NO167187C - Fremgangsmaate til fremstilling av et legemiddel. - Google Patents

Fremgangsmaate til fremstilling av et legemiddel.

Info

Publication number
NO167187C
NO167187C NO842978A NO842978A NO167187C NO 167187 C NO167187 C NO 167187C NO 842978 A NO842978 A NO 842978A NO 842978 A NO842978 A NO 842978A NO 167187 C NO167187 C NO 167187C
Authority
NO
Norway
Prior art keywords
denotes
phe
formula
physiologically acceptable
medicine
Prior art date
Application number
NO842978A
Other languages
English (en)
Norwegian (no)
Other versions
NO842978L (no
NO167187B (no
Inventor
Ulrich Grau
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO842978L publication Critical patent/NO842978L/no
Publication of NO167187B publication Critical patent/NO167187B/no
Publication of NO167187C publication Critical patent/NO167187C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO842978A 1983-07-22 1984-07-20 Fremgangsmaate til fremstilling av et legemiddel. NO167187C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833326473 DE3326473A1 (de) 1983-07-22 1983-07-22 Pharmazeutisches mittel zur behandlung des diabetes mellitus

Publications (3)

Publication Number Publication Date
NO842978L NO842978L (no) 1985-01-23
NO167187B NO167187B (no) 1991-07-08
NO167187C true NO167187C (no) 1991-10-16

Family

ID=6204661

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842978A NO167187C (no) 1983-07-22 1984-07-20 Fremgangsmaate til fremstilling av et legemiddel.

Country Status (19)

Country Link
US (1) US4608364A (th)
EP (1) EP0132769B1 (th)
JP (1) JPS6042334A (th)
AT (1) ATE31625T1 (th)
AU (1) AU564648B2 (th)
CA (1) CA1236012A (th)
DE (2) DE3326473A1 (th)
DK (1) DK172456B1 (th)
ES (1) ES8504456A1 (th)
FI (1) FI79786C (th)
GR (1) GR81550B (th)
HU (1) HUT34889A (th)
IE (1) IE57690B1 (th)
IL (1) IL72468A (th)
NO (1) NO167187C (th)
NZ (1) NZ208960A (th)
PH (1) PH21328A (th)
PT (1) PT78941A (th)
ZA (1) ZA845621B (th)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
US4946828A (en) * 1985-03-12 1990-08-07 Novo Nordisk A/S Novel insulin peptides
ES2053723T3 (es) * 1987-02-25 1994-08-01 Novo Nordisk As Nuevos derivados de insulina.
US4764592A (en) * 1987-04-23 1988-08-16 Eli Lilly And Company Crystalline human proinsulin and process for its production
DE3717370A1 (de) * 1987-05-22 1988-12-01 Hoechst Ag Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus
US4789660A (en) * 1987-09-10 1988-12-06 American Home Products Corporation Insulin administration using methyl and propyl paraben
US6875589B1 (en) 1988-06-23 2005-04-05 Hoechst Aktiengesellschaft Mini-proinsulin, its preparation and use
EP0347781B1 (de) * 1988-06-23 1994-02-16 Hoechst Aktiengesellschaft Mini-Proinsulin, seine Herstellung und Verwendung
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
IL99699A (en) * 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
WO1992010284A2 (en) 1990-12-07 1992-06-25 Cnc Development, Inc. Catalytic chemical reactor
YU66892A (sh) * 1991-08-20 1995-10-24 Hoechst Ag. Fosfoinositolglikan - peptid sa delovanjem kao insulin
TW224471B (th) * 1991-11-26 1994-06-01 Lilly Co Eli
DK0545198T3 (da) * 1991-11-29 2000-03-20 Hoechst Ag Peptider med insulinagtig virkning
CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
DK72793D0 (da) * 1993-06-21 1993-06-21 Novo Nordisk As Nyt produkt
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
US5547929A (en) * 1994-09-12 1996-08-20 Eli Lilly And Company Insulin analog formulations
US6451970B1 (en) * 1996-02-21 2002-09-17 Novo Nordisk A/S Peptide derivatives
SE520392C2 (sv) 1996-09-27 2003-07-01 Creative Peptides Sweden Ab C Specifika peptider för behandling av diabetes mellitus
DE19649350A1 (de) * 1996-11-28 1998-06-04 Hoechst Ag Inositolglykane mit insulinartiger Wirkung
HUP0004169A3 (en) 1997-10-24 2001-06-28 Lilly Co Eli Insoluble insulin compositions and process for production thereof
US6444641B1 (en) 1997-10-24 2002-09-03 Eli Lilly Company Fatty acid-acylated insulin analogs
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
ES2208305T3 (es) * 1999-04-08 2004-06-16 Genentech, Inc. Composicion basada en polipeptidos de carga opuesta..
WO2002067969A2 (en) 2001-02-21 2002-09-06 Medtronic Minimed, Inc. Stabilized insulin formulations
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
GB0323979D0 (en) 2003-10-13 2003-11-19 Creative Peptides Sweden Ab Therapeutic applications for c-peptide
GB0601950D0 (en) * 2006-01-31 2006-03-15 Creative Peptides Sweden Ab Compositions and methods of treating diabetes
DE102006031955A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
EP2350118B1 (en) 2008-09-19 2016-03-30 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
PH12011502708B1 (en) 2009-07-06 2017-11-10 Sanofi Aventis Deutschland Insulin preparations containing methionine
US8410049B2 (en) 2009-10-28 2013-04-02 Cebix Methods and kits for preventing hypoglycemia
SG10201500871TA (en) 2009-11-13 2015-04-29 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
JP5832439B2 (ja) 2009-11-13 2015-12-16 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト、インスリン及びメチオニンを含む薬学的組成物
CN103179978A (zh) 2010-08-30 2013-06-26 赛诺菲-安万特德国有限公司 Ave0010用于制造供治疗2型糖尿病用的药物的用途
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
JP6367115B2 (ja) 2011-08-29 2018-08-01 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病患者の血糖コントロールに使用する組合せ医薬
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
US10689430B2 (en) * 2016-05-25 2020-06-23 Merck Sharp & Dohme Corp. Insulin receptor partial agonists
WO2025068976A1 (en) 2023-09-28 2025-04-03 Biotts Inc. Compositions comprising insulin agonists, and said compositions for use in the treatment of diabetes or obesity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP1982004086A (es) * 1981-08-27 1988-03-22 Lilly Co Eli Formula farmaceutica que comprende insulina humana y proinsulina humana
IL66611A0 (en) * 1981-08-27 1982-12-31 Lilly Co Eli Pharmaceutical formulations comprising human insulin and human c-peptide
CH650677A5 (de) * 1981-08-27 1985-08-15 Lilly Co Eli Gegen diabetes mellitus wirksames pharmazeutisches mittel.
IL66612A (en) * 1981-08-27 1985-11-29 Lilly Co Eli Pharmaceutical formulations comprising human insulin,human c-peptide,and human proinsulin
NL8201650A (nl) * 1982-04-21 1983-11-16 Akzo Nv Semisynthetische bereiding van humane insuline.

Also Published As

Publication number Publication date
DE3326473A1 (de) 1985-01-31
JPS6042334A (ja) 1985-03-06
DK172456B1 (da) 1998-08-24
HUT34889A (en) 1985-05-28
IE57690B1 (en) 1993-03-10
DK358384D0 (da) 1984-07-20
AU3091784A (en) 1985-01-24
FI79786C (fi) 1990-03-12
EP0132769A1 (de) 1985-02-13
JPH0469128B2 (th) 1992-11-05
GR81550B (th) 1984-12-11
DE3468323D1 (en) 1988-02-11
IE841890L (en) 1985-01-22
ATE31625T1 (de) 1988-01-15
PH21328A (en) 1987-10-13
EP0132769B1 (de) 1988-01-07
FI842915L (fi) 1985-01-23
FI79786B (fi) 1989-11-30
IL72468A0 (en) 1984-11-30
NO842978L (no) 1985-01-23
PT78941A (de) 1984-08-01
ZA845621B (en) 1985-02-27
ES534488A0 (es) 1985-05-01
AU564648B2 (en) 1987-08-20
US4608364A (en) 1986-08-26
IL72468A (en) 1989-08-15
FI842915A0 (fi) 1984-07-19
ES8504456A1 (es) 1985-05-01
NZ208960A (en) 1989-02-24
NO167187B (no) 1991-07-08
DK358384A (da) 1985-01-23
CA1236012A (en) 1988-05-03

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