NO170482C - Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksamid-derivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksamid-derivater

Info

Publication number
NO170482C
NO170482C NO864130A NO864130A NO170482C NO 170482 C NO170482 C NO 170482C NO 864130 A NO864130 A NO 864130A NO 864130 A NO864130 A NO 864130A NO 170482 C NO170482 C NO 170482C
Authority
NO
Norway
Prior art keywords
preparation
carboxamide derivatives
therapeutic active
analogy procedure
active carboxamide
Prior art date
Application number
NO864130A
Other languages
English (en)
Other versions
NO864130L (no
NO170482B (no
NO864130D0 (no
Inventor
Peter Robert Bernstein
Frederick Jeffrey Brown
Victor Guilio Matassa
Ying Kwong Yee
Original Assignee
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858525658A external-priority patent/GB8525658D0/en
Priority claimed from GB868609176A external-priority patent/GB8609176D0/en
Application filed by Ici America Inc filed Critical Ici America Inc
Publication of NO864130D0 publication Critical patent/NO864130D0/no
Publication of NO864130L publication Critical patent/NO864130L/no
Publication of NO170482B publication Critical patent/NO170482B/no
Publication of NO170482C publication Critical patent/NO170482C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
NO864130A 1985-10-17 1986-10-16 Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksamid-derivater NO170482C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858525658A GB8525658D0 (en) 1985-10-17 1985-10-17 Heterocyclic amide derivatives
GB868609176A GB8609176D0 (en) 1986-04-15 1986-04-15 Carboxamide derivatives

Publications (4)

Publication Number Publication Date
NO864130D0 NO864130D0 (no) 1986-10-16
NO864130L NO864130L (no) 1987-04-21
NO170482B NO170482B (no) 1992-07-13
NO170482C true NO170482C (no) 1992-10-21

Family

ID=26289900

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864130A NO170482C (no) 1985-10-17 1986-10-16 Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksamid-derivater

Country Status (19)

Country Link
US (3) US4918094A (no)
EP (1) EP0220066B1 (no)
JP (1) JP2512724B2 (no)
KR (1) KR900004385B1 (no)
AU (1) AU595839B2 (no)
CA (1) CA1336192C (no)
DE (1) DE3684549D1 (no)
DK (1) DK169964B1 (no)
ES (1) ES2032384T3 (no)
FI (1) FI83866C (no)
GB (1) GB8623429D0 (no)
GR (1) GR3004137T3 (no)
HK (1) HK18197A (no)
HU (1) HU197724B (no)
IE (1) IE60480B1 (no)
IL (1) IL80335A (no)
NO (1) NO170482C (no)
NZ (1) NZ217962A (no)
PT (1) PT83558B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3650567T2 (de) * 1985-10-17 1997-02-20 Zeneca Inc Medizinische Indol- und Indazol-Ketosulfonderivate
US5041460A (en) * 1988-04-14 1991-08-20 Ici Americas Inc. Heter-aliphatic carboxamides
US5286740A (en) * 1989-12-11 1994-02-15 Imperial Chemical Industries Plc Carbamoyl derivatives
GB8927981D0 (en) * 1989-12-11 1990-02-14 Ici Plc Carbamoyl derivative
DK0455596T3 (da) * 1990-05-04 1994-11-28 Ciba Geigy Ag Substituerede indoler
US5095031A (en) * 1990-08-20 1992-03-10 Abbott Laboratories Indole derivatives which inhibit leukotriene biosynthesis
GB9026427D0 (en) * 1990-12-05 1991-01-23 Ici Plc Chemical process
EP0511477B1 (en) * 1991-03-11 1996-07-10 Kyowa Hakko Kogyo Co., Ltd. Indole derivatives
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
ES2072125T3 (es) * 1991-10-25 1995-07-01 Ciba Geigy Ag Procedimiento para la obtencion de indoles substituidos.
EP0539329A1 (de) * 1991-10-25 1993-04-28 Ciba-Geigy Ag Acetylen-Verbindungen, verwendbar als Leukotrien-Antagonisten
ES2050611B1 (es) * 1992-10-08 1994-12-16 Ici Plc Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
US5288743A (en) * 1992-11-20 1994-02-22 Abbott Laboratories Indole carboxylate derivatives which inhibit leukotriene biosynthesis
WO2001007031A1 (fr) * 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Derives de benzene, compositions immunostimulantes ou agents de retablissement de la pharmacosensibilite les contenant
US6614627B1 (en) * 2000-02-14 2003-09-02 Hitachi, Ltd. Magnetic disk apparatus
WO2010111060A1 (en) * 2009-03-23 2010-09-30 Merck Sharp & Dohme Corp. P2x3, receptor antagonists for treatment of pain
JP2020111510A (ja) * 2017-03-29 2020-07-27 科研製薬株式会社 インダゾール誘導体及びそれを含有する医薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271416A (en) * 1961-10-24 1966-09-06 Merck & Co Inc Indolyl aliphatic acids
FR4035M (no) * 1964-11-04 1966-03-28
FR7631M (no) * 1968-08-13 1970-01-26
US3470298A (en) * 1969-01-29 1969-09-30 Acraf Topical anti-inflammatory composition containing (indazole-3-yl)-oxyalkanoic acids
BE738727A (en) * 1969-09-11 1970-02-16 Anti inflammatory analgesic and antipyretic indolyalkanoic - acids and derivs
DE2854987A1 (de) * 1978-12-20 1980-06-26 Boehringer Mannheim Gmbh Diagnostische mittel zum nachweis proteolytischer enzyme und dafuer geeignete chromogene
US4499299A (en) * 1981-12-30 1985-02-12 Ici Americas Inc. Pharmaceutically active phenylcarboxylic acid derivatives
CA1241660A (en) * 1984-06-25 1988-09-06 Yvan Guindon Indole-2-alkanoic acids
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
GB8426474D0 (en) * 1984-10-19 1984-11-28 Ici America Inc Heterocyclic amides
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives

Also Published As

Publication number Publication date
JP2512724B2 (ja) 1996-07-03
DK169964B1 (da) 1995-04-18
US5049679A (en) 1991-09-17
ES2032384T3 (es) 1993-02-16
PT83558B (pt) 1989-05-31
IE862738L (en) 1987-04-17
NO864130L (no) 1987-04-21
AU595839B2 (en) 1990-04-12
FI864191A (fi) 1987-04-18
GR3004137T3 (no) 1993-03-31
FI864191A0 (fi) 1986-10-16
FI83866B (fi) 1991-05-31
JPS6299359A (ja) 1987-05-08
IE60480B1 (en) 1994-07-13
US4918094A (en) 1990-04-17
FI83866C (fi) 1991-09-10
PT83558A (en) 1986-11-01
HU197724B (en) 1989-05-29
HUT42441A (en) 1987-07-28
EP0220066B1 (en) 1992-03-25
IL80335A (en) 1990-02-09
CA1336192C (en) 1995-07-04
AU6398586A (en) 1987-04-30
EP0220066A3 (en) 1988-10-12
NO170482B (no) 1992-07-13
EP0220066A2 (en) 1987-04-29
KR900004385B1 (ko) 1990-06-23
DE3684549D1 (de) 1992-04-30
GB8623429D0 (en) 1986-11-05
NZ217962A (en) 1990-03-27
KR870003983A (ko) 1987-05-06
US5049576A (en) 1991-09-17
DK495886A (da) 1987-04-18
DK495886D0 (da) 1986-10-16
HK18197A (en) 1997-02-13
NO864130D0 (no) 1986-10-16

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Legal Events

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