YU66892A - Fosfoinositolglikan - peptid sa delovanjem kao insulin - Google Patents

Fosfoinositolglikan - peptid sa delovanjem kao insulin

Info

Publication number
YU66892A
YU66892A YU66892A YU66892A YU66892A YU 66892 A YU66892 A YU 66892A YU 66892 A YU66892 A YU 66892A YU 66892 A YU66892 A YU 66892A YU 66892 A YU66892 A YU 66892A
Authority
YU
Yugoslavia
Prior art keywords
insulin
phosphoinosytolglican
peptid
action
phosphoinositolglycan
Prior art date
Application number
YU66892A
Other languages
English (en)
Inventor
G. Muller
D. Tripier
S. Mullner
Original Assignee
Hoechst Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag. filed Critical Hoechst Ag.
Priority to HR940834A priority Critical patent/HRP940834B1/xx
Publication of YU66892A publication Critical patent/YU66892A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

FOSFOINOSITOLGLIKAN - PEPTID SA DELOVANJEM KAO INSULIN, opisuju se fosfoinositolglikan-peptidi, koji se dobijaju cepanjem cikličnog adenozin-3',5'-monofosfat-vezivnog proteina, koji sadrže glikozamin, galaktozu, manozu, inozitol, fosfomu kiselinu, etanolamin i jedan peptid sa sekvencom Asn-Cys-Tyr, njihova proizvodnja i primena kod tretmana šećeme bolesti (dijabetesa melitusa) i insulin rezistentnog dijabetesa.
YU66892A 1991-08-20 1992-07-02 Fosfoinositolglikan - peptid sa delovanjem kao insulin YU66892A (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HR940834A HRP940834B1 (en) 1991-08-20 1994-10-26 Phosphoinositolglycan-peptide wiht insulin like activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4127495 1991-08-20

Publications (1)

Publication Number Publication Date
YU66892A true YU66892A (sh) 1995-10-24

Family

ID=6438668

Family Applications (1)

Application Number Title Priority Date Filing Date
YU66892A YU66892A (sh) 1991-08-20 1992-07-02 Fosfoinositolglikan - peptid sa delovanjem kao insulin

Country Status (22)

Country Link
US (1) US5624903A (sh)
EP (1) EP0532915B1 (sh)
JP (1) JP3361126B2 (sh)
KR (2) KR100264623B1 (sh)
AT (1) ATE147407T1 (sh)
AU (1) AU656396B2 (sh)
CA (1) CA2076424C (sh)
CZ (1) CZ290341B6 (sh)
DE (1) DE59207835D1 (sh)
DK (1) DK0532915T3 (sh)
ES (1) ES2096686T3 (sh)
FI (1) FI102842B (sh)
GR (1) GR3022895T3 (sh)
HR (1) HRP940834B1 (sh)
HU (1) HU210431B (sh)
IL (1) IL102859A (sh)
NO (1) NO303452B1 (sh)
SG (1) SG46639A1 (sh)
SK (1) SK281333B6 (sh)
TW (1) TW224104B (sh)
YU (1) YU66892A (sh)
ZA (1) ZA926232B (sh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG46640A1 (en) * 1991-11-29 1998-02-20 Hoechst Ag Peptides with an insulin like action
ATE201442T1 (de) * 1992-02-29 2001-06-15 Aventis Res & Tech Gmbh & Co Komplexe enthaltend glykosyl-phosphatidylinositol-proteine und cholansäurederivate, verfahren zu ihrer herstellung und ihre verwendung
US5652221A (en) * 1994-11-07 1997-07-29 The University Of Virginia Patent Foundation Method of treating defective glucose metabolism using synthetic insulin substances
GB9618930D0 (en) * 1996-09-11 1996-10-23 Univ London Metal containing carbohydrates from human tissue which regulate lipogenic activity
GB9618929D0 (en) 1996-09-11 1996-10-23 Univ London Metal containing carbohydrates from human tissue which regulate glycogen metabolism
GB9618934D0 (en) * 1996-09-11 1996-10-23 Univ London Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity
DE19649350A1 (de) * 1996-11-28 1998-06-04 Hoechst Ag Inositolglykane mit insulinartiger Wirkung
KR100481746B1 (ko) * 1996-11-28 2005-08-10 훽스트 악티엔게젤샤프트 인슐린-유사작용을갖는이노시톨글리칸및이를포함하는약제학적제제
ES2245114T3 (es) 1998-08-06 2005-12-16 Mountain View Pharmaceuticals, Inc. Conjugados de peg-oxidasa de urato y su uso.
CH697081A5 (de) * 2002-01-22 2008-04-30 Andreas F Dr Schaub Zusammensetzung für die Unterstützung der Geburt eines menschlichen Föten.
EP1378517A1 (en) 2002-07-05 2004-01-07 Aventis Pharma Deutschland GmbH Phosphoinositolglycan (PIG) binding protein from adipocytes
US7943594B2 (en) * 2002-07-10 2011-05-17 Massachusetts Institute Of Technology Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans
ITMI20030237A1 (it) * 2003-02-11 2004-08-12 Indena Spa Uso della conglutina di lupino per il trattamento del
DE102004054552A1 (de) * 2004-11-11 2006-05-18 Hcb Happy Child Birth Holding Ag Neue Zusammensetzung zur Erleichterung der Humangeburt
CN101194016B (zh) 2005-04-11 2012-09-05 萨文特医药公司 尿酸氧化酶的变体形式及其用途
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
PT3321359T (pt) 2005-04-11 2021-03-11 Horizon Pharma Rheumatology Llc Formas variantes de urato-oxidase e a sua utilização
SG10201408480RA (en) 2009-06-25 2015-02-27 Crealta Pharmaceuticals Llc Methods for preventing or predicting infusion reactions or antibody-mediated loss of response, by monitoring serum uric acid levels during pegylated uricase therapy
CN102270762B (zh) * 2010-06-03 2014-08-20 清华大学 锂离子电池电极浆料及应用该电极浆料制备的电极片

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
US4839466A (en) * 1986-04-11 1989-06-13 The Rockefeller University Insulin activity messengers
US4906468A (en) * 1986-04-11 1990-03-06 The Rockefeller University Insulin activity messengers, their antibodies, and thereof

Also Published As

Publication number Publication date
KR930004327A (ko) 1993-03-22
FI923702A0 (fi) 1992-08-18
FI102842B1 (fi) 1999-02-26
ATE147407T1 (de) 1997-01-15
FI102842B (fi) 1999-02-26
AU656396B2 (en) 1995-02-02
EP0532915A2 (de) 1993-03-24
KR100264623B1 (ko) 2000-09-01
EP0532915A3 (en) 1994-05-18
GR3022895T3 (en) 1997-06-30
ZA926232B (en) 1993-04-28
KR100318706B1 (ko) 2001-12-28
CA2076424A1 (en) 1993-02-21
SK281333B6 (sk) 2001-02-12
DK0532915T3 (da) 1997-07-07
TW224104B (sh) 1994-05-21
HRP940834A2 (en) 1997-04-30
ES2096686T3 (es) 1997-03-16
SG46639A1 (en) 1998-02-20
NO923252D0 (no) 1992-08-19
JPH05301891A (ja) 1993-11-16
JP3361126B2 (ja) 2003-01-07
NO923252L (no) 1993-02-22
EP0532915B1 (de) 1997-01-08
HU210431B (en) 1995-04-28
HRP940834B1 (en) 2000-08-31
CZ255392A3 (en) 1993-03-17
DE59207835D1 (de) 1997-02-20
CZ290341B6 (cs) 2002-07-17
FI923702A (fi) 1993-02-21
IL102859A0 (en) 1993-01-31
CA2076424C (en) 2003-06-03
IL102859A (en) 1998-12-27
US5624903A (en) 1997-04-29
HUT62013A (en) 1993-03-29
SK255392A3 (en) 1995-02-08
NO303452B1 (no) 1998-07-13
AU2110992A (en) 1993-02-25

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