EP0435381B1 (en) 1995-11-02
HRP930482A2 (en) 1997-04-30
YU48137B (sh) 1997-05-28
NO905541L (no) 1991-06-27
PT96361B (pt) 1998-06-30
JO1645B1 (en) 1991-11-27
BG60591B1 (bg) 1995-09-29
NO905541D0 (no) 1990-12-21
ATE129711T1 (de) 1995-11-15

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