NO165921C - Fremgangsmaate for fremstilling av disubstituerte prolinderivater. - Google Patents
Fremgangsmaate for fremstilling av disubstituerte prolinderivater.Info
- Publication number
- NO165921C NO165921C NO840048A NO840048A NO165921C NO 165921 C NO165921 C NO 165921C NO 840048 A NO840048 A NO 840048A NO 840048 A NO840048 A NO 840048A NO 165921 C NO165921 C NO 165921C
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- procedure
- proline derivatives
- disubstituted
- disubstituted proline
- Prior art date
Links
- 150000003147 proline derivatives Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 101500021084 Locusta migratoria 5 kDa peptide Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
- Hydrogenated Pyridines (AREA)
- Developing Agents For Electrophotography (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Glass Compositions (AREA)
- Golf Clubs (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833300316 DE3300316A1 (de) | 1983-01-07 | 1983-01-07 | Disubstituierte prolinderivate, verfahren zu ihrer herstellung und ihre verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO840048L NO840048L (no) | 1984-07-09 |
| NO165921B NO165921B (no) | 1991-01-21 |
| NO165921C true NO165921C (no) | 1991-05-02 |
Family
ID=6187824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO840048A NO165921C (no) | 1983-01-07 | 1984-01-06 | Fremgangsmaate for fremstilling av disubstituerte prolinderivater. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4684662A (es) |
| EP (1) | EP0115639B1 (es) |
| JP (3) | JPS59144755A (es) |
| KR (1) | KR900007216B1 (es) |
| AT (1) | ATE25677T1 (es) |
| AU (1) | AU575306B2 (es) |
| CA (1) | CA1220213A (es) |
| DE (2) | DE3300316A1 (es) |
| DK (2) | DK171641B1 (es) |
| ES (2) | ES528703A0 (es) |
| FI (1) | FI81780C (es) |
| GR (1) | GR79462B (es) |
| HU (1) | HU190541B (es) |
| IE (1) | IE56520B1 (es) |
| IL (1) | IL70618A (es) |
| MA (1) | MA19996A1 (es) |
| NO (1) | NO165921C (es) |
| NZ (1) | NZ206733A (es) |
| PH (1) | PH19979A (es) |
| PT (1) | PT77924B (es) |
| ZA (1) | ZA84113B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3226768A1 (de) * | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
| CA1341296C (en) * | 1981-12-29 | 2001-09-25 | Hansjorg Urbach | 2-azabicycloalkane-3-carboxylic acid derivatives, processes for their preparation, agents containing these compounds and their use |
| US5175306A (en) * | 1983-01-31 | 1992-12-29 | Hoechst Aktiengesellschaft | Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters |
| DE3333455A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung n-alkylierter dipeptide und deren estern |
| DE3413710A1 (de) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur behandlung der herzinsuffizienz |
| US5684016A (en) * | 1984-04-12 | 1997-11-04 | Hoechst Aktiengesellschaft | Method of treating cardiac insufficiency |
| DE3431541A1 (de) * | 1984-08-28 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung |
| US5231080A (en) * | 1985-10-15 | 1993-07-27 | Hoechst Aktiengesellschaft | Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease |
| US5231084A (en) * | 1986-03-27 | 1993-07-27 | Hoechst Aktiengesellschaft | Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons |
| DE3633496A1 (de) * | 1986-10-02 | 1988-04-14 | Hoechst Ag | Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln |
| DE3639879A1 (de) * | 1986-11-21 | 1988-06-01 | Hoechst Ag | Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung |
| DE3722007A1 (de) * | 1987-07-03 | 1989-01-12 | Hoechst Ag | Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung |
| HU904967D0 (en) * | 1988-04-22 | 1991-01-28 | Hoechst Ag | Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives |
| EP0419683A4 (en) * | 1989-04-13 | 1992-03-11 | Japan Tobacco Inc. | New amino acid derivatives having prolylendopeptidase inhibitor activity |
| TW492957B (en) * | 1996-11-07 | 2002-07-01 | Novartis Ag | N-substituted 2-cyanopyrrolidnes |
| US20040152745A1 (en) * | 1999-11-12 | 2004-08-05 | Guilford Pharmaceuticals, Inc. | Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors |
| CA2390231A1 (en) * | 1999-11-12 | 2001-05-17 | Paul Jackson | Dipeptidyl peptidase iv inhibitors and methods of making and using dipeptidyl peptidase iv inhibitors |
| MXPA05010165A (es) * | 2003-04-15 | 2005-11-16 | Warner Lambert Co | Derivados de prolina biciclicos [c]-condensados y su uso para el tratamiento de estados artriticos. |
| CA2522195A1 (en) * | 2003-04-15 | 2004-10-28 | Warner-Lambert Company Llc | [b]-fused bicyclic proline derivatives and their use for treating arthritic conditions |
| CN101098679A (zh) * | 2004-11-05 | 2008-01-02 | 国王医药研究与发展有限公司 | 稳定的雷米普利组合物及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE315190C (es) * | ||||
| US4350704A (en) * | 1980-10-06 | 1982-09-21 | Warner-Lambert Company | Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids |
| US4374847A (en) * | 1980-10-27 | 1983-02-22 | Ciba-Geigy Corporation | 1-Carboxyalkanoylindoline-2-carboxylic acids |
| DE3151690A1 (de) * | 1981-12-29 | 1983-07-07 | Hoechst Ag, 6230 Frankfurt | "neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung" |
-
1983
- 1983-01-07 DE DE19833300316 patent/DE3300316A1/de not_active Withdrawn
- 1983-12-29 DE DE8383113193T patent/DE3369980D1/de not_active Expired
- 1983-12-29 AT AT83113193T patent/ATE25677T1/de not_active IP Right Cessation
- 1983-12-29 EP EP83113193A patent/EP0115639B1/de not_active Expired
-
1984
- 1984-01-02 HU HU846A patent/HU190541B/hu unknown
- 1984-01-04 GR GR73427A patent/GR79462B/el unknown
- 1984-01-05 KR KR1019840000013A patent/KR900007216B1/ko not_active IP Right Cessation
- 1984-01-05 ES ES528703A patent/ES528703A0/es active Granted
- 1984-01-05 NZ NZ206733A patent/NZ206733A/en unknown
- 1984-01-05 PT PT77924A patent/PT77924B/pt unknown
- 1984-01-05 IL IL70618A patent/IL70618A/xx not_active IP Right Cessation
- 1984-01-05 US US06/568,423 patent/US4684662A/en not_active Expired - Lifetime
- 1984-01-05 FI FI840027A patent/FI81780C/fi not_active IP Right Cessation
- 1984-01-05 PH PH30067A patent/PH19979A/en unknown
- 1984-01-06 ZA ZA84113A patent/ZA84113B/xx unknown
- 1984-01-06 DK DK006384A patent/DK171641B1/da not_active IP Right Cessation
- 1984-01-06 NO NO840048A patent/NO165921C/no not_active IP Right Cessation
- 1984-01-06 JP JP59000375A patent/JPS59144755A/ja active Granted
- 1984-01-06 MA MA20217A patent/MA19996A1/fr unknown
- 1984-01-06 CA CA000444858A patent/CA1220213A/en not_active Expired
- 1984-01-06 IE IE23/84A patent/IE56520B1/en not_active IP Right Cessation
- 1984-01-06 AU AU23146/84A patent/AU575306B2/en not_active Expired
- 1984-03-06 ES ES530311A patent/ES530311A0/es active Granted
-
1992
- 1992-03-03 JP JP4045559A patent/JPH0570423A/ja active Granted
- 1992-03-03 JP JP4045560A patent/JPH0610190B2/ja not_active Expired - Lifetime
-
1996
- 1996-03-21 DK DK033196A patent/DK171642B1/da not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |
Free format text: EXPIRED IN |