NO174816B - Fremgangsmåte for fremstilling av human-lysozym, rekombinant DNA-molekyl, ekspresjonsvektorer, samt transformert gjærcelle - Google Patents

Fremgangsmåte for fremstilling av human-lysozym, rekombinant DNA-molekyl, ekspresjonsvektorer, samt transformert gjærcelle Download PDF

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Publication number
NO174816B
NO174816B NO864495A NO864495A NO174816B NO 174816 B NO174816 B NO 174816B NO 864495 A NO864495 A NO 864495A NO 864495 A NO864495 A NO 864495A NO 174816 B NO174816 B NO 174816B
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NO
Norway
Prior art keywords
hlz
gene
sequence
dna
factor
Prior art date
Application number
NO864495A
Other languages
English (en)
Norwegian (no)
Other versions
NO864495D0 (no
NO864495L (no
NO174816C (da
Inventor
Andrzej Sledziewski
Ewa Sledziewska Chlebowicz
Peter Swetly
Gunther Adolf
Rudolf Hauptmann
Maria Josefa Castanon
Walter Spevak
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO864495D0 publication Critical patent/NO864495D0/no
Publication of NO864495L publication Critical patent/NO864495L/no
Publication of NO174816B publication Critical patent/NO174816B/no
Publication of NO174816C publication Critical patent/NO174816C/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462Lysozyme (3.2.1.17)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO864495A 1985-11-12 1986-11-11 Fremgangsmåte for fremstilling av human-lysozym, rekombinant DNA-molekyl, ekspresjonsvektorer, samt transformert gjærcelle NO174816B (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853540075 DE3540075A1 (de) 1985-11-12 1985-11-12 Human-lysozym

Publications (4)

Publication Number Publication Date
NO864495D0 NO864495D0 (no) 1986-11-11
NO864495L NO864495L (no) 1987-05-13
NO174816B true NO174816B (no) 1994-04-05
NO174816C NO174816C (da) 1994-07-13

Family

ID=6285752

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864495A NO174816B (no) 1985-11-12 1986-11-11 Fremgangsmåte for fremstilling av human-lysozym, rekombinant DNA-molekyl, ekspresjonsvektorer, samt transformert gjærcelle

Country Status (18)

Country Link
US (1) US5618712A (da)
EP (1) EP0222366B1 (da)
JP (1) JPS62163692A (da)
KR (1) KR940005583B1 (da)
AT (1) ATE71658T1 (da)
AU (1) AU601164B2 (da)
DE (2) DE3540075A1 (da)
DK (1) DK538286A (da)
ES (1) ES2040202T3 (da)
FI (1) FI88407C (da)
GR (1) GR3003691T3 (da)
HU (1) HU202923B (da)
IE (1) IE59428B1 (da)
IL (1) IL80562A0 (da)
NO (1) NO174816B (da)
NZ (1) NZ218247A (da)
PT (1) PT83719B (da)
ZA (1) ZA868540B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6447377A (en) * 1987-08-19 1989-02-21 Agency Ind Science Techn Mutant strain having high secretion of human lysozyme, its selection and production of human lysozyme using same
US20030166188A1 (en) 1997-09-18 2003-09-04 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20050196832A1 (en) * 1997-09-18 2005-09-08 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030166132A1 (en) 1998-08-26 2003-09-04 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1111060A4 (en) * 1998-08-31 2003-01-02 Long Yu HUMAN LYSOZYME GENE, CODED POLYPEPTIDE AND METHOD FOR THE PRODUCTION THEREOF
US6660512B1 (en) * 1998-08-31 2003-12-09 Long Yu Human lysozyme gene, it's encoded polypeptide and the method of preparing them
AU5502199A (en) * 1998-08-31 2000-03-21 Long Yu A novel human lysozyme gene, its encoding polypeptide and the method for preparing them
CA2349837A1 (en) * 1998-11-18 2000-05-25 Children's Hospital Medical Center Lysozyme fusion proteins in infections
WO2001066802A1 (en) * 2000-03-09 2001-09-13 Genetag Technology, Inc. SYSTEMS AND METHODS TO QUANTIFY AND AMPLIFY BOTH SIGNALING AND PROBES FOR cDNA CHIPS AND GENES EXPRESSION MICROARRAYS
US7138150B2 (en) * 2000-05-02 2006-11-21 Ventria Bioscience Method of making an anti-infective composition for treating oral infections
US7417178B2 (en) * 2000-05-02 2008-08-26 Ventria Bioscience Expression of human milk proteins in transgenic plants
US20080050503A1 (en) * 2000-05-02 2008-02-28 Ning Huang Expression of human milk proteins in transgenic plants
CN1205917C (zh) * 2002-06-05 2005-06-15 长春奇龙生物技术研究所 一种人溶菌酶系列化妆品及其制备方法
WO2006028497A2 (en) * 2004-02-20 2006-03-16 University Of Virginia Patent Foundation Active recombinant human lysozyme
CN1583170A (zh) * 2004-06-10 2005-02-23 安米 用于抗病毒抗耐药菌的人溶菌酶药物及其制法
US20060286086A1 (en) * 2005-06-21 2006-12-21 Saint Simeon Lda Lysozyme-based food stuff
CN115232207B (zh) * 2022-05-19 2023-06-13 河南大学 抗体-溶菌素(SM-ScFv-Fc-Ly)在治疗变形链球菌感染中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546082A (en) * 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
US4523330A (en) * 1982-12-23 1985-06-11 Ncr Canada Ltd - Ncr Canada Ltee Banking system and method
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
JPS59227899A (ja) * 1983-05-25 1984-12-21 チロン・コ−ポレイシヨン 成長ホルモン放出因子の製造方法
US4757006A (en) * 1983-10-28 1988-07-12 Genetics Institute, Inc. Human factor VIII:C gene and recombinant methods for production
EP0155189A3 (en) * 1984-03-16 1987-09-16 Genentech, Inc. Expression of cell wall degrading proteins and host cells harboring dna encoding such protein
US4766068A (en) * 1984-06-16 1988-08-23 Agency Of Industrial Science And Technology Cytochrome P-450MC gene, expression plasmid carrying the said gene, yeasts transformed with the said plasmid and a process for producing cytochrome P-450MC by culturing the said transformant yeasts
JPS6178383A (ja) * 1984-09-26 1986-04-21 Agency Of Ind Science & Technol ヒトリゾチ−ムの微生物学的製造法
JPS61158793A (ja) * 1984-11-14 1986-07-18 Takeda Chem Ind Ltd ヒト・リゾチ−ムの合成遺伝子
BE901223A (fr) * 1984-12-06 1985-03-29 Labofina Sa Levures transformees produisant du lysozyme plasmides utilises pour cette transformation et leurs utilisations.
JPS626679A (ja) * 1985-06-26 1987-01-13 Agency Of Ind Science & Technol ヒトリゾチ−ムの微生物学的製造法
TW205070B (da) * 1986-06-30 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
KR940005583B1 (ko) 1994-06-21
AU6502986A (en) 1987-05-14
KR870005091A (ko) 1987-06-04
NZ218247A (en) 1991-08-27
DK538286A (da) 1987-05-13
FI88407B (fi) 1993-01-29
NO864495D0 (no) 1986-11-11
US5618712A (en) 1997-04-08
FI88407C (fi) 1993-05-10
IE862975L (en) 1987-05-12
GR3003691T3 (da) 1993-03-16
ZA868540B (en) 1988-07-27
PT83719B (pt) 1989-06-30
IL80562A0 (en) 1987-02-27
AU601164B2 (en) 1990-09-06
IE59428B1 (en) 1994-02-23
EP0222366A3 (en) 1987-09-30
ES2040202T3 (es) 1993-10-16
HUT43111A (en) 1987-09-28
DE3683447D1 (de) 1992-02-27
NO864495L (no) 1987-05-13
EP0222366B1 (de) 1992-01-15
FI864552A (fi) 1987-05-13
DE3540075A1 (de) 1987-05-14
HU202923B (en) 1991-04-29
PT83719A (en) 1986-12-01
FI864552A0 (fi) 1986-11-10
ATE71658T1 (de) 1992-02-15
EP0222366A2 (de) 1987-05-20
NO174816C (da) 1994-07-13
DK538286D0 (da) 1986-11-11
JPS62163692A (ja) 1987-07-20

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