DK0532915T3 - phoshoinositolglycan-peptid med insulinagtig virkning - Google Patents

phoshoinositolglycan-peptid med insulinagtig virkning

Info

Publication number
DK0532915T3
DK0532915T3 DK92113897.0T DK92113897T DK0532915T3 DK 0532915 T3 DK0532915 T3 DK 0532915T3 DK 92113897 T DK92113897 T DK 92113897T DK 0532915 T3 DK0532915 T3 DK 0532915T3
Authority
DK
Denmark
Prior art keywords
insulin
phoshoinositol
action
glycan peptide
peptide
Prior art date
Application number
DK92113897.0T
Other languages
English (en)
Inventor
Dominique Dr Tripier
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0532915T3 publication Critical patent/DK0532915T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0827Tripeptides containing heteroatoms different from O, S, or N
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1027Tetrapeptides containing heteroatoms different from O, S, or N
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92113897.0T 1991-08-20 1992-08-14 phoshoinositolglycan-peptid med insulinagtig virkning DK0532915T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4127495 1991-08-20

Publications (1)

Publication Number Publication Date
DK0532915T3 true DK0532915T3 (da) 1997-07-07

Family

ID=6438668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92113897.0T DK0532915T3 (da) 1991-08-20 1992-08-14 phoshoinositolglycan-peptid med insulinagtig virkning

Country Status (22)

Country Link
US (1) US5624903A (da)
EP (1) EP0532915B1 (da)
JP (1) JP3361126B2 (da)
KR (2) KR100264623B1 (da)
AT (1) ATE147407T1 (da)
AU (1) AU656396B2 (da)
CA (1) CA2076424C (da)
CZ (1) CZ290341B6 (da)
DE (1) DE59207835D1 (da)
DK (1) DK0532915T3 (da)
ES (1) ES2096686T3 (da)
FI (1) FI102842B (da)
GR (1) GR3022895T3 (da)
HR (1) HRP940834B1 (da)
HU (1) HU210431B (da)
IL (1) IL102859A (da)
NO (1) NO303452B1 (da)
SG (1) SG46639A1 (da)
SK (1) SK281333B6 (da)
TW (1) TW224104B (da)
YU (1) YU66892A (da)
ZA (1) ZA926232B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0545198T3 (da) * 1991-11-29 2000-03-20 Hoechst Ag Peptider med insulinagtig virkning
ES2159283T3 (es) * 1992-02-29 2001-10-01 Aventis Res & Tech Gmbh & Co Complejos que contienen glicosil-fosfatidilinositol-proteinas y derivados de acido colanico, procedimiento para su preparacion y su utilizacion.
US5652221A (en) * 1994-11-07 1997-07-29 The University Of Virginia Patent Foundation Method of treating defective glucose metabolism using synthetic insulin substances
GB9618930D0 (en) 1996-09-11 1996-10-23 Univ London Metal containing carbohydrates from human tissue which regulate lipogenic activity
GB9618934D0 (en) 1996-09-11 1996-10-23 Univ London Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity
GB9618929D0 (en) 1996-09-11 1996-10-23 Univ London Metal containing carbohydrates from human tissue which regulate glycogen metabolism
KR100481746B1 (ko) * 1996-11-28 2005-08-10 훽스트 악티엔게젤샤프트 인슐린-유사작용을갖는이노시톨글리칸및이를포함하는약제학적제제
DE19649350A1 (de) * 1996-11-28 1998-06-04 Hoechst Ag Inositolglykane mit insulinartiger Wirkung
ATE498409T1 (de) 1998-08-06 2011-03-15 Mountain View Pharmaceuticals Peg-uricase konjugate und verwendung davon
CH697081A5 (de) * 2002-01-22 2008-04-30 Andreas F Dr Schaub Zusammensetzung für die Unterstützung der Geburt eines menschlichen Föten.
EP1378517A1 (en) * 2002-07-05 2004-01-07 Aventis Pharma Deutschland GmbH Phosphoinositolglycan (PIG) binding protein from adipocytes
WO2004005532A2 (en) * 2002-07-10 2004-01-15 Massachusetts Institute Of Technology Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans
ITMI20030237A1 (it) * 2003-02-11 2004-08-12 Indena Spa Uso della conglutina di lupino per il trattamento del
DE102004054552A1 (de) * 2004-11-11 2006-05-18 Hcb Happy Child Birth Holding Ag Neue Zusammensetzung zur Erleichterung der Humangeburt
WO2006110819A2 (en) 2005-04-11 2006-10-19 Savient Pharmaceuticals, Inc. Variant forms of urate oxidase and use thereof
SG10201706384VA (en) 2005-04-11 2017-09-28 Crealta Pharmaceuticals Llc A variant form of urate oxidase and use thereof
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
BRPI1010069A2 (pt) 2009-06-25 2016-03-15 Savient Pharmaceuticals Inc "método para prevenir reações à infusão durante terapia por uricase peguilada em pacientes; e método para diagnosticar se um paciente tratado com uricase peguilada desenvolverá reações à infusão ou desenvolverá liberação de uricase peguilada mediada por anticorpo sem a medição de títulos de anticorpos anti-peg e anti-uricase peguilada"
CN102270762B (zh) * 2010-06-03 2014-08-20 清华大学 锂离子电池电极浆料及应用该电极浆料制备的电极片

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
US4906468A (en) * 1986-04-11 1990-03-06 The Rockefeller University Insulin activity messengers, their antibodies, and thereof
US4839466A (en) * 1986-04-11 1989-06-13 The Rockefeller University Insulin activity messengers

Also Published As

Publication number Publication date
KR100264623B1 (ko) 2000-09-01
NO923252D0 (no) 1992-08-19
CA2076424C (en) 2003-06-03
KR100318706B1 (ko) 2001-12-28
US5624903A (en) 1997-04-29
CZ255392A3 (en) 1993-03-17
CA2076424A1 (en) 1993-02-21
ZA926232B (en) 1993-04-28
TW224104B (da) 1994-05-21
HUT62013A (en) 1993-03-29
CZ290341B6 (cs) 2002-07-17
FI923702A0 (fi) 1992-08-18
JP3361126B2 (ja) 2003-01-07
YU66892A (sh) 1995-10-24
HU210431B (en) 1995-04-28
ATE147407T1 (de) 1997-01-15
FI923702A (fi) 1993-02-21
AU656396B2 (en) 1995-02-02
SK281333B6 (sk) 2001-02-12
EP0532915A2 (de) 1993-03-24
NO923252L (no) 1993-02-22
KR930004327A (ko) 1993-03-22
ES2096686T3 (es) 1997-03-16
JPH05301891A (ja) 1993-11-16
EP0532915A3 (en) 1994-05-18
DE59207835D1 (de) 1997-02-20
HRP940834A2 (en) 1997-04-30
IL102859A (en) 1998-12-27
SK255392A3 (en) 1995-02-08
NO303452B1 (no) 1998-07-13
FI102842B1 (fi) 1999-02-26
EP0532915B1 (de) 1997-01-08
IL102859A0 (en) 1993-01-31
SG46639A1 (en) 1998-02-20
GR3022895T3 (en) 1997-06-30
HRP940834B1 (en) 2000-08-31
FI102842B (fi) 1999-02-26
AU2110992A (en) 1993-02-25

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