NO171631C - Fremgangsmaate for fremstilling av deuterert benzaldehyd og derivater derav - Google Patents

Fremgangsmaate for fremstilling av deuterert benzaldehyd og derivater derav

Info

Publication number
NO171631C
NO171631C NO880964A NO880964A NO171631C NO 171631 C NO171631 C NO 171631C NO 880964 A NO880964 A NO 880964A NO 880964 A NO880964 A NO 880964A NO 171631 C NO171631 C NO 171631C
Authority
NO
Norway
Prior art keywords
derivatives
deututed
benzaldehyde
procedure
preparation
Prior art date
Application number
NO880964A
Other languages
English (en)
Norwegian (no)
Other versions
NO880964L (no
NO171631B (no
NO880964D0 (no
Inventor
Bernt Boerretzen
Rolf Olav Larsen
John Michael Dornish
Reidar Oftebro
Erik Olai Pettersen
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Publication of NO880964D0 publication Critical patent/NO880964D0/no
Publication of NO880964L publication Critical patent/NO880964L/no
Priority to NO921423A priority Critical patent/NO172042C/no
Publication of NO171631B publication Critical patent/NO171631B/no
Publication of NO171631C publication Critical patent/NO171631C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/39—Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Plant Substances (AREA)
NO880964A 1987-03-11 1988-03-04 Fremgangsmaate for fremstilling av deuterert benzaldehyd og derivater derav NO171631C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO921423A NO172042C (no) 1987-03-11 1992-04-10 Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878705780A GB8705780D0 (en) 1987-03-11 1987-03-11 Anticancer compounds

Publications (4)

Publication Number Publication Date
NO880964D0 NO880964D0 (no) 1988-03-04
NO880964L NO880964L (no) 1988-09-12
NO171631B NO171631B (no) 1993-01-04
NO171631C true NO171631C (no) 1993-04-14

Family

ID=10613770

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880964A NO171631C (no) 1987-03-11 1988-03-04 Fremgangsmaate for fremstilling av deuterert benzaldehyd og derivater derav

Country Status (12)

Country Link
US (1) US4874780A (de)
EP (1) EP0283139B1 (de)
JP (1) JP2769492B2 (de)
AT (1) ATE84515T1 (de)
AU (1) AU612348B2 (de)
CA (1) CA1327038C (de)
DE (1) DE3877386T2 (de)
DK (1) DK173244B1 (de)
ES (1) ES2043807T3 (de)
GB (1) GB8705780D0 (de)
HK (1) HK68697A (de)
NO (1) NO171631C (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032610A (en) * 1988-11-21 1991-07-16 Norsk Hydro As Activity against carcinoma and method for the treatment of carcinoma
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
GB9026080D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As Pharmaceutical compositions
HU208084B (en) * 1991-10-31 1993-08-30 Hyd Kutato Fejlesztoe Kft Process for producing compositions suitable for curing tumorous diseases
GB9201274D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
GB9201275D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
GB9400047D0 (en) * 1994-01-04 1994-03-02 Norsk Hydro As Pharmaceutical compositions
KR100477070B1 (ko) * 1994-03-25 2006-04-21 이소테크니카 인코포레이티드 중수소화작용에의한의약품의효능강화법
US6334997B1 (en) * 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
DE4417865A1 (de) * 1994-05-20 1995-11-23 Behringwerke Ag Kombination von Tumornekrose-induzierenden Substanzen mit Substanzen, die durch Nekrosen aktiviert werden, zur selektiven Tumortherapie
DE4427690A1 (de) * 1994-08-04 1996-02-08 Bogdahn Ulrich Prof Deuterium enthaltende pharmazeutische Zusammensetzung als Zytostatikum oder Tumor-Therapeutikum
NO309305B1 (no) * 1999-02-19 2001-01-15 Norsk Hydro As Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater
CN105101792A (zh) * 2013-03-15 2015-11-25 杜特里亚农用化学品有限责任公司 氘富集醛类
US9713330B1 (en) 2013-03-15 2017-07-25 Deuteria Agrochemicals, Llc Deuterium-enriched aldehydes
KR20200119246A (ko) * 2018-01-12 2020-10-19 이엔비 테라퓨틱스, 인크. Etbr 활성화와 관련된 암을 치료하기 위한 중수소화 화합물, 조성물, 및 방법
CN108383697B (zh) * 2018-02-12 2021-11-19 中山大学 一种以卤甲基化合物为原料制备氘代醛的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52108027A (en) * 1976-03-09 1977-09-10 Rikagaku Kenkyusho Anticarcinogen
GB1582666A (en) * 1976-08-24 1981-01-14 Rikagaku Kenkyusho Treatment of malignant conditions with mandelic acid or derivatives thereof
US4146651A (en) * 1977-05-20 1979-03-27 Canada Packers Limited Acetals and ketals of ascorbic acid and anti-nitrosamine compositions and methods using same
US4297289A (en) * 1980-07-17 1981-10-27 Wisconsin Alumni Research Foundation Vitamin D compounds isotopically substituted at carbon 6 and process for their preparation
US4423236A (en) * 1980-08-14 1983-12-27 National Foundation For Cancer Research, Inc. 5,6,-0-Isoalkylidene ascorbic acid derivatives
JPS60139619A (ja) * 1983-12-27 1985-07-24 Mutsuyuki Kochi Ｏ−ベンジリデン−アスコルビン酸又はその塩よりなる抗腫瘍剤

Also Published As

Publication number Publication date
NO880964L (no) 1988-09-12
ES2043807T3 (es) 1994-01-01
DE3877386T2 (de) 1993-08-12
DK129788A (da) 1988-09-12
EP0283139A2 (de) 1988-09-21
NO171631B (no) 1993-01-04
CA1327038C (en) 1994-02-15
GB8705780D0 (en) 1987-04-15
HK68697A (en) 1997-05-30
DK129788D0 (da) 1988-03-10
EP0283139A3 (en) 1989-01-18
DE3877386D1 (de) 1993-02-25
NO880964D0 (no) 1988-03-04
ATE84515T1 (de) 1993-01-15
EP0283139B1 (de) 1993-01-13
JPS63250341A (ja) 1988-10-18
AU1233188A (en) 1988-09-15
JP2769492B2 (ja) 1998-06-25
DK173244B1 (da) 2000-05-22
US4874780A (en) 1989-10-17
AU612348B2 (en) 1991-07-11

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