NO178371C - Ravsyreforbindelser - Google Patents
RavsyreforbindelserInfo
- Publication number
- NO178371C NO178371C NO921200A NO921200A NO178371C NO 178371 C NO178371 C NO 178371C NO 921200 A NO921200 A NO 921200A NO 921200 A NO921200 A NO 921200A NO 178371 C NO178371 C NO 178371C
- Authority
- NO
- Norway
- Prior art keywords
- group
- isomers
- carbon atoms
- atom
- lower alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/06—Preparatory processes
- C08G77/08—Preparatory processes characterised by the catalysts used
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Silicon Polymers (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3142275A JP2686861B2 (ja) | 1991-03-30 | 1991-03-30 | 新規なベンジリデンコハク酸誘導体 |
| JP3188416A JP2686863B2 (ja) | 1991-04-25 | 1991-04-25 | 新規なベンジルコハク酸誘導体 |
| JP36151991 | 1991-12-27 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO921200D0 NO921200D0 (no) | 1992-03-27 |
| NO921200L NO921200L (no) | 1992-10-01 |
| NO178371B NO178371B (no) | 1995-12-04 |
| NO178371C true NO178371C (no) | 1996-03-13 |
Family
ID=27318415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO921200A NO178371C (no) | 1991-03-30 | 1992-03-27 | Ravsyreforbindelser |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5202335A (sv) |
| EP (1) | EP0507534B1 (sv) |
| KR (1) | KR100192530B1 (sv) |
| AT (1) | ATE134615T1 (sv) |
| AU (1) | AU654331B2 (sv) |
| CA (1) | CA2062877C (sv) |
| DE (1) | DE69208496T2 (sv) |
| DK (1) | DK170973B1 (sv) |
| ES (1) | ES2084275T3 (sv) |
| FI (1) | FI102172B (sv) |
| HK (1) | HK1005449A1 (sv) |
| NO (1) | NO178371C (sv) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998032736A1 (fr) * | 1997-01-29 | 1998-07-30 | Kissei Pharmaceutical Co., Ltd. | Procede de production de derives d'acide benzylsuccinique |
| FR2765578B1 (fr) * | 1997-07-03 | 1999-09-10 | Adir | Procede de preparation d'un perhydroisoindole substitue |
| JP3277320B2 (ja) * | 1997-08-28 | 2002-04-22 | 有機合成薬品工業株式会社 | シス−ヘキサヒドロイソインドリン誘導体の製造方法 |
| FR2777566B1 (fr) * | 1998-04-15 | 2003-02-21 | Synthelabo | Derives d'azacycloalcanes, leur preparation et leur application en therapeutique |
| FR2779428B1 (fr) * | 1998-06-03 | 2001-05-18 | Synthelabo | Derives d'oxo-azacycloalcanes, leurs preparations et leurs applications en therapeutique |
| TW568788B (en) * | 1998-10-12 | 2004-01-01 | Chugai Pharmaceutical Co Ltd | Polymer combining with phosphoric acid and preparation containing the same |
| FR2793411B1 (fr) * | 1999-05-11 | 2001-06-29 | Synthelabo | Utilisation de derives de l'acide succinique pour obtenir un medicament destine au traitement de l'inflammation |
| PT1179342E (pt) * | 1999-05-21 | 2006-07-31 | Kissei Pharmaceutical | Composicoes medicinais de libertacao imediata para utilizacao oral |
| AR033390A1 (es) | 2000-08-22 | 2003-12-17 | Novartis Ag | Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes |
| KR20020092060A (ko) * | 2001-06-01 | 2002-12-11 | 김정균 | 알콕시 작용성 그룹을 포함한 폴리실록산 화합물 |
| IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
| WO2005107746A1 (ja) * | 2004-05-11 | 2005-11-17 | Kissei Pharmaceutical Co., Ltd. | 脂質代謝異常の予防または治療用医薬組成物 |
| CA2571822A1 (en) * | 2004-07-01 | 2006-01-12 | Kissei Pharmaceutical Co., Ltd. | Preventive or therapeutic agent for vascular intimal proliferative disease |
| JP2008514549A (ja) * | 2004-09-14 | 2008-05-08 | エリクシアー ファーマシューティカルズ， インコーポレイテッド | 制御された炭水化物消化のための併用療法 |
| CN1634885B (zh) * | 2004-11-09 | 2011-05-04 | 北京乐力健生物科技有限公司 | 米格列奈晶型及其制备方法 |
| CN1324010C (zh) * | 2005-01-12 | 2007-07-04 | 江苏省药物研究所 | 一种米格列奈的制备方法 |
| CN101111266A (zh) * | 2005-01-31 | 2008-01-23 | 味之素株式会社 | 含有降血糖药的用于改善或治疗糖耐量异常、临界性糖尿病、胰岛素抵抗性和高胰岛素血症的药物组合物 |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| WO2007056387A2 (en) * | 2005-11-07 | 2007-05-18 | Elixir Pharmaceuticals, Inc. | Combinations of metformin and meglitinide |
| WO2009047797A2 (en) * | 2007-10-08 | 2009-04-16 | Ind-Swift Laboratories Limited | Process for the preparation of perhydroisoindole derivative |
| US20120107239A1 (en) * | 2009-03-19 | 2012-05-03 | Nobuya Inagaki | Precursor of Molecular Probe for Pancreatic Islet Imaging and Use of the Same |
| ES2430088T3 (es) | 2009-05-15 | 2013-11-18 | Novartis Ag | Derivados de benzoxazolona como inhibidores de aldosterona sintasa |
| PE20120403A1 (es) | 2009-05-15 | 2012-05-03 | Novartis Ag | Aril-piridinas como inhibidoras de sintasa de aldosterona |
| WO2010136474A2 (en) | 2009-05-28 | 2010-12-02 | Novartis Ag | Substituted aminobutyric derivatives as neprilysin inhibitors |
| UY32662A (es) | 2009-05-28 | 2010-12-31 | Novartis Ag | Derivados amino-propionicos sustituidos como inhibidores de neprilisina |
| EP2993169B1 (en) | 2009-11-17 | 2017-12-20 | Novartis AG | Aryl-pyridine derivatives as aldosterone synthase inhibitors |
| JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| EP2507234B1 (en) | 2009-11-30 | 2014-03-12 | Novartis AG | Imidazole derivatives as aldosterone synthase inhibitors |
| CN101973926B (zh) * | 2010-11-05 | 2012-09-19 | 威海迪素制药有限公司 | R-米格列奈钙的制备方法 |
| US8673974B2 (en) | 2010-11-16 | 2014-03-18 | Novartis Ag | Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors |
| US8877815B2 (en) | 2010-11-16 | 2014-11-04 | Novartis Ag | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP |
| ES2546362B1 (es) | 2012-06-22 | 2016-07-07 | Laboratorios Lesvi, S. L. | PROCEDIMIENTO DE OBTENCIÓN DEL ÁCIDO (S) -2 BENCIL 4 - ((3aR, 7aS) -HEXAHIDRO-1H-ISOINDOL-2 (3H) IL) -4-OXOBUTANOICO Y SUS SALES |
| UY35144A (es) | 2012-11-20 | 2014-06-30 | Novartis Ag | Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca |
| US9163040B2 (en) | 2013-02-14 | 2015-10-20 | Novartis Ag | Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors |
| MX2016001020A (es) | 2013-07-25 | 2016-08-03 | Novartis Ag | Polipeptidos ciclicos para el tratamiento de insuficiencia cardiaca. |
| CA2918077A1 (en) | 2013-07-25 | 2015-01-29 | Novartis Ag | Bioconjugates of synthetic apelin polypeptides |
| BR112017014194A2 (pt) | 2015-01-23 | 2018-01-09 | Novartis Ag | conjugados de ácido graxo de apelina sintéticos com meia-vida melhorada |
| CN106631978B (zh) * | 2016-12-29 | 2020-03-24 | 千辉药业（安徽）有限责任公司 | 一种米格列奈中间体的合成工艺 |
| UY38072A (es) | 2018-02-07 | 2019-10-01 | Novartis Ag | Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4303662A (en) * | 1980-11-24 | 1981-12-01 | E. R. Squibb & Sons, Inc. | Carboxyacyl, mercapto and acylmercapto derivatives of heterobicyclo compounds |
| US4479963A (en) * | 1981-02-17 | 1984-10-30 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
| ES2061432T3 (es) * | 1985-10-09 | 1994-12-16 | Shell Int Research | Nuevas amidas de acido acrilico. |
| FR2672598A1 (fr) * | 1991-02-11 | 1992-08-14 | Adir | Nouveaux inhibiteurs de n-myristoyltransferase, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1992
- 1992-03-11 AU AU12809/92A patent/AU654331B2/en not_active Expired
- 1992-03-12 CA CA002062877A patent/CA2062877C/en not_active Expired - Lifetime
- 1992-03-27 NO NO921200A patent/NO178371C/no unknown
- 1992-03-27 DK DK041592A patent/DK170973B1/da not_active IP Right Cessation
- 1992-03-30 FI FI921392A patent/FI102172B/sv active
- 1992-03-30 KR KR1019920005274A patent/KR100192530B1/ko not_active IP Right Cessation
- 1992-03-30 EP EP92302786A patent/EP0507534B1/en not_active Expired - Lifetime
- 1992-03-30 US US07/860,023 patent/US5202335A/en not_active Expired - Lifetime
- 1992-03-30 DE DE69208496T patent/DE69208496T2/de not_active Expired - Lifetime
- 1992-03-30 ES ES92302786T patent/ES2084275T3/es not_active Expired - Lifetime
- 1992-03-30 AT AT92302786T patent/ATE134615T1/de not_active IP Right Cessation
-
1998
- 1998-05-27 HK HK98104547A patent/HK1005449A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO921200D0 (no) | 1992-03-27 |
| DK41592D0 (da) | 1992-03-27 |
| CA2062877A1 (en) | 1992-10-01 |
| EP0507534B1 (en) | 1996-02-28 |
| KR100192530B1 (ko) | 1999-06-15 |
| US5202335A (en) | 1993-04-13 |
| NO921200L (no) | 1992-10-01 |
| KR930019682A (ko) | 1993-10-18 |
| DK41592A (da) | 1992-10-01 |
| CA2062877C (en) | 2002-07-02 |
| FI921392A (fi) | 1992-10-01 |
| DE69208496T2 (de) | 1996-10-17 |
| FI102172B1 (sv) | 1998-10-30 |
| FI102172B (sv) | 1998-10-30 |
| DE69208496D1 (de) | 1996-04-04 |
| AU654331B2 (en) | 1994-11-03 |
| ATE134615T1 (de) | 1996-03-15 |
| ES2084275T3 (es) | 1996-05-01 |
| NO178371B (no) | 1995-12-04 |
| AU1280992A (en) | 1992-10-01 |
| EP0507534A1 (en) | 1992-10-07 |
| FI921392A0 (fi) | 1992-03-30 |
| DK170973B1 (da) | 1996-04-09 |
| HK1005449A1 (en) | 1999-01-08 |
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