IL97113A - Hexahydropyrrolo [2,3-b] indole carbamates, ureas, and -amides, a process for their preparation and their use as medicaments - Google Patents

Hexahydropyrrolo [2,3-b] indole carbamates, ureas, and -amides, a process for their preparation and their use as medicaments

Info

Publication number
IL97113A
IL97113A IL9711391A IL9711391A IL97113A IL 97113 A IL97113 A IL 97113A IL 9711391 A IL9711391 A IL 9711391A IL 9711391 A IL9711391 A IL 9711391A IL 97113 A IL97113 A IL 97113A
Authority
IL
Israel
Prior art keywords
compound
formula
hydrogen
defined above
loweralkyl
Prior art date
Application number
IL9711391A
Other languages
English (en)
Other versions
IL97113A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL97113A0 publication Critical patent/IL97113A0/xx
Publication of IL97113A publication Critical patent/IL97113A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9711391A 1990-02-01 1991-01-31 Hexahydropyrrolo [2,3-b] indole carbamates, ureas, and -amides, a process for their preparation and their use as medicaments IL97113A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/480,706 US4983616A (en) 1990-02-01 1990-02-01 Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds

Publications (2)

Publication Number Publication Date
IL97113A0 IL97113A0 (en) 1992-03-29
IL97113A true IL97113A (en) 1994-10-21

Family

ID=23909022

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9711391A IL97113A (en) 1990-02-01 1991-01-31 Hexahydropyrrolo [2,3-b] indole carbamates, ureas, and -amides, a process for their preparation and their use as medicaments

Country Status (17)

Country Link
US (1) US4983616A (cs)
EP (1) EP0440145A1 (cs)
JP (1) JP3042902B2 (cs)
KR (1) KR0182296B1 (cs)
AU (1) AU629094B2 (cs)
CA (1) CA2035397C (cs)
CZ (1) CZ281612B6 (cs)
FI (1) FI94759C (cs)
HU (1) HU217119B (cs)
IE (1) IE910333A1 (cs)
IL (1) IL97113A (cs)
NO (1) NO175899C (cs)
NZ (1) NZ236944A (cs)
PL (1) PL288904A1 (cs)
PT (1) PT96627A (cs)
TW (1) TW206228B (cs)
ZA (1) ZA91725B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US5187165A (en) * 1987-05-15 1993-02-16 Hoechst-Roussel Pharmaceuticals Inc. Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2934657A1 (de) * 1979-08-28 1981-03-12 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von thiochlorformiaten.
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
AU634380B2 (en) * 1990-05-17 1993-02-18 Hoechst-Roussel Pharmaceuticals Incorporated Alpha-oxopyrrolo(2,3-b)indole acetic acids, esters, amides and related analogs, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
PL288904A1 (en) 1992-08-10
KR910021401A (ko) 1991-12-20
JP3042902B2 (ja) 2000-05-22
CZ281612B6 (cs) 1996-11-13
CA2035397C (en) 2001-10-23
HUT60499A (en) 1992-09-28
IE910333A1 (en) 1991-08-14
PT96627A (pt) 1991-10-15
FI94759C (fi) 1995-10-25
US4983616A (en) 1991-01-08
NZ236944A (en) 1993-02-25
AU7011191A (en) 1991-08-08
NO175899C (no) 1994-12-28
KR0182296B1 (ko) 1999-05-01
CA2035397A1 (en) 1991-08-02
JPH04330076A (ja) 1992-11-18
HU217119B (hu) 1999-11-29
FI94759B (fi) 1995-07-14
FI910448A7 (fi) 1991-08-02
HU910325D0 (en) 1991-08-28
NO175899B (no) 1994-09-19
TW206228B (cs) 1993-05-21
NO910372D0 (no) 1991-01-31
EP0440145A1 (en) 1991-08-07
FI910448A0 (fi) 1991-01-30
NO910372L (no) 1991-08-02
IL97113A0 (en) 1992-03-29
CS9100215A2 (en) 1991-09-15
ZA91725B (en) 1991-11-27
AU629094B2 (en) 1992-09-24

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Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
MM9K Patent not in force due to non-payment of renewal fees