NO179044C - Fremgangsmåte for fremstilling av et glykosaminoglykanmodifisert protein - Google Patents

Fremgangsmåte for fremstilling av et glykosaminoglykanmodifisert protein

Info

Publication number
NO179044C
NO179044C NO904378A NO904378A NO179044C NO 179044 C NO179044 C NO 179044C NO 904378 A NO904378 A NO 904378A NO 904378 A NO904378 A NO 904378A NO 179044 C NO179044 C NO 179044C
Authority
NO
Norway
Prior art keywords
glycosaminoglycan
modified protein
preparation
protein
glycosaminoglycan modified
Prior art date
Application number
NO904378A
Other languages
English (en)
Other versions
NO904378D0 (no
NO179044B (no
NO904378L (no
Inventor
Katsukiyo Sakurai
Kyosuke Miyazaki
Original Assignee
Seikagaku Kogyo Kk Seikagaku C
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Kk Seikagaku C, Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Kk Seikagaku C
Publication of NO904378D0 publication Critical patent/NO904378D0/no
Publication of NO904378L publication Critical patent/NO904378L/no
Publication of NO179044B publication Critical patent/NO179044B/no
Publication of NO179044C publication Critical patent/NO179044C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
NO904378A 1990-03-30 1990-10-10 Fremgangsmåte for fremstilling av et glykosaminoglykanmodifisert protein NO179044C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2081163A JP2975632B2 (ja) 1990-03-30 1990-03-30 グリコサミノグリカン修飾プロテイン

Publications (4)

Publication Number Publication Date
NO904378D0 NO904378D0 (no) 1990-10-10
NO904378L NO904378L (no) 1991-10-01
NO179044B NO179044B (no) 1996-04-15
NO179044C true NO179044C (no) 1996-07-24

Family

ID=13738789

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904378A NO179044C (no) 1990-03-30 1990-10-10 Fremgangsmåte for fremstilling av et glykosaminoglykanmodifisert protein

Country Status (12)

Country Link
US (1) US5310881A (no)
EP (1) EP0454898B1 (no)
JP (1) JP2975632B2 (no)
KR (1) KR100188382B1 (no)
AT (1) ATE135375T1 (no)
AU (1) AU649416B2 (no)
CA (1) CA2027447A1 (no)
DE (1) DE69025920T2 (no)
DK (1) DK0454898T3 (no)
ES (1) ES2083989T3 (no)
FI (1) FI102836B (no)
NO (1) NO179044C (no)

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EP0502550B1 (en) * 1991-03-07 1995-01-04 Mect Corporation Colominic acid and partial hydrolysis products of colominic acid for the preparation of medicaments for the treatment of hepatitis, nephritis and arthritis
US5846951A (en) * 1991-06-06 1998-12-08 The School Of Pharmacy, University Of London Pharmaceutical compositions
GB9112212D0 (en) * 1991-06-06 1991-07-24 Gregoriadis Gregory Pharmaceutical compositions
GB2266239B (en) * 1992-03-25 1996-03-06 Jevco Ltd Wound healing compositions containing chondroitin sulphate oligosaccharides
CA2091544A1 (en) * 1992-03-26 1993-09-27 Shing F. Kwan Stabilization of functional proteins
EP0744409B9 (en) * 1994-02-23 2009-08-19 Kyowa Hakko Kogyo Co., Ltd Platelet growth accelerator
JPH09503001A (ja) * 1994-05-09 1997-03-25 ベーリンガー マンハイム ゲゼルシャフト ミット ベシュレンクテル ハフツング ニューロンを保護するためのコンドロイチン硫酸プロテオグリカンの使用
US6228998B1 (en) 1994-07-22 2001-05-08 Seikagaku Kogyo Kabushiki Kaisha Amino spacered glycosaminoglycan derivatives and their use in copolymerization with acrylamide
US5912000A (en) * 1994-09-23 1999-06-15 Zonagen, Inc. Chitosan induced immunopotentiation
WO1996009805A2 (en) * 1994-09-23 1996-04-04 Zonagen, Inc. Chitosan induced immunopotentiation
US5677276A (en) * 1994-12-23 1997-10-14 La Jolla Cancer Research Foundation Immobilization of peptides to hyaluronate
RU2176509C2 (ru) * 1995-09-19 2001-12-10 Сейкагаку Корпорейшн Средство, усиливающее противовоспалительное действие иммунодепрессанта (варианты), способ усиления противовоспалительного действия иммунодепрессанта, способ лечения воспаления
US6562781B1 (en) 1995-11-30 2003-05-13 Hamilton Civic Hospitals Research Development Inc. Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US6491965B1 (en) 1995-11-30 2002-12-10 Hamilton Civic Hospitals Research Development, Inc. Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
US7045585B2 (en) * 1995-11-30 2006-05-16 Hamilton Civic Hospital Research Development Inc. Methods of coating a device using anti-thrombin heparin
CA2266747A1 (en) * 1996-09-25 1998-04-02 Mary Ann Childs Diagnostic test devices with improved fluid movement and resistance to interferences
WO2001005434A2 (en) * 1999-07-20 2001-01-25 Amgen Inc. Hyaluronic acid-protein conjugates
EP2298354B1 (en) * 2001-10-10 2014-03-19 ratiopharm GmbH Remodelling and glycoconjugation of interferon-beta
EP2292271A3 (en) * 2001-10-10 2011-09-14 BioGeneriX AG Remodelling and glycoconjugation of an antibody
DE10209822A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
WO2004024776A1 (en) 2002-09-11 2004-03-25 Fresenius Kabi Deutschland Gmbh Method of producing hydroxyalkyl starch derivatives
US7862831B2 (en) * 2002-10-09 2011-01-04 Synthasome, Inc. Method and material for enhanced tissue-biomaterial integration
EP1558216A4 (en) * 2002-09-25 2007-01-03 Univ Johns Hopkins Med RETICULATED POLYMER MATRICES AND METHOD OF MANUFACTURING THE SAME
US8673333B2 (en) * 2002-09-25 2014-03-18 The Johns Hopkins University Cross-linked polymer matrices, and methods of making and using same
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
US7807824B2 (en) 2003-08-12 2010-10-05 Lipoxen Technologies Limited Sialic acid derivatives for protein derivatisation and conjugation
WO2006089119A2 (en) * 2005-02-18 2006-08-24 Cartilix, Inc. Biological adhesive
WO2006090119A1 (en) 2005-02-23 2006-08-31 Lipoxen Technologies Limited Activated sialic acid derivatives for protein derivatisation and conjugation
EP1886696A1 (en) * 2006-08-03 2008-02-13 Endotis Pharma Conjugates of antithrombin binding oligosaccharide derivatives and therapeutic proteins
WO2012170504A2 (en) * 2011-06-06 2012-12-13 The Cleveland Clinic Foundation Treatment of extracellular matrix to reduce inflammation
WO2015046602A1 (ja) 2013-09-30 2015-04-02 生化学工業株式会社 タンパク質の血中滞留性の増強方法

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US2824092A (en) * 1955-01-04 1958-02-18 Robert E Thompson Process of preparation of a gelatincarboxymethyl cellulose complex
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
US4301153A (en) * 1977-03-21 1981-11-17 Riker Laboratories, Inc. Heparin preparation
CA1171375A (en) * 1980-09-15 1984-07-24 Ulf P.F. Lindahl Oligosaccharides having selective anticoagulation activity
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4526714A (en) * 1982-12-13 1985-07-02 Cordis Europa N.V. Conjugates of anticoagulant and protein
NL188622C (nl) * 1981-12-15 1992-08-17 Cordis Europ Werkwijze ter verbetering van de bloedcompatibiliteit van een materiaaloppervlak door bekleding daarvan met een heparine of heparine-analoga en een eiwit houdende film, alsmede voorwerp, omvattende een oppervlak met verbeterde bloedcompatibiliteit verkregen onder toepassing van een op het oppervlak aangebrachte heparine of heparine-analoga en een eiwit houdende film.
SE8200751L (sv) * 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
US4585754A (en) * 1984-01-09 1986-04-29 Valcor Scientific, Ltd. Stabilization of proteins and peptides by chemical binding with chondroitin
US4863907A (en) * 1984-06-29 1989-09-05 Seikagaku Kogyo Co., Ltd. Crosslinked glycosaminoglycans and their use
DE3680524D1 (de) * 1986-04-22 1991-08-29 Valcor Scient Ltd Verfahren zur stabilisierung von proteinen.
US4745180A (en) * 1986-06-27 1988-05-17 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using heparin fragments
DE3636590A1 (de) * 1986-10-28 1988-05-26 Braun Melsungen Ag Blutersatzmittel
FR2631970B1 (fr) * 1988-05-24 1993-12-24 Sanofi N-polyosyl-polypeptides
DE3819079A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Hirudin-derivate mit verzoegerter wirkung
WO1990001332A1 (en) * 1988-08-10 1990-02-22 Cetus Corporation Plasminogen activator-heparin conjugates

Also Published As

Publication number Publication date
ES2083989T3 (es) 1996-05-01
FI905003A (fi) 1991-10-01
DE69025920T2 (de) 1996-08-14
ATE135375T1 (de) 1996-03-15
EP0454898A1 (en) 1991-11-06
FI102836B1 (fi) 1999-02-26
DE69025920D1 (de) 1996-04-18
NO904378D0 (no) 1990-10-10
FI102836B (fi) 1999-02-26
JPH03284698A (ja) 1991-12-16
US5310881A (en) 1994-05-10
NO179044B (no) 1996-04-15
CA2027447A1 (en) 1991-10-01
DK0454898T3 (da) 1996-04-15
KR100188382B1 (ko) 1999-06-01
KR910016770A (ko) 1991-11-05
NO904378L (no) 1991-10-01
AU6450690A (en) 1991-10-31
AU649416B2 (en) 1994-05-26
EP0454898B1 (en) 1996-03-13
FI905003A0 (fi) 1990-10-11
JP2975632B2 (ja) 1999-11-10

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