NO177057C - Fremgangsmåte for fremstilling av pyrrolopyrimidiner og mellomprodukter derav - Google Patents

Fremgangsmåte for fremstilling av pyrrolopyrimidiner og mellomprodukter derav

Info

Publication number
NO177057C
NO177057C NO902628A NO902628A NO177057C NO 177057 C NO177057 C NO 177057C NO 902628 A NO902628 A NO 902628A NO 902628 A NO902628 A NO 902628A NO 177057 C NO177057 C NO 177057C
Authority
NO
Norway
Prior art keywords
pyrrolopyrimidines
intermediates
preparation
Prior art date
Application number
NO902628A
Other languages
English (en)
Other versions
NO902628L (no
NO177057B (no
NO902628D0 (no
Inventor
Hiroshi Akimoto
Takenori Hitaka
Tetsuo Miwa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO902628D0 publication Critical patent/NO902628D0/no
Publication of NO902628L publication Critical patent/NO902628L/no
Publication of NO177057B publication Critical patent/NO177057B/no
Publication of NO177057C publication Critical patent/NO177057C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO902628A 1989-06-14 1990-06-13 Fremgangsmåte for fremstilling av pyrrolopyrimidiner og mellomprodukter derav NO177057C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15091089 1989-06-14
JP24297589 1989-09-18
JP9239190 1990-04-06

Publications (4)

Publication Number Publication Date
NO902628D0 NO902628D0 (no) 1990-06-13
NO902628L NO902628L (no) 1990-12-17
NO177057B NO177057B (no) 1995-04-03
NO177057C true NO177057C (no) 1995-07-12

Family

ID=27307029

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902628A NO177057C (no) 1989-06-14 1990-06-13 Fremgangsmåte for fremstilling av pyrrolopyrimidiner og mellomprodukter derav

Country Status (8)

Country Link
US (2) US5349064A (no)
EP (1) EP0402903A1 (no)
JP (1) JP2983254B2 (no)
KR (1) KR0162492B1 (no)
CN (1) CN1051306C (no)
CA (1) CA2018875C (no)
HU (1) HU205358B (no)
NO (1) NO177057C (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2057635A1 (en) * 1990-12-14 1992-06-15 Hiroshi Akimoto Condensed heterocyclic compounds, their production and use
DE69216509T2 (de) * 1991-08-12 1997-05-28 Takeda Chemical Industries Ltd Kondensierte Pyrimidinderivate, ihre Herstellung und ihre Verwendung als Antitumormittel
EP0549291A1 (en) * 1991-12-27 1993-06-30 Takeda Chemical Industries, Ltd. Thymidylate synthase inhibitors
US5502187A (en) * 1992-04-03 1996-03-26 The Upjohn Company Pharmaceutically active bicyclic-heterocyclic amines
US5278307A (en) * 1992-09-25 1994-01-11 Eli Lilly And Company Process for preparing 4-hydroxypyrrolo(2,3-d)pyrimidine based antifolate compounds and intermediates
US5416211A (en) * 1992-09-25 1995-05-16 Eli Lilly And Company Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines
CZ283281B6 (cs) * 1992-09-25 1998-02-18 Eli Lilly And Company Způsob přípravy v poloze 5 substituovaných pyrrolo(2,3-d)pyrimidinů
EP0766684A4 (en) * 1994-06-09 1997-07-16 Smithkline Beecham Corp ENDOTHELINE RECEPTOR ANTAGONISTS
JP2000516961A (ja) * 1996-08-30 2000-12-19 イーライ・リリー・アンド・カンパニー 非古典的ピロロ［２，３―ｄ］ピリミジン抗葉酸物質
US7863444B2 (en) 1997-03-19 2011-01-04 Abbott Laboratories 4-aminopyrrolopyrimidines as kinase inhibitors
HUP0003954A3 (en) * 1997-09-26 2002-12-28 Lilly Co Eli Processes and intermediates useful to prepare pyrrolo [2,3-d] pyrimidine derivatives
PA8474101A1 (es) * 1998-06-19 2000-09-29 Pfizer Prod Inc Compuestos de pirrolo [2,3-d] pirimidina
ES2253930T3 (es) * 1998-09-18 2006-06-01 ABBOTT GMBH & CO. KG 4-aminopirrolopirimidinas como inhibidores de quinasa.
US6713474B2 (en) 1998-09-18 2004-03-30 Abbott Gmbh & Co. Kg Pyrrolopyrimidines as therapeutic agents
US7071199B1 (en) 1999-09-17 2006-07-04 Abbott Gmbh & Cco. Kg Kinase inhibitors as therapeutic agents
ATE247657T1 (de) 1999-09-17 2003-09-15 Basf Ag Pyrazolopyrimidine als arzneimittel
SK287188B6 (sk) 1999-12-10 2010-02-08 Pfizer Products Inc. Pyrolo [2,3-d]pyrimidínová zlúčenina, jej použitie a farmaceutická kompozícia alebo kombinácia s jej obsahom
CN1717236A (zh) * 2002-11-26 2006-01-04 辉瑞产品公司 治疗移植排斥的方法
DE112008001428T5 (de) * 2007-05-21 2010-04-29 Bol, Stephen J., Muskegon Radfeste Pumpe für sich selbst aufblasende Reifen
DK2384326T3 (da) 2008-08-20 2014-05-05 Zoetis Llc Pyrrolo[2,3-d]pyrimidinforbindelser
US8385364B2 (en) * 2008-09-24 2013-02-26 Nec Laboratories America, Inc. Distributed message-passing based resource allocation in wireless systems

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB812366A (en) * 1955-08-18 1959-04-22 Wellcome Found Improvements in and relating to derivatives of pyrimidine and the preparation thereof
GB8625019D0 (en) * 1986-10-18 1986-11-19 Wellcome Found Compounds
US4871743A (en) * 1988-01-19 1989-10-03 The Trustees Of Princeton University L-glutamic acid derivatives
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
NO169490C (no) * 1988-03-24 1992-07-01 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolopyrimidinderivater

Also Published As

Publication number Publication date
CN1051306C (zh) 2000-04-12
NO902628L (no) 1990-12-17
US5496946A (en) 1996-03-05
KR910000736A (ko) 1991-01-30
CA2018875C (en) 2000-10-31
US5349064A (en) 1994-09-20
HU903853D0 (en) 1990-11-28
EP0402903A1 (en) 1990-12-19
CN1103401A (zh) 1995-06-07
NO177057B (no) 1995-04-03
JPH049383A (ja) 1992-01-14
NO902628D0 (no) 1990-06-13
KR0162492B1 (ko) 1998-12-01
CA2018875A1 (en) 1990-12-14
JP2983254B2 (ja) 1999-11-29
HU205358B (en) 1992-04-28

Similar Documents

Publication Publication Date Title
NO177057C (no) Fremgangsmåte for fremstilling av pyrrolopyrimidiner og mellomprodukter derav
PT86875A (pt) Process for the preparation of phenylcarbamate
NO176922C (no) Fremgangsmåte for fremstilling av bifunksjonelle proteiner
IT1219369B (it) Specchio decorativo e procedimento per la sua fabbricazione
IL92681A0 (en) Process and intermediates for the preparation of 4-phenylpiperidines
FI91961C (fi) Menetelmä (S)- -etyyli-2-okso-1-pyrrolidiiniasetamidin valmistamiseksi
IT8947842A0 (it) Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
KR900009566A (ko) 말레이미드류의 제조법
PL289382A1 (en) Method of obtaining novel phosphonomethylothioethoxypurines
NO307740B1 (no) Fremgangsmõte for fremstilling av katalysatorer og anvendelse av denne
NO881713D0 (no) Fremgangsmaate for fremstilling av di-t-butylfenyl-alkyl og benzylethere.
DK0388620T3 (da) Fremgangsmåde til fremstilling af o-carboxy-pyridyl- og o-carboxyquinolylimidazolinoner
NO307080B1 (no) Fremgangsmåte for fremstilling av katalysatorer og anvendelse derav
NO905543D0 (no) Fremgangsmaate for fremstilling og anvendelse av aminopyridinylmetanoler og aminometylpyridinaminer.
KR900015532U (ko) 일부인
FI901358A0 (fi) Menetelmä fluorifenolien valmistamiseksi
PT87732A (pt) Process for the preparation of (e)-(p-fluorophenethyl)-3-fluoroallylamine
FI93363C (fi) Uusi menetelmä 2-diatso-3-trisubstituoitujen silyylioksi-3-butenoaattien valmistamiseksi
EP0440078A3 (en) Process for the preparation of retinylglycosides and intermediates for this process
NO921168L (no) Fremgangsmaate og anordning for fremstilling av elementaertjod i ren form
EP0398097A3 (en) Process and intermediates for the preparation of triazolone derivatives
EP0427942A3 (en) Process for the preparation of s-triazine-sulfenimides and their use
FR2646799B1 (fr) Procede de fabrication et decoration de ceramiques
FR2599038B1 (fr) Procede de preparation de nonacosapeptides et peptides intermediaires
IL103656A0 (en) Intermediates for the preparation of 1-benzoyl-3-trifluoromethylurea derivatives and process for their preparation

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN DECEMBER 2001