NO164295C - Analogifremgangsmaate til fremstilling av terapeutisk aktive fluorerte benzyltriazolforbindelser. - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive fluorerte benzyltriazolforbindelser.

Info

Publication number
NO164295C
NO164295C NO861486A NO861486A NO164295C NO 164295 C NO164295 C NO 164295C NO 861486 A NO861486 A NO 861486A NO 861486 A NO861486 A NO 861486A NO 164295 C NO164295 C NO 164295C
Authority
NO
Norway
Prior art keywords
fluored
benzyltriazol
compounds
preparation
therapeutic active
Prior art date
Application number
NO861486A
Other languages
English (en)
Norwegian (no)
Other versions
NO861486L (no
NO164295B (no
Inventor
Rene Meier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO861486L publication Critical patent/NO861486L/no
Publication of NO164295B publication Critical patent/NO164295B/no
Publication of NO164295C publication Critical patent/NO164295C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO861486A 1985-04-18 1986-04-16 Analogifremgangsmaate til fremstilling av terapeutisk aktive fluorerte benzyltriazolforbindelser. NO164295C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH166385 1985-04-18

Publications (3)

Publication Number Publication Date
NO861486L NO861486L (no) 1986-10-20
NO164295B NO164295B (no) 1990-06-11
NO164295C true NO164295C (no) 1990-09-19

Family

ID=4215715

Family Applications (1)

Application Number Title Priority Date Filing Date
NO861486A NO164295C (no) 1985-04-18 1986-04-16 Analogifremgangsmaate til fremstilling av terapeutisk aktive fluorerte benzyltriazolforbindelser.

Country Status (22)

Country Link
EP (1) EP0199262B1 (fr)
JP (1) JPS61243068A (fr)
KR (1) KR900008810B1 (fr)
AU (1) AU599024B2 (fr)
CA (1) CA1272201A (fr)
CY (1) CY1751A (fr)
DD (1) DD245874A5 (fr)
DE (1) DE3677626D1 (fr)
DK (1) DK169720B1 (fr)
ES (2) ES8800176A1 (fr)
FI (1) FI93544C (fr)
GR (1) GR861004B (fr)
HK (1) HK1494A (fr)
HU (1) HU203327B (fr)
IE (1) IE58472B1 (fr)
IL (1) IL78510A (fr)
MX (1) MX9203628A (fr)
NO (1) NO164295C (fr)
NZ (1) NZ215871A (fr)
PH (1) PH22568A (fr)
PT (1) PT82400B (fr)
ZA (1) ZA862873B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (fr) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(Amino ou amino substitué)-1,2,3-triazoles
AU2633897A (en) * 1996-04-19 1997-11-12 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
BR9710252B1 (pt) * 1996-07-11 2010-06-29 processo para preparar4 4-ciano-1,2,3-triazóis 1-substituìdos.
TW526195B (en) * 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
TW513301B (en) * 1999-03-01 2002-12-11 Novartis Ag Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders
WO2004106329A2 (fr) * 2003-06-03 2004-12-09 Dr. Reddy's Laboratories Ltd. Nouveaux composes anti-infectieux et compositions pharmaceutiques les contenant
IT1393368B1 (it) * 2009-03-23 2012-04-20 Dipharma Francis Srl Metodo per la preparazione di rufinamide
IT1395736B1 (it) 2009-08-04 2012-10-19 Dipharma Francis Srl Forme cristalline di rufinamide
WO2011135105A1 (fr) * 2010-04-30 2011-11-03 Laboratorios Lesvi, S.L. Procédé perfectionné pour la préparation d'un intermédiaire pour la préparation de rufinamide
ITMI20110718A1 (it) 2011-04-29 2012-10-30 Dipharma Francis Srl Procedimento per la purificazione di rufinamide
WO2014120994A1 (fr) * 2013-01-31 2014-08-07 The Johns Hopkins University Rufinamide et dérivés et leur utilisation pour moduler le processus de dépendance des canaux sodiques voltage-dépendants humains
US9771335B2 (en) * 2015-07-31 2017-09-26 The Johns Hopkins University Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels
CA3008048C (fr) 2015-12-11 2023-11-14 Aarhus Universitet Rufinamide pour son utilisation dans le traitement de la myotonie
WO2021099481A1 (fr) 2019-11-20 2021-05-27 Medichem, S.A. Composition solide contenant du rufinamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
FI834666A (fi) * 1982-12-23 1984-06-24 Ciba Geigy Ag Foerfarande foer framstaellning av nya aralkyltriazolfoereningar.

Also Published As

Publication number Publication date
AU599024B2 (en) 1990-07-12
ES557641A0 (es) 1988-07-01
HU203327B (en) 1991-07-29
DK175686D0 (da) 1986-04-17
CA1272201A (fr) 1990-07-31
NZ215871A (en) 1989-01-27
DE3677626D1 (de) 1991-04-04
FI861573A0 (fi) 1986-04-14
NO861486L (no) 1986-10-20
PH22568A (en) 1988-10-17
DK175686A (da) 1986-10-19
PT82400A (en) 1986-05-01
IE58472B1 (en) 1993-09-22
FI93544B (fi) 1995-01-13
DK169720B1 (da) 1995-01-23
KR900008810B1 (ko) 1990-11-30
PT82400B (pt) 1988-08-17
KR860008152A (ko) 1986-11-12
HUT40792A (en) 1987-02-27
ES554024A0 (es) 1987-10-16
GR861004B (en) 1986-08-12
ES8800176A1 (es) 1987-10-16
EP0199262A2 (fr) 1986-10-29
JPH0564949B2 (fr) 1993-09-16
HK1494A (en) 1994-01-14
IE861015L (en) 1986-10-18
ES8802501A1 (es) 1988-07-01
MX9203628A (es) 1992-09-01
EP0199262A3 (en) 1987-08-26
FI93544C (fi) 1995-04-25
JPS61243068A (ja) 1986-10-29
IL78510A (en) 1992-05-25
CY1751A (en) 1994-06-03
NO164295B (no) 1990-06-11
ZA862873B (en) 1986-12-30
FI861573A (fi) 1986-10-19
EP0199262B1 (fr) 1991-02-27
AU5631986A (en) 1986-10-23
DD245874A5 (de) 1987-05-20
IL78510A0 (en) 1986-08-31

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