NO175899C - Analogifremgangsmåte for fremstilling av terapeutisk aktive heksahydropyrrolo(2,3-b)indol karbamater-, urea-, -amider og beslektede forbindelser - Google Patents
Analogifremgangsmåte for fremstilling av terapeutisk aktive heksahydropyrrolo(2,3-b)indol karbamater-, urea-, -amider og beslektede forbindelserInfo
- Publication number
- NO175899C NO175899C NO910372A NO910372A NO175899C NO 175899 C NO175899 C NO 175899C NO 910372 A NO910372 A NO 910372A NO 910372 A NO910372 A NO 910372A NO 175899 C NO175899 C NO 175899C
- Authority
- NO
- Norway
- Prior art keywords
- hexahydropyrrolo
- amides
- urea
- preparation
- therapeutically active
- Prior art date
Links
- FGIMGRQUFHEOSG-UHFFFAOYSA-N 1,2,4,8,8a,8b-hexahydropyrrolo[2,3-b]indole;carbamic acid Chemical compound NC(O)=O.C12CC=CC=C2N=C2C1CCN2 FGIMGRQUFHEOSG-UHFFFAOYSA-N 0.000 title 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 150000001408 amides Chemical class 0.000 title 1
- 239000004202 carbamide Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/480,706 US4983616A (en) | 1990-02-01 | 1990-02-01 | Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO910372D0 NO910372D0 (no) | 1991-01-31 |
| NO910372L NO910372L (no) | 1991-08-02 |
| NO175899B NO175899B (no) | 1994-09-19 |
| NO175899C true NO175899C (no) | 1994-12-28 |
Family
ID=23909022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO910372A NO175899C (no) | 1990-02-01 | 1991-01-31 | Analogifremgangsmåte for fremstilling av terapeutisk aktive heksahydropyrrolo(2,3-b)indol karbamater-, urea-, -amider og beslektede forbindelser |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4983616A (cs) |
| EP (1) | EP0440145A1 (cs) |
| JP (1) | JP3042902B2 (cs) |
| KR (1) | KR0182296B1 (cs) |
| AU (1) | AU629094B2 (cs) |
| CA (1) | CA2035397C (cs) |
| CZ (1) | CZ281612B6 (cs) |
| FI (1) | FI94759C (cs) |
| HU (1) | HU217119B (cs) |
| IE (1) | IE910333A1 (cs) |
| IL (1) | IL97113A (cs) |
| NO (1) | NO175899C (cs) |
| NZ (1) | NZ236944A (cs) |
| PL (1) | PL288904A1 (cs) |
| PT (1) | PT96627A (cs) |
| TW (1) | TW206228B (cs) |
| ZA (1) | ZA91725B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| US5187165A (en) * | 1987-05-15 | 1993-02-16 | Hoechst-Roussel Pharmaceuticals Inc. | Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles |
| AU634654B2 (en) * | 1990-05-11 | 1993-02-25 | Hoechst-Roussel Pharmaceuticals Incorporated | Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments |
| US5665880A (en) * | 1996-10-31 | 1997-09-09 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseretholes |
| US5677457A (en) * | 1996-12-19 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of preparation of physostigmine carbamate derivatives from eseroline ethers |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2934657A1 (de) * | 1979-08-28 | 1981-03-12 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von thiochlorformiaten. |
| IT1199076B (it) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione |
| US4680172A (en) * | 1985-03-05 | 1987-07-14 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| IT1225462B (it) * | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
| US4971992A (en) * | 1989-03-27 | 1990-11-20 | Hoechst-Roussel Pharmaceuticals Inc. | Carbonate derivatives of eseroline |
| AU634654B2 (en) * | 1990-05-11 | 1993-02-25 | Hoechst-Roussel Pharmaceuticals Incorporated | Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments |
| AU634380B2 (en) * | 1990-05-17 | 1993-02-18 | Hoechst-Roussel Pharmaceuticals Incorporated | Alpha-oxopyrrolo(2,3-b)indole acetic acids, esters, amides and related analogs, a process for their preparation and their use as medicaments |
-
1990
- 1990-02-01 US US07/480,706 patent/US4983616A/en not_active Expired - Fee Related
-
1991
- 1991-01-28 EP EP91101093A patent/EP0440145A1/en not_active Withdrawn
- 1991-01-30 FI FI910448A patent/FI94759C/fi active
- 1991-01-30 CZ CS91215A patent/CZ281612B6/cs not_active IP Right Cessation
- 1991-01-30 NZ NZ236944A patent/NZ236944A/xx unknown
- 1991-01-30 HU HU91325A patent/HU217119B/hu not_active IP Right Cessation
- 1991-01-31 PT PT96627A patent/PT96627A/pt not_active Application Discontinuation
- 1991-01-31 JP JP3029121A patent/JP3042902B2/ja not_active Expired - Lifetime
- 1991-01-31 AU AU70111/91A patent/AU629094B2/en not_active Ceased
- 1991-01-31 CA CA002035397A patent/CA2035397C/en not_active Expired - Fee Related
- 1991-01-31 KR KR1019910001611A patent/KR0182296B1/ko not_active Expired - Fee Related
- 1991-01-31 ZA ZA91725A patent/ZA91725B/xx unknown
- 1991-01-31 PL PL28890491A patent/PL288904A1/xx unknown
- 1991-01-31 IE IE033391A patent/IE910333A1/en unknown
- 1991-01-31 IL IL9711391A patent/IL97113A/en not_active IP Right Cessation
- 1991-01-31 NO NO910372A patent/NO175899C/no unknown
- 1991-02-12 TW TW080101108A patent/TW206228B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| PL288904A1 (en) | 1992-08-10 |
| KR910021401A (ko) | 1991-12-20 |
| JP3042902B2 (ja) | 2000-05-22 |
| CZ281612B6 (cs) | 1996-11-13 |
| CA2035397C (en) | 2001-10-23 |
| HUT60499A (en) | 1992-09-28 |
| IE910333A1 (en) | 1991-08-14 |
| PT96627A (pt) | 1991-10-15 |
| FI94759C (fi) | 1995-10-25 |
| US4983616A (en) | 1991-01-08 |
| NZ236944A (en) | 1993-02-25 |
| AU7011191A (en) | 1991-08-08 |
| IL97113A (en) | 1994-10-21 |
| KR0182296B1 (ko) | 1999-05-01 |
| CA2035397A1 (en) | 1991-08-02 |
| JPH04330076A (ja) | 1992-11-18 |
| HU217119B (hu) | 1999-11-29 |
| FI94759B (fi) | 1995-07-14 |
| FI910448A7 (fi) | 1991-08-02 |
| HU910325D0 (en) | 1991-08-28 |
| NO175899B (no) | 1994-09-19 |
| TW206228B (cs) | 1993-05-21 |
| NO910372D0 (no) | 1991-01-31 |
| EP0440145A1 (en) | 1991-08-07 |
| FI910448A0 (fi) | 1991-01-30 |
| NO910372L (no) | 1991-08-02 |
| IL97113A0 (en) | 1992-03-29 |
| CS9100215A2 (en) | 1991-09-15 |
| ZA91725B (en) | 1991-11-27 |
| AU629094B2 (en) | 1992-09-24 |
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